Ka hnungzang na fo, a nghet lo... Hei hi Ankylosing Spondylitis (AS) hi a ni em?

I naupan lai atang tawhin i hnungzang leh i hip area-ah pawh na i nei fo em? A bik takin zing i thawh hian i hnungzang a khauh a, eng emaw chen chu ben emaw, hna engmah thawh emaw a harsat em? Chutiang thil chu kan theihnghilh fo thin a, "a hliam a ni thei" emaw, "hnathawh avanga hah vang pawh a ni thei" emaw tiin kan ngaihtuah fo thin. Mahse, hei hi tlem tal ngaihven zawk ngai dinhmun a ni thei. Vawiin hian he natna ang chi, mi tam takin an hriat chian loh, mahse fimkhur a pawimawh em em chu kan sawi dawn a ni. Chu chu Ankylosing Spondylitis a ni .

Ankylosing Spondylitis (AS) hi eng nge ni mai?

A awlsam zawngin sawi ila, ruh natna chi khat a ni a, chu chuan ruh ruh (spine) a tichhe thei a ni. I ruhro leh sacroiliac joints a nghawng ber a, chutah chuan i ruh hnuai lam chu i hip ruh nen a inzawm a ni. He natna hian i taksa immune system chuan heng ruhte hi a rawn bei sual a, chronic inflammation a thlen thin .

He inflammation hi hun kal zelah a awm reng avangin hnungzang leh hip na a thlen thei a, ruhroah flexibility a ti tlem thei a, movement pawh a tikhawtlai thei bawk . Mi thenkhat phei chuan hun kal zelah kawng khauh tak an nei thei bawk.

Khawvel puma mi 1000 zinga pakhat velin he natna hi an nei thei niin an sawi. Hei hi damdawi a la awm lo. Mahse lungngai suh , natna hi dik taka hmuhchhuah a nih a, doctor thiam thurawn anga enkawl a nih chuan he natna hi i thunun tha thei a, nun pangngaiin i nung thei bawk.

Tute nge he natna vei theihna sang zawk?

Engvangin nge mi thenkhatin he natna hi an neih? A chhan dik tak chu hmuhchhuah ni lo mah se, scientist-te chuan a hlauhawmna tipungtu thil engemaw zat an hmuchhuak a ni.

Genetic nghawng (Genes) 1.1.

He natna thlentu ber chu genetic influences a ni tih hmuhchhuah a ni.

• HLA-B27 gene: Hei hi he natna nena inzawm ber gene a ni. He gene hian kan taksa immune system chu ‘hengte hi kan cell ngei an ni’ leh ‘ram dang virus emaw bacteria emaw’ tih hriat theihna turin a pui a ni. He gene chi khat (`HLA-B27` variant) nei te hi AS vei theihna a sang zawk.
• A pawimawh ber: Mahse hetah hian a pawimawh ber chu he `HLA-B27` gene hi i taksaah i neih vang mai mai hian he natna hi i vei dawn tih i sawi thei lo. He gene nei tam zawk hian he natna hi an nei ngai lovang. Tin, he gene nei lote pawhin he natna hi an nei thei bawk.
• Genes dang: Chu bakah, immune system nena inzawm gene dang engemaw zat, `ERAP1`, `IL1A`, leh `IL23R` te chu he natna nen hian an inzawm tih hmuhchhuah a ni bawk.

Inflammatory Condition dangte pawh a awm thei

AS vei thenkhat chuan inflammatory condition dang an nei thei bawk. Entir nan:

• Psoriasis natna a ni
• Ulcerative Colitis a awm thei
• Crohn natna a ni

Chuvangin, i chhungkuaa mi tu emaw hian heng natna, emaw, Ankylosing Spondylitis emaw a neih chuan nang pawh i hlauhawm thei bawk.

Gender leh kum hian engtin nge a nghawng

AS natna lan chhuah dan hi kum 40 an tlin hmain a intan tlangpui a, a chang chuan kum 16 atang pawhin a lo lang thei a, chu chu `juvenile-onset ankylosing spondylitis` an ti a ni.

He natna awm dan hi mipa leh hmeichhia a zirin a inang lo. Heng inthlauhna te hi hriat chian chuan natna hriat hmasak kawngah nasa takin a pui ang.

Hmeichhiaten natna an hmuhchhuah an tlai fo chhan pakhat chu khawtlang leh doctor-te pawhin hei hi ‘mipa natna’ a nih thu an ngaihdan dik lo vang a ni. Tin, hmeichhia symptoms hi mipa symptoms nen a danglam avangin (MRI scan-ah pawh spinal damage tlem zawk a lang thei) natna hriatchhuah nan hun a duh rei thei bawk.

Hnam leh hnam pawhin chanvo a nei em?

Ni e, hnam hian eng emaw chen chu hmun a chang a ni. Zirchianna atanga a lan dan chuan he natna hi mipa hring zingah a tam zawk a, a bik takin Europe hmar lam ramteah a hluar zawk a ni. African mipa hring zingah a tam lo hle.

Mahse hetah hian thil pawimawh tak a awm. He natna vei theihna hi a tlem hle nachungin, zirchianna atanga a lan dan chuan mipa hring hian AS a vei a nih chuan natna hi a nasat phah thei a ni .

Tin, AS vei mipa hring zinga 90% vel chuan HLA-B27 gene an nei bawk. Mahse, AS vei mipa hring zinga 50%-60% chauhvin he gene hi an nei a ni. Chuvangin diagnosis kan siam dawnin race leh genetic background ngaihtuah a pawimawh hle.

Diagnosis tihkhawtlai leh a nghawng dan

Mi tam tak tan chuan natna lan chhuah tan hnua dik taka hriat theih nan kum 8 atanga kum 10 vel a ngai a ni. Hetianga tihkhawtlai hi hmeichhiate tan chuan a rei zawk thei a, a bik takin.

Hetianga tihkhawtlai hian enkawlna a tikhawtlai a ni. Hei hian natnain a tihchhiatna a tipung a ni. Hun a kal zel a, ruhro ruhte chu a inzawm khawm (fusion) thei a, ruhro chetna pawh a bo vek thei bawk.

Chuvangin, i hnungzang na reng reng, zing lama natna, emaw, symptom dang emaw i neih chuan, a bik takin hmeichhia i nih chuan , khawngaihin ngaihthah suh. Doctor thiam tak hmu la, i natna lan chhuah dan chiang takin sawi rawh. A tul chuan X-ray emaw MRI scan emaw dil hlau suh. Nangmah thu sawi turin dikna i nei a ni.