Yu kin fil ɔltɛm se yu taya ɛn yu nɔ gɛt layf? Wan rizin fɔ dis kin bi bikɔs blɔd nɔ de na di bɔdi, we na wan sik we dɛn kɔl anemia insay mɛrɛsin. We dis anemia kin apin bikɔs ɔf sɔm mɛrɛsin, yu kin gɛt fɔ tek blɔd bɔku tɛm. So, tide wi go tɔk bɔt wan nyu mɛrɛsin we dɛn dɔn kam wit na di wɔl fɔ trit dɛn kayn sik ya. Di nem fɔ da drɔg de na Reblozyl.
Us kayn mɛrɛsin na Reblozyl?
Reblozyl na dכg we dεn bin apruv insay 2019. fכ bi prεsis, i de pan wan klas dεm we dεn kכl ``erythroid maturation agents (EMA)''. Okay, okay, dat wod kin saund likli komplikayt. Fɔ tɔk am simpul wan, dis drɔg de ɛp di rɛd blɔd sɛl dɛn we de mek na wi bon mɛro fɔ "machɔ", dat na fɔ bi sɛl dɛn we dɔn gro fayn ɛn we gɛt wɛlbɔdi. Dɛn kin yuz dis mɛrɛsin mɔ fɔ mɛn anemia we sɔm blɔd sik dɛn kin kam wit. Ɛspɛshali pan big pipul dɛn we gɛt dɛn tu sik ya: 1.
Beta-thalassemia: Pipul dɛn we nid fɔ gɛt blɔd ɔltɛm bikɔs ɔf dis sik. 2.
Myelodysplastic Syndromes (MDS): Dɛn kin kɔl dis bak bon
mɛro we nɔ de wok fayn. So, dɛn kin gi Reblozyl bak to pipul dɛn we nid fɔ gɛt blɔd ɔltɛm.
Lɛ wi lan smɔl mɔ bɔt beta-thalassemia ɛn MDS.
If yu ɔndastand smɔl bɔt dɛn tu sik ya, i go izi fɔ ɔndastand aw di Reblozyl drɔg de wok.
- Beta-thalassemia: Tink bɔt di rɛd blɔd sɛl dɛn we de na wi blɔd as motoka dɛn we de kɛr ɔksijɛn. Di ɔksijɛn we de insay dis motoka de lod pan wan prɔtin we dɛn kɔl ɛmoglobin . Pɔsin we gɛt beta-thalassemia nɔ de mek dis ɛmoglobin prɔtin we go du fɔ am. So di sɛl dɛn na di bɔdi nɔ kin gɛt di ɔksijɛn we dɛn nid. Na dat mek sɔm sayn dɛm lɛk fɔ taya ɔltɛm ɛn fɔ gɛt paleness kin apin.
- Myelodysplastic syndrome (MDS): Dis na wan kayn kansa we kin bigin na di bon mכro. di bon mכro na di fכktri we de mek wi bכdi sεl dεm (rεd sεl, wayt sεl, εn pletlεt). Insay pɔsin we gɛt MDS, di prodakshɔn fɔ dis faktri kin ambɔg. Dis min se di we aw dɛn kin mek blɔd sɛl dɛn we gɛt wɛlbɔdi ɛn we dɔn divɛlɔp fayn, nɔ kin bɔku.
Insay dɛn tu tin ya, di men prɔblɛm na we di nɔmba fɔ di rɛd blɔd sɛl dɛn we gɛt wɛlbɔdi ɛn we de wok fayn, de go dɔŋ, we min seAnemia kin apin.
Riblozyl de wok bay we i de ɛp di rɛd blɔd sɛl dɛn we nɔ machɔ we nɔ de gro fayn fɔ machɔ fayn fayn wan. Dis kin mek di rɛd blɔd sɛl dɛn we gɛt wɛlbɔdi, i kin mek di ɛmoglobin bɔku, ɛn i kin mek di bɔdi ebul fɔ kɛr ɔksijɛn fayn. Dis
kin mek yu nɔ nid fɔ tek blɔd ɔltɛm.
Bɔt mɛmba dis: Reblozyl nɔto tin fɔ tek ples fɔ blɔd transfyushɔn. Na jɔs tritmɛnt we de ɛp fɔ ridyus di nid.
Aw dɛn kin gi dis mɛrɛsin?
Reblozyl nɔto pil we yu kin tek na os. Na shot we dɛn kin gi
ɛvri 3 wik . Na dɔktɔ ɔ nɔs we tren na yu dɔktɔ in ɔfis, klinik, ɔ ɔspitul kin gi dis shot.
- Usay fɔ gi di vaysin: Dɛn kin gi dis vaysin ɔnda di skin na di an, di shɔl, ɔ di bɛlɛ, dɔŋ di sholda.
- Fɔ gɛt di vaysin di rayt tɛm: I rili impɔtant fɔ go tek di vaysin di sem de we di dɔktɔ gi yu. If yu mis di de, kɔl di dɔktɔ wantɛm wantɛm ɛn aks fɔ advays di nɛks de we go kam.
- Wan dayari fɔ simptom: I fayn fɔ rayt yu simptom (lɛk taya ɛn diziz ) na notbuk ɔ na yu fon ɛvride. Dis go mek am izi fɔ ɛksplen to yu dɔktɔ aw di mɛrɛsin de afɛkt yu.
Di doz fɔ di mɛrɛsin we dɛn go gi yu na yu dɔktɔ go disayd bay yu wet ɛn aw yu bɔdi de ansa di mɛrɛsin.
Wetin na di bad tin dɛn we kin apin to pɔsin? Aw fɔ dil wit dɛn?
Lɛk ɛni mɛrɛsin, Reblozyl kin mek sɔm sayd ɛfɛkt. Nɔto ɔlman kin gɛt dɛn, bɔt i impɔtant fɔ no bɔt dɛn. Di tebul we de dɔŋ ya de sho sɔm pan di sayd ɛfɛkt dɛm we kin apin ɛn aw fɔ mɛn dɛn.
| Sayd Ifɛkt we i kin gɛt | Aw fɔ manej am |
|---|
| Taya pasmak, diziz, nɔ ebul fɔ kɔntrol di bɔdi | Nɔ drayv ɔ yuz ebi ebi mashin te yu no gud gud wan aw dis mɛrɛsin de afɛkt yu. |
| Ed pen, mɔsul ɔ jɔyn pen | Aks yu dɔktɔ bɔt mɛrɛsin fɔ mɛn pen we go ɛp fɔ pul dɛn sik ya. Tɛl yu dɔktɔ if yu sik nɔr de bɛtɛ ɔr de wɔs. |
| Nɔs, bɛlɛ pen, dayarɛa (flatulence) . | Tray fɔ it smɔl smɔl tin dɛn pas fɔ it big it dɛn. It tin dɛn we nɔ fayn lɛk bred, krak krak, ɛn rays. Drink bɔku wata. If dɛn sik ya wɔs ɔ nɔr bɛtɛ, tɛl yu dɔktɔ. |
| Ay Blɔd Prɛshɔn | I impɔtant fɔ du ɛksɛsayz ɛn adopt wɛlbɔdi it lɛk DASH. Chek yu blɔd prɛshɔn ɔltɛm. If yu blɔd prɛshɔn pas 180/120 mmHg, go to di Imejɛnsi Dipatmɛnt (ETU) wantɛm wantɛm. |
| I nɔ izi fɔ blo, Alɛji riakshɔn | Aks yu dɔktɔ bifo tɛm bɔt di sayn dɛm we de sho se yu gɛt alɛji (e.g., yu skin de rɔsh, yu de it, yu fes de swel, yu nɔ de blo fayn). If yu gɛt ɛni wan pan dɛn sik ya, kɔl yu dɔktɔ wantɛm wantɛm ɔ go na di Imejɛnsi Dipatmɛnt (ETU) we de nia yu . |
| Fluid we de gɛda na di bɔdi (ɛdima) . | If yu notis ɛni swɛlin na yu an, fut, ɔ bɔdi, tɛl yu dɔktɔ. Na in go gi dɛn di tritmɛnt we dɛn nid. |
Prɔblɛm kin de wit ɔda mɛrɛsin dɛn?
Yɛs. We yu tek Reblozyl, i kin mek yu gɛt prɔblɛm if yu tek sɔm ɔda mɛrɛsin dɛn. Mɔ if yu de tek ɔmon riplesmɛnt tɛrapi fɔ mɛnopauz ɔ bɔn kɔntrol pils, di risk fɔ mek yu blɔd klɔt kin bɔku.
So, mek shɔ se yu tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek, lɛk di wan dɛn we dɔktɔ gi yu, di mɛrɛsin dɛn we yu nɔ de bay, vaytamɛn dɛn, tradishɔnal mɛrɛsin dɛn, ɛn ɛbul prɔdak dɛn.
Mɛsej we dɛn kin kɛr go na os
- Reblozyl na wan nyu mɛrɛsin we dɛn kin gi as shot fɔ trit anemia we kin kam wit kɔndishɔn dɛn we dɛn kɔl beta-thalassemia ɛn MDS.
- Dis kin ɛp mɔ di rɛd blɔd sɛl dɛn we nɔ machɔ fɔ gro fayn fayn wan.
- Dis mɛrɛsin kin mek pipul dɛn nɔ nid fɔ tek blɔd ɔltɛm, bɔt i nɔ de tek blɔd in ples.
- Na dɔktɔ ɔ nɔs kin gi dis vaysin ɛvri 3 wik.
- Sɔm sayd ɛfɛkt lɛk ed we de at, taya, ɛn mɔsul pen kin apin. Tɔk to yu dɔktɔ bɔt ɛni sayn we nɔ kɔmɔn.
- I impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn we yu de tek.
Reblozyl, Anemia, Beta-Thalassemia, Maylodysplastic Syndromes, MDS, blɔd transfyushɔn, Luspatercept, ɛmoglobin
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