Thisen var tlahniam hlauhawm tak: Agranulocytosis chungchanga hriat tur

I chau leh lethargic reng reng em? Khawsik, hmui natna, leh thil tenawm ber ber atang pawhin natna nei ang maiin i inhria em? Heng thil hnung lamah hian damdawi lam dinhmun kan sawi tam lo hle a, mahse a pawi hle thei a ni. Vawiin hian chutiang dinhmun pakhat kan sawi dawn a, chu chu Agranulocytosis a ni. Lungngai suh, thumal awlsam takin engkim hi han sawifiah ila.

Agranulocytosis hi eng nge ni tak tak?

A awlsam zawngin sawi ila, hei hi kan thisena thisen var chi khat tlahniam hlauhawm tak a ni. Kan taksa hi ram ang maiin han ngaihtuah teh. Tichuan kan taksaa natna thlentu hrik te hi ram beitu hmelma te an ni. Heng hmelma te beitu sipaite hi kan thisena thisen var (white blood cells) te hi an ni.

He thisen var sipai chhunga chakna bik pakhat chu granulocytes an ti a . He force-ah hian sipai chi thum an awm a, chungte chu:

• Neutrophils te pawh a awm
• Basophils te hi an ni
• Eosinophils a awm bawk

Heng cell-ah hian granule te te a awm a, chu chuan taksaa lut bacteria ang chi natna hrik tichhe thei enzyme a pai a ni. Heng cell pawimawh ber berte hi kan ruhro (bone marrow)-ah hian siam chhuah a ni.

Chuvangin, agranulocytosis chu heng indona cell granulocytes an tih te, a bik takin neutrophil cell tam ber te thisenah nasa taka tihtlem a nih hian a ni. Chutiang a nih chuan kan taksa invenna chu a chhe vek tawh mai. Hripui tenau ber atang pawhin awlsam takin kan damlo tan thin.

A tlangpuiin mi hrisel chuan thisen microliter khatah thisen var 1,800 aia tam a nei tur a ni. He number hi 500 hnuai lam a tlak chuan Agranulocytosis an ti a. Hei hi dinhmun hlauhawm tak a ni.

Agranulocytosis awm chhan hi engte nge ni?

Hetiang natna hi a chhan lian ber pahnih a awm a, chungte chu congenital leh acquired te an ni.

1. Pianpui atanga Agranulocytosis natna: 1.1.

Hei hi genetic defect vang a ni. Naupang thenkhat chu an piang hian an ruhroah thisen var siam chhuah theihna a tlahniam a. Entirnan, natna hmuh tur awm lo tak, Kostmann syndrome tih hi a awm a. Chutiang naupangte chuan khawsik te, natna hrik te, ruh lama harsatna te an nei fo thin.

2. A hnu lama lo awm Agranulocytosis:

Hei hi a awm dan tlangpui a ni. Nakin lawkah chhan hrang hrang avangin a thleng thei a ni.

Engtin nge damdawi hian he natna hi a thlen?

Damdawi hi a chhan lian ber a ni. Cancer dona damdawi thenkhat ang chi thil i ei hian mi zawng zawng thisen var (white blood cells) a tlahniam thin. Mahse damdawi thenkhat chu mi tam zawk tan harsatna thlen lo mahse mi tlemte tan agranulocytosis thlen thei a awm.

• Immune system hmanga thawk damdawi: Damdawi thenkhat hian kan taksa hian kan thisen var (white blood cells) te beitu antibody a siam chhuak thin.
• Bone marrow suppressant drugs: Damdawi thenkhat (e.g. valproic acid, carbamazepine, antibiotics thenkhat amoxicillin ang chi) hian ruhroa thisen var siam chhuah a titawp a.
• Anticancer damdawi leh rilru lam natna damdawi thenkhat: Hengte hi thisen var (white blood cell) tlahniam chhan lian tak a ni bawk.

Hetiang natna lan chhuah dan hi engte nge ni?

A tam zawkah chuan he natna chungchangah hian symptom bik a awm lo. Chhan dang avanga thisen test an tih hian accidentally hmuhchhuah a ni. Mahse, natna lan chhuahna chu immunity hniam vanga infection hmangin a lang chhuak thin.

• Khawsik sang tak a lo chhuak nghal
• Khua a vawt a, a khur bawk
• Kawngkhar natna
• Lu na
• Thawmhnaw hak
• Lymph node a lo hring chhuak
• Liver emaw spleen emaw a hring chhuak
• Chauhna leh hahna reng reng

He dinhmun hlauhawm ber chu hri kai tenau tak pawh hi natna khirh tak, nunna atana hlauhawm takah sepsis -ah a lo chang thuai thei a ni. Sepsis hi natna hrik chu taksa pumpuiah a darh a, thisen sang hlauhawm takin a tlahniam a, taksa chhungril peng hrang hrang thlengin a chhe thei a ni. Hei hi emergency medical treatment mamawhna dinhmun a ni.

Kum 65 chunglam, damdawi lam harsatna dang, kal natna emaw, thinlung natna emaw nei te chuan agranulocytosis natna an vei chuan harsatna an neih theihna a sang zawk hle.

Engtin nge enkawl a nih?

Hei hi enkawlna atana hmalakna hmasa ber leh pawimawh ber chu a chhan zawn hi a ni .

• A chhan enkawl dan: Hetiang dinhmun hi damdawi avanga lo awm a nih chuan doctor-in a tih angin damdawi i chawlhsan atanga kar 2-3 chhungin a dam tlangpui. A chhan chu infection a nih chuan enkawl tur a ni.
• Thisen var siam chhuahna tichaktu: Thisen var count tihpun nan Filgrastim ang chi injection bik pek thin a ni. Chungte chuan ruhro a tichak a, neutrophil siamchhuahna a tipung bawk.
• Infection enkawl dan: Bacteria infection i neih chuan i doctor chuan antibiotics a pe ang che. Viral emaw fungal infection tan chuan damdawi bik an pe ang che. Infection a nasat chuan damdawi inah dah a ngai mai thei a, intravenous (IV) treatment pek a ngai mai thei.
• Bone marrow transplant: Enkawlna dang a hlawk loh chuan matched donor atanga bone marrow transplant chu a tawp ber atan ngaih theih a ni.

Agranulocytosis vei chuan engtin nge a enkawl ang?

Hetiang dinhmun hi i neih chuan i immune system a chak lo hle a, chuvangin natna hrik laka inven nan fimkhur zual a ngai a ni.

Agranulocytosis hi natna khirh tak ni mahse, a chhan hriatchhuah a, uluk taka enkawl a nih chuan tihdam theih a ni fo. A pawimawh ber chu infection chhinchhiahna tenau (khawsik, taksa na) i hmuh veleh doctor pan nghal tur a ni. Thil tih vat chuan harsatna lian tham tak tak a awm loh nan a pui thei a ni.