Damdawi ei chung pawhin i thisen sang chu a la thunun thei lo em ni? A chhan chu Hyperaldosteronism a ni mai thei!

Thisen sang , a nih loh leh kan hriat vek angin “ pressure ” i nei em? I doctor-in damdawi pakhat, pahnih emaw, a aia tam emaw i ei a ni mai thei. Mahse, damdawi tam tak i ei hnuah pawh i thisen sang thunun harsa i ti em? Chutiang a nih chuan, a chhan chu mi zawng zawngin kan ngaihtuah tlangpui a ni lo mai thei. Vawiin hian damdawi hmanga awlsam taka thunun theih loh thisen sang thlen thei damdawi lam dinhmun bik kan sawi dawn a ni. Chu chu Hyperaldosteronism a ni. A hming hi a buaithlak deuh a, mahse awlsam takin i hrethiam ang u.

Hyperaldosteronism hi eng nge ni?

A awlsam zawngin Hyperaldosteronism chu kan taksa chhunga adrenal glands ten hormone "Aldosterone" an siam tam lutuk hi a ni.

Tunah chuan i ngaihtuah mai thei, heng adrenal glands te hi eng nge ni ? He aldosterone hormone hi eng nge ni?

Ngaihtuah teh, kan taksa chhunga kal pahnih chungah hian gland te tak te pahnih a awm a, chu chu cap te te pahnih ang mai a ni. Chu chu adrenal glands kan tih chu a ni. Hengte hi kan endocrine system-a thil pawimawh tak a ni. Heng gland te pahnih hian kan taksa nitin hnathawhna atana pawimawh hormone chi hrang hrang an siam a.

Heng glands te hian hormone bik an siam chu aldosterone an ti a . He hormone hnathawh ber chu kan thisen sang tihreh hi a ni . Chu chu kan thisena sodium leh potassium awm zat control-in a ti a ni. He hormone hian kan taksaah hian traffic police officer-in kawngpuiah lirthei a control ang maiin hna a thawk a ni.

Chuvangin, Hyperaldosteronism chungchangah chuan thil thleng chu he aldosterone hormone hi a tam lutuk a ni. Tichuan kan taksaa sodium awm zat a pung a, potassium a tlem phah bawk. Chumi avanga a tawpah chuan thisen sang (Hypertension) leh thisena potassium level hniam (Hypokalemia) a ni.

Hei hi chi hnih lian tak a ni.

Doctor-te chuan he natna hi chi hnih lian takah an ṭhen a, a chhan a zirin.

1. Hyperaldosteronism hmasa ber: 1. A rilru a hah lutuk chuan a rilru a buai em em a.Hei hi "Conn's syndrome" an ti bawk. Hei hi adrenal glands-ah ngei pawh harsatna a awm vang a ni a, chu chuan hormone aldosterone a siam tam lutuk vang a ni. A chhan chu gland chhungah ngei a awm a ni.

2. Secondary Hyperaldosteronism: Hetah hian adrenal glands-ah harsatna a awm lo. Mahse taksa hmun dangah harsatna a awm avangin adrenal glands te chu an chhanna atan an tichak a, aldosterone an siam tam zawk thin.

He natna hian tute nge a nghawng tam ber?

He natna hian kum 30 leh 50 inkar mi a vei tlangpui a, zirchianna atanga a lan dan chuan he natna hi mipa aiin hmeichhiaah hian a tam zawk deuh hlek a ni.

Zirna thenkhatah chuan thisen sang nei zinga 5% leh 10% inkar chuan primary hyperaldosteronism an nei thei tih an sawi. Mithiamte chuan damdawi ei theih loh hypertension nei zinga 25% velin he natna hi an nei thei niin an ngai.

Hei hi eng symptoms nge ni?

A châng chuan, a natna hi a na lo hle a nih chuan, a lan chhuahna a awm lo thei bawk. Mahse, mi tam takin symptoms an nei thin.

Hetiang dinhmunah hian a lan chhuah dan ber leh langsar ber chu thisen sang (Hypertension) , a bik takin thisen sang, damdawi engemaw zat hman pawhin thunun harsa tak a ni.

Symptom dangte chu thil pahnih atanga lo chhuak a ni: Thisen sang leh thisen potassium level hniam (Hypokalemia). Heng symptoms te hi chiang takin i thliar hrang ang u.

Engvangin nge he Hyperaldosteronism hi a lo awm?

A hmaa kan sawi tawh ang khan a chhan hi chi lian pahnih a zirin a inang lo.

Primary Hyperaldosteronism awm chhan te

Hetah hian buaina chu adrenal gland ngeiah a awm a ni.

• A chhan tlangpui: A tam zawkah chuan hei hi cancer ni lo tumor (adrenal adenoma) adrenal gland-a lo awm vang a ni. Hei hi cancer a nih loh avangin lungkham tur a awm lo. He tumor hian hormone aldosterone a siam tam lutuk a.
• A chhan dang hmuh tur awm lo:
• Adrenal gland pakhat chauh a lian (unilateral adrenal hyperplasia).
• Cancer natna (adrenocortical carcinoma) (adrenocortical carcinoma) atanga aldosterone siam chhuah (hei hi a tlem hle).
• Genetic condition, thlah kal zel atanga lo awm thin (Familial hyperaldosteronism).

Secondary Hyperaldosteronism awm chhan te

Hetah hian adrenal glands te hi a hrisel hle. Mahse chhan dang vangin an stimulate a ni. A chhan ber chu kal (kidney) a thisen pek tlem vang a ni .

Chu chu hrethiam tur chuan kan taksaa thisen sang control tu system ngaihnawm tak mai hi tlem kan hriat a ngai a ni. A hming chu Renin-Angiotensin-Aldosterone System tih a ni.

Hei hi chain reaction angin han ngaihtuah teh:

1. Kan thisen sang a tlak hniam emaw, kan thisena sodium a tlakhniam emaw chuan kan kal (kidney) hian a hre thei.

2. Chumi hnuah kal (kidney) chuan thisenah enzyme "renin" an tih chu a chhuah tir a.

3. He renin hian protein pakhat "Angiotensinogen" tih chu liver atanga siam chu "Angiotensin I" ah a chantir thin.

4. A dawtah chuan he angiotensin I hi “Angiotensin II” a lo ni ta a ni.

5. A tawpah chuan he angiotensin II hian thisen kalna kawng a tikhawlo a, adrenal glands te chu aldosterone siam turin a tichak a, thisen sang a tisang a ni.

Tunah chuan secondary hyperaldosteronism-ah chuan thil thleng chu damdawi lam thil engemaw vangin thisen kal (kidney)-a kal zat a tlahniam a ni. Tichuan kal (kidney) te chuan taksaah pressure a hniam hle niin an ngai sual a . Chuvangin, kidney te hian tanpuina an ko a, chu chain reaction chu a intan ta a ni. Chuvang chuan hormone aldosterone chu an siam tam zawk a, chutih lai chuan a ngai tak tak lo.

Kidney-a thisen supply tihtlem leh secondary hyperaldosteronism thlentu dinhmun:

• Renal artery natna tikhawtlai thei.
• Taksa chhunga tui awmkhawmna hmun, heart failure ang chi te.
• Cirrhosis a awm thin.
• Nephrotic syndrome, kal natna a ni.

Engtin nge doctor hian he natna hi a hriat theih ang?

I doctor hnenah i natna lan chhuah dan, a bik takin thisen sang damdawi hmanga thunun theih loh i hrilh hian he natna hi a ringhlel mai thei. Tichuan, hei hi finfiah turin test eng emaw zat an ti thei ang.

1. Thisen test: 1.1.

• Routine electrolyte blood panel-ah sodium level sang deuh (Hypernatremia) leh potassium level hniam (Hypokalemia) a awm chuan rinhlelhna a pung thin.
• A dawtah chuan he natna hi hriat theihna tur thisen test bik pahnih a awm a, chungte chu: Plasma Renin Concentration (PRC) emaw Plasma Renin Activity (PRA) .
• Primary Hyperaldosteronism i neih chuan i renin level (PRC leh PRA) chu a pangngai aia hniam a ni ang.
• Secondary hyperaldosteronism i neih chuan i renin level chu a tlangpui aia sang a ni ang.

2. Aldosterone tihziaawmna test: 1.1.

• He test hian hun engemaw chen chhung sodium (salt) extra pek che a ni. Ka ei a solution emaw, vein-a saline solution i pek emaw pawh a ni thei.
• Tichuan, darkar 24 chhungin i zun chu an la khawm a, chu zun chhunga aldosterone awm zat chu an teh thin.
• Mi hrisel takah chuan sodium ei tam lutuk hian taksain aldosterone a siam chhuah a ti tlem a ni. Mahse, hyperaldosteronism nei miah chuan hetiang hi a thleng lo.

3. Imaging Test hrang hrang: 1.1.

• Thisen test-in primary hyperaldosteronism i nei tih a finfiah chuan i doctor chuan a chhan zawng turin CT scan (Computed Tomography scan) ang chi test a ti ang. Hei hian adrenal gland-ah tumor a awm leh awm loh a enfiah thei a ni.

Hei hi eng enkawlna nge ni?

Enkawlna chu a natna chhan a zirin a ni. Mahse, a tum ber chu i thisen sang control hi a ni.

• Tumor avanga primary hyperaldosteronism awm tan chuan:

Vawi tam tak chu doctor-te chuan tumor leh a kaihhnawih gland chu operation hmanga lakchhuah an rawt thin.. He surgery hnu hian mi tam zawk thisen sang leh potassium level chu a pangngaiin a kir leh thin. Amaherawhchu, mi thenkhat chuan zai an tih hnuah pawh thisen sang an nei chhunzawm zel thei a, damdawi an ei chhunzawm zel a ngai dawn a ni.

• A chhan dang leh secondary hyperaldosteronism atan chuan:

Heng hunah hian enkawlna chu damdawi hmanga enkawl a ni . Tin, secondary condition a nih chuan a hnuaia natna (e.g. heart disease) enkawl a pawimawh hle bawk.

Hemi atana damdawi hman tlanglawn tak tak thenkhat chu:

• A rilru a buai em em a, a rilru a hah em em bawk a.
• Eplerenone (Eplerenone – Inspra®) tih hi a tha hle.
• Amiloride (Amiloride – Midamor®) tih a ni a, a chhuahna hmun hi a nuam hle.

Enkawl hnuah eng nge thleng ang? Tin, eng harsatna nge a awm?

He dinhmun, chu chu nakin lawka a awm dan tur prognosis chu a chhanah a innghat a ni.

Primary hyperaldosteronism hi a hmaa hmuhchhuah a nih a, a \ha taka enkawl a nih chuan a tuar thei hle \hin . Secondary hyperaldosteronism-ah chuan a rah chhuah chu a hnuaia awm chu control theih a nih leh nih lohah a innghat a ni.

Hetiang dinhmuna harsatna awm thei ber chu hun rei tak chhung thisen sang control loh vang a ni. Hengte hi cardiovascular system nena inzawm harsatna lian tak tak an ni.

Chuvangin thisen sang hi uluk taka control a pawimawh hle.

Hetiang dinhmun hi ven theih a ni em?

A tam zawkah chuan he dinhmun hi lo awm lo turin kan tih theih tur a awm lo. A chhan chu kan taksa chhunga inthlak danglamna lo thleng vang a ni. Mahse a tha ber chu vawikhat hriatchhuah a nih veleh enkawl theih a ni a, complication a awm loh nan a veng thei bawk.

Hyperaldosteronism, aldosterone, adrenal glands, Conn’s syndrome, thisen sang, thisen sang, pressure, potassium, sodium, kal, hormone te a awm bawk