Hnute cancer i vei tih hriat a nih chuan i doctor chuan cancer cell chungchang hriat belh nan test eng emaw zat a ti ang. Hei hi cancer tissue thenkhat surgery emaw biopsy emaw hmanga lak a ni tlangpui. Heng test zinga pakhat chu cancer cell-te hian ' hormone receptor ' an nei em tih enfiah a ni. Heng receptor te hi cell chunglama ‘lock’ te tak te angin ngaihtuah rawh. Heng lock-a hormone an tih ‘key’ te hi an in fit chuan cell te hian thanglian turin thuchah an dawng thin.
Progesterone hi kan taksaah hian pianphung atanga lo chhuak hormone a ni. Hmeichhia puitlin hun, thlasik hun, leh naupai ang chi thil atan a pawimawh hle. Breast cancer cell thenkhat chuan an chung lamah receptor an nei a, chu chuan he hormone hi a inzawm thei a ni. Hetiang cancer chi hi progesterone-receptor positive, a nih loh leh PR-positive (PR+) hnute cancer tih mai a ni. Hetiang a nih chuan hormone progesterone a lo kal a, cancer cell te chu a inzawm a, an lo thanglian zel theih nan a pui a ni. Chuvangin, hei hi enkawlna te hian he hormone process hi tihtawp an tum thin.
Chutiang bawka hnathawk hormone dang chu estrogen a ni. Cancer cell-te hian estrogen receptor an neih chuan estrogen-receptor positive, emaw ER-positive (ER+) cancer an ti a ni.
Hetiang dinhmun hi tute nge hlauhawm zawk?
I cancer cells te hi PR-positive, ER-positive emaw, a pahnih emaw a nih chuan hormone-receptor positive (HR+) hnute cancer an ti tlangpui. Vanneihthlak takin hnute cancer hmuhchhuah 10 zinga 7 vel chauh hi hetiang chi hi an ni. Hetiang cancer chi hi kum eng pawhah a awm thei a, mahse hmeichhia, menopause paltlang tawhte zingah a tam zawk.
A tlangpuiin, hnute cancer eng pawh tichhe thei risk factors ang chiah hian HR-positive cancer pawh a nghawng ve bawk. Eng nge an nih i han thlir teh ang.
| Risk factor a ni | A awlsam zawngin... |
|---|---|
| Hmeichhia nih hi | Hmeichhia hi mipa nena khaikhin chuan an hlauhawm zawk. |
| Kum upa lam | Kum upat rualin a hlauhawmna a sang chho zel. |
| Hnute cell-a thil dik lo awm | Tun hmain hnute chhunga cell than dan pangngai lo (e.g. LCIS ) i neih tawh chuan. |
| Chhungkaw chanchin | Chhungkaw hnai tak pakhatin hnute cancer a vei tawh a nih chuan. |
| Puitling hma lam | Kum 12 a tlin hmain thlasik hun hi a intan thin. |
| Fa neih tlai | Kum 35 hnua i fa hmasa ber neih emaw, naupai ngai loh emaw. |
| Menopause tlai tak a ni | Kum 55 hnuah menopause. |
| Hormone therapy ei thin a ni | Menopause hnua hormone thlak danglamna therapy ei. |
Eng nge a lan chhuah dan?
A tam zawkah chuan hmeichhe tam zawk hian hnute cancer an vei tih hmuhchhuah an nih hian symptom an nei lo. Chu ai chuan routine mammogram neih laiin accident-in hmuhchhuah a ni zawk.
HR-positive breast cancer symptoms hi hnute cancer chi dang nen a inang vek a ni . Heng a lan chhuah dan tlangpui thenkhat chu hetiang hi a ni.
| Symptom a ni | Hei hi uluk takin enkawl rawh. |
|---|---|
| A hnute chhungah lump thar a awm | Lump thar i hriat theih apiang, a na lo pawh nise. |
| Hnute a hring chhuak | A hnute pum emaw a then emaw a hring chhuak. |
| Hnute emaw hnute emaw na | Natna danglam tak, awm reng. |
| Vun a inthlak danglam thin | Vun pil, orange peel lang, vun thick, sen, emaw vun ro, scaly. |
| Nipple a inthlak thin | Nipple chu indented emaw discharge a awm emaw a ni. |
| Lymph node a lo hring chhuak | Armpit-ah emaw, kawr vel emaw, kut a man theih tur lumps. |
Engtin nge hormone therapy hi hman a nih?
I enkawlna tur ruahmanna i siam hunah i doctor chuan i cancer hormone dinhmun a ngaihtuah ngei ang. PR-positive cancer enkawlna ber leh pawimawh ber chu hormone therapy a ni. A tum ber chu cancer cell-te’n hormone an hman theih lohna tura ven a ni.
A awlsam zawngin, hormone therapy hian cancer mamawh ‘chaw’ (hormone) supply a titawp a ni.
Hei hi kawng lian pahnih hmanga tih theih a ni:
- Surgical removal of the ovaries : Hei hian taksaa hormone siamchhuahna a ti tlem a ni.
- Hormone therapy pills emaw injection emaw: Heng damdawi te hian taksain hormone a siam chhuah loh nan a veng emaw, cancer cell-a receptor (locks) te a block a, hormone (key) nena inzawmna nei lo turin a veng bawk.
Hormone therapy i dawn chi pawh hi menopause i paltlang tawh leh paltlang lohah a innghat ang. He enkawlna hi cancer stage eng pawhah hman theih a ni. Cancer stage a zirin hormone therapy hi enkawlna dang, surgery emaw chemotherapy emaw te nen pek thin a ni.
Enkawlna dang engte nge ni?
Hormone therapy bakah hian PR-positive breast cancer tan a hnuaia mi pakhat emaw a aia tam emaw pek i ni thei bawk .
- Surgery: Cancer cells lakchhuahna tur surgery. Entirnan, lump chauh lakchhuah (`Lumpectomy`) emaw, hnute pumpui lakchhuah (`Mastectomy`).
- Chemotherapy: Cancer cell tihchhiatna atana damdawi chak tak pek.
- Radiation therapy : Cancer cell la awm zawng zawng tihchhiat nan high-energy rays a hmang.
- Targeted Therapy: Cancer cells te tihpunna tura puitu protein bik target tu damdawi. Hengte hian hormone hmanga enkawlna te pawh a tipung thei bawk.
Prognosis chu eng nge ni?
Hetah hian thu lawmawm tak tak i tan a awm e. Hormone-receptor-positive (HR+) cancer hi hormone-receptor-negative (HR-Negative) cancer aiin a thang zawi zawk thin . Tin, enkawlnaah pawh advantage i nei a, a chhan chu hormone hnathawh a tikhawlo thei a, cancer a tipung thei bawk. Mahse, cancer dang ang bawkin, nakin lawka tihdamna chu a hriat hma danah a innghat a ni.
Mahse, hriat reng tur a awm. Hormone therapy hian cancer than leh darh dan a control theih laiin, a chang chuan enkawl hnu kum tam takah a thleng thei bawk. Hei vang hian doctor-te chuan a chang chuan hormone therapy hi hun rei zawk an pe a, a chang chuan kum 5 emaw kum 10 emaw an pe thin.
Chuvangin, i cancer hormone receptor dinhmun leh i enkawlna tur ruahmanna leh hmalam panna kawng a nghawng dan tur chungchang hi doctor nen zalen tak leh chiang taka inbiakna neih a pawimawh hle.
Take-Home Thuchah a ni
- PR-Positive (PR+) hnute cancer tih awmzia chu cancer cell te hian hormone progesterone hmangin an thang lian tihna a ni.
- Hetiang cancer hi a tam hle a, a bik takin menopause hnuah a awm fo thin.
- Chumi atan chuan hormone therapy hi hmanraw tangkai tak leh hmanraw ber a ni.
- Heng cancer te hi a tlangpuiin prognosis hi a tha a, a chhan chu an thang zawi zawi a, mahse a lo lang leh tur ven nan hun rei tak enkawl leh medical check-up neih fo a ngai a ni.
- I dinhmun, i enkawl dan leh i ngaihtuahna eng pawh i doctor hnenah sawi hreh ngai suh.
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