Wetin na MOGAD? Lɛ wi lan bɔt dis sik we de pwɛl wi yon bɔdi pat!

Yu dɔn ɛva wɔnda aw wi imyun sistɛm, we tan lɛk sojaman we de protɛkt wi frɔm sik, kin go rɔng sɔntɛnde ɛn atak wi yon pat dɛn we gɛt wɛlbɔdi ? Bɔt i sɔri fɔ no se dis na sik we kin kam wit prɔblɛm we kin apin insay wi bɔdi. Pan ɔl we dis kin tan lɛk se i kɔmplikt smɔl, lɛ wi kip am simpul bikɔs i impɔtant fɔ no bɔt am.

Wetin rili na MOGAD?

Fɔ tɔk am simpul wan, MOGAD na wan sik we pɔsin kin gɛt we i de fɛt insɛf . Naw yu go de wɔnda wetin i bi. Di men wok we wi bɔdi in imyun sistɛm de du na fɔ protɛkt wi frɔm sik dɛn bay we i de fɛt di jem, vayrɔs, ɛn baktri dɛm we de kɔmɔt na do. Dis kin ɛp bay wan spɛshal kayn prɔtin we dɛn kɔl antibodi . Bɔt sɔntɛnde, dis imyun sistɛm kin go rɔng. Dɔn dɛn kin bigin fɔ no wi yon wɛlbɔdi sɛl ɛn tisu dɛn as ɛnimi ɛn atak dɛn. Na dat wi kin kɔl ɔtoimyun kɔndishɔn.

Na dat de apin na MOGAD. na ya, wi imyun sistεm de atak di protεktiv kכva we de rawnd wi sεntri nεv sεstem (CNS) , we na di bren, spεnal kכd, εn optik nεv dεm na wi yay. Dɛn kɔl dis kɔva we de protɛkt am maylin . Tink bɔt am lɛk di plastic sheath we de rawnd ilɛktrik waya. dis maylin de protεkt di nεv fayb dεm εn i de εp di nεv signal dεm fכ travul fayn fayn wan.

So, we antibodi dεm kam εn pwεl dis maylin, wi kin kכl am demyelination . Jɔs lɛk we di plastic we de kɔba da waya de pwɛl, di layt nɔ de ɔn fayn, we di maylin dɔn pwɛl, di mɛsej dɛn we de kɔmɔt na di bren to di ɔda pat dɛn na di bɔdi nɔ de go tru fayn fayn wan. Dis na di rizin we mek MOGAD kin mek pipul dɛn gɛt difrɛn sayn dɛn.

Di kɔmɔn simptom dɛm na we yu nɔ de si ɔ yu nɔ de si fayn (Optic Neuritis) , yu mɔsul dɛn wik (Transverse Myelitis) , ɛn yu nɔ de balans (Acute Disseminated Encephalomyelitis - ADEM) . If dɔktɔ kɔl yu wit dɛn nem ya, yu go no naw wetin dɛn min.

Yu tink se men kayn MOGAD de?

Yɛs, wi kin si tu men kayn MOGAD:

1. Monophasic MOGAD: Insay dis kes, yu kin jɔs gɛt di simptom dɛn wan tɛm. Dat min se, wans yu gɛt di sik ɛn dɛn dɔn trit yu, di sayn dɛm nɔ de sho igen.

2. Rilaps MOGAD: Dis na difrent likl. Di sayn dɛm kin dɔn fɔ sɔm tɛm (wi kin kɔl dis rεmishɔn) , bɔt afta dat i kin kam bak. I tan lɛk se na sik we nɔ de mɛn.

Yu tink se MOGAD na sik we nɔ kin bɔku?

Wetin MOGAD rili min?Wan disɔda we nɔ kin apin so ɔltɛm we de mek pɔsin nɔ ebul fɔ du mami ɛn dadi biznɛs . Bɔt as pipul dɛn de no mɔ bɔt dis sik, dɔktɔ dɛn biliv se i go mɔs bi se di wan dɛn we gɛt di sik go bɔku tumara bambay. Frɔm di tin dɛn we dɛn dɔn lan naw, dɛn se na lɛk wan to tri pipul dɛn pan wan milyɔn pipul dɛn kin gɛt dis sik ɛvri ia. Dat min se i nɔto sik we bɔku pipul dɛn kin gɛt.

Wetin na di sayn dɛm fɔ MOGAD?

Di sayn dɛm fɔ MOGAD kin afɛkt bɔku pat dɛm na yu bɔdi. di men wan dεm na di yay, di spεnal kכd (di nεv kכd we de insay di spayna), εn di bren.

Di sayn dɛm wae de afɛkt di yay (Optic Neuritis) .

Wi kin kɔl dis kɔndishɔn Optik Nyuraytis . I kin afɛkt wan ɔ ɔl tu yay.

• Di vishɔn we nɔ klia
• Dabl vishɔn
• Sɔm pat ɔ kɔmplit lɔs pan di vishɔn
• Ay pen , mɔ we yu de muv yu yay
• Kɔlɔ we nɔ de si fayn

Imajin, wantɛm wantɛm yu go lɔs yu yay na wan yay, ɔ ɔltin go blɔk. Na so ɛkspiriɛns kin tan lɛk.

Di simptom dɛm wae de afɛkt di spɛshal kɔd (Transverse Myelitis) .

Dɛn kɔl dis transvas maylaytis . Dis na inflameshn na di spεnal kכd.

• Mɔsul dɛn wik , sɔntɛm ivin nɔ ebul fɔ waka
• Sɔm pat dɛn na di bɔdi kin swɛla ɔ nɔ kin fil fayn
• di lכs fכ kכntrכl di bכdi כ di blad (e.g., i nכ ebul fכ ol di urine, i nכ ebul fכ kכntrכl di bכdi muvmεnt)
• I nɔ izi fɔ mek yu nɔ gɛt urine kɔmplit wan
• Di mɔsul dɛn we de stif ɔ we de twitch (spasticity) .
• Shap pen we yu de chuk yu ɔ yu de fil lɛk yu de swɛt na yu nɛk, yu bak, ɔ yu bɛlɛ .

Dis tan lɛk we di men kebul we de kɛr mɛsej dɛn na wi bɔdi dɔn pwɛl.

Di sayn dɛm wae de afɛkt di bren (ADEM) .

Wi kin kɔl di simptom dɛm we de afɛkt di bren Acute Disseminated Encephalomyelitis (ADEM) .

• Kɔnfyushɔn , fil lɛk se yu kɔnshɛns de waka waka
• Lɔs fɔ balans ɛn kɔdineshɔn , kin sway lɛk pɔsin we dɔn chak
• Ed de at
• Di chenj we pɔsin de biev , lɛk fɔ vɛks ɔ fɔ vɛks
• Lɔs fɔ no bɔt sɔntin
• Epilepsy symptoms (Seizures) , dat na, yu kin gɛt sik.

MOGAD simptom kin de kam bak. Dat min se, sɔm tɛm dɛn kin de we nɔ gɛt ɛni sayn ɛn afta dat wantɛm wantɛm di sik kin kam bak (rilaps).

Di sayn dɛm fɔ MOGAD difrɛn fɔ big pipul ɛn pikin dɛm?

Yɛs, di we aw di sik kin apin kin chenj smɔl wit di ej.

כltu, we pikin dεn gεt MOGAD, i kin mεnli afekt di bren (ADEM kכndishכn). Dɔn di sayn dɛm wae wi bin dɔn tɔk bɔt, lɛk fɔ kɔnfyus ɛn nɔr de balans, na dɛn kin si bɔrku tɛm. Sɔmtɛm, prɔblɛm wit yu yay (Optic Neuritis) kin apin bak di sem tɛm.

we big pipul dεn gεt MOGAD, i kin tכk bכku tεm di spεnal kכd (Transverse Myelitis) εn di yay dεm (Optic Neuritis). So, bɔrku tɛm dɛn kin gɛt sɔm kayn sayn dɛm lɛk fɔ wik, nɔr kin fil fayn, ɛn nɔr kin si fayn fayn wan.

Wetin mek dɛn mek MOGAD?

Fɔ tɔk tru, dɛn nɔ dɔn fɛn di rayt rizin fɔ MOGAD yet . Naw dɛn biliv se dis nɔto sik we pɔsin kin gɛt frɔm in mama ɛn papa ɔ sik we pɔsin kin gɛt bikɔs ɔf in jɛnɛtiks. Risach de bak fɔ no if i kin bigin bikɔs ɔf chenj na di imyun sistɛm, lɛk afta wan vayral infɛkshɔn. Bɔt i nɔ pɔsibul yet fɔ tɔk fɔ tru se na dis mek i apin.

Wetin na di prɔblɛm dɛn we pɔsin kin gɛt we i gɛt MOGAD?

Di damej pan da kɔva we de protɛkt wi we dɛn kɔl maylin kin gɛt ɛfɛkt fɔ ɔltɛm pan aw wi bɔdi de wok. Sɔm pan di prɔblɛm dɛn we kin apin sɔntɛnde na:

• Fɔ bi blaynd kpatakpata
• Di blad ɔ di bɔdi nɔ de wok fɔ ɔltɛm
• Paralayz we pɔsin kin gɛt
• Pen we nɔ de dɔn
• Chronic fatigue , fɔ fil taya ɔltɛm
• Cognitive impairment , we min se i nɔ kin izi fɔ lan, mɛmba, ɛn tink.

Fɔ liv wit MOGAD nɔmɔ kin rili at fɔ manej. Wae de sik kin kam, e kin tek yu komot pan de tin wae yu kin gladi fɔ du ɛn mek yu fil se yu nɔr ebul fɔ du natin. Dis kin mek bɔrku pipul dɛm wae gɛt MOGAD kin sɔfa bak wit mɛntɛl hεlth prɔblɛm lɛk pwɛl hat. So, if yu de fil dis kayn we, i impɔtant fɔ tɔk to dɔktɔ bɔt am.

Aw dɛn kin no se pɔsin gɛt MOGAD sik?

Dɔktɔ go no se i gɛt MOGAD bay we i du wan ɛgzam pan in bɔdi , wan ɛgzam fɔ di nyurolɔjik , ɛn sɔm ɔda spɛshal tɛst dɛn . We dɛn de du di ɛgzam, i go aks bɔt yu sik dɛn ɛn yu mɛdikal istri.

Tεst dεm wae de εp fכ kכnfכm di prεsεns כf MOGAD sik inklud:

• chɛk if di nɔmba fɔ di wayt blɔd sɛl dɛn na di blɔd dɔn bɔku (dis na sɔntin we kin apin we inflamɛns de).
• If ɛni lɛsin de na di bren ɔ di spɛshal kɔd (dɛn kin chɛk dɛn tin ya wit MRI skan).
• Oligoklɔnal band dɛnDɛn nɔ kin si dɛn tin ya na MOGAD, bɔt dɛn kin si dɛn na sɔm ɔda sik dɛn (e.g., multiple sclerosis). Dis kin ɛp fɔ no difrɛns bitwin di tu sik dɛm.

Sɔm tɛst dɛm wae kin yus fɔ no bɔt MOGAD na:

• bכdi tεst: Chεk fכ antibodi dεm spεshal wan agens wan protin we dεn kכl MOG (MOG-IgG antibodies).
• Vision exam: Chεk fכ inflameshn na di optik nerve.
• lכmba pankshכn: Dis min fכ tek sכm sכm sכm sכm sεribrospεnal wata frכm di spayna εn tεst am. dεn kכl dis bak "spinal tap."
• MRI (Magnetic Resonance Imaging) scan: Dis kin tek ditayla pikchɔ dɛn fɔ di bren ɛn di spɛshal kɔd ɛn luk fɔ lɛsin dɛn na di maylin.

Sɔntɛnde, i nɔ kin izi fɔ no bɔt MOGAD, bikɔs di sayn dɛn we i kin gɛt kin tan lɛk ɔda sik dɛn we kin kam pan pɔsin in nyuro, lɛk multiple sclerosis (MS) . So, i kin tek sɔm tɛm ɛn sɔm tɛst fɔ mek dɛn no di sik kɔrɛkt wan.

Na us ej dɛn kin no se dɛn gɛt MOGAD?

Bɔku pipul dɛn kin gɛt MOGAD we dɛn ol twɛnti ɔ tati ia . Bɔt dis sik kin afɛkt ɛnibɔdi pan ɛni ej. Bɔku tɛm dɛn kin no bɔt pikin dɛn bifo dɛn ol 11 ia .

Yu tink se dɛn kin mɛn MOGAD kpatakpata?

I sɔri fɔ no se, no mɛrɛsin nɔ de fɔ MOGAD dis tɛm . Dat min se, no mɛrɛsin nɔ de we go pul di sik kɔmɔt na di bɔdi kpatakpata. Bɔt, nɔ fred! Tritmɛnt dɛn de we kin ɛp fɔ kɔntrol di sik dɛn, fɔ ridyus di sik we dɛn kin gɛt, ɛn fɔ mek pɔsin gɛt gud kwaliti layf.

Aw dɛn kin trit MOGAD?

We di MOGAD simptom dɛn kin wɔs wantɛm wantɛm (akyu atak), sɔm tritmɛnt dɛn de we dɛn kin gɛt:

• Stɛroyd, lɛk methylprednisolone: ​​Dɛn kin gi dɛn tin ya insay di bɛlɛ fɔ tri to fayv dez. Dis kin ɛp fɔ ridyus di inflamɛns kwik kwik wan ɛn kɔntrol di sayn dɛm.
• Plasma exchange: Dis na tritmɛnt we kɔmpleks smɔl. Insay dis, wan mashin kin pul di wata we de na yu blɔd we dɛn kɔl plasma, i kin separet am frɔm di blɔd sɛl dɛn, dɔn i kin injɛkt wan wata we go tek in ples, wit yu blɔd sɛl dɛn bak insay yu bɔdi. Dis kin ɛp fɔ pul di antibodi dɛn we de ambɔg pɔsin.
• Imyunoglobulin we dɛn kin put insay di bɛlɛ (IVIG):Dis involv fɔ riples di antibodi dɛm na yu blɔd wit wɛlbɔdi antibodi dɛm frɔm di wan dɛm we de gi yu tru wan vein. dis kin kכntro bak di akshכn fכ dεn antibodi dεm we nכ de wok fayn.
• Immunosuppressant medications: Dɛn kin gi dɛn tin ya as pils we dɛn kin tek wit mɔt. Dɛn kin ridyus di wok we di imyun sistɛm de du ɛn ɛp fɔ stɔp mɔ damej.

Dɛn kin yuz sɔm mɛrɛsin dɛn bak as tritmɛnt fɔ lɔng tɛm fɔ mek dɛn nɔ gɛt MOGAD simptom dɛn bak:

• Immunosuppressant mɛrɛsin dɛn (ɔda kayn dɛn fɔ kɔntinyu fɔ yuz) .
• Maykofenolat mofetil
• Rituximab we dɛn kɔl Rituximab
• Azatiɔprin we dɛn kɔl
• IVIG (intravenous immunoglobulin) infuzכn כ sabkutan imyunoglobulin injεkshכn

Ɔl dɛn tritmɛnt ya kin gɛt sɔm bad bad tin dɛn. Yu dɔktɔ go ɛksplen ɔl dɛn tin ya to yu bifo yu bigin fɔ trit yu. I impɔtant fɔ mek yu dɔktɔ no if yu notis ɛni nyu tin.

Sɔntɛnde, if di sik de mek yu gɛt prɔblɛm, yu dɔktɔ kin tɛl yu fɔ tek pat pan program dɛn fɔ mek yu gɛt wɛlbɔdi . Fɔ ɛgzampul, if di myelin damej dɔn afɛkt yu vishɔn ɔ waka, dɛn rihabiliteshɔn program ya kin ɛp yu fɔ lan fɔ du ɛvride aktiviti ɛn fɔ go rawnd fɔ yusɛf.

Wetin na di prɔgnosis fɔ MOGAD sik?

Dɛn stil de stɔdi di prɔgnosis fɔ MOGAD. Bɔt di we aw bɔku pan di wan dɛn we sik kin si tin fayn . Sɔm pipul dɛn kin gɛt chenj na dɛn yay fɔ ɔltɛm. Dɔn bak, sɔm tritmɛnt dɛn (lɛk fɔ yuz mɛrɛsin fɔ lɔng tɛm we de mek yu bɔdi nɔ gɛt bɛtɛ trɛnk) kin mek yu gɛt sayd ɛfɛkt lɛk infɛkshɔn. So, i impɔtant fɔ fala yu dɔktɔ in instrɔkshɔn ɛn de chɛk-ap ɔltɛm.

Yu tink se MOGAD de afɛkt di layf we pɔsin de liv?

MOGAD nɔ de afɛkt yu layf span dairekt wan . Bɔku ɔda tin dɛn kin afɛkt di we aw pɔsin de liv in layf. Dipen pan yu situeshɔn, yu kin gɛt di mɔs ɔp-to-dɛt infɔmeshɔn bɔt dis frɔm yu dɔktɔ.

Yu tink se dɛn kin ebul fɔ stɔp MOGAD?

I sɔri fɔ no se, no we nɔ de we dɛn no fɔ mek dɛn nɔ gɛt MOGAD . Dɛn stil de du risach bɔt dis. Yu dɔktɔ kin tɛl yu fɔ tek pat pan klinik trial fɔ lan bɔt nyu tritmɛnt ɛn we fɔ mek yu nɔ gɛt dis sik.

Ustɛm a fɔ go to dɔktɔ?

If yu gɛt ɛni wan pan dɛn tin ya, go to dɔktɔ wantɛm wantɛm:

• If di sayn dɛn de sho wantɛm wantɛm.
• If yu notis se yu yay chenj.
• If yu gɛt prɔblɛm wit yu ebul fɔ waka ɛn muv rawnd.
• If di simptom dɛn wɔs afta dɛn dɔn trit am.
• If yu gɛt sayd ɛfɛkt frɔm tritmɛnt.

Yu sabi yu bɔdi pas ɔlman. If sɔntin nɔr fil fayn, nɔr shem fɔ tɔk to yu dɔktɔ bɔt am.

If yu si sayn dɛm fɔ epilepsy (seizure) fɔ di fɔs tɛm, kɔl imejensi rum wantɛm wantɛm.

Us kwɛstyɔn dɛn a fɔ aks mi dɔktɔ?

Na nɔmal tin fɔ gɛt bɔku kwɛstyɔn na yu maynd we yu gɛt diagnosis fɔ MOGAD.

• "Us kayn tritmɛnt dɛn kin rɛkɔmɛnd fɔ mi?"
• "A nid tritmɛnt fɔ lɔng tɛm?"
• "Wetin na di sayd ifekt dɛm fɔ di tritmɛnt?"
• "Wetin a go du if mi simptom dɛn wɔs wantɛm wantɛm?"

Nɔ fred fɔ aks dɛn kwɛstyɔn ya. Afta yu dɔn gɛt diagnosis fɔ MOGAD, na nɔmal tin fɔ fil se yu gɛt bɔku tin fɔ tink lɛk, "Wetin go apin nɛks?" ɛn "Ustɛm di sayn dɛm go kam bak?" Wae yu de liv wit wan kondishon wae den nor no de cause, dat uncertainty kin tek toll pan yu mental health. Pan ɔl we bɔku tin nɔ kin shɔ, mɛmba se yu mɛdikal tim de fɔ mek yu nɔ fred ɛn ansa yu kwɛstyɔn dɛn. Dɛn kin ɛp yu fɔ kɔntrol yu sik wae de kam ɛn tek step fɔ ridyus yu risk fɔ gɛt flare-up tumara bambay.

Wetin wi wan tek go os frɔm dis stori (Take-Home Message)

MOGAD na wan sik we kɔmpleks smɔl ɛn we nɔ kin bɔku. Bɔt i impɔtant fɔ no bɔt am ɛn ɔndastand di sayn dɛm. Mɛmba se dis nɔto sik we na yu fɔlt.

• If yu si chenj wantɛm wantɛm na yu yay, yu wik, ɔ yu nɔ ebul fɔ si , go to dɔktɔ wantɛm wantɛm.
• If dɛn no di sik ɛn trit am fayn, dɛn kin kɔntrol di sayn dɛn we de sho se pɔsin gɛt MOGAD fayn fayn wan.
• Pan ɔl we no mɛrɛsin nɔ de, we dɛn de fɔ mek pɔsin kɔntinyu fɔ liv fayn layf wit di sik.
• If yu de fil bad ɔr pwɛl hat, tɔk to dɔktɔ ɔr pɔrsin wae yu trɔst bɔt dis. Nɔto yu wan de.

A op se dis infɔmeshɔn dɔn ɛp yu fɔ gɛt sɔm ɔndastandin bɔt MOGAD. Stay wit wɛlbɔdi!

` MOGAD, כtoimyun sik dεm, maylin, nεv sεstem, optik nyuraytis, transvas maylaytis, ADEM