Lɛ wi lan mɔ bɔt Triptans fɔ maygren.

Yu dɔn ɛva gɛt ed we de at we yu kin fil lɛk se yu ed de kam fɔ bɔs, we jɔs de at na wan say? Yu kin fil bak fɔ vɔmit, yu nɔ kin ebul fɔ luk di layt, ɛn yu kin vɛks we yu yɛri sawnd? Dis na wetin wi kin kɔl maygren. Dis nɔto jɔs nɔmal ed we de at. Dis na wan sik wae gɛt fɔ du wit di bren. Fɔ sɔm pipul dɛn, dɛn nɔ kin ebul fɔ bia dis pen. Di wangren tin we dɛn kin du na fɔ sidɔm na dak, kwayɛt rum ɛn wet fɔ mek di pen dɔn. So if yu de sɔfa bak wit dis, i rili impɔtant fɔ mek yu no bɔt wan kayn mɛrɛsin we dɛn kɔl `Triptans`.

Wetin na Triptan dɛn?

Fɔ tɔk am simpul wan, `Triptans` na spɛshal kayn mɛrɛsin we dɛn kin gi fɔ mɛn maygren. Dis na di fɔs layn fɔ tritmɛnt fɔ maygren. Dɛn mɛrɛsin ya nɔ kin ebul fɔ mek maygren nɔ apin (eksept fɔ sɔm spɛshal kes dɛm), bɔt dɛn kin stɔp am wans i dɔn apin.

Dɛn drɔgs ya, we dɛn kɔl `Triptans`, dɛn bin fɛn am insay di 1980 dɛm ɛn dɛn bin rivɔlɔshɔn di tritmɛnt fɔ maygren. `Sumatriptan` na bin di fɔs drɔg we dɛn bin gri fɔ du dis. Bɔku ɔda `Triptan`s` dɛn bin introduks leta.

Aw triptan dɛn kin wok?

Fɔ ɔndastand dis, wi nid fɔ luk fɔs aw wi de fil pen. Di nerv dɛm na wi bɔdi nɔ de fil pen dairekt wan. Bifo dat, dɛn kin sɛn sayn to wi bren se sɔntin de na di bɔdi, lɛk we pɔsin wund ɔ infɛkshɔn. di bren de translet dεn signal dεm to wetin wi kכl "pen."

Sayɛnsman dɛn stil nɔ shɔ 100% aw maygren kin apin, bɔt dɛn biliv se tri men tin dɛn kin mek i apin:

1. Nyuron aktibכshכn: We maygrεn de, sכm nεv sεl dεm (nyuron) na di bren de aktibכt di we we nכ fayn. Dis na de tin wae kin mek pɔrsin fil pen ɛn ɔda sayn dɛm.

2. Blɔd sakulayshɔn chenj: We maygren apin, di blɔd vesel dɛn na di bren kin smɔl ɛn dilayt, we kin chenj di blɔd flɔ.

3. Inflammation: Dɛn kin tink bak se sɔm inflammatory kemikal dɛn na di bren kin mek pɔsin gɛt maygren.

Naw lɛ wi si aw `Triptans` de afɛkt dɛn prɔses ya. wi bren gεt wan `Nyurotransmitta` we dεn kכl `Serotonin`, we na kεmikכl mεsenja we de kכri mεsej bitwin nεv dεm. di dכg dεm `Triptans` de wok di sem we lεk dis `Serotonin`. dεn de tay to tri spεshal `rεsεpכta` tכp dεm na di bren. Tink bɔt dɛn `risɛptɔ` ya as ki fɔ lɔk, ɛn `Triptan` tan lɛk di ki dɛn we fit dɛn.

• 5HT1B rεsεpכta dεm: dεn ya de kכntro di wit fכ di bכdi vεsul dεm na di bren. di triptan dεm de mek dεn rεsεpכta dεm ya wok εn de εp fכ sכm di bכdi we dεn bכn we nכ nid fכ wayd we di maygrεn de.
• 5HT1D εn 5HT1F rεsεpכta dεm: dεn ya de ridyus di aktiviti fכ di nεv sεstem we de kכri pen signal to di bren. Dat min se dɛn kin stɔp di pen signal fɔ rich na di bren.

Dis na aw triptan kin kɔntrol maygren pen ɛn ɔda sayn dɛm.

Us kayn triptan dɛn de?

Sɛvin kayn triptan dɛn de we dɛn de yuz naw. Ɔl dɛn drɔgs ya kin dɔn na di "-triptan" pat pan dɛn nem, we kin mek i izi fɔ no dɛn. Yu dɔktɔ go disayd us kayn triptan go fayn fɔ yu.

Wetin na di bɛnifit dɛn we triptan dɛn gɛt?

Triptan na big blɛsin fɔ pipul dɛn we gɛt maygren fɔ sɔm rizin dɛn.

• Sɔm sayd ɛfɛkt dɛn: We yu kɔmpia am to di mɛrɛsin dɛn we dɛn bin de yuz fɔ mɛn maygren trade, di sayd ɛfɛkt dɛn we Triptans gɛt nɔ bɔku, ɛn dɛn nɔ kin rili bad.
• Nɔto adikshɔn: Pipul dɛn kin adikshɔn to pen kil, mɔ di opioid. Bɔt, triptan nɔ kin adikshɔn.
• Sef: In jɛnɛral, Triptan na wan klas we rili sef fɔ mɛrɛsin.
• I de insay difrɛn we dɛn: As yu si, dis mɛrɛsin nɔ jɔs de as pil, bɔt i de bak as sprɛy na yu nos ɛn injɛkshɔn. Dɛn kin yuz sprɛy ɔ injɛkshɔn fɔ pɔsin we nɔ kin izi fɔ swɛla pils ɔ vɔmit.

Sayd ɛfɛkt ɛn tin dɛn we yu fɔ no bɔt wit triptan

Lɛk ɛni mɛrɛsin, Triptan kin mek sɔm smɔl smɔl sayd ɛfɛkt dɛn. Bɔt nɔto ɔlman kin gɛt dɛn, ɛn if dɛn gɛt dɛn, bɔku tɛm dɛn nɔ kin siriɔs.

• Diziz we pɔsin kin gɛt
• Fɔ slip ɔ taya
• Fɔ mek yu flash
• Vɔmit
• Nek de pen
• We pɔsin de swet
• Di limb dɛn we de na di an ɛn fut dɛn kin swɛla
• Fɔ fil se yu wik
• Na smɔl tɛm nɔmɔ, yu kin fil pen na yu chɛst ɔ yu kin fil tayt.

Udat nɔ fɔ tek triptan?

Triptan nɔr fayn fɔ pipul dɛm wae gɛt sɔm kayn wɛl bɔdi prɔblɛm.

• Hat sik ɔr prɔblɛm wit yu blɔd sistɛm: If yu dɔn gɛt ɔ yu de pan denja fɔ gɛt at sik, ay blɔd prɛshɔn we yu nɔ ebul fɔ kɔntrol (unmanaged hypertension), strok, ɔ transient ischemic attack (TIA), yu dɔktɔ nɔ go tɛl yu fɔ tek dis mɛrɛsin.
• Prɔblɛm wit ɔda mɛrɛsin dɛn (Drug interactions):Triptan kin intarakt wit ɔda mɛrɛsin dɛm wae yu de tek, mɔr di wan dɛm wae gɛt ergotamine, wae dɛn kin yuse fɔ trit maygren. So mek shɔ se yu tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek, ivin di vaytamɛn dɛn .**
• Mama dɛn we gɛt bɛlɛ ɔ we de gi pikin in bɛlɛ: If yu gɛt bɛlɛ, yu de tray fɔ gɛt bɛlɛ, ɔ yu de gi pikin in bɛlɛ, yu fɔ rili tɔk to yu dɔktɔ bɔt aw fɔ yuz triptan.

Ustɛm yu fɔ go to dɔktɔ?

If di sayd ɛfɛkt dɛm fɔ triptan de ambɔg yu ɛvride aktiviti dɛm, ɔ if yu fil se yu mɛrɛsin nɔr de woke fayn lɛk aw i bin de woke, tɔk to yu dɔktɔ.

Ustɛm fɔ go to dɔktɔ kwik kwik wan:

Triptan nɔ kin gɛt siriɔs sayd ɛfɛkt. Bɔt if yu gɛt ɛni wan pan dɛn tin ya we tan lɛk at atak ɔ strok, go na ɔspitul in imejensi dipatmɛnt (ETU) wantɛm wantɛm.

• Bɔrku pen na yu chɛst ɔ tayt
• At bit we nɔ de bit ɔltɛm (fast, slow) .
• I nɔ kin izi fɔ yu fɔ blo
• Wan say na di bɔdi kin swɛla, wik, ɔ paralayz.

Sɔm pipul dɛm wae gɛt maygren kin gɛt sɔm kayn sik wae tan lɛk wae pɔrsin gɛt strok. Bɔt wi nɔ kin ebul fɔ no na os if na maygren simptom ɔ na strok. So , if yu gɛt dawt, di tin we sef fɔ du na fɔ go to dɔktɔ wantɛm wantɛm.