Kodi mukumva kufooka? Kodi miyendo yanu ikunjenjemera? Tiyeni tiphunzire za CIDP (Chronic Inflammatory Demyelinating Polyneuropathy)!

Kodi nthawi zina mumamva kutopa kwambiri, manja ndi miyendo yanu yachita dzanzi, kapena mukumva kuwawa? Nthawi zina simungasamale kwambiri zinthuzi. Komabe, nthawi zina, zizindikirozi zitha kukhala chizindikiro cha vuto lalikulu. Chimodzi mwa zinthu zachilendo koma zofunika kuzidziwa ndi CIDP (Chronic Inflammatory Demyelinating Polyneuropathy) . Ngakhale dzinali lingawoneke lalitali pang'ono, tiyeni tipitirizebe kulimvetsa.

Kodi CIDP (Chronic Inflammatory Demyelinating Polyneuropathy) ndi chiyani?

Ngakhale dzinali lingawoneke lovuta pang'ono, ngati tilongosola tanthauzo lake, titha kumvetsetsa bwino matendawa.

• Matenda Osatha: Izi zikutanthauza "kwanthawi yayitali." Izi zikutanthauza kuti CIDP siibwera mwadzidzidzi ndipo imachira mwachangu. Imakula pang'onopang'ono, kwa milungu yosachepera eyiti. Nthawi zina zizindikiro zimatha kenako zimabwereranso miyezi ingapo kapena zaka zingapo pambuyo pake. Zili ngati vuto lobwerezabwereza.

• Kutupa: Izi zikutanthauza "kutupa" . Tikavulala kwinakwake m'thupi lathu, limatupa ndipo limakhala lofiira, sichoncho? Ndicho chimene chili. Koma mu CIDP, kutupa kumeneku kumachitika chifukwa cha vuto linalake m'thupi lathu. Mwachidule, asilikali omwe akuyenera kuteteza thupi lathu amayamba kuukira mitsempha yathu mwangozi. Izi zimatchedwa "Autoimmune Attack" . Kutupa kwakukulu komwe kumachitika chifukwa cha izi kumawononga mitsempha yathu ya m'mphepete . Mitsempha iyi ya m'mphepete ndi mitsempha yomwe imachokera ku ubongo ndi msana.

• Kuchotsa myelin: Ili ndi liwu lozama pang'ono. Ma neuron athu ali ndi chophimba choteteza kuzungulira iwo. Ali ngati chophimba cha pulasitiki chozungulira waya wamagetsi. Chophimba ichi chimatchedwa `(Myelin Sheath)` . Chophimba cha myelin ichi ndi chomwe chimalola mauthenga a mitsempha kuyenda mwachangu komanso molondola. `(Kuchotsa myelin)` kumatanthauza kuti chophimba cha myelin chimawonongeka kapena kuwonongeka. Kenako, monga momwe pulasitiki yomwe ili pa waya imachotsedwera, kutuluka kwa magetsi, ndi mauthenga a mitsempha sizimayenda bwino.

• Polyneuropathy: "Poly" amatanthauza "ambiri." "Neuropathic" amatanthauza kuwonongeka kwa mitsempha. Polyneuropathy amatanthauza kuwonongeka kwa mitsempha yambiri ya m'thupi nthawi imodzi. Izi zingayambitse mavuto osiyanasiyana monga kufooka kwa minofu, dzanzi, ndi paresthesia.

Mwachidule, CIDP ndi vuto la nthawi yayitali lomwe chipolopolo cha myelin chozungulira mitsempha ya m'mphepete chimawonongeka chifukwa cha kulephera kugwira ntchito bwino kwa chitetezo chamthupi chathu, zomwe zimapangitsa kuti mitsempha yambiri isagwire bwino ntchito. Kodi mukumvetsa?

Kodi kusiyana pakati pa Guillain-Barré Syndrome (GBS) ndi CIDP ndi kotani?

Mwina inuMwina munamvapo za `(Guillain-Barré Syndrome)` kapena ` (GBS) .` Matenda a CIDP ndi ofanana kwambiri ndi GBS. Madokotala amaona CIDP ngati mtundu wa GBS wa nthawi yayitali. GBS ndi matenda osowa omwe chitetezo chathu cha mthupi chimaukira mitsempha ya m'mphepete mwa thupi.

Koma kusiyana kwakukulu ndi nthawi. Choyipa kwambiri cha GBS nthawi zambiri chimabwera milungu iwiri kapena itatu zizindikiro zitayamba. Koma anthu ambiri amayamba kuchira pang'onopang'ono pambuyo pake. Koma CIDP imatenga nthawi yayitali. Zizindikiro zimakula pang'onopang'ono pakatha milungu isanu ndi itatu .

Kodi CIDP ndi yofala bwanji?

CIDP kwenikweni ndi vuto losowa kwambiri . Malinga ndi ofufuza, chiwerengero cha milandu yatsopano ya CIDP ku United States chili pakati pa 0.8 ndi 8.9 pa anthu 100,000 pachaka. Chiwerengerochi ndi chachikulu pang'ono, chifukwa CIDP imatha kukhudza anthu osiyanasiyana m'njira zosiyanasiyana, komanso chifukwa matendawa ndi ovuta kuwazindikira.

CIDP imatha kukulirakulira pa msinkhu uliwonse.

Kodi zizindikiro za CIDP ndi ziti?

Zizindikiro za CIDP zimatha kusiyana malinga ndi mtundu wake. Komabe, chizindikiro chofala kwambiri ndi kufooka kwa minofu komwe kumatenga milungu yosachepera isanu ndi itatu. Izi nthawi zambiri zimakhudza mbali zonse ziwiri za thupi mofanana. Makamaka:

• Minofu ya m'chiuno ndi m'ntchafu
• Minofu ya phewa ndi mkono wapamwamba
• Chikhatho ndi zala
• Mapazi ndi zala

Tangoganizirani, mwadzidzidzi zimakuvutani kudzuka pampando, kumva ngati simungathe kukwera masitepe, kapena kukuvutani kupesa tsitsi lanu kapena kugwira kapu. Zinthu ngati zimenezi zingachitike.

Zizindikiro zina zomwe zingawonekere ndi izi:

• Kufooka kwa minofu yokhudzidwa
• Kusamva bwino, kumva kuwawa, kapena kutaya kumva m'zala ndi zala zakumapazi (Paresthesia)
• Kuvuta kusunga bwino thupi komanso kusagwira bwino ntchito (monga kupunthwa)
• Kuvuta kuyenda kapena kutayika kwathunthu kwa kuyenda
• Kutayika kapena kufooka kwa deep tendon reflexes (izi ndi zomwe dokotala adzayesa pogogoda bondo ndi nyundo yaying'ono)
• Ululu wa Neuropathy. Uwu ndi ululu womwe umamveka ngati kutentha kapena kugwedezeka ndi magetsi.

Kawirikawiri, mukhoza kuona zizindikiro monga:

• Kuvuta kumeza (Dysphagia) ndi kufooka kwa khosi lapamwamba
• Masomphenya Awiri

Zizindikirozi zimatha kusintha pakapita nthawi. Zingayambe pang'onopang'ono, kapena zingapitirire mofulumira. Nthawi zina zimatha kubwera ndi kutha, kutha patatha masiku angapo, kenako n'kubwereranso. Ngati muli ndi zizindikirozi, ndikofunikira kupita kwa dokotala mwachangu.Kuzindikira msanga ndi kulandira chithandizo kumathandiza kwambiri kuti munthu achire.

Kodi pali mitundu yosiyanasiyana ya CIDP?

Inde, pali mitundu yosiyanasiyana ya CIDP, ndipo zizindikiro zake zimasiyana pang'ono.

Mtundu wofala kwambiri ndi CIDP wamba , womwe umayambitsa kufooka kwa minofu ndi zizindikiro za kumva (monga dzanzi) mbali zonse ziwiri za thupi.

Mitundu ina ya atypical ndi:

• ` (Multifocal Motor Neuropathy)`: Izi zimangokhudza kufooka kwa minofu. Kufooka kumeneku sikufanana, zomwe zikutanthauza kuti kungakhudze dera limodzi lokha mbali imodzi ya thupi, kapena madera angapo m'njira zosiyanasiyana.
• (Lewis-Sumner Syndrome): Izi zimaphatikizapo kufooka kwa minofu kosafanana komanso zizindikiro za kumva.
• ` (Pure Sensory CIDP)`: Izi zingayambitse dzanzi, kupweteka, mavuto okhazikika, komanso kuyenda molakwika. Koma palibe kufooka kwa minofu.
• `(Pure Motor CIDP):`: Mu izi, kufooka kwa minofu ndi kutayika kwa mphamvu zomwe zimakhudza mbali zonse ziwiri za thupi kungawonekere, koma palibe zizindikiro za kumva.

Ofufuza akuphunzirabe mitundu ina ya CIDP.

Kodi chimayambitsa CIDP ndi chiyani?

Monga tafotokozera kale, ofufuza amakhulupirira kuti CIDP imayamba chifukwa cha kulephera kwa chitetezo chamthupi chathu. Ngakhale kuti chifukwa chenicheni sichinadziwikebe, chitetezo chathu chamthupi chimawona sheath ya myelin ngati mdani kenako chimayamba kuiukira (yomwe imayambitsa autoimmune reaction).

Chigoba cha myelin ndi gawo loteteza maselo athu a mitsempha. Chimazungulira gawo lalitali la ulusi wa mitsempha (axon). Myelin ndi yomwe imalola kuti ma impulse amagetsi ayende bwino mu mitsempha. Myelin ikawonongeka, ma impulse awa amagetsi amayenda pang'onopang'ono, kapena amatayika kwathunthu. Kenako "mauthenga" safika komwe akuyenera kupita. Ndicho chomwe chimayambitsa zizindikiro za CIDP.

Tangoganizirani waya wamagetsi wotetezedwa bwino. Umayendetsa bwino magetsi. Koma chimachitika nchiyani ngati chidebe cha pulasitiki pa wayayo chatuluka m'malo ena? Mphamvuyo ikatuluka, kapena sikuyenda bwino, sichoncho? Ndicho chimene chimachitika chidebe cha myelin chikawonongeka.

Kodi CIDP imapezedwa bwanji?

Kuzindikira matenda a CIDP kungakhale kovuta chifukwa mitundu yosiyanasiyana imakhala ndi zizindikiro zosiyana. Kuti adziwe matenda a CIDP, dokotala wanu achita izi:

• Adzamvetsera mosamala zizindikiro zanu ndikufunsa za mbiri yanu ya matenda .
• Kuyezetsa thupi ndi kuyezetsa ubongo kumachitika.
• Mayeso angapo apadera angaperekedwe kuti atsimikizire matenda kapena kuthetsa matenda ena.

Ndi mayeso ati omwe amagwiritsidwa ntchito pozindikira CIDP?

Izi ndi mayeso omwe angathandize kutsimikizira CIDP ndikuchotsa zifukwa zina:

• ` (Electromyography - EMG)` ` (Nerve Conduction Tests)`: ‍ ‍ . CIDP ` (Demyelinating)` ( , ) . CIDP .

• Kuboola Msana/Lumbar: Mu mayesowa, dokotala amaika singano yaying'ono kumbuyo kwanu ndipo amatenga chitsanzo cha madzi a m'mitsempha yanu (CSF) . Chitsanzochi chimatumizidwa ku labu kuti akayesedwe. Mwa anthu 85% mpaka 90% omwe ali ndi CIDP, kuchuluka kwa maselo oyera m'magazi kumakhala koyenera, koma kuchuluka kwa mapuloteni kumakhala kokwera. Zolakwika zina mu CSF zitha kusonyeza vuto lina.

• ` (MRI - Magnetic Resonance Imaging)` : `(Nerve Roots)` MRI `(Contrast Dye)` , CIDP .

• Kuyezetsa Magazi: Dokotala wanu angakupatseni mayeso a magazi kuti athetse matenda ena omwe angayambitse matenda a mitsempha, monga matenda a shuga, kusowa kwa mavitamini, matenda a chithokomiro, matenda a Lyme, HIV/AIDS, ndi lymphoma. Angayang'anenso ma antibodies ena omwe apezeka kuti akugwirizana ndi CIDP.

• Kufufuza Mitsempha: Nthawi zambiri, dokotala angalimbikitse kufufuzidwa kwa mitsempha, komwe chidutswa cha mitsempha chimachotsedwa ndikuwunikidwa kuti awone ngati sheath ya myelin yawonongeka.

Kodi mankhwala a CIDP ndi otani?

Pali njira zitatu zazikulu (zoyambira) zothandizira CIDP:

• Corticosteroids: Mankhwala a steroid, monga prednisolone, amathandiza kuchepetsa kutupa. Kwa anthu ambiri, ma steroid awa okha angathandize kuchepetsa zizindikiro. Komabe, ma steroid amatha kukhala ndi zotsatirapo zoyipa kwambiri, kotero kugwiritsa ntchito mankhwalawa kwa nthawi yayitali kumakhala kochepa. Dokotala wanu angakupatseninso mankhwala ena (immunosuppressants) pamodzi ndi ma steroid.

• ` (Plasma Exchange / Plasmapheresis)`: ‍, ‍ , ‍ , . , , ‍ `(Antibodies)` . ‍ . , ‍ ‍ .

• Chithandizo cha Immunoglobulin Chogwiritsa Ntchito Mitsempha (IVIG): Mu chithandizochi, mapuloteni otchedwa immunoglobulin (mapuloteni omwe chitetezo chathu cha mthupi chimapanga mwachibadwa kuti chiukire owononga) amaperekedwa kudzera m'mitsempha (IV). Immunoglobulin iyi imapezeka kuchokera m'magazi a anthu ambiri athanzi. IVIG ingachepetse kuwonongeka komwe chitetezo chanu cha mthupi chimachita ku mitsempha yanu. IVIG ingapatsidwe mlingo waukulu kwambiri poyamba, ndipo mungafunike kulandira chithandizochi nthawi ndi nthawi kwa miyezi ingapo, kapena zaka zambiri.

Ofufuza pakali pano akuphunzira njira zina zochizira CIDP. Mungakhalenso ndi mwayi wochita nawo mayeso azachipatala a CIDP. Lankhulani ndi dokotala wanu za izi.

Kodi moyo uli bwanji ndi CIDP? (Zomwe zimachitika nthawi zambiri)

Chiyembekezo cha matendawa kwa nthawi yayitali chimadalira zinthu zingapo:

• Zaka zanu pamene CIDP inayamba.
• Momwe matendawa amakulira komanso mtundu wa matenda .
• Momwe matendawa adadziwikira mwachangu komanso momwe chithandizo chidayambira .
• Momwe thupi lanu limayankhira poyamba mukalandira chithandizo.

Pafupifupi 90% ya anthu omwe ali ndi CIDP amatha kuchiritsidwa ndi chithandizo. Koma pafupifupi 50% ya anthu amabwereranso ku matendawa. Kawirikawiri, nthawi yayitali anthu omwe amapezeka ndi CIDP ali aang'ono amakhala ndi chiyembekezo chabwino. Ngati simulandira chithandizo chilichonse cha CIDP, mitsempha yokhazikika imatha kuwonongeka, zomwe zingayambitse kulumala kwina.

Dokotala wanu adzatha kukupatsani lingaliro labwino la zomwe mungayembekezere mtsogolo kutengera vuto lanu.

Kodi CIDP imafupikitsa nthawi yoyembekezera moyo?

CIDP si matenda oopsa. Anthu omwe ali ndi matendawa nthawi zambiri amakhala ndi moyo wofanana ndi wa munthu amene alibe matendawa. Choncho palibe chodetsa nkhawa.

Kodi CIDP ingapewedwe?

Popeza ofufuza sanapeze chomwe chimayambitsa CIDP, pakadali pano palibe njira yodziwika yopewera matendawa.

Ndiyenera kupita liti kwa dokotala? / Ndiyenera kupita liti ku chipinda chadzidzidzi?

Ngati mwapezeka ndi CIDP, muyenera kupita kwa dokotala nthawi zonse kuti muwone zizindikiro zanu ndikulandira chithandizo. Zizindikiro za CIDP zimatha kubwera ndi kutha kwa miyezi kapena zaka, kotero chithandizo chopitilira chingakhale chofunikira.

Kawirikawiri, CIDP imatha kukhudza minofu yofunikira kuti munthu apume . Ngati mukuvutika kupuma , imbani 911 (kapena nambala yanu yadzidzidzi yapafupi) nthawi yomweyo, kapena pitani ku chipinda chadzidzidzi chapafupi. Ichi ndi chadzidzidzi.

Pomaliza, zinthu zoti muzikumbukira

Zingakhale zoopsa kumva ngati simungathe kulamulira thupi lanu. Koma nkhani yabwino ndi yakuti zizindikiro za CIDP (Chronic Inflammatory Demyelinating Polyneuropathy) zitha kuchiritsidwa, makamaka ngati muyamba chithandizo msanga. Kumbukirani kuti gulu lanu lachipatala lili nanu panjira iliyonse kuti muthane ndi vutoli. Choncho khalani olimba mtima ndipo tsatirani malangizo a dokotala wanu.

` CIDP, Neuropathy, Kufooka kwa Minofu, Kusanza, Chitetezo cha Mthupi, Myelin, Nervous System, Chithandizo cha CIDP, Chronic Inflammatory Demyelinating Polyneuropathy