Damdawi hmang pawhin i thisen sang a tlahniam lo em ni? Hyperaldosteronism chungchang hi i zir dawn teh ang.

‘Engvangin nge leiah hian damdawi ei pawhin ka thisen sang a tlahniam loh ang?’ tih hi i ngaihtuah fo thin em? Mi thenkhat chuan chutiang harsatna chu an nei ve tho. Damdawi ei hnuah pawh an thisen sang thunun a harsat chang a awm. Hetiang hunah hian a chhan bulpui a awm thei em tih kan ngaihtuah a ngai a ni. Vawiin hian kan sawi dawn a, a chang chuan hriat harsa tak, mahse uluk taka enkawl a nih chuan tihdam theih a ni. Chu chu hyperaldosteronism a ni .

Hyperaldosteronism hi eng nge ni?

A awlsam zawngin, hyperaldosteronism chu i adrenal glands-in hormone aldosterone an tih tam lutuk hi a ni. Hetiang hian han ngaihtuah teh, aldosterone hi kan thisen sang control tu engineer te tak te ang mai a ni. Kan taksaa potassium leh sodium awm zat a tidanglam a, kan thisen sang chu a level dik takah a awm tir thin.

Tunah chuan, ‘Heng adrenal glands te hi eng nge ni?’ tiin i ngaihtuah mai thei. Hengte hi kan endocrine system a tel ve an ni . Kan taksain nitin a hnathawh theihna tura a mamawh hormone hrang hrang siamtu factory te tak te ang mai an ni. Heng adrenal gland pahnih hi kan nei a, chu chu a takah chuan kan kal chungah, cap ang maia awm a ni.

Hyperaldosteronism chi hrang hrangte chu engte nge ni?

Hyperaldosteronism hi chi hnih lian tak a awm a.

1. Primary Hyperaldosteronism: Hei hi a then chuan Conn’s syndrome an ti bawk. Heta thil thleng hi i adrenal glands te ngeiah hian thil dik lo a awm a, chu chuan aldosterone a siam tam lutuk a ni. Factory chhungah harsatna a awm a, thil an siam tam lutuk ang maiin han ngaihtuah teh.

2. Secondary Hyperaldosteronism: Hei hi adrenal glands-ah harsatna a awm lo. I taksa hmun dangah harsatna a awm a, chu chuan adrenal glands te chu a tichak a, aldosterone tam zawk a siam tan tir thin. Hei hian factory hian pawn lam atanga nghawng a neih avangin overtime a thawk tihna a ni.

Engti kawng pawhin, a tawpah chuan i thisenah aldosterone level a sang a, chu chuan thisen sang (hypertension) a thlen a, i thisenah potassium level a tlahniam bawk. Hetianga potassium tlahniam hi hypokalemia an ti a .

He natna hian tute nge a nghawng ber? Engtiang chiahin nge a hluar?

Hyperaldosteronism hi kum 30 leh 50 inkar ah a awm tam ber.Tin, he natna hi mipa aiin hmeichhiaah a tam zawk deuh bawk.

Hei hi zirchiangtute tan chuan engtiang chiahin nge a awm tih sawi a harsa a, a chhan chu a chang chuan hriat sual a nih vang a ni. Mahse zirchianna thenkhatah chuan thisen sang nei zinga 5% leh 10% inkar chuan primary hyperaldosteronism an nei thei tih an sawi. Mithiamte chuan damdawi ei theih loh thisen sang nei zinga 25% vel chuan he natna hi an nei thei niin an chhut. Chuvangin, chutiang chuan thil mak a ni lo, a dik em?

Hyperaldosteronism natna lan chhuahna chu engte nge ni?

Hyperaldosteronism symptoms hi mi hrang hrangah a inang lo thei a, chu chu a natna nasat dan azirin a ni. Mi thenkhat chuan symptoms an nei lo thei lo , a bik takin an natna hi a na lutuk lo a nih chuan.

Mahse, he natna lan chhuah dan ber leh langsar ber chu thisen sang (hypertension) , a bik takin damdawi hmanga pawh awlsam taka thunun theih loh thisen sang hi a ni .

Tin, symptom dang i neih chuan thisen sang sang lutuk leh/ emaw thisenah potassium level hniam (hypokalemia) vang a ni fo bawk.

Thisen sang (hypertension) avanga natna lanchhuahna awm thei te:

• Lu na
• Luak chhuak thei
• Vision a danglam thin
• Thâwk harsa

Thisena potassium level tlahniam (hypokalemia) avanga natna lan chhuah theih te:

• Muscle chak lohna - A nasat deuh thenkhatah chuan temporary paralysis ang chi hi a awm thei.
• Muscle twitching emaw twitching emaw (Muscle spasms) .
• Tingling leh rilru hahna
• Chau
• Tuihalna nasa tak (hei hi polydipsia an ti) .
• Zun chhuah fo thin

Tunah chuan i hrethiam ta, heng chhinchhiahna thenkhat hi natna dangah pawh a awm fo avangin, a chang chuan hei hi hriatchhuah a tlai lutuk thei.

Eng thilin nge hei hi a thlen?

Hyperaldosteronism thlen chhan hi primary emaw secondary emaw a zirin a inang lo. Engtin nge tih hi han thlir ila.

Primary Hyperaldosteronism awm chhan te

Ka sawi tawh ang khan Primary Hyperaldosteronism hi i adrenal glands ngeiah pawh harsatna a awm a, chu chuan aldosterone a siam tam lutuk a ni.

Hei hi a chhan tlangpui chu cancer ni lo tumor adrenal adenomas an tih adrenal glands a lo awm hi a ni . Hengte hi tumor te tak te, hlauhawm lo tak tak an ni a, mahse hormone aldosterone hi a chhuah tam lutuk thei a ni.

Chu bakah, a chhan dang engemaw zat hmuh tur awm lo tak tak a awm bawk :

• Unilateral adrenal hyperplasia - Hei hian a sir khatah adrenal gland pakhat chauh a hring a, a lian a, hormone tam zawk a siam tihna a ni .
• Aldosterone siamtu adrenocortical carcinomas - Hengte hi cancer natna thlentu an ni. Mahse, an tlem hle.
• Familial hyperaldosteronism type 1 - Hei hi nu leh pa atanga fate hnena genetically inherited a ni.

Secondary Hyperaldosteronism awm chhan te

Secondary hyperaldosteronism thlentu ber chu i kal ( kidney ) thlenga thisen lut tlem vang a ni .

Chutiang thil a thlen dan hriatthiam nan chuan hormone aldosterone hi kan thisen sang control tu hormone complex chain-a tel a ni tih i hriat a ngai a ni. Chain reaction angin ngaihtuah rawh.

He system hi renin-angiotensin-aldosterone system an ti a. Hetiang hian a thawk a ni:

1. I taksain thisen sang hniam emaw, i thisena sodium level hniam emaw a hriat chuan i kal (kidney) hian enzyme renin an tih chu a tichhuak thin .

2. He renin hian a kal a, i liver atanga siam angiotensinogen (angiotensin hmahruaitu) an tih chu angiotensin I ah a chantir a.(Angiotensin hi kan thisen kalna kawng tikhawtlai tu hormone a ni.)

3. A dawtah chuan he angiotensin I hi angiotensin II a lo ni ta a ni .

4. A tawp berah chuan he angiotensin II hian thisen kalna kawng a tikhawlo zual a, adrenal glands te chu hormone aldosterone chhuah tir turin a tichak bawk .

Tunah chuan han ngaihtuah teh, eng emaw chhan vanga kal-a thisen kal zat a tlahniam a nih chuan, kalte chuan, ‘Aw, ka thisen sang a tlahniam’ tiin an ngaihtuah a ni. Tichuan he renin-angiotensin-aldosterone system hi an activate sual a ni. Chumi rah chhuah chu taksaa aldosterone level a sang a, a tul tak tak lo nachungin.

Kidney-a thisen kal tihtlem thei leh secondary hyperaldosteronism thlen theituTlemte chu hetiang hi a ni:

• Obstructive renal artery disease - tui pipe khar ang mai.
• Renal hypertension a ni
• Taksa chhunga tui awmkhawmna (edema) , entirnan:
• Lung lam chak lohna
• Cirrhosis a awm thin
• Nephrotic syndrome hi kal natna a ni.

Engtin nge hei hi i diagnose?

Doctor chuan thisen test hmangin hyperaldosteronism a nei tih a hmuchhuak tlangpui . Mahse, mi tam tak chuan he natna hi an vei tih hmuhchhuah an ni ngai lo a, a chhan chu thisen sang thlen chhan leh risk factor dang tam tak a awm avangin.

Hyperaldosteronism i neih theihna chhinchhiahna langsar ṭhenkhat chu:

• Damdawi laka invenna thisen sang.
• I electrolyte thisen test report atanga i result te chu hetiang hi a ni:
• Sodium level sang deuh (hypernatremia) .
• Magnesium level hniam deuh (hypomagnesemia) .
• Tin, potassium level hniam (hypokalemia) .

I doctor chuan heng chhinchhiahna leh chhinchhiahnate a\anga hyperaldosteronism i neih theih a rinhlelh chuan thisen test bik pahnih a ti mai thei: Plasma Renin Concentration (PRC) emaw Plasma Renin Activity (PRA)

• Primary Hyperaldosteronism i neih chuan i PRC leh PRA level chu a tlangpui aia hniam a ni ang.
• Secondary hyperaldosteronism i neih chuan heng level te hi a tlangpui aia sang a ni ang.

Chu bâkah, aldosterone suppression test pawh i neih a ngai thei bawk . He test-ah hian sodium (salt) engemaw zat chu ka hmangin emaw, saline (IV) injection hmangin emaw hun engemaw chen pek che a ni. Tichuan, darkar 24 chhungin i zun sample te chu lakkhawm a ni a, chu zun chhunga aldosterone awm zat chu laboratory-ah teh a ni.

Heng test te hian hyperaldosteronism i nei tih a nemnghet a nih chuan i doctor chuan a chhan hriat nan test dang neih belh turin a ti thei ang. Entirnan, CT scan (computed tomography scan) hmanga cancer ni lo tumor hian hyperaldosteronism a thlen em tih enfiah a ni.Imaging test tih tir i ni mai thei .

Hei hi eng enkawlna nge ni?

Hyperaldosteronism enkawlna chu a chhan a innghat a, mahse a tum ber chu i thisen sang control hi a ni .

• Primary hyperaldosteronism, adrenal gland tumor avanga natna awm tan chuan doctor-te chuan operation hmanga lakchhuah an rawt tlangpui . Mahse, a then phei chuan heng tumor te hi damdawi chauh hmanga enkawl theih a ni. Operation hnuah pawh thisen sang i la nei thei a, chuvangin a thunun theih nan damdawi i ei a ngai mai thei.

• Secondary hyperaldosteronism hi damdawi hmanga i thisen sang control hmanga enkawl a ni a, chutih rualin a chhan bulpui (e.g., thinlung natna) pawh enkawl a ni bawk .

Hyperaldosteronism natna atana pui thei damdawi chi hrang hrang a awm a:

• A rilru a buai em em a, a rilru a hah em em bawk a.
• A rilru a hah lutuk chuan a rilru a buai em em a.
• Amiloride (Amiloride - Midamor®) tih a ni a, a man hi a to hle.

Thil pakhat hriat reng tur chu, hun rei tak chhunga aldosterone-blocking damdawi, Spironolactone , hman hian mipaah ​​side effect engemaw zat a thlen thei tih hi a ni. Entirnan, erectile dysfunction leh gynecomastia a awm thei. Chuvang chuan i doctor nen eng damdawi nge i tana tha ber, eng chen nge i ei tur tih leh a side effects te chu i sawipui a pawimawh hle.

Hei hi ven theih a ni em?

Dik tak chuan a tam zawkah chuan he hyperaldosteronism natna hi ven nan hian engmah tih theih a awm lo . A chhan chu kan taksa chhungril lam thil kal dan inthlak danglamna avanga lo awm a nih vang a ni. Mahse, nunphung hrisel zawm te, ei leh in inthlau tak ei te, leh exercise i tih te hian i hriselna zawng zawng chu i vawng reng thei a ni.

Hetiang dinhmun hi eng prognosis nge ni?

Hyperaldosteronism prognosis hi a chhan a innghat a ni.

• Primary hyperaldosteronism , hi a hmaa hmuhchhuah a nih a, uluk taka enkawl a nih chuan a rah chhuah tha tak a awm tlangpui . Tumor lakchhuah a nih chuan a dinhmun chu control a ni fo thin.
• Secondary Hyperaldosteronism a awm a, a awm loNatna hmalam hun chu a hnuaia damdawi lam dinhmun (e.g., thinlung natna, thin natna) control theih danah a innghat a ni.

Hyperaldosteronism avanga harsatna awm thei ber chu thisen sang vanga cardiovascular issues a ni. Chung zingah chuan:

• Atrial fibrillation - thinlung thawk mumal lo.
• Left ventricular hypertrophy - thinlung veilam chamber bang a thim.
• Lung natna
• Thai

Chuvangin he natna hi rang taka hriatchhuah a, enkawlna dik tak dawn a pawimawh hle.

Engtikah nge Doctor ka hmuh ang?

Hyperaldosteronism i vei tih hmuhchhuah a nih chuan i doctor hnenah i damdawi pek chu a thawk tha em tih hriat nan i doctor pan fo tur a ni . Doctor thupek zawm a pawimawh hle bawk.

Symptom thar i neih chuan, emaw, symptoms awm tawhah inthlak danglamna i hmu a nih chuan , i doctor hnenah hriattir nghal rawh.

A pawimawh ber chu, damdawi ei theih loh thisen sang i neih chuan i doctor hnenah i ngaihtuahna te, "Hyperaldosteronism ka nei thei ang em?" I dinhmun chu a ennawn thei a, test tul apiang a rawt thei bawk.

Thisen sang thlentu tam tak a awm tih hre reng ang che. Hyperaldosteronism hi chutiang zinga pakhat chauh a ni. Thu lawmawm tak chu hei hi enkawl theih a ni.

Take-Home Thuchah a ni

Okay, chuvangin tunah chuan kan sawi tawh, Hyperaldosteronism hi i hrethiam zawk ngei ka beisei. Hengte hi kan hriat reng tur thenkhat chu:

• Hyperaldosteronism chu adrenal glands-in hormone aldosterone a siam chhuah tam lutuk hi a ni.
• Hei hian thisen sang (hypertension) leh thisenah potassium level hniam (hypokalemia) a thlen thei a ni .
• A chi hnih a awm a, Primary ( adrenal glands ngeia harsatna awm) leh Secondary (hmun danga harsatna awm avanga adrenal gland stimulation) te an ni.
• Damdawi hmanga control theih loh thisen sang i neih chuan , hei hi i ringhlel tur a ni.
• Hei hi thisen test hmanga hriat theih a ni .
• Enkawlnaah hian thisen sang control leh a chhan bulpui enkawl a ni .
• A hmaa hmuhchhuah leh enkawl a nih chuan result tha tak a awm thei .

Hemi chungchanga zawhna dang i neih chuan i doctor hnenah zawhfiah theih a ni. Hrisel takin awm rawh!

` Hyperaldosteronism, Hyperaldosteronism, Aldosterone, Thisen sang, thisen sang, Potassium, Adrenal glands, Conn’s syndrome te hi a awm thei lo