Kodi dokotala wanu wakuuzani kuti mukayezedwe ndi ANA? Mwina munamva mantha pang'ono komanso mantha pamene ananena zimenezo. Ndi zachilendo kuti mafunso monga "Kodi mayesowa ndi otani?", "Akuyang'ana chiyani?", "Kodi ndidwala kwambiri ngati lipotilo lili ndi kachilombo?" abwere m'maganizo mwanga. Koma musadandaule. Lero, tikambirana m'njira yosavuta komanso yochezeka za zomwe mayesowa a ANA ali, chifukwa chake amachitika, komanso momwe tingatanthauzire lipotilo.
Choyamba, tiyeni tiwone tanthauzo la ANA iyi.
Kuti timvetse izi, choyamba tiyenera kudziwa pang'ono za chitetezo cha mthupi lathu, chitetezo cha mthupi . Tangoganizani kuti thupi lathu lili ngati dziko. Ndiye chitetezo cha mthupi ichi ndi gulu lankhondo m'dziko limenelo. Adani akunja, monga mavairasi ndi mabakiteriya , akalowa m'thupi, gulu lankhondoli limawazindikira, kuwaukira, ndi kuwawononga.
Ma antibodies ndi gulu lapadera la asilikali mu gulu lankhondo ili. Ali ngati positi ya "KUFUNIKIRA" ya apolisi. Ntchito yawo ndi kuzindikira mdani amene walowa m'thupi ndikuwapereka ku maselo ena achitetezo.
Koma nthawi zina chitetezo chathu chimalakwitsa pang'ono. M'malo mwa oukira akunja, amachitcha maselo athu athanzi kukhala "adani." Kenako chitetezo chathu chimayamba kuukira maselo athu. Umu ndi momwe timatchulira ma antibodies olakwika omwe amapangidwa motsutsana ndi maselo athu , ma autoantibodies .
Ma Antinuclear Antibodies (ANA) ndi mtundu umodzi wa ma autoantibody. Monga momwe mawu akuti "nuclear" m'dzina lawo akusonyezera, cholinga chawo chachikulu ndi gawo la "ubongo" la maselo athu, "nucleus" . Kuwonjezeka kwa kuchuluka kwa ANA iyi m'magazi ndi chizindikiro chakuti tikhoza kukhala ndi matenda a autoimmune , vuto lomwe thupi lathu likulimbana nalo lokha.
N’chifukwa chiyani dokotala angalimbikitse mayeso a ANA awa?
Ngati dokotala wanu akukayikira kuti muli ndi matenda odziteteza ku matenda enaake chifukwa cha zizindikiro zina zomwe mukukumana nazo (monga kupweteka kosalekeza kwa mafupa , ziphuphu pakhungu, kutopa kwambiri), angakufunseni kuti muyesedwe ndi ANA kuti atsimikizire kapena kuchotsa kuthekera.
Pansipa pali zina mwa matenda akuluakulu omwe mayeso a ANA angathandize kuzindikira.
| Mkhalidwe | Mwachidule... |
|---|---|
| Matenda a Lupus Erythematosus (SLE) - Lupus | Ndi vuto lovuta lomwe lingakhudze ziwalo zosiyanasiyana m'thupi, monga khungu, mafupa, impso, ndi ubongo. |
| Matenda a Sjögren | Matenda omwe amayambitsa makamaka maso ndi pakamwa pouma. |
| Scleroderma | Kukhuthala ndi kuuma kwa khungu ndiye chizindikiro chachikulu, ndipo chingakhudzenso ziwalo zamkati. |
| Dermatomyositis kapena Polymyositis | Matenda omwe amayambitsa kufooka kwa minofu ndi kutupa. |
| Matenda Osakanikirana a Minofu Yolumikizana (MCTD) | Matenda omwe amaphatikiza zizindikiro za matenda angapo, monga lupus ndi scleroderma. |
Kuphatikiza apo, mayeso a ANA angakhale abwino pa matenda ena a khansa.
Kodi mayesowa amachitika bwanji? Kodi akupweteka?
Ndi zophweka kwambiri. Zili ngati mupereka magazi. Namwino kapena dokotala wa phlebotomist amatenga chitsanzo cha magazi kuchokera mumtsempha womwe uli m'dzanja lanu. Sizitenga mphindi imodzi. Kenako amaika bandeji yaying'ono pamalopo. Ndicho chokha. Ndicho chomwe muyenera kuchita.
Kenako, mu labu, katswiri wa matenda adzayang'ana magazi anu pogwiritsa ntchito njira yapadera. Njira yodziwika kwambiri imatchedwa indirect immunofluorescence (IIF) . Izi zimaphatikizapo kupaka magazi anu ndi ANA, yomwe imapangidwa kuti iwalane pogwiritsa ntchito maikulosikopu yapadera. Kenako lipotilo limalembedwa poyang'ana maselo owala.
Kodi mungamvetse bwanji lipoti la mayeso?
Mudzalandira lipoti la mayeso m'masiku ochepa. Likhoza kukhala ndi magawo atatu akuluakulu. Tiyeni timvetse chimodzi ndi chimodzi m'mawu osavuta.
| Gawo lomwe lili mu lipotilo | Kodi zimenezo zikuti chiyani? |
|---|---|
| Kutanthauzira (Kwabwino / Koipa) | Ichi ndi chinthu chofunikira kwambiri. Kaya ANA yapezeka m'magazi mwanu kapena ayi. Ngati yapezeka, idzalembedwa ngati "Yabwino". Kupanda kutero, idzalembedwa ngati "Yoipa". |
| Kuwerenga Titer (kuchuluka) | Ngati mayeso ali ndi kachilombo, chinthu chotsatira choti muwone ndi kuchuluka kwa ma antibodies amenewa omwe alipo. Izi zikuwonetsedwa mu ma ratios monga 1:40, 1:80, 1:160, 1:320. Chiŵerengerocho chikakhala chachikulu, kuchuluka kwa ma antibodies kumakwera. Kuchuluka kwa ma antibodies kukakhala kwakukulu, mwayi wokhala ndi matenda a autoimmune umakwera. |
| Chitsanzo cha Kuwala | Dokotala angapezenso zizindikiro zina kuchokera ku momwe selo limawunikira pansi pa maikulosikopu, kutanthauza "chithunzi". Mwachitsanzo, pali mitundu yosiyanasiyana monga "Homogenous", "Speckled", "Centromere". Mitundu ina ndi yeniyeni ku matenda enaake. Izi ndi zovuta pang'ono, kotero dokotala wanu adzakufotokozerani. |
Kodi muyenera kuchita mantha ngati mwapezeka ndi kachilombo ka ANA?
Chofunika kwambiri ndi ichi. Kungoti mayeso a ANA ndi abwino sizitanthauza kuti muli ndi matenda odziteteza okha nthawi zonse. Kumbukirani izi.
Ndipotu, anthu atatu okha mwa anthu 10 athanzi omwe alibe matenda ndi omwe adzayezedwe ndi ANA. Zimenezo n'zachibadwa.
Pakhoza kukhala zifukwa zina zomwe mayeso a ANA alili abwino.
- Mukakhala ndi matenda ngati chimfine chofala.
- Chifukwa cha mankhwala ena omwe mumamwa.
- ANA nthawi zina imatha kukhala ndi thanzi labwino ikakula.
Choncho, ngati mayeso anu a ANA ali ndi kachilombo, dokotala wanu adzangoganizira ngati gawo limodzi la funsoli. Adzaganizira zizindikiro zanu, zotsatira zina za mayeso, ndi lipoti ili la ANA, kenako adzafika pamapeto pake. Angalimbikitsenso mayeso ena enieni a magazi (monga anti-dsDNA, anti-Sm) kuti athandize kuzindikira vutoli.
Kotero, mayeso a ANA ndi chida chamtengo wapatali kwambiri chomwe chimathandiza madokotala kuzindikira matenda odziteteza okha . Koma musachite mantha nokha mutaona lipotilo. Lankhulani ndi dokotala wanu za mafunso kapena kukayikira kulikonse komwe muli nako. Iye adzakufotokozerani zonse ndikukupatsani malangizo ofunikira.
Uthenga Wopita Nawo Kunyumba
- Mayeso a ANA ndi mayeso osavuta a magazi omwe amathandiza kuzindikira matenda odziteteza ku matenda a autoimmune .
- Izi zikutanthauza mtundu wa antibody womwe umapangidwa motsutsana ndi maselo a thupi lathu.
- Kungoti mayesowo ndi "olondola" sizikutanthauza kuti muli ndi matendawa. Anthu athanzi amathanso kupezeka ndi matendawa.
- Magawo onse atatu a lipotilo ndi ofunikira: zotsatira zake (Zabwino/Zoipa), kuchuluka kwa ma antibodies (Titer), ndi mawonekedwe owala (Pattern).
- Nthawi zonse kambiranani ndi dokotala wanu za lipoti lanu la mayeso ndi zomwe mungachite kenako . Musapange zisankho nokha kapena kuchita mantha mosayenera.
💬 Comments (0)
Palibe ndemanga zomwe zatumizidwa pano. Onjezani ndemanga yanu pano koyamba.
Onjezani ndemanga yanu