He aha te pānga o te menopause ki tō maimoatanga mate pukupuku ū?

E mārama ana ahau ki te taumaha me te whakamataku o te wā ka kitea he mate pukupuku ū koe. I tētahi taha, kei reira te manukanuka mō te mate, ā, i tētahi atu taha, ina kīia e ngā tākuta ngā kupu pēnei i te "(Chemotherapy)" me te whakaora homoni , ka nui ake te pōhēhē o tō hinengaro, kāore? "Ka whiwhi chemo anō hoki ahau? Ka hinga ōku makawe? Ka uaua rānei mō tōku tinana?" He maha ngā pātai kei roto i tō hinengaro. Engari kaua e manukanuka. I tēnei rā, ka kōrero tātou mō te hiranga o tō tau me te mea kua pāngia koe e te menopause, hei whakatau i te maimoatanga ka hoatu ki a koe.

I mua, tata ki te katoa i whiwhi i te rongoā chemotherapy i te kitenga kua horapa te mate pukupuku ū ki ngā kōpū lymph. He rite ki te pupuri i te hama me te hanga i ngā mea katoa kia rite ki te whao. Engari inaianei kua tino whanake te rongoā. Ināianei kua mōhio tātou ehara i te mea he rite katoa ngā mate pukupuku ū, ā, ehara i te mea ka tauhohe katoa ngā tūroro ki te maimoatanga kotahi. I ētahi wā ka nui ake ngā pānga taha o te rongoā chemotherapy i ngā painga. Nō reira, inaianei kua nui ake te aro o ngā tākuta ki te rahi o te pukupuku me te wāhanga o te mate pukupuku, engari ki te āhua koiora o te mate pukupuku.

He aha te hiranga o te wā pāheketanga ki tēnei pūrākau?

Ahakoa kua pāngia koe e te menopause, te wā e mutu ai ō paheketanga ā-marama, he mea tino nui tēnei mō te maimoatanga o te mate pukupuku o te ū. He maha ngā take mō tēnei.

Ki te kī māmā noa, ko te mate pukupuku ū i roto i ngā wāhine taitamariki, kāore anō kia pāhekeheke, he nui ake te tūponotanga ka kaha ake i te mate pukupuku i roto i ngā wāhine kua pāhekeheke .

Hei tāpiritanga, ka whakatauhia hoki te momo maimoatanga ka whiwhi koe. Hei tauira, ki te mea he mate pukupuku e whakawhirinaki ana ki te homoni tōu, ka rerekē te momo maimoatanga homoni ka taea e koe te whiwhi i runga i tō āhua paheketanga.

• I muri i te paheketanga: Tērā pea ka hoatu he rongoā ki a koe pēnei i a Arimidex, e aukati ana i te tinana ki te whakaputa i te homoni estrogen.
• Mena kei mua koe i te paheketanga: Kei te whakaputa tonu ō ovaries i te estrogen, nō reira kāore e tino whai hua ngā rongoā pēnei i a Arimidex. Nō reira, ka tohua e tō tākuta he rongoā e kiia nei ko Tamoxifen. Mā te aukati i te karere e tukuna ana e te estrogen ki ngā pūtau matepukupuku ka mahi tēnei.

Koiora o te Matepukupuku: Ngā Kaiwhakawhiwhi Homoni me te HER2

Āe, me hohonu ake tā tātou keri. Me waiho ki te taha te tika o te rongoā homoni māu, ko te pātai nui e whai ake nei ko te hiahia rānei ki te rongoā matū.

He maha ngā wā ka ahu mai tēnei whakatau i ngā momo kaiwhakawhiwhi i runga i te mata o ō pūtau matepukupuku . Whakaarohia ēnei kaiwhakawhiwhi hei 'pūihi' i runga i ngā pūtau matepukupuku. Ka hopukina e ēnei pūihi ngā 'tohu' e hiahia ana te matepukupuku kia tipu. E rua ngā momo matua o ngā kaiwhakawhiwhi ka tirohia e mātou.

1. Ngā Kaiwhakawhiwhi Homoni (HR): Ngā kaiwhakawhiwhi e tairongo ana ki ngā homoni estrogen me te progesterone.

2. Kaiwhakawhiwhi HER2: Ko tētahi atu pūmua tēnei e āwhina ana i te tipu o ngā pūtau matepukupuku.

Tirohia te ripanga i raro nei mō te whakarōpūtanga o ngā mate pukupuku me te whakatau i te maimoatanga i runga i te huinga o ēnei.

He aha te whakamātautau Oncotype Dx?

Mena he HR-positive tō mate pukupuku, he HER2-negative, arā, ko te momo tuatahi i roto i te ripanga i runga ake nei, ko te pātai "Me whai chemo ahau?" te mea tino uaua ki te whakautu. I roto i ēnei take ka whakamahia e ngā tākuta he whakamātautau ira pēnei i te `Oncotype Dx` .

Ka tātarihia e tēnei whakamātautau ngā ira e 21 i roto i tētahi tauira iti o tō matepukupuku. I runga i tēnei, ka hoatu he kaute e whakaatu ana mēnā he iti, he taurite, he nui rānei te mōrearea o tō matepukupuku ki te hoki anō mai ā muri ake nei.

• Kaute iti: He maha ngā wā ka ora ake koe me te kore he rongoā chemotherapy .
• Mena he teitei te kaute: Ko te rongoā matū te mea tino tika.

Engari he tokomaha ngā tāngata e whiwhi ana i te kaute waenga . Koinei te wāhi ka ara ake anō te raruraru.

Ngā whakautu mai i ngā rangahau hou

He waimarie, e rua ngā rangahau nunui o nā tata nei, arā, ko TAILORx me RxPONDER, kua homai he whakautu tino pai ki te pātai me aha ēnei wāhine he toharite te kaute. Kua whakaū anō ēnei rangahau i te hiranga o te wā pāheketanga.

• Whakamātautau TAILORx (mō te hunga kāore anō kia horapa te mate pukupuku ki ngā kōpū lymph):
• E whakaatu mārama ana tēnei rangahau kāore he painga anō o te chemotherapy ki ngā wāhine kua pāngia e te menopause, ā, he taurite te Oncotype Dx. He rawaka noa iho te rongoā homoni mā rātou.
• Te rangahau RxPONDER (mō te hunga mate pukupuku kua horapa ki ngā kōpū lymph):
• E whakaatu ana hoki tēnei i te mea kotahi. Ahakoa kua horapa te mate pukupuku ki ngā kōpū lymph, ko te nuinga o ngā wāhine kua pāngia e te menopause , kāore i te tino whai hua mai i te chemotherapy.
• Heoi, he rerekē rawa te kōrero mō ngā wāhine kei mua i te paheketanga, inā koa ko te hunga kei raro iho i te 50 tau te pakeke. Ina tāpirihia te chemotherapy ki te rongoā homoni mā rātou, ka tino piki ake te kaha ki te aukati i te hokinga mai o te mate pukupuku.

Ki te kī ngāwari, mēnā he wahine taitamariki koe kei mua i te paheketanga, ka taea e te chemotherapy te noho hei patu kaha hei whakaora i tō ora. Engari mēnā kua mutu tō paheketanga, tera pea ka pai ake ngā hua o te rongoā homoni me te kore e pāngia e ngā pānga taha.

Te whakatau whakamutunga me ngā mea hei whakaaroaro

Ahakoa ēnei mea katoa, e mārama ana pea koe ki te uaua o te whakatau i ēnei mea ko koe anake. Koia te mea nui kia kōrerohia whānuitia ēnei mea katoa ki tō tākuta.

Mena kei mua koe i te paheketanga, inā koa kei te tīmatanga o te 40 tau, me maumahara ki tētahi atu mea. Ka taea e te chemotherapy te whakamutu i ō paheketanga mō ake tonu atu, ā, ka wawe te paheketanga. Mō te hunga taitamariki, ka mutu pea ō paheketanga mō te wā poto, kātahi ka tīmata anō. Engari ki te mea kei te tumanako koe kia whānau tamariki ā muri ake nei, kia mōhio koe ki te kōrero ki tō tākuta mō te tiaki i te momonatanga i mua i te tīmatanga o te maimoatanga.

Hei te mutunga, mā kōrua ko tō tākuta e whakatau ko tēhea te maimoatanga pai mōu. I roto i taua kōrero, ko te momo mate pukupuku, te wāhanga, te kaute Oncotype Dx, me te mea kua mutu tō paheketanga he kaupapa nui katoa hei kōrero.