Zomwe zapezeka posachedwapa pa khansa ya m'mawere yowonjezereka - Tiyeni tikambirane

Ngati inu kapena munthu amene mumamudziwa akulimbana ndi khansa ya m'mawere yomwe yakula kwambiri, zingakhale zolimbikitsa kwambiri kukhala ndi chidziwitso chokhudza zinthu zatsopano ndi zomwe zapezeka. Asayansi ndi madokotala nthawi zonse amayesetsa kumvetsetsa matendawa bwino ndikupeza njira zatsopano komanso zothandiza. Tiyeni tiwone chiyembekezo chatsopanochi.

Mankhwala atsopano ovomerezeka

Mankhwala angapo atsopano ayambitsidwa kale omwe awonetsa zotsatira zabwino kwambiri pa khansa ya m'mawere yomwe yakula. Ena mwa mankhwalawa amagwira ntchito poyang'ana mapuloteni enaake omwe amayang'anira kukula kwa maselo a khansa.

Mwachidule, mitundu ina ya khansa ya m'mawere imakhudzidwa ndi mahomoni m'thupi kuti ikule. Timatcha khansa ya "hormone-receptor positive". Komanso, maselo ena a khansa alibe puloteni yotchedwa `HER2` pamwamba pawo. Izi zimatchedwa khansa ya `HER2` negative. Ngati muli ndi khansa yamtunduwu, mankhwala atsopano angakhale njira yabwino kwa inu.

Tiyeni tiwone zina mwa mankhwala atsopanowa patebulo ili m'munsimu.

Ziyembekezo zatsopano zomwe zidakali mu gawo lofufuza

Kuwonjezera pa mankhwala ovomerezeka omwe alipo panopa, palinso mankhwala ena ambiri abwino omwe akufufuzidwa. Ngakhale kuti awa sakugwiritsidwa ntchito kawirikawiri, akhoza kukhala opindulitsa kwambiri mtsogolomu.

Zoletsa za PARP

Mankhwalawa amagwira ntchito poletsa mphamvu ya maselo a khansa yodzikonzera okha (kukonza DNA). Apezeka kuti ndi othandiza kwambiri kwa anthu omwe ali ndi kusintha kwa majini a BRCA1 kapena BRCA2, omwe amalumikizidwa ndi khansa ya m'mawere.

Zoletsa za Tyrosine Kinase

Awa ndi mankhwala omwe amaletsa ma enzyme omwe amathandiza maselo a khansa kukula. Lapatinib (Tykerb) yavomerezedwa kale kuti igwiritsidwe ntchito pa khansa ya HER2-positive. Mankhwala ena, Neratinib, awonetsedwa mu kafukufuku watsopano kuti athandize odwala kukhala ndi moyo wautali akapatsidwa mankhwala a chemotherapy.

Mankhwala ena a HER2 omwe amathandizidwa kwambiri

Pafupifupi munthu m'modzi mwa anthu asanu omwe ali ndi khansa ya m'mawere ali ndi puloteni yochuluka yotchedwa HER2, yomwe imathandiza kukula kwa maselo a khansa ya m'mawere. Mankhwala omwe amalimbana ndi puloteni iyi akupangidwa tsiku lililonse. Mwachitsanzo, mankhwala a Margetuximab awonetsa zotsatira zabwino pakuchepa kwa zotupa, ndipo mankhwala a ONT-380 awonetsa kuti ali ndi chiyembekezo chochiza khansa ya m'mawere popanda zotsatirapo zoyipa zambiri.

Chithandizo china cha chitetezo chamthupi

Mankhwalawa amagwira ntchito polimbikitsa chitetezo chathu chamthupi kuti chizilimbana ndi khansa. Mankhwala a `Pembrolizumab` awonetsa zotsatira zabwino m'mayesero azachipatala, makamaka ngati chithandizo cha khansa ya m'mawere ya `Triple-Negative` yoopsa kwambiri.

Kumvetsetsa kwatsopano momwe khansa imafalikira

Pamodzi ndi mankhwala atsopanowa, asayansi akupezanso zinthu zatsopano zokhudza momwe khansa imafalikira m'thupi lonse (metastasis). Kumvetsetsa kumeneku n'kofunika kwambiri pa chithandizo chamtsogolo.

Tangoganizani, tinkaganiza kuti khansa imafalikira ngati msilikali wochokera ku gulu lankhondo amene akuthawa n’kukamanga msasa kumalo ena. Izi zikutanthauza kuti, selo limodzi la khansa limayenda m’magazi n’kupita ku chiwalo china, monga chiwindi kapena mapapo.

Kupeza kumeneku n'kofunika kwambiri chifukwa, tikadziwa bwino momwe khansa imachitira, zidzakhala zosavuta kwa asayansi kupanga njira zina zochizira zomwe zingalepheretse magulu amenewo. Izi zikutanthauza kuti, kuletsa gulu kuyenda kungakhale kothandiza kwambiri kuposa kuletsa selo limodzi.

Kodi mungathandize bwanji paulendowu?

Ndi zinthu zatsopanozi, inunso mungakhale ndi mwayi wothandiza pankhondoyi mwanjira ina.

Chofunika kwambiri ndikulankhula ndi dokotala wanu. Funsani kuti, "Kodi pali mankhwala atsopano kapena mayesero azachipatala m'dziko lathu omwe angakhale oyenera kwa ine?" Mayeso azachipatala ndi maphunziro omwe amawunikidwa mosamala omwe amayesa kugwira ntchito ndi chitetezo cha mankhwala atsopano asanaperekedwe kwa anthu onse.

Dokotala wanu adzatha kufotokoza ubwino, zoopsa, ndi ziyembekezo zotenga nawo mbali mu mayeso otere. Ndikofunikira kufunsa dokotala wanu musanapange chisankho chilichonse.

Komanso, yang'anani magulu othandizira odwala khansa. Angakupatseni chithandizo chamaganizo ndi chidziwitso chatsopano. Kumbukirani, simuli nokha paulendowu.