Kua rongo pea koe i te kupu 'Opioid'. He rongoā mamae kaha ēnei e tohua ana e ngā tākuta hei whakahaere i te mamae nui. Ka whakamahia ēnei mō ngā āhuatanga pēnei i te mamae o te mate pukupuku, i muri i ētahi pokanga, me ētahi atu. Engari nā ō rātou pānga kaha, ki te whakamahia hē, ki te nui rawa te horopeta, ki te waranga rānei tetahi ki ēnei, ka waiho hei tūraru nui ki te ora. Nō reira, i tēnei rā ka kōrero tātou mō tētahi momo rongoā motuhake e whakamahia ana hei whakaora ora i roto i ēnei āhuatanga morearea, e mahi ana pērā i te 'kaitautoko'. Ko ngā Kaitautoko Opioid tēnā.
He aha te tikanga o tēnei Opioid Antagonist?
Hei mārama ki tēnei, me titiro tuatahi tātou ki te mahi a ngā rongoā mamae opioid i roto i ō tātou tinana. Whakaarohia tō tātou pūnaha io, inā koa te roro me te tuaiwi, he 'kēti' ririki. I roto i te rongoā, ka kiia ēnei he 'kaiwhakawhiwhi'. Ina uru te rongoā mamae opioid ki te tinana, ka herea ki ēnei kēti ka 'whakatuwhera' i a rātou, ka whakaiti i te mamae me te waihanga i te wairua oranga (euphoria).
He rite ngā kaiwhakahē opioid ki tētahi kī rerekē e uru ana ki te raka kotahi. Engari ina kuhua tēnei kī ki roto i te raka, kāore e huakina te tatau. Engari, ka mau ki roto i te raka, ka ārai katoa i te huarahi mō te kī opioid ki te tomo. He māmā noa iho, ka ārai ēnei rongoā i ngā kaiwhakawhiwhi opioid, ka ārai i te mahi a ngā opioid. Koia te take ka taea e rātou te whakakore i ngā pānga kino o te nui rawa o te opioid.
Ko te mea nui, ki te kore he Opioid i roto i tō tinana, kāore he pānga o tēnei rongoā Opioid Antagonist. Ka mahi anake ina he Opioid kei roto i tō tinana.
He aha ēnei rongoā, ā, he aha te whakamahinga mō rātou?
He maha ngā momo rongoā kei roto i te akomanga Opioid Antagonist. He kaupapa motuhake tā ia momo. Me titiro tātou ki ngā momo matua.
| Ingoa o te rongoā | He aha te nuinga o tōna whakamahinga? | Me pēhea te hoatu |
|---|---|---|
| Naloxone | Koinei te rongoā ohorere mō te nui rawa o te opioid. Ka whakamahia hei whakakore i te pouri manawa i puta mai i ngā opioid. He rongoā whakaora ora. | Hei werohanga (ā-uaua, ā-pūtau rānei) hei rehu ihu rānei (hei tauira, Narcan®, Kloxxado®) |
| Naltrexone | He maimoatanga tiaki mō ngā mate whakamahi opioid me te waipiro. Ka ārai i te harikoa o ngā raau taero, ā, ka āwhina ki te whakaiti i te hokinga mai ki te whakamahi. | Hei werohanga, hei pire rānei hei horomia. (hei tauira, Vivitrol®, ReVia®) |
| Methylnaltrexone | E whakamahia ana hei rongoā i te mate puku mārō i puta mai i te opioid mō te hunga e tango ana i ngā rongoā whakamamae opioid mō te wā roa. Ka ārai noa i ngā kaiwhakawhiwhi i roto i ngā whekau, engari kāore e pā ki te roro. | Hei werohanga, hei pire rānei hei horomia. (hei tauira, Relistor®) |
| Nalmefene | He rongoā rite ki te Naloxone. Hei rongoā i te nui rawa o te opioid, ka roa ake tōna noho ki te tinana. Engari kāore i te tino whakamahia pērā i te Naloxone. | Hei werohanga. (hei tauira, Revex®) |
Te hiranga motuhake o te Naloxone
Nā te mate urutā opioid, kua whakangungua ngā kaimahi ratonga ohorere pērā i ngā pirihimana me ngā kaimahi waka tūroro i roto i ngā whenua maha o te ao ki te kawe me te tuku Naloxone. Mēnā ka mutu te manawa o te tangata nā te nui rawa o te opioid, mā te tuku Naloxone i roto i te 2 ki te 5 meneti ka taea te whakaora i te ora mā te whakahoki mai i te manawa noa.
He aha ngā pānga taha o ēnei rongoā?
Ko ngā pānga matua, me ngā pānga wawe tonu o Naloxone, Naltrexone, me Nalmefene, ko ngā tohumate o te tango opioid.Te tūnga.
Whakaarohia tētahi tangata e tino waranga ana ki ngā opioids. Kua taunga katoa tōna tinana ki aua opioids. Ina hoatu ohoreretia e koe tētahi rongoā pēnei i te Naloxone ki tētahi, ka whakakorea ohoreretia ngā opioids katoa i roto i tōna tinana. Kātahi ka puta te urupare a te tinana ki tēnā.
Ko ngā tohu matua ko:
- Huka (putanga huka)
- Te roimata nui mai i ngā kanohi
- Te mimi pinepine (te kore e taea te pupuri i te mimi)
- Te pikinga ake o te tere o te manawa (Te hau nui)
- Te wera nui
- Te pikinga o te tere o te ngakau (Tachycardia)
- Te mamae nui o te uaua
- Whakapairuaki me te ruaki
- Pupuhi (korere)
- Te āwangawanga nui me te manukanuka
Ka rerekē te kaha o ēnei tohu i ia tangata, i ia tangata, i runga i te roa o te wā e whakamahi ana rātou i ngā opioids me te momo i whakamahia e rātou.
Engari he mea nui kia maumahara ki tēnei. I roto i te hōhipera, hei tauira i te Tari Whawhati Tata (ETU) , ka taea e ngā tākuta te whakahaere pai i ēnei tohumate tango. Ka taea tēnei mā te hoatu i te tote, me ētahi atu rongoā pēnei i te Methadone me te Buprenorphine.
Ngā pānga taha o te methylnaltrexone
I te mea ko ngā whekau te nuinga o te pānga o tēnei, e pā ana hoki ngā pānga taha ki tēnā.
- Mamae puku
- Te whakakī i te puku
- Whakapairuaki ngawari, korere rānei
- Ānini
- Te hurihuri o te uaua
- Pōuriuri
Nā, he aha ngā painga o ēnei rongoā?
Ahakoa ngā pānga taha, he nui atu ngā hua pai o ēnei rongoā i ērā.
He rongoā whakaora ora a Naloxone me Nalmefene. Mēnā ka tere te rongoā me te tika mō te nui rawa o te opioid, ka taea te whakaora i te ora o te tangata. Koinei te mea nui rawa atu. Mēnā ka kite koe i tētahi e kore e mōhio, ā, he ngoikore te manawa nā te nui rawa o te opioid, me kawe tonu ia ki te Wāhanga Maimoatanga Ohotata (ETU) o te hōhipera. Waihoki, mēnā e hiahia ana koe ki ētahi mōhiohio mō tētahi paitini, ka taea e koe te waea atu ki te National Poisons Information Center i te Hōhipera ā-Motu o Colombo mō ētahi tohutohu.
He taputapu tino nui te Naltrexone e whakamahia ana hei rongoā i te āhua uaua o te mate whakamahi matū. Heoi, kāore e taea e tēnei rongoā anake te whakaora i tēnei āhua. Me whai hinengaro hinengaro, whakaoraora, me ētahi atu ratonga tautoko.
Nō reira, he momo rongoā tino whai hua ngā Antagonists Opioid. Mena he āwangawanga, he mataku rānei āu mō ēnei rongoā, mō ō rātou pānga taha rānei, kōrero noa ki tō tākuta mō ēnei. Ka taea e ia te hoatu ki a koe te tohutohu me te tautoko tika e hiahiatia ana e koe.
Karere Tangohia ki te Kāinga
- Ko te rongoā ārai opioid he momo rongoā e aukati ana i te mahi a ngā rongoā whakamamae opioid.
- He maimoatanga ohorere te Naloxone hei whakaora i te manawa me te whakaora i te ora mēnā ka nui rawa te opioid.
- He maimoatanga tiaki te Naltrexone mō te waranga opioid, te waranga waipiro rānei. Ka aukati i te ahuareka o ngā raau taero.
- Ina hoatu ēnei rongoā ki tētahi tangata e waranga ana ki ngā opioids, ka pā mai ngā tohumate whakamomori kino, engari ka taea te whakahaere i ēnei i roto i te hōhipera.
- Ahakoa he mea tino nui ēnei rongoā, me whai kaupapa whānui te rongoā i te waranga tarukino, tae atu ki te tohutohu hinengaro.
- Me kōrero tonu koe mō ēnei rongoā ki tō tākuta, ā, me rapu tohutohu tika hoki.
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