Kodi mwamvapo za puloteni yachilendo iyi m'magazi mwanu? (Cryoglobulinemia) Tiyeni tikambirane za iyo!

Nthawi zina zinthu zimachitika m'thupi mwathu zomwe sitikuyembekezera, sichoncho? Lero tikambirana za vuto lomwe ndi lachilendo pang'ono, koma ndilofunika kudziwa. Izi zimatchedwa cryoglobulinemia. Dzinalo lingamveke ngati lovuta pang'ono, koma musadandaule, tiyeni tifotokoze mwachidule.

Kodi cryoglobulinemia ndi chiyani? Mwachidule...

Mwachidule, cryoglobulinemia ndi vuto limene mapuloteni ena osazolowereka m'magazi mwanu, otchedwa cryoglobulin, amauma, amasonkhana pamodzi, ndikupanga magazi kuundana akamazizira. Taganizirani ngati mafuta a kokonati omwe amaundana mukawaika m'madzi ozizira. Koma izi zimachitika m'magazi mwathu. Vutoli kwenikweni ndi mtundu wa vasculitis. Ndi kutupa, monga kutupa, kwa mitsempha yanu yamagazi, machubu ang'onoang'ono omwe amanyamula magazi m'thupi lanu lonse. Mitsempha yamagazi iyi ikatupa, kuyenda kwa magazi kumatha kusokonezeka. Nanga chimachitika ndi chiyani? Khungu lanu, mitsempha, mafupa, minofu, ndipo chofunika kwambiri, ziwalo zamkati monga impso zanu, zimatha kuwonongeka. Izi nthawi zina zimatchedwa cryoglobulinemic vasculitis.

Kodi pali mitundu ya cryoglobulinemia?

Inde, mapuloteni awa otchedwa cryoglobulins nawonso ndi mtundu wa antibody. Kutengera mtundu wa antibody wopangidwa ndi thupi lathu, cryoglobulinemia ikhoza kugawidwa m'mitundu itatu ikuluikulu:

• Mtundu Woyamba wa Cryoglobulinemia: Izi nthawi zambiri zimayambitsidwa ndi khansa yokhudzana ndi magazi anu kapena khansa yokhudzana ndi chitetezo chamthupi chanu.
• Mtundu wa II Cryoglobulinemia ndi Mtundu wa III Cryoglobulinemia: Mitundu iwiriyi imapezeka nthawi zambiri ndi matenda osatha (kutanthauza, a nthawi yayitali) otupa. Mwachitsanzo, imatha kupezeka mwa anthu omwe ali ndi matenda odziteteza okha . Makamaka, Mtundu wa II Cryoglobulinemia ndi wofala kwambiri mwa anthu omwe ali ndi kachilombo ka Hepatitis C (HCV). Mitundu iwiriyi imaphatikizidwa ndipo imatchedwa Mixed Cryoglobulinemia.

Kodi vutoli ndi lofala bwanji?

Cryoglobulinemia kwenikweni ndi vuto losowa kwambiri.Koma ofufuza sakudziwabe kuti ndi anthu angati omwe ali ndi vutoli. Chifukwa chakuti anthu ena akhoza kukhala ndi ma cryoglobulins ochepa m'magazi awo koma osawonetsa zizindikiro zilizonse, ofufuza akuti vutoli limakhudza pafupifupi munthu mmodzi pa anthu miliyoni padziko lonse lapansi.

Kodi zizindikiro zake ndi ziti? Kodi aliyense amakumana ndi zizindikiro?

Ayi, si aliyense amene ali ndi cryoglobulinemia amene ali ndi zizindikiro. Anthu ena sangazindikire chilichonse. Koma zizindikiro zikaonekera, chizindikiro chofala kwambiri ndi kutupa pakhungu kotchedwa purpura. Izi zimawoneka ngati mawanga ofiira kapena mabala ofiirira m'miyendo ya m'munsi. Muthanso kumva kutopa ndikumva kupweteka m'mafupa. Zizindikiro zina zingachitikenso. Izi zikuphatikizapo:

• Mitsempha ya magazi m'manja ndi/kapena m'mapazi ikakumana ndi kutentha kozizira, imachepa, zomwe zimapangitsa kuti isinthe kukhala yabuluu. Izi zimatchedwa Raynaud's phenomenon .
• Kuchepetsa thupi .
• Kuthamanga kwa magazi (BP).
• Kutupa, makamaka m'mabondo ndi m'miyendo (Edema).
• Zilonda za pakhungu ndipo nthawi zina kufa kwa minofu (gangrene).
• Chiwindi chokulirapo (Hepatomegaly) kapena ndulu yokulirapo (Splenomegaly).
• Kusanza , kumva kuwawa, kapena kufooka m'miyendo.
• Kuwonongeka kwa impso.

Taganizirani izi, izi sizikutanthauza kuti miyendo yanu yayamba kuoneka yabuluu chifukwa cha kuzizira. Izi zitha kukhala chizindikiro cha vuto lalikulu m'thupi lanu. Ndicho chifukwa chake ndikofunikira kudziwa zinthu ngati izi.

Kodi zifukwa za cryoglobulinemia ndi ziti?

Ofufuza sakudziwabe chomwe chimayambitsa cryoglobulinemia. Koma monga tafotokozera kale, ndi mtundu wa matenda odziteteza okha otchedwa vasculitis, omwe ndi kutupa kwa mitsempha yamagazi. Matenda odziteteza okha ndi pamene chitetezo cha mthupi lanu, chitetezo cha thupi chomwe chimakutetezani ku matenda, chikuukira minofu yanu yathanzi molakwika. Pali zinthu zingapo zomwe zingayambitse izi:

• Majini: Ngati wina m'banjamo ali ndi vutoli, likhoza kukhudzidwa.
• Mitundu ina ya mankhwala: Si mankhwala onse, koma ena.
• Matenda ndi mavairasi: Makamaka matenda opatsirana ndi mavairasi.
• Zinthu zachilengedwe: Zinthu zina zomwe zili m'malo otizungulira.

Nthawi zina cryoglobulinemia imadzichitikira yokha popanda chifukwa chodziwika bwino (izi zimatchedwa idiopathic), koma nthawi zambiri imachitika limodzi ndi matenda ena. Ena mwa matenda amenewa ndi awa:

• Matenda a chiwindi cha mtundu wa C: Ichi ndiye chiwalo chachikulu komanso chodziwika bwino.
• Matenda a maselo a m'magazi: Mwachitsanzo, matenda a khansa monga lymphoma ndi multiple myeloma.
• Matenda a minofu yolumikizana: Chitsanzo ndi lupus.

Ndani amene ali pachiwopsezo chachikulu cha izi?

Matenda a cryoglobulinemia amaoneka kuti amakhudza akazi kwambiri kuposa amuna, ndipo amapezeka kwambiri mwa anthu azaka zopitirira 50.

Kodi mavuto angachitike ngati sakuthandizidwa bwino?

Inde, ndithudi. Ngati cryoglobulinemia sichitha kuchiritsidwa bwino, ikhoza kuwononga khungu lanu, minofu yanu, ndi ziwalo zamkati kwamuyaya. Zina mwa mavuto akuluakulu omwe angachitike ndi awa:

• Matenda a pakhungu kapena mabala osachiritsa.
• Kufa kwa khungu (necrosis).
• Kulephera kwa impso.
• Kulephera kwa chiwindi.

Izi ndi matenda oopsa kwambiri, ndichifukwa chake ndikofunikira kuzindikira ndi kuchiza matendawa mwachangu.

Kodi madokotala amazindikira bwanji vutoli?

Mukapita kwa dokotala, iye adzakufunsani kaye za mbiri yanu yachipatala ndikukuyesani thupi. Kenako, adzayitanitsa mayeso apadera a magazi kuti aone ngati muli ndi ma cryoglobulin m'magazi mwanu. Kuyezetsa magazi kumeneku kungakuuzeninso mtundu wa cryoglobulin womwe muli nawo. Izi nthawi zina zingathandize kudziwa chomwe chayambitsa vuto lanu komanso momwe mungachiritsire. Kuwonjezera pa kuyezetsa magazi kumeneku, dokotala wanu angafune mayeso ena angapo kuti atsimikizire matendawa ndikumvetsetsa vutoli:

• Kuyesa mkodzo (Kusanthula mkodzo).
• X-ray ya pachifuwa.
• Kujambula kwa CT (CT scan).
• Angiogram (yomwe imayang'ana momwe mitsempha yamagazi ilili).
• Mayeso a MRA (magnetic resonance angiogram) kapena mayeso a CT angiogram (CT angiogram).
• Kuyesa koyendetsa mitsempha.
• Kuyesa kwa electromyography (EMG) (onani momwe minofu imagwirira ntchito).
• Kujambula (kutenga chidutswa chaching'ono cha minofu, mwina kuchokera pakhungu kapena impso, kuti chikayesedwe).

Kodi izi zimachiritsidwa bwanji?

Chithandizo cha cryoglobulinemia chimadalira ziwalo zomwe zakhudzidwa, kuchuluka kwa kuwonongeka, komanso ngati muli ndi matenda ena.Ndikofunikira kuchiza matenda ena omwe angagwirizane ndi cryoglobulinemia, monga chiwindi cha chiwindi C, komanso matenda ena omwe angagwirizane ndi vutoli. Izi zili choncho chifukwa kuchiza matenda enawo nthawi zina kungathandize kuchepetsa zizindikiro za cryoglobulinemia. Ngati zizindikiro zanu sizili zazikulu, dokotala wanu angakulangizeni mankhwala ochepetsa ululu omwe mumagwiritsa ntchito (monga NSAIDs) ndikukulangizani kuti mupewe kutentha kwambiri . Angakulimbikitseninso kuti muyezedwe nthawi zonse kuti muwone momwe mulili. Pa milandu yofatsa, kapena yapakati kapena yoopsa, chithandizo chingakhale chosiyana pang'ono:

• Mankhwala oletsa chitetezo chamthupi: Uwu ndiye mankhwala akuluakulu. Mankhwala a corticosteroids, monga prednisone, nthawi zina amaperekedwa pamodzi ndi mankhwala ena. Izi zimatengera chiwalo chomwe chakhudzidwa ndi kukula kwa kuwonongeka.
• Mankhwala oletsa mavairasi: Ngati dokotala wanu akupeza kuti muli ndi vuto lina, monga chiwindi cha mtundu wa C, angakulangizeni kuti mulandire chithandizo choletsa mavairasi. Angakutumizireninso kwa katswiri wa chiwindi (hepatologist).
• Biologics: Rituximab ndi mankhwala ofala kwambiri a cryoglobulinemia. Biologics ndi mapuloteni ovuta opangidwa kuchokera ku zamoyo zomwe zimafuna mbali zinazake za chitetezo cha mthupi kuti zithetse kutupa.
• Plasmapheresis: Iyi ndi njira ina yochizira. Imagwira ntchito pochepetsa kuchuluka kwa ma cryoglobulins m'magazi anu. Munjira imeneyi, ma cryoglobulins amachotsedwa mu plasma yanu (gawo lamadzimadzi la magazi anu). Izi zimathandiza kuti ma cryoglobulins asatseke mitsempha yanu, kuletsa kuyenda kwa magazi komanso kuchepetsa kuwonongeka kwa ziwalo.

Tidziwenso za zotsatirapo zake komanso mavuto omwe amabwera chifukwa cha chithandizo.

Mankhwala omwe madokotala amapereka pochiza cryoglobulinemia akhoza kukhala ndi zotsatirapo zina zoyipa. Zazikulu ndi kufooka kwa mafupa komanso kuchepa kwa mphamvu ya thupi yolimbana ndi matenda. Chifukwa chake, ndikofunikira kwambiri kupita kwa dokotala nthawi zonse kuti akafufuze. Kenako, dokotala wanu akhoza kukupatsani mankhwala ena kuti athetse zotsatirapo zoyipazi. Ndikofunikanso kudziteteza ku matenda. Chifukwa chake, lankhulani ndi dokotala wanu za katemera omwe angachepetse chiopsezo cha matenda.

Kodi pali njira yopewera vutoli?

Popeza chifukwa chenicheni cha cryoglobulinemia sichikudziwika, palibe njira yeniyeni yopewera izi. Komabe, kupewa kuzizira kungathandize .Zingathandize kuchepetsa zizindikiro zina, monga matenda a Raynaud. Ndikofunikanso kwambiri kuyezetsa matenda a Hepatitis C ndikupeza chithandizo ngati muli nawo.

Kodi munthu amene ali ndi matendawa ayenera kukhala ndi chiyembekezo chotani?

Kawonedwe kanu, ndiko kuti, momwe matendawa adzawonekere, kamadalira zinthu zingapo:

• Matenda ena omwe muli nawo.
• Kuchuluka kwa kuwonongeka kwa ziwalo zanu.
• Momwe mumayankhira bwino mukalandira chithandizo.

Komanso, kuopsa kwa matendawa kumasiyana malinga ndi munthu aliyense. Anthu ena sangakhale ndi zizindikiro zilizonse, kapena vuto lawo likhoza kukhala lochepa kwambiri moti sangafunike chithandizo. Kwa anthu omwe ali ndi matenda ochepa kapena ovuta, kuzindikira msanga ndi kulandira chithandizo kungathandize kuchepetsa zizindikiro ndikupewa mavuto a nthawi yayitali. Ngati ziwalo zanu sizikuwonongeka kwamuyaya, chiyembekezo chimakhala chabwino kwambiri.

Kodi ndimadzisamalira bwanji? Ndani angandithandize?

Chinthu chabwino kwambiri chomwe mungachite ndikugwira ntchito limodzi ndi gulu lanu lachipatala. Kutengera ndi ziwalo zomwe cryoglobulinemia yanu yakhudza, mungafunike kugwira ntchito ndi gulu la madokotala osiyanasiyana. Izi zingaphatikizepo:

• Madokotala omwe ndi akatswiri pa matenda a mafupa ndi minofu yolumikizana (Rheumatologists).
• Madokotala a khungu.
• Akatswiri a zamagazi.
• Madokotala omwe ndi akatswiri pa matenda a impso (Nephrologists).
• Akatswiri a mtima.
• Akatswiri a za ubongo.
• Akatswiri a matenda a chiwindi.

Dziwani bwino gulu lanu lachipatala. Lankhulani nokha. Funsani mafunso. Ngati muli ndi nkhawa iliyonse yokhudza dongosolo lanu la chithandizo, kambiranani. Madokotala anu alipo kuti akumvetsereni ndikuonetsetsa kuti mukumvetsa bwino chilichonse chomwe chikukhudza thanzi lanu ndi chisamaliro chanu.

Kodi ndiyenera kupita kwa dokotala liti?

Ngati muli ndi zizindikiro za cryoglobulinemia, muyenera kupita kuchipatala nthawi yomweyo. Komanso, ngati muli ndi matenda a chiwindi C ndipo zizindikiro zilizonsezi zikuwonekera, pitani kwa dokotala. Ngakhale mutalandira chithandizo chogwira mtima, matendawa nthawi zina amatha kubwereranso (kubwerera m'mbuyo). Ngati mukupeza zizindikiro zatsopano, ngati zizindikiro zomwe muli nazo zikuipiraipira, kapena ngati zizindikiro zanu zabwerera, pitani kwa dokotala. Kupimidwa nthawi zonse ndi kutsatiridwa nthawi zonse ndikofunikira kuti mudziwe kubwereranso msanga ndikupewa mavuto.

Ndi mafunso ati omwe ndiyenera kufunsa dokotala?

Mukapita kwa dokotala, ndi bwino kufunsa mafunso ngati awa:

• Kodi n’chiyani chinandipangitsa kuti ndidwale matendawa?
• Kodi mumalimbikitsa chithandizo chanji?
• Ndi zotsatirapo ziti za chithandizo zomwe ndiyenera kuda nkhawa nazo?
• Ndi mavuto ati omwe angachitike chifukwa cha vutoli?
• Kodi ndingatani kuti matendawa asabwererenso?

Zinthu zofunika kwambiri zomwe tiyenera kukumbukira (Uthenga Wopita Nawo Kunyumba)

Kukhala ndi cryoglobulinemia nthawi zina kungakhale kovuta. Zizindikiro ndi zotsatirapo za mankhwala zimatha kukhudza kwambiri thanzi lanu la maganizo. Zingakhudzenso mbali zina zambiri za moyo wanu.

Koma kumbukirani kuti simuli nokha. Funsani dokotala wanu kuti akuthandizeni, ndipo pezani magulu othandizira komwe ena omwe akukumana ndi mavuto ofanana angakumane. Kugawana zomwe mwakumana nazo ndi zomwe mukudziwa kungakuthandizeni kukhala ndi cryoglobulinemia. Kudziteteza ku chimfine, kufunafuna upangiri wa dokotala, kusasuta fodya, ndi kudya zakudya zopatsa thanzi ndizofunikira kwambiri.

Ndikukhulupirira kuti izi zikuthandizani. Khalani ndi thanzi labwino!