Yu kin fil se yu an ɛn yu fut dɛn kin fil lɛk se yu nɔ gɛt bɛtɛ trɛnk, yu kin wik, ɔ yu kin fil pen? Yu taya ivin we yu de waka fɔ shɔt tɛm? Dɛn tin ya kin bi sayn dɛm fɔ Kronik Inflammatory Demyelinating Polyneuropathy, ɔ CIDP fɔ shɔt tɛm. Wan nyu mɛrɛsin we dɛn dɔn mek we dɔktɔ dɛn de se fɔ ɛp dɛn sik pipul ya, dɛn kɔl am Vyvgart Hytrulo . So, tide wi go tɔk ditayli bɔt dis mɛrɛsin, aw i de wok, ɛn wetin yu nid fɔ no.
Wetin na CIDP? Aw Vyvgart Hytrulo de ɛp?
Fɔ tɔk am simpul wan, CIDP na ɔtoimyun sik. Dat min se wi bɔdi in difɛns sistɛm, we na di imyun sistɛm, kin mistek bigin fɔ atak wi yon nɛv dɛn. Imajin am lɛk se wi kɔntri in ami mistek atak wi yon pipul dɛn. Dis kin mek wi nerv dɛn pwɛl, ɛn dis kin mek wi gɛt sɔm sayn dɛn lɛk we wi mɔsul dɛn wik, wi nɔ kin fil fayn, ɛn wi kin fil pen.
So, aw dis mɛrɛsin we dɛn kɔl Vyvgart Hytrulo de ɛp wit dis? Tu men tin de insay dis mɛrɛsin. wan na wan protin we dεn kכl `efgartigimod alfa`. di כda wan na wan εnzym we dεn kכl `hyaluronidase`. Dis ɛnzaym de ɛp di bɔdi fɔ tek da prɔtin de fayn fayn wan.
di men wok we dis dכg de du na fכ biεn di nyu bכbi Fc rεsεpכta dεm (FcRn) na wi bכdi. we i de tay, i de ridyus di amoun fכ wan protin we dεn kכl ` Immunoglobulin G (IgG)` insay wi bכdi. dis IgG protin na in de pwεl wi nεv dεm bכku tεm. So, we di amoun fכ dis bad bad IgG dכn rεdכks, di damej pan di nεv dεm de rεdכks εn di wik we de go כp na yu limb dεm de kכntrכl.
I rili impɔtant fɔ bigin tritmɛnt fɔ CIDP kwik kwik wan, bikɔs di kwik we dɛn bigin fɔ trit, na di mɔ di chans fɔ mek yu wɛl ful wan.
Aw fɔ yuz Vyvgart Hytrulo?
Dɛn kin gi dis mɛrɛsin as injɛkshɔn we dɛn kin put ɔnda di bɔdi. Bɔku tɛm, dɛn kin gi am wan tɛm insay di wik. Na wɛlbɔdi biznɛs pɔsin kin gi am na ɔspitul, ɔ dɛn kin tich yu ɔ pɔsin we de kia fɔ yu aw fɔ gi yusɛf di injɛkshɔn na os.
Di tin we impɔtant pas ɔl na fɔ wach yu fɔ at le 30 minit afta di injɛkshɔn, bikɔs i kin gɛt alɛji .) Si if i kin apin. Nɔ mis ɛni wan pan yu dɔktɔ apɔntinmɛnt dɛn. If yu mis wan doz, yu kin tek am insay tri dez frɔm di de we dɛn dɔn plan fɔ tek am. Dɔn tek yu mɛrɛsin akɔdin to wetin yu kin du ɔltɛm.
Wetin na di sayd ɛfɛkt dɛm fɔ dis mɛrɛsin? Aw a go dil wit dɛn?
Lɛk ɛni mɛrɛsin, Vyvgart Hytrulo kin mek sɔm sayd ɛfɛkt. Bɔt, nɔto ɔlman kin gɛt dɛn. Lɛ wi luk di men wan dɛn ɛn wetin yu go du bɔt dɛn.
| Sayd Ifɛkt we i kin gɛt | Diskripshɔn ɛn manejmɛnt |
|---|---|
| Alɛji Riakshɔn dɛn | Skin rash, swel ɔnda di skin, ɛn i nɔ kin izi fɔ blo. Bɔku tɛm, dɛn tin ya nɔ kin siriɔs. Bɔt sɔntɛnde, dɛn kin tranga fɔ mek i nɔ izi fɔ blo. If yu gɛt ɛni wan pan dɛn sayn ya, tɛl yu dɔktɔ wantɛm wantɛm. |
| Riakshɔn dɛn we pɔsin kin du wit di infushɔn | Insay ɔ insay wan awa afta di injɛkshɔn, yu kin gɛt blɔd prɛshɔn, kol, ɛn pen na yu chɛst, bɛlɛ, ɔ bak. Yu dɔktɔ go wach dis ɛn trit am if nid de. |
| Riakshכn dεm na di sayt we dεn de injεkshכn | Rɛd, it, brus, ɛn pen na di say we dɛn injekt. Bɔku tɛm, dɛn tin ya nɔ kin siriɔs ɛn dɛn go dɔn insay wan ɔ tu dez. |
| Infεkshכn dεm | Yu kin gɛt kol, yu trot kin at, ɔ yu kin gɛt infekshɔn na yu urinary tract. If yu gɛt fiva, kɔf, ɔ yu bɔdi de at, drink bɔku wata ɛn rɛst. If yu gɛt infekshɔn lɛk dis, yu kin nid fɔ delay yu nɛks doz fɔ mɛrɛsin te i klia. Tɔk to yu dɔktɔ bɔt am. |
| Ed de at | Sɔm pipul dɛn kin gɛt ed pen, ivin maygren. We yu tɛl yu dɔktɔ bɔt dis, i go gi yu di rayt mɛrɛsin fɔ mek yu fil pen. |
Dis na de men sayd effekt wae yu kin get. Bɔt nɔto ɔlman go ɛkspiriɛns dɛn ɔl. If yu gɛt ɛni sayn we nɔ kɔmɔn ɔ we de mɔna yu, mek shɔ se yu tɔk to yu dɔktɔ bɔt am.
Wetin di risach bɔt dis mɛrɛsin se?
Di ADHERE trayal na di men klinik stɔdi fɔ invɛstigat di ɛfɛktiv ɛn sef fɔ dis drɔg. I bin luk aw di drɔg bin wok fayn pan CIDP pasɛnt dɛn. I bin luk bak aw Vyvgart Hytrulo bin wok fayn we yu kɔmpia am wit wan plesibo.
Wetin na di men tin we dɔn kɔmɔt frɔm di risach?
Di impɔtant tin we dɛn fɛn na di ɛnd pan di stɔdi na dat di wan dɛn we tek Vyvgart Hytrulo bin gɛt 61% lɔwa risk fɔ mek dɛn gɛt di sik bak pas di wan dɛn we tek di plasɛbo. Fɔ tɔk am simpul wan, risach dɔn sho se dis mɛrɛsin de ɛp fɔ kɔntrol di sik ɛn ɛp yu fɔ de wɛl.
Bɔt mɛmba se dɛn tin ya na tin dɛn we dɛn dɔn du we dɛn dɔn du risach. Di tin dɛn we yu kin du kin difrɛn. I kin difrɛn frɔm wan pɔsin to ɔda pɔsin. So, di dɔktɔ we de trit yu go ɔndastand yu sik fayn fayn wan.
Mɛsej we dɛn kin kɛr go na os
- Vyvgart Hytrulo na nyu mɛrɛsin we dɔktɔ gi fɔ di nyurolɔjik sik we dɛn kɔl CIDP.
- Dis na injεkshכn we dεn kin gi כnda di skin wan tεm insay di wik.
- dis de wok bay we i de ridyus di lεvεl fכ wan protin we dεn kכl IgG frכm di bכdi we de pwεl di nεv dεm.
- Sayd ɛfɛkt lɛk alɛji ɛn infɛkshɔn kin apin. Tɛl yu dɔktɔ wantɛm wantɛm bɔt ɛni ɔda sayn we nɔ kɔmɔn.
- Dis mɛrɛsin fɔ jɔs yuz ɔnda di advays we yu dɔktɔ gi yu. Nɔ ɛva chenj di doz ɔ stɔp fɔ tek di mɛrɛsin fɔ yusɛf.
- If yu gɛt siriɔs alɛji, lɛk fɔ mek yu nɔ ebul fɔ blo, go na di ɔspitul imejensi dipatmɛnt (ETU) we de nia yu wantɛm wantɛm.
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