Yu gɛt prɔblɛm wit yu blɔd vesel dɛn? Mek wi lan bɔt Polyarteritis Nodosa!

Sɔntɛnde na wi layf wi kin yɛri bɔt sik dɛn we wi nɔ ɛva yɛri bɔt, nɔto so? Wɛl, tide wi go tɔk bɔt wan sik we nɔ kin bɔku, bɔt i rili impɔtant fɔ mek wi ɔl no bɔt. Dɛn kɔl dis Polyarteritis Nodosa , ɔ PAN fɔ shɔt tɛm. Sɔntɛm yu nɔ bin dɔn yɛri dis nem bifo. Bɔt dat nɔ bad, wi go tɔk bɔt ɔltin simpul we we yu go ɔndastand.

Wetin na dis Polyarteritis Nodosa?

Fɔ tɔk am simpul wan, polyarthritis nodosa (PAN) na wan sik we nɔ kin apin so ɔltɛm we di blɔd vesel dɛn na wi bɔdi kin inflam, ɔ swel. Insay mɛrɛsin, dɛn kɔl dis kayn we we di blɔd vesel dɛn kin swel, vaskulaytis . insay dis kכndishכn, PAN de mεntal afekt di mεdiכm saiz bכdi vεsul dεm na wi bכdi.

Tink bɔt dis we: di blɔd vesel dɛn we de ɔlsay na wi bɔdi tan lɛk wata paip. Dɛn paip ya kin kɛr di ɔksijɛn ɛn di tin dɛn we wi ɔgan dɛn nid. So, we dɛn blɔd vesel ya swel, jɔs lɛk aw wata paip kin lɔk, blɔd nɔ kin flɔ fayn fayn wan to dɛn ɔgan dɛn de. Dɔn dɛn ɔgan dɛn de nɔ kin wok fayn, ɛn sɔntɛnde i kin ivin stɔp kpatakpata.

Aw dis kin afɛkt di blɔd vesel dɛn?

Dis PAN kɔndishɔn kin pwɛl di blɔd vesel dɛn difrɛn we dɛn:

• Blɔd vesel dɛn kin wik ɛn strɛch, lɛk ol rɔba tiub. Dis kin mek di blɔd vesel dɛn bulbul lɛk balyɔn, ɛn dis kin mek wi kɔl aneurisms .
• Di wɔl dɛn na di blɔd vesel dɛn kin tan ɛn bɔs, ɛn dis kin mek blɔd lik insay di tisu dɛn we de rawnd am.
• Blɔd vesel dɛn kin smɔl ɔ ivin blok ɔl . If dis apin, di ɔgan we de tek blɔd frɔm da blɔd vesel de nɔ go gɛt ɔksijɛn ɛn tin dɛn we go mek i gɛt tin fɔ it ɛn i go pwɛl.

Di tin we impɔtant pas ɔl na dat we di blɔd vesel dɛn pwɛl dis kayn we, di wok we di ɔgan dɛn we dɔn pwɛl kin mek i nɔ wok igen ɔ i kin lɔs igen.

Us ɔgan dɛn we PAN kin afɛkt mɔ?

Di ɔgan dɛm we go mɔs afɛkt pan polyarthritis nodosa na:

• Kidni dɛn
• Jɔnkshɔn
• Nεv dεm (we de kכntro di sεns εn di wok we wi limb dεm de du) .
• Alimentary tract (lɛk intestinal) .
• Kanda
• Mɔsul dɛn

Bɔrku tɛm, pɔrsin wae gɛt PAN go gɛt sɔm kayn sik na mɔr pas wan eria. Bɔt, na smɔl tɛm nɔmɔ, sɔm pipul dɛn kin gɛt di sayn dɛn nɔmɔ na dɛn skin (cutaneous PAN). Ivin da tɛm de, dɔktɔ dɛn go kɔntinyu fɔ wach yu fɔ si if ɔda pat dɛn gɛt di sik.

Di gud nyus na dat, polyarthritis nodosa nɔr kin gɛt sɔm kayn sik na di lɔng.

Aw i nɔ kin izi fɔ gɛt polyarthritis nodosa (PAN)?

Dis na rili tinNa sik we nɔ kin bɔku. Jɔs tink bɔt, pan wan milyɔn pipul dɛn na Amɛrika, nɔto tɛn pipul dɛn kin gɛt dis sik ɛvri ia. Na di sem tin de apin na Ingland. So yu kin imajin aw dis nɔ kin apin so ɔltɛm.

Us sayn dɛm wae yu kin si pan dis sik?

Bikɔs PAN kin afɛkt difrɛn pat dɛn na di bɔdi, di sayn dɛn kin difrɛn bad bad wan. Sɔm sayn wae kin kam pan pɔrsin wae gɛt dis sik na:

• Fɔ fil lɛk se i nɔ fayn: Na jɔs fɔ fil se sɔntin nɔ rayt.
• Taya: Nɔto jɔs taya, bɔt yu kin fil se yu nɔ gɛt ɔl yu trɛnk. Ivin we yu wek na mɔnin, yu kin fil lɛk se yu nɔ gɛt ɛni ɛnaji we lɛf.
• Nayt swet: I de swet bɔku we yu de slip.
• Fiva: Na fiva we kin kam pan pɔsin we nɔ gɛt rizin.
• Nɔr kin want fɔ it ɛn nɔr kin gɛt bɔku bɔku bɔdi: Yu nɔ kin fil lɛk fɔ it, so yu kin lɔs yu wet.
• Mɔsul ɛn/ɔ joyn pen: Sɔntɛnde, di fiva kin kam wit joyn pen, we kin fil lɛk wan lump na di bɔdi. I kin ivin so bad dat yu nɔ kin ivin ebul fɔ waka fayn.
• Ɛd at: Dis nɔ kin apin to ɔlman, bɔt i kin apin to sɔm pipul dɛn.
• Skin lɛsin: Sɔntɛnde dɛn kin tan lɛk tranga, pen bɔmp na di skin, ɔ i kin tan lɛk ɔlsa bak.
• Bɛlɛ pen: Yu kin gɛt bɛlɛ pen wantɛm wantɛm, ɛn sɔntɛnde yu kin gɛt nɔys.
• Blɔd na di stɔl ɔ yu urine: Dis na siriɔs sayn ɛn yu fɔ go to dɔktɔ wantɛm wantɛm.
• Shot we yu de blo.
• Chɛst de pen.
• Di ay blɔd prɛshɔn.
• Testiles we de pen: Man kin gɛt dis sayn.
• Nɔs ɛn vɔmit.
• Di an ɔ di leg dɛn kin swɛla ɔ nɔ gɛt trɛnk igen: Dis kin apin if di nerv dɛn afɛkt.

If yu gɛt wan ɔ mɔ pan dɛn sik ya, i go fayn fɔ mek yu nɔ fred ɛn go to dɔktɔ.

Wetin kin mek pɔsin gɛt polyarthritis nodosa (PAN)?

Fɔ tɔk tru, di wan dɛn we sabi bɔt mɛrɛsin stil nɔ no bɛtɛ bɛtɛ wan wetin kin mek pɔsin gɛt polyarthritis nodosa. Dɛn kin tink se i kin gɛt fɔ du wit wan jenɛtik prɛdispɔzishɔn (dat na sɔntin we de rɔn na famili) ɔ difrɛn blɔd dizayd.

Bɔt, risach dɔn sho se yu imyun sistɛmI de ple big pat pan dis. Wi imyun sistɛm rili tan lɛk ami we de protɛkt wi bɔdi frɔm sik dɛn. Bɔt sɔntɛnde, dis ami kin mistek bigin fɔ atak in yon sɛl dɛn. Semweso, insay PAN, di imyun sistɛm kin pwɛl in yon blɔd vesel ɛn tisu dɛn, we kin mek i swel.

Wan ɔda tin na dat dɛn dɔn si se di epataytis B vayrɔs infεkshɔn (ɛn sɔmtɛm na epataytis C infεkshɔn) kin bi di kɔz fɔ dis kכndyushכn. Na gud tin fɔ no se frɔm we dɛn bigin fɔ yuz di epataytis B vaysin, di nɔmba fɔ di ripɔt bɔt dis PAN sik dɔn go dɔŋ bad bad wan.

Udat dɛn kin gɛt dis sik? (Di tin dɛn we kin mek pɔsin gɛt prɔblɛm)

Bɔku tin dɛn de we kin mek pɔsin gɛt polyarthritis nodosa:

• Man dɛn kin gɛt dis sik pas uman dɛn.
• Pipul wae de bitwin 45 ɛn 65 ia kin gɛt bɔrku risk bak.
• Fɔ pipul dɛn we gɛt Epatitis B infɛkshɔn .

Wetin na di prɔblɛm dɛn we pɔsin kin gɛt we i gɛt PAN?

If dɛn nɔ trit dis sik fayn, sɔm siriɔs prɔblɛm dɛn kin apin. Dɛn tin ya na:

• Aneurysm , we na di blɔd vesel dɛn we kin mek di blɔd vesel dɛn we de go na yu liva ɛn kidni wik, kin apin. Dɛn tin ya kin mek pɔsin in layf de pan denja if dɛn bɔs.
• di bכdi kכlכt kin fכm insay di bכdi vεsul dεm (dis nכ kin bכku).
• di tisu dεm we de pwεl de apin bikoz di כksijεn εn nyutriεnt dεm nכ de.
• Gangrene na wan sik we di tisu dɛn kin day.
• At nɔ de wok fayn (dis bak nɔr kin kɔmɔn).
• Kidni fεil (dis tu nכ kin kכmכn).

Na dat mek i impɔtant fɔ go to dɔktɔ jɔs lɛk aw di sik dɔn sho.

Aw dɛn kin no se pɔsin gɛt polyarthritis nodosa (PAN)?

Dɔktɔ kin yuz bɔku tin dɛn fɔ no if pɔsin gɛt polyarthritis nodosa:

• Yu mεdikal histri: Tin dεm lεk sik dεm wae yu bin dɔn gɛt bifo, ilɛksɛf ɛnibɔdi na yu famili dɔn gɛt dis kayn sik.
• Fɔ ɛgzamin yu bɔdi: Di ​​dɔktɔ go chɛk yu fɔ si us ɔgan dɛn gɛt di sik ɛn if yu gɛt ɔda sik dɛn we gɛt di sem sayn dɛn.
• Blɔd tɛst dɛn.
• Speshal tɛst dɛn fɔ tek imej.

Wetin na di tɛst dɛn we dɛn kin du fɔ no if pɔsin gɛt sik?

Di dɔktɔ kin ɔda fɔ du tɛst dɛn lɛk dɛn wan ya:

• Blɔd tɛst ɛn urine tɛst: Dɛn tin ya kin gi sɔm aidia bɔt if inflamɛns de na di bɔdi ɔ if ɛni ɔgan dɔn afɛkt.
• X-ray we dɛn kin du.
• CT Angiogram (Computed Tomography - CT angiogram): dis kin εp fכ bεtεh fכ ases di kכndishכn fכ di bכdi vεsul dεm.
• MRA Scan (Magnetic Resonance Angiogram - MRA scans): Dis na ɔda we fɔ chɛk di blɔd vesel dɛn.
• Bayopsi: If ɔda tɛst dɛn sho ɛnitin we nɔmal, dɛn kin tek wan smɔl pat pan di tisu we afɛkt ɛn chɛk am ɔnda maykroskɔp. Dis na wetin go kɔnfyus di diagnosis fɔ vasculitis.

Aw dɛn kin trit polyarthritis nodosa (PAN)?

Di men tritmɛnt fɔ polyarthritis nodosa na di mɛrɛsin dɛn we de mek yu bɔdi nɔ ebul fɔ fɛt di sik, we de mek yu imyun sistɛm nɔ wok fayn .

Di men gol fɔ tritmɛnt na fɔ ridyus di inflamɛns na di blɔd vesel dɛm. We dis inflamɛns dɔn dɔn ɛn di sik dɔn ɔnda kɔntrol, dɔktɔ dɛn kin se yu de na "rɛmishɔn," we min se di sik dɔn wɛl. As yu sik de go bifo, yu kin ridyus di doz fɔ di mɛrɛsin smɔl smɔl ɛn leta yu kin stɔp am.

Di kayn drɔgs dɛn we dɛn kin yuz

If PAN dɔn afɛkt yu men ɔgan sistɛm dɛn (fɔ ɛgzampul, kidni, at, nervɔs sistɛm), yu kin nid fɔ yuz mɔ pas wan kayn mɛrɛsin. Di tritmɛnt dɛn we dɛn kin gɛt kin bi:

• Dɛn kin gi kɔtikosterɔyd mɛrɛsin lɛk prɛdnisɔn ɔ prɛdnisolon . Dɛn tin ya kin ridyus di swɛlin kwik kwik wan.
• Na di sem tɛm, dɛn kin gi ɔda mɛrɛsin we de mek di bɔdi nɔ gɛt bɛtɛ wɛlbɔdi, lɛk sayklofosfamid .

Dɛn kin gi pipul dɛn we gɛt sɔm kayn kansa bɔku bɔku sayklofosfamid. Bɔt dɛn kin gi pipul dɛn we gɛt vaskulaytis di doz we 10 to 100 tɛm smɔl pas di doz we dɛn kin gi fɔ kansa. Fɔ pipul dɛm wae gɛt polyarthritis nodosa, dis mɛrɛsin de woke bay wae i de slo di imyun sistɛm ɛn stɔp am fɔ mek i nɔr gɛt inflamɛns.

Dɛn kin yuse sayklɔfosfamid te di sik go na di rɛmishɔn, we na lɛk tri to siks mɔnt. Afta dat, dɛn kin chenj yu to ɔda immunosuppressant, lɛk methotrexate ɔ azathioprine, fɔ mek di sik nɔ kam bak (maintenance).

Di lɔng tɛm we yu nid fɔ tek dis mentenɛns imyunosuprɛsiv mɛrɛsin kin difrɛn frɔm wan pɔsin to ɔda pɔsin. Bɔku pipul dɛn nid fɔ tek dis mɛrɛsin fɔ at le wan ɔ tu ia, afta dat yu dɔktɔ go stɔp di mɛrɛsin smɔl smɔl ɛn disayd fɔ stɔp.

Bɔt nɔto ɔltɛm, if yu PAN kɔndishɔn nɔ afɛkt yu nervɔs sistɛm, at, kidni, ɔ intestinal, pipul dɛn de we kin bɛnifit frɔm kɔtikosterɔyd mɛrɛsin nɔmɔ.

Trit epataytis pan pipul dɛm we gɛt vaskulaytis kɔndishɔn lɛk PAN we gɛt fɔ du wit epataytis B infɛkshɔn.Dɛn kin gi am bak antivayrɔs mɛrɛsin .

Lɛ wi no bak bɔt di bad tin dɛn we di tritmɛnt dɛn kin du.

Dɛn mɛrɛsin ya we de mek pɔsin nɔ ebul fɔ fɛt di sik kin mek sɔm bad bad tin dɛn apin. Fɔ ɛgzampul, di we aw pɔsin de fil kin chenj, i kin mek i gɛt infɛkshɔn mɔ ɛn mɔ, ɛn i kin swel. So, i rili impɔtant fɔ pe atɛnshɔn gud wan to dɛn sayd ɛfɛkt ya. Dɔn dɛn kin avɔyd ɔ ridyus dɛn. Sɔntɛnde, ivin if yu bin de gri fɔ tek di mɛrɛsin fɔs, di sayd ɛfɛkt dɛn kin apin as tɛm de go. Na dat mek i impɔtant fɔ kɔntinyu fɔ de ɔnda dɔktɔ. Sɔntɛnde, yu nid fɔ wɔri bɔt di bad tin dɛn we go apin to yu fɔ lɔng tɛm ivin afta yu dɔn stɔp di mɛrɛsin.

We yu tek mɛrɛsin dɛn we de stɔp yu imyun sistɛm, yu ebul fɔ fɛt di infɛkshɔn dɛn kin ridyus smɔl. So, fɔ gɛt vaysin fɔ protɛkt yu frɔm infɛkshɔn lɛk flu ɔ nyumonia kin bi big ɛp.

Wetin yu kin ɛkspɛkt we yu de liv wit PAN stetɔs?

Fɔ sɔm pipul dɛm, polyarthritis nodosa kin kam sloslo. Fɔ ɔda pipul dɛn, i kin tranga kwik kwik wan ɛn ivin put dɛn layf pan denja insay sɔm mɔnt. Na mɔtalman, di wan dɛn we gɛt simptom fɔ di dijestiv sistɛm, at, kidni, ɛn/ɔ sɛntral nervɔs sistɛm kin gɛt bad bad tin fɔ si pas di wan dɛn we nɔ gɛt am.

Bɔt pan ɔl we polyarthritis nodosa kin bi wan sik we kin kam wantɛm wantɛm, bɔku pipul dɛn we gɛt PAN kin wɛl fayn fayn wan . Aw yu kin wɛl kin dipen pan aw yu sik kin tranga. Bɔt ilɛk aw yu polyarthritis nodosa bad, if yu trit yu kwik kwik wan ɛn yu kin gɛt di sik we yu de kia fɔ yu, yu kin ebul fɔ gɛt di sik we dɛn kɔl remission.

Afta yu dɔn wɛl, di polyarthritis nodosa kin kam bak ɔ i kin kam bak . Di chans fɔ mek dis apin kin difrɛn frɔm 10% to 40%. De sayn dɛm wae de sho se pɔrsin gɛt dis sik bak kin bi di sem wae de wae dɛn bin fɔs no bɔt de sik, ɔr dɛn kin difrɛn. Di tritmɛnt fɔ pɔrsin wae gɛt dis sik bak na di sem wit fɔ pɔrsin wae jɔs gɛt dis sik. Bɔrku pipul dɛm wae gɛt polyarthritis nodosa kin wɛl.

Outlook fɔ PAN stetɔs

If yu gɛt tritmɛnt fɔ polyarthritis nodosa, yu gɛt at le 80% chans fɔ liv fɔ fayv ia. Bɔt if yu nɔr gɛt tritmɛnt, yu chans fɔ liv fɔ fayv ia kin go dɔŋ to less dan 15% . Dis de sho aw tritmɛnt impɔtant, nɔto so?

Yu tink se dɛn kin ebul fɔ protɛkt di sik we dɛn kɔl polyarthritis nodosa (PAN)?

Sɔm tin dɛn we kin mek pɔsin gɛt polyarthritis nodosa, lɛk di ej, nɔ kin chenj. Bɔt wan vaysin de we kin protɛkt pɔsin frɔm epataytis B, we kin mek sɔm pipul dɛn gɛt PAN. So, fɔ gɛt di vaysin kin ɛp fɔ protɛkt yu frɔm dis sik to sɔm mak.

Aw a fɔ kia fɔ misɛf? (Fɔ kia fɔ yusɛf) .

Bɔku tin dɛn de we yu kin du fɔ mek yu nɔ gɛt siriɔs sik bak:

• Notis yu dɔktɔ jɔs afta yu notis ɛni nyu sayn. Ilɛksɛf na jɔs smɔl tin, tɛl yu dɔktɔ .
• Si yu dɔktɔ di rayt tɛm (folɔ-ap apɔntinmɛnt). Mek shɔ se yu go fɔ chɛk di de dɛn we yu dɔktɔ se.
• Gɛt monitarin lab tɛst lɛk blɔd tɛst we dɛn du fayn fayn wan.

If yu du dɛn tin ya kɔrɛkt wan, yu kin wach aw yu sik ɛn bigin fɔ trit yu kwik kwik wan if nid de.

Ustɛm a fɔ go to dɔktɔ?

If yu tink se yu gɛt sɔm pan di sayn dɛm fɔ PAN, go to dɔktɔ fɔ advays. Bɔt if yu chɛst de pen ɛn i nɔ izi fɔ yu fɔ blo, go na imejensi rum wantɛm wantɛm. Nɔ put am bifo.

Us kwɛstyɔn dɛn a fɔ aks mi dɔktɔ?

I fayn fɔ aks yu dɔktɔ kwɛstyɔn dɛn lɛk dɛn wan ya:

• Us mɛrɛsin dɛn we bɛtɛ fɔ mi?
• Sɔpɔt grup de we go ɛp mi?
• Yu go ebul fɔ no wetin kin mek pɔsin gɛt dis sik?
• Aw lɔng a go gɛt fɔ tek di mɛrɛsin?

Fɔ bia wit di sayn dɛm fɔ polyarthritis nodosa ɛn di sayd ɛfɛkt dɛm wae mɛrɛsin kin gɛt kin tranga sɔmtɛm. If yu nid fɔ tɔk to pɔsin we ɔndastand wetin de apin to yu, nɔ fred fɔ go to pɔsin we de advays yu fɔ ɛp yu. Ɛn nɔ ɛva shem fɔ aks yu dɔktɔ bɔt ɛnitin we nɔ klia to yu.

Fɔ dɔn, mɛsej we yu kin kɛr go na os

Polyarthritis nodosa (PAN) na wan sik we nɔ kin bɔku bɔt we kin rili siriɔs. Bɔt, nɔ panik. De tin wae impɔtant pas ɔl na fɔ no bɔt dis sik, go to dɔktɔ kwik kwik wan wae yu gɛt dis sik, ɛn gɛt di rayt tritmɛnt.

Mɛmba se, if dɛn no di sik kwik kwik wan ɛn gɛt di rayt tritmɛnt, bɔku pipul dɛn we gɛt PAN dɔn ebul fɔ kɔntrol dɛn kɔndishɔn ɛn liv nɔmal layf. Nɔto yu wan de, ɛn dɔktɔ ɛn pipul dɛn de we de wok fɔ di wɛlbɔdi biznɛs we go ɛp yu.

Wi op se yu si se dis infɔmeshɔn go ɛp yu! Stay wit wɛlbɔdi!

` Polyarthritis nodosa, PAN, vasculitis, blɔd vesel inflameshɔn, imyun sistɛm, ɛpatitis B, kɔtikosterɔyd