I ruhte pawh a chak lo em ni? Fibrous Dysplasia chungchang hi han sawi ila!

Kan ruhte hi a chang chuan a chak lo thei a, kawng mak takin a lo thanglian thei tih i ngaihtuah ngai em? Vawiin hian ruh natna pakhat, hriat tlem deuh, mahse hriat tur pawimawh tak chungchang kan sawi dawn a ni. A hming chu Fibrous Dysplasia tih a ni. Hetiang dinhmun hi symptoms awm lovin i nei thei bawk. Chuvangin chipchiar deuhin sawi ila, kan sawi dawn em ni?

Fibrous Dysplasia hi eng nge ni?

A awlsam zawngin sawi ila, fibrous dysplasia hi kan taksaah hian ruh hrisel ni lovin fibrous (scar ang chi) tissue pangngai lo a lo thang lian zawk thin. He tissue thar hi ruh tak tak angin a chak lo. As a result , ruh te chu a chak lo va, a chhe (fracture) duh zawk.

Hetiang dinhmun hian taksa ruh eng pawh a nghawng thei a, mahse a nghawng tam ber chu:

• Thigh bone (kan ke chunglam ruh lian ber - `femur`) thlengin .
• To the shin bone (ke ruh hnuai lam ruh - `tibia`) .
• Ribs thlengin
• Luruh (hmai ruh te pawh tel) .
• A kut chunglam ruh (humerus) .

Thu lawmawm tak chu hei hi cancer (benign) a ni lo . Chu chu taksa ruh dangah a darh dawn lo tihna a ni. Chu chu a thlamuanna deuh a ni lawm ni?

Fibrous dysplasia chi hrang hrang a awm em?

Ni e, doctor-te chuan he natna hi chi hnih-ah an ṭhen a, chu chu ruh natna vei zat a zirin a ni:

1. Monostotic fibrous dysplasia: Hei hian ruh pakhat chauh a nghawng.

2. Polyostotic fibrous dysplasia: Hei hian ruh engemaw zat a nghawng .

A châng chuan, ``McCune-Albright syndrome`` tih hming pu natna hlauhawm tak i neih chuan polyostotic fibrous dysplasia i nei thei bawk. He syndrome hian kan ruh, vun, leh ``endocrine system`` (hormone control tu system) te a nghawng a ni.

Hei hi eng symptoms nge ni?

Fibrous dysplasia vei zawng zawng hian symptom an nei vek lo. Chuvang chuan ngaihtuah harsa deuh a ni. Mi thenkhat chuan chhan dang avanga X-ray an neih hian accident-in an nei tih an hrechhuak thin.

Mahse, symptom nei ve tho tan chuan a hnuaia mi hi a thleng thei a ni:

• Ruh tliak fo: Tlu tenau pawhin ruh a tikehsawm thei.
• Ruh na: Ruh natnaah hian natna nasa tak i nei thei. He natna hi zawi zawiin a pung thei a, a chang chuan a na hle bawk.
• Ruh pianzia inthlak danglam: Ruh chu a hring emaw, a lo thang danglam emaw angin a lang thei.
• Rib-a natna awm lo: Mi thenkhat chuan ruh area-ah lump ang maia hring an nei a, mahse a na lo.
• Scoliosis: Spine hi a sir khatah a inher thei.
• Mit chhuak chhuak:Luruh ruhte a nghawng chuan mit chu hmalam pan angin a lang thei.
• Jaw twitching: Jaw ruh a nghawng chuan jaw chu a sir khatah a twitch thei.
• Ha inher emaw, a inrem lo emaw: Ha ruh inthlak danglam vangin ha a inthlak emaw, a inzawm tha lo emaw a ni thei.
• Nasal congestion: Hmai ruh a nghawng chuan hnar congestion reng reng i nei thei.

A tlangpuiin ruh tam tak natna nei (polyostotic) te hian ruh pakhat chauh natna nei (monostotic) te aiin harsatna an nei tam zawk.

Engvangin nge fibrous dysplasia hi a lo awm?

Hei hi a buaithlak deuh a ni. Hetiang dinhmun hi nausen pum chhunga kan naupai hnua kan taksaa gene pakhat `GNAS1` tih random mutation avanga lo awm a ni. He genetic mutation hian kan cell `osteoblasts` an tih te a nghawng a ni. Osteoblasts hi cell chi khat bik a ni a, kan ruh te hi a lo thang lian a, a lo piang chhuak thin. Chuvangin, heng cell te hnathawh a tihbuai chuan fibrous tissue pangngai lo chu a lo piang ta a ni.

Pawimawh tak: Doctor-te chuan he genetic mutation hi engvangin nge a lo awm tih chiang takin an la hre lo. Tin, thlahtute pawh a ni lo. Chumi awmzia chu he natna hi nei mah la, i fate hian an rochun dawn lo tihna a ni. I sualna leh engmah a ni lo. Chuvangin ngaihtuah buai suh, okay?

Hei hian eng harsatna nge a thlen theih?

Fibrous dysplasia-a harsatna hmuh tur ber chu ruhte hi a chhe awlsam hle a, a chhan chu tissue siam thar hi ruh tak tak angin a chak lo.

Tin, he natna hian mit chhehvel ruh emaw, beng vel ruh emaw a nghawng chuan hriatna emaw, mitdel emaw a awm thei bawk. Chuvangin chutiang symptoms te pawh hi kan hriat chian a pawimawh hle.

Doctor-te hian engtin nge hei hi an hmuh?

Ruh na emaw, thil dang danglam bik emaw i neih chuan Doctor pan tur a ni. Doctor chuan i symptoms te, eng chen nge a awm tawh tih te a zawt hmasa ang che. Tichuan taksa enfiahna an nei ang a, a bik takin natna awmna hmun chu ngun takin an en ang.

Tin, test te pawh tih theih a ni bawk a, chungte chu:

• Thisen leh zun test: Heng test te hi enzyme level thenkhat a sang em tih hriat nan an ti thin. An sang a nih chuan hei hian fibrous tissue lo thang dan pangngai lo chungchangah clue a pe thei a ni.
• Imaging test hrang hrang:
• X-ray: Hengte hian tissue pangngai lo, ruh tliak leh ruh pianzia inthlak danglamna te a hmu thei a ni.
• CT scan leh MRI: Hengte hian X-ray aiin thlalak chiang zawk, chipchiar zawk a siam thei a ni. Ruh dinhmun ngun zawka zir chian nan an pui thin.
• Biopsy test hmanga enfiah: 1.1.A châng chuan, doctor-in rinhlelhna a neih chuan, chu tissue pangngai lo emaw, ruh hrisel emaw aṭanga a tê tê tak tê chu la in microscope hmangin an enfiah ang. Hei hi biopsy an ti a. Hei hian natna hi a nemnghet chiang hle.

Fibrous dysplasia hi engtin nge enkawl a nih?

Enkawl dan tur chu i natna lan chhuah dan, i natna nasat dan leh i nun a nghawng danah a innghat a ni. Mi zawng zawng hian enkawlna chi khat an mamawh vek lo.

Enkawl dan tlangpui chu hetiang hi a ni.

1. Enfiahna: I natna lanchhuahna i neih loh chuan, emaw, i natna lanchhuahna a nasat loh chuan i doctor chuan enkawlna bik a pe lo mai thei a, mahse i ruhte chu checkup mumal tak (follow-up appointment) hmangin a enfiah thei a ni. Hei hi inthlak danglamna a awm em tih en nan a ni.

2. Damdawi: Damdawi thenkhat (e.g. bisphosphonates) hi ruh tichak turin, ruh tliak hlauhawmna tihziaawm nan leh natna control nan te pek theih a ni.

3. Bracing: A chang chuan ruh chak lo zawkte thlawp turin braces vuah turin an ti thei che a, an thang tha thei ang bera tanpui turin leh deformities ven nan an ti thei bawk.

4. Surgery tih tur: 1.1 .

• Ruh chhe fo thinte chu tichak rawh.
• Ruh tliak na tak takte siamthat.
• Ruh pianzia a dik lo a nih chuan siamthat tur a ni.
• A châng chuan, ``bone grafts'' tih a ngai mai thei.Hei hian taksa peng dang aṭanga ruh hrisel tak tak la chhuakin, ruh natna hmunah dah luh tihna a ni.

Engtikah nge Doctor ka hmuh ang?

Ruh natna reh lo i neih chuan doctor pan ngei ngei tur a ni. Fibrous dysplasia vang a ni lo mai thei, mahse a chhan zawn a pawimawh.

Fibrous dysplasia i vei tih i hriat tawh chuan i doctor hnenah:

• I symptoms a zual zel ang tih i hriat chuan .
• I enkawlna te hian a pui lo nia i hriat chuan .

Pawimawh: Fibrous dysplasia hian ruh a tichak lo a, i tlu emaw, thil na tak i tawk emaw, car accident i tawk emaw a nih chuan damdawi in hnai ber emergency room-ah kal nghal rawh. A ruh tliak theihna a sang hle.

Fibrous dysplasia ka neih chuan eng nge ka beisei ang?

He zawhna hi chhanna pakhat chauh pek a harsa a, a chhan chu fibrous dysplasia hian mi zawng zawng a nghawng dan a inang lo. Mi thenkhat chu harsatna lian tham nei lovin an nung thei. Mi dangte chuan tlem tal fimkhur leh enkawl a ngai mai thei.

Mahse thil pakhat chiang tak chu fibrous dysplasia hi natna rei tak a ni.Chu chu natna tihdam theih vek a ni lo tihna a ni a, mahse i nunah nghawng a neih tlem theihna tura pui thei tur enkawlna a awm.

Hetiang dinhmun hi i nei tih i hriat chuan mak i ti a, tlem chuan i lungkham thei bawk. Chu chu thil pangngai a ni. Mahse, nangmah chauh i ni lo tih hre reng ang che. Hemi chungchang hi i doctor nen inhawng takin sawi rawh. Eng nge i beisei tur tih leh eng enkawlna nge i tana tha tur tih a hrilhfiah ang che.

A tawp berah chuan thil hriat reng tur (Take-Home Message) .

Okay, chuvangin vawiin a kan sawi fibrous dysplasia chungchang khaikhawmna atan heng point te hi i hre reng ang u:

• Fibrous dysplasia hi ruh natna hmuh tur awm lo tak a ni.
• In this , ruh hrisel ai chuan chak lo, fibrous tissue a lo awm ta a ni.
• Hei hian ruh a tikehsawm awlsam hle.
• Mi thenkhat chuan symptoms an nei lo mai thei .
• Hei hi cancer a ni lo va, rochun a ni lo bawk.
• Damdawi famkim awm lo mah se, natna lan chhuah dan thunun tur leh nunna a nghawng tihziaawmna tur enkawlna a awm.
• Ruh na emaw, rinhlelhna dang emaw i neih chuan doctor thurawn la ngei ang che.

He thu hi in tan a tangkai ngei ka beisei. Hemi chungchanga zawhna dang i neih chuan doctor zawt hreh suh. Hrisel takin awm rawh!

` Fibrous dysplasia, ruh natna, ruh tliak, ruh na, GNAS1 gene, ruh hriselna, natna hmuh tur awm lo