Kua motuhia tō maihao? Kua ngaua rānei koe e te pepeke, ā, kua whero, kua pupuhi, kua mamae hoki te wāhi? Kua pā mai ēnei wheako ki a tātou katoa. Ā, ki te mea he wahine koe, e mōhio ana pea koe ki te mamae e pā ana ki a koe i tō paheketanga. I tēnei rā, ka kōrero tātou mō tētahi karere matū iti engari tino kaha kei muri i ēnei mea katoa, engari kāore tātou e kōrero nui mōna, ā, koinā te mea ka kōrerohia e tātou. Ko te ingoa ko ngā Prostaglandins . Ahakoa he ahua rerekē te ingoa, he maha ngā mahi o ia rā o ō tātou tinana e whai wāhi ana ki ēnei.
Hei whakarāpopototanga, he aha ēnei prostaglandin?
Ko ngā prostaglandin he rōpū lipids (he momo ngako) e hangaia ana i roto i tō tātou tinana ina pakaru ngā kiko, ina pangia, ina rānei i roto i ngā āhuatanga motuhake. Ahakoa he rite ā rātou mahi ki ngā homoni, ehara i te mea he homoni.
Inaianei pea kei te whakaaro koe, "Nā, he aha te rerekētanga i waenga i ngā homoni me ēnei?" Whakaarohia, ko ngā homoni i roto i ō tātou tinana he rite ki te ratonga mēra o te motu. Ko ngā homoni, e hangaia ana i te wāhi kotahi, pērā i te repe pituitary i roto i te roro, ka haere puta noa i te tinana mā te toto, ka tuku karere ki ngā wāhanga rerekē o te tinana.
Engari ehara ngā Prostaglandin i te pērā. He rite rātou ki tētahi tangata o te kāinga e tuku karere ana ki te whare e tata mai ana. Arā, ka hangaia ēnei i te wāhi e hiahiatia ana, ā, ka pā noa ki ngā pūtau e tata ana . Kāore e haereere puta noa i te tinana mā te toto. Nō reira, he poto noa iho te roa o tā rātou mahi. Ka hangaia ēnei Prostaglandin mai i tētahi waikawa ngako e kiia nei ko te waikawa arachidonic, e kitea ana i roto i ngā pūtau o tō tātou tinana.
He aha te mahi matua a ngā prostaglandin?
He maha ngā momo prostaglandin. Waihoki, he maha ngā momo kaiwhakawhiwhi e herea ana e rātou. Nō reira, he rerekē ā rātou mahi. Kei te okana, te kiko e pāngia ana e rātou, me ngā hiahia o te tinana i taua wā.
Anei ētahi o ngā mahi matua a rātou:
| Tukanga | Te mahi a ngā prostaglandin |
|---|---|
| Te whakaora i te patunga | Ina pāngia he whara, ka kohia ngā pereti toto, ā, ka whakahaeretia kia hanga he toto totoka hei aukati i te toto. |
| mumura | Hei tiaki i ngā kiko kua pakaru, ka piki ake te rere o te toto ki te wāhi, ka pupuhi, ka whero, ka mamae hoki. |
| Mamae me te kirika | Ka whakaoho i ngā io e rongo ana i te mamae. Ka pā hoki ki te pokapū whakahaere pāmahana i roto i te roro, ka puta te kirika. |
| Pūnaha whakaputa uri wahine | Ka āwhina i te kōpū kia kōpiri me te whakataka i te arai o te kōpū (endometrium) i te wā paheketanga. Ka āwhina i te whakatuwheratanga o te cervix me te kōpiri i te kōpū i te wā whānau. |
| Te toto totoka | Mā te whakanui i te toto, te vasoconstriction rānei, ka āwhina i te whakahaere i te toto toto. |
| Puku | Ka whakaiti i te tukunga waikawa o te puku, ka whakamātotoru hoki i te arai hūpē e tiaki ana i te pakitara o te puku. |
| Pūnaha manawa | Ka whaiti ngā ara manawa (ka whakawhāitihia te hau) ka whānuitia rānei (ka whakanuia te hau). |
Kia mārama tātou ki tēnei mā te whakamahi i tētahi tauira tūturu.
Whakaarohia kei roto koe i te kīhini e tapatapahi ana i ngā huawhenua, ā, ka motuhia tō maihao e te maripi. Āue! He aha te mea ka tupu inaianei? Koinei te mahi a ngā prostaglandin:
1. Te aukati i te toto: Ka tukuna tonutia ngā prostaglandin mai i te kiko whara o te maihao. Ka tohu ēnei i ngā pereti toto kia "haere mai ki konei kia piri tahi hei hanga i te toto totoka." Ka hiritia e taua toto totoka te patunga, ā, ka mutu te totoka. I taua wā anō, ka āwhina hoki ngā prostaglandin ki te whakawhāiti i ngā oko toto i taua wāhi.
2. Mumura: Muri iho, ka uru mai tētahi atu momo prostaglandin ka whakawhanui i ngā oko toto. Ka nui ake te rere o te toto. Koinei te take ka whero te patunga, ka pupuhi paku . Mā tēnei pupuhi ka ārai i ngā mea pēnei i ngā iroriki ka uru pea ki te patunga kia kore e tae atu ki ētahi atu wāhanga o te tinana.
3. Kawemai o ngā pūtau haumarutanga:Ka tukuna e ēnei prostaglandin tētahi atu tohu ki ngā pūtau tiaki o tō tātou tinana, arā, ngā pūtau toto mā. Ko ngā phagocytes, inā koa, ka aro atu ki tēnei tohu, ā, ka "kai" me te horoi i ngā iroriki me ngā pūtau pakaru kua uru mai mā roto i te patunga.
4. Mamae: Haunga ēnei mea katoa, ka nui ake te aro o ngā pito io o reira nā ngā Prostaglandins. Koia tātou ka rongo ai i te mamae . E mea ana tēnei mamae ki a tātou, "Kua whara tō matihao, kia tupato."
5. I muri i te ora: Kia ora rawa te patunga, ka uru mai tētahi atu momo prostaglandin ka whakarewa i te toto totoka i hangaia i mua, nā te mea kāore e hiahiatia ana.
Kua kite koe i te uaua o tētahi pūnaha e mahi ana i roto i ō tātou tinana ahakoa he whara iti noa iho? He mahi nui tā ngā prostaglandins ki te whakarite i ēnei mea katoa.
Nā, he pai, he kino rānei ngā prostaglandin?
He pātai tino nui tēnei. He mea nui, he mea taiao hoki ngā prostaglandin mō ō tātou tinana. He mea nui ēnei mō te whakaora i ngā patunga, te tiaki i ngā huakita, me te whakahaere i te huringa paheketanga. Ko te mumura, he tukanga e kiia nei ko te mumura, he huarahi mō te tinana ki te tiaki i a ia anō.
Engari ka puta te raruraru ina tīmata te tinana ki te hanga i ngā prostaglandin nui atu i tana e hiahia ana . Koinā te wā ka tīmata ai ngā raruraru.
Hei tauira, e hiahiatia ana ngā prostaglandin kia taea ai te whakawhāiti i te kōpū i te wā paheketanga. Heoi, ki te nui rawa te whakaputanga, ka whakawhāiti nui te kōpū, ka mamae hoki. Koinei te mea e kiia nei e tātou ko ngā mamae o te paheketanga . I ētahi wā ka puta hoki i tēnei āhuatanga te toto nui (menorrhagia).
Waihoki, ko te take e mamae tonu ai, e pupuhi ai hoki ngā hononga o te hunga e pāngia ana e ngā mate pūmau pēnei i te rumatiki, he mea kei te teitei tonu ēnei taumata prostaglandin.
Me pēhea te whakamahi i ngā prostaglandin i roto i te rongoā?
Kia mārama te mahi a ngā prostaglandin, ka whakamahia e ngā tākuta mō ngā momo maimoatanga. Ka whakamahia hoki e rātou ngā rongoā hei aukati i tā rātou mahi.
Ngā Prostaglandin Hangaia
Ko ngā rongoā e rite ana ki ngā prostaglandin, i hangaia i roto i te taiwhanga, e whakamahia ana hei rongoā i ngā momo mate hauora.
- Mō te whānautanga: Ko ngā whaea hapū kua roa te whānautanga ka hoatu he rongoā pēnei i te Dinoprostone hei whakawhānui i te kaki me te whakawhāiti i te kōpū.
- Glaucoma: Ka whakamahia ngā pata kanohi pēnei i a Travoprost hei rongoā i te glaucoma, he āhuatanga e piki ake ai te pēhanga o te kanohi.
- Mō te ngoikore o te ira tāne (Te ngoikore o te ure):Ko te Alprostadil, he rongoā e whakawhanui ana i ngā oko toto, e whakamahia ana hei rongoā mō tēnei mate.
- Ngā Mate Puku: Ka taea e ētahi rongoā whakamamae te kino i te arai o te puku mēnā ka tangohia tonutia. Hei ārai i tēnei, ka hoatu he rongoā pēnei i te Misoprostol, e whakaiti ana i te waikawa o te puku.
Ngā rongoā e aukati ana i te mahi a te prostaglandin
He maha ngā rongoā whakamamae mamae e whakamahia ana e tātou, e tūtakihia ana hoki e tātou, e aukati ana i te hanga o ngā prostaglandin. Ko tēnei rōpū rongoā e kiia ana ko ngā rongoā anti-inflammatory kore-steroidal , ko ngā NSAID rānei hei whakarapopototanga.
Ko ngā rongoā mamae pēnei i te Ibuprofen, te Naproxen, te Diclofenac, te Mefenamic Acid e whakamahia ana e koe, nō tēnei rōpū katoa (NSAID). Ina tangohia ēnei hei rongoā mō te mamae o te paheketanga, te ānini, me te mamae o ngā hononga, ka whakaitihia te mamae nā te mea ka aukatihia e ēnei rongoā te hanga o ngā prostaglandin.
He aha ngā raruraru ka pā ki ngā prostaglandin?
I ētahi wā, he nui rawa ngā prostaglandin e hangaia ana e ō tātou tinana, kāore rānei i te rawaka. I ngā āhuatanga e rua, ka puta pea ngā raruraru hauora.
Ngā āhuatanga ka puta ina piki ake ngā prostaglandin:
- Mamae mau tonu: Ka pā mai pea te mamae tonu i roto i te tinana.
- Te tairongo nui ki te mamae: Te mamae nui ahakoa i te mea iti rawa.
- Te mamae o te paheketanga (Dysmenorrhea): Ko te mamae o te paheketanga i kōrerohia e tātou i mua ake nei.
- Te toto nui o te paheketanga.
- Kua kitea e ngā rangahau he whai wāhi anō hoki ngā taumata teitei o ngā prostaglandin ki te tipu o ētahi momo mate pukupuku .
Ina kore e ranea ngā prostaglandin:
Kāore tēnei e pā ana ki tētahi mate pūmau. Heoi, tera pea ētahi wā kāore e ranea te nui o ngā prostaglandin e hiahiatia ana hei whakaora i te patunga. Waihoki, i ngā wā kāore e nui ngā prostaglandin e hangaia ana e te tinana hei tīmata i te whānautanga, ka hoatu e ngā tākuta he prostaglandin hangai mai i waho.
Āhea koe me toro atu ki te tākuta?
Ki te mamae tonu, ki te pupuhi rānei tō tinana, me toro atu ki tō tākuta , me kōrero ki a ia mō tēnei. He maha ngā take mō tēnei, engari ko te kore taurite o te mahi a ngā prostaglandin te tino take.
Tērā tētahi mea nui hei kōrero mō te mamae o te paheketanga.
Mena he tino kino te mamae o tō paheketanga, ā, kāore e taea te whakahaere mā te whakamahi i ngā rongoā mamae kore-tohu (NSAID), kaua e whakakorea noa iho he "mea e pā ana ki ngā kōtiro." I ētahi wā ka puta tēnei mamae nui i te endometriosis , i teTērā pea nā tētahi mate hauora kei raro i te maru, pērā i te fibroids uterine. Nō reira, me kōrero koe ki tō tākuta mō tēnei mea, kia whiwhi ai koe i ngā tohutohu me ngā maimoatanga e tika ana.
He matū whakamiharo ngā prostaglandin e mahi puku ana engari he kaha i roto i ō tātou tinana. Ahakoa he mea nui ēnei mō tō tātou oranga, ina pakaru tō rātou taurite, ka pā kino ki te kounga o ō tātou oranga. Nō reira, kia aro ki tō tinana. Mena kei te pāngia koe e te mamae tonu, e ngā tohu rerekē rānei, kaua e mangere ki te rapu tohutohu hauora.
Karere Tangohia ki te Kāinga
- He matū rite ki ngā homoni ngā prostaglandin e whakaputaina ana i roto i ō tātou tinana, i ngā wāhi e hiahiatia ana.
- He maha ngā tukanga e whai wāhi tika ana ēnei ki te mamae, te pupuhi, te kirika, te toto totoka, me te paheketanga.
- Ahakoa he mea nui ēnei mō te tinana, ka taea e te nui rawa te whakararuraru i ngā raruraru pērā i te mamae mau tonu me ngā mamae nui o te paheketanga.
- Ko ngā rongoā mamae (NSAID) pērā i te ibuprofen ka aukati i te hanga o ngā prostaglandin.
- Mena he mamae nui tō te paheketanga, kāore e taea te whakahaere, he mamae roa rānei, kaua e warewarehia, engari me toro atu ki tō tākuta tonu.
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