He mate ate tōu e kiia nei ko te PBC, ko te Primary Biliary Cholangitis rānei? Mēnā koinā, tērā pea kāore i pai te rongoā tuatahi i tohua e tō tākuta ki tāu i tumanako ai. Kaua e manukanuka. He maha ngā tāngata kua pāngia e ngā wheako rite. Ko te mea nui kia noho tumanako tonu, kia mōhio hoki ki ngā mea ka taea e koe te mahi i muri mai. I tēnei rā, me kōrero tātou mō ngā mea ka taea e koe te mahi i tēnei wā, me ngā maimoatanga hou e wātea ana.
Tuatahi, he aha te PBC i roto i ngā kupu māmā noa iho?
He mate uaua, he mate roa te PBC, e whakaekehia ana e te pūnaha ārai mate o tō tātou tinana ngā awaawa iti o roto i tō tātou ate. Whakaarohia ēnei awaawa he paipa iti i roto i tō tātou ate. Ko tā rātou mahi matua he kawe i te awaawa, he wai e āwhina ana ki te nakunaku kai, i waho o te ate.
Ināianei, mō te PBC, ka pakaru ēnei paipa i roto i ō tātou ake pūtau pūnaha ārai mate. Kātahi ka aukatia ēnei paipa, ā, kāore e rere tika te au o te ate, ka mau ki roto i te ate. Pērā i ngā motuka e mau ana i roto i te waka. Ina kohia te au o te ate i tēnei ara, ka tīmata te kino i ngā pūtau ate. I roto i te wā, ka puta he kiriuhi i te ate i tēnei kino. Ka kiia tēnei he fibrosis . Ina kaha ake te kino o tēnei āhuatanga, ka arahi pea ki te mōrearea o te cirrhosis, he āhuatanga e kiia nei ko te ngoikore o te ate.
He rerekē tēnei i ētahi atu mate pūnaha ārai mate. Nā te mea kāore te PBC e pai te aro ki ngā rongoā pehi pūnaha ārai mate e whakamahia ana mō ētahi atu mate pūnaha ārai mate. Ko tētahi take pea kua pakaru kē te ate i te wā e tautuhia ai te mate. Kaua e manukanuka, nā te whanaketanga o te pūtaiao, kua kitea ngā maimoatanga pai mō tēnei.
Te taahiraa tuatahi i roto i te maimoatanga: rongoā UDCA
He maha ngā whāinga matua o te rongoā i te PBC: te whakaroa i te haere whakamua o te mate, te whakahaere i ngā tohu, me te ārai i ngā raruraru mai i te kino o te ate.
Kia kitea tō mate PBC, ko te rongoā tuatahi ka tīmata pea tō tākuta ki te inu ko te waikawa Ursodeoxycholic , arā, ko te UDCA . Tērā pea ka mōhiotia e koe ko te ingoa waitohu Ursodiol. Ka āwhina tēnei rongoā i te ate ki te tuku i te au e piri ana ki te ate, me te whakaiti i te hanganga o te kiriuhi (fibrosis) i roto i te ate. He mea nui tēnei, nā te mea ko te kiriuhi te mea ka arahi pea ki te cirrhosis me te ngoikore o te ate.
Engari ko te pono, kāore te UDCA e mahi mō te katoa. Koinei te kaupapa matua e kōrerohia ana i tēnei rā.
He aha te kore e ranea ai te UDCA anake?
Kua kitea e ngā rangahau, i waenga i te 25% me te 50% o ngā tūroro e tango ana i te UDCA kāore e whiwhi i ngā hua e tumanakohia ana mai i te rongoā. Ko te tikanga tēnei, kāore ā rātou whakamātautau mahi ate e whakaatu ana i te whakapainga nui.
Mā tēnei, e rima ngā whakarea o te pikinga ake o te tūponotanga o te tangata kāore e pai te urupare ki te UDCA ki te whakawhanake i te cirrhosis. Ā, e toru ngā whakarea o te pikinga ake o te tūponotanga o te mate i te mate. Nō reira, ki te kore e mahi te UDCA, he mea nui kia kōrero koe ki tō tākuta mō ngā mahi e whai ake nei, kaua e haere tonu ki te whakamahi.
Kei te whakaaro koe he aha te kore e mahi tika ai te UDCA? Tērā pea he maha ngā take mō tēnā.
| Ngā take mō te korenga o te maimoatanga UDCA | He whakamārama māmā |
|---|---|
| Kua pāngia kētia koe e te mate ate (cirrhosis) | Mena kua pakaru kē te ate i te wā i tautuhia ai te mate, tera pea he uaua ki te whakahaere i te mate mā te UDCA anake. |
| Ngā taumata GGT teitei | Mena ka whakaatuhia e tō whakamātautau toto he tino tiketike ngā taumata o te whākōkī ate e kiia nei ko te gamma-glutamyl transferase (GGT) i te wā tuatahi i tāpaetia ai koe ki te mate, he take anō pea tēnā mō te ngoikore o te urupare ki te maimoatanga. |
| Kāore e taea e te tinana te aro atu ki te rongoā. | Kāore e taea e te tinana o ētahi tāngata te aro atu ki te UDCA, arā, kāore e taea e rātou te tango i te rongoā i te horopeta kua whakaritea nā ngā pānga taha. |
Mena kei a koe tētahi, ētahi rānei o ēnei take, kua tae ki te wā ki te whakaaro ki tētahi maimoatanga tuarua . Ehara i te mea ko te whakapai ake i ngā hua o tō whakamātautau toto anake te whāinga i konei. He mea nui anō hoki kia whakahaere i ngā tohu e pā ana ki tō kounga o te oranga, pērā i te mākati e kore e taea te manawanui, te ngenge nui, me te kore moe . Nā te mea kāore te UDCA e whakarato i te nui o te whakamarie mō ēnei tohu.
Ngā maimoatanga tuarua: He aha ēnei kōwhiringa hou?
Kei te tere haere te whanaketanga o ngā kōwhiringa maimoatanga mō te PBC. He maha ngā rongoā hou kei ngā wāhanga whakamutunga o te whakaaetanga. Me titiro tātou ki ngā maimoatanga o nāianei me ngā maimoatanga kei te haere mai.
Waikawa obeticholic (OCA)
Mena kāore te UDCA e pai te mahi, ki te kore rānei e taea e koe te aro atu ki te UDCA, ko te rongoā matua e whai ake nei ka whakaarohia e tō tākuta ko te waikawa obeticholic , te OCA rānei. Ko te tikanga kei raro i te ingoa waitohu Ocaliva.
I ētahi wā ka taea te hoatu i te OCA me te UDCA. Arā, ka whakamahia ngātahi ngā rongoā e rua. Nō roto te OCA i tētahi rōpū rongoā e kiia nei ko ngā agonists farnesoid X receptor . I roto i ngā kupu ngāwari, ko tana mahi,
1. Ka whakaiti i te nui o te au e whakaputaina ana e te ate.
2. Āwhina ki te pana i te au i roto i te ate.
Mā tēnei, ina whakamahia ko te OCA anake, ka pai ake rānei te mahi a te ate, ā, ka heke te tere o te whara o te ate.
Engari ko tētahi o ngā pānga taha matua o te OCA ko te whakanui ake i te mākati i roto i ngā tūroro PBC. Nō reira, ki te piki ake te mākati i muri i te tīmatanga o tēnei rongoā, me kōrero koe ki tō tākuta mōna. Kātahi ka taea e ia te whakarerekē i te horopeta, te hoatu rānei i tētahi atu maimoatanga ki a koe.
Kei te whanake tonu te mara o te maimoatanga PBC, nō reira he mea nui kia noho whakapā atu tō hauora ki tō tākuta me te matapaki i ngā maimoatanga hou.
Karere Tangohia ki te Kāinga
- He mate ate roa te PBC e hiahia ana kia rongoatia. Kaua e warewaretia.
- He rongoā tino nui te UDCA mō tēnei, engari kāore pea e rite ngā hua mō te katoa.
- Ki te kore e pai ngā hua o te UDCA, ki te kore rānei e taea te aro atu ki ngā pānga taha, ehara i te mutunga o te maimoatanga. Inaianei kei reira ngā maimoatanga raina tuarua whai hua, pērā i te OCA.
- Kaua e whakatau ko koe anake i ngā whakatau maimoatanga. Kōrerohia mā te mahorahora ki tō tākuta mō tō maimoatanga, ngā whakamātautau toto, me ngā tohumate.
- He mea nui te tirotiro hauora me te whakamātautau toto (ina koa ko ngā whakamātautau mahi ate) i te wā tika hei whakahaere i te mate.
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