Kodi mukukumbukira momwe mumamvera mukamathamangitsidwa mwadzidzidzi ndi galu mumsewu, kapena mukamalandira pepala lanu la mafunso m'manja mwanu? Mtima wanu umagunda, mtima wanu umagunda mofulumira, thupi lanu limazizira ndipo thukuta limatuluka... Umu ndi momwe timatchulira yankho la " nkhondo-kapena-kuthawa ". Ndiko kuti, njira ya thupi yokonzekera "nkhondo kapena kuthawa." Tonse tamva za adrenaline, yomwe ikugwira ntchito m'matupi athu panthawiyi. Koma kodi mwamvapo za m'bale wake, yemwe amagwira ntchito mofanana kwambiri ndi adrenaline, koma mwanjira yosiyana pang'ono? Amatchedwa norepinephrine. Tikambirana za izi ziwiri lero.
Kodi ma catecholamine awa ndi chiyani?
Mwachidule, Norepinephrine ndi Epinephrine ndi mamembala awiri a gulu la mahomoni otchedwa 'Catecholamines' . Ma mahomoni amenewa amapangidwa m'thupi lathu ndi tiziwalo tiwiri tating'onoting'ono tomwe tili pamwamba pa impso. Timatcha awa kuti 'Adrenal Glands'. Nthawi zina awa amapangidwanso ndi ubongo ngati 'Neurotransmitters' , amithenga a mankhwala omwe amanyamula mauthenga mu dongosolo la mitsempha.
Chiwalo china chofunikira kwambiri m'gululi ndi dopamine . Mukamva mantha, kuopsezedwa, kapena kupsinjika maganizo, mahomoni atatuwa amagwira ntchito limodzi kukonzekera thupi lanu. Pamene awa ali pamlingo wapamwamba m'thupi lanu,
- Kuchuluka kwa magazi omwe amapita ku ubongo ndi minofu kumawonjezeka.
- Kusamala ndi kusamala kumawonjezeka.
- Kugunda kwa mtima kumawonjezeka.
- Kuthamanga kwa magazi kumawonjezeka.
Nthawi zina, ngati muli ndi zizindikiro zosatha monga kuthamanga kwa magazi komwe sikulamuliridwa ndi chithandizo, nkhawa pafupipafupi, nseru, komanso mutu waukulu, dokotala wanu angakuwuzeni kuti muyesedwe magazi ndi mkodzo kuti muwone kuchuluka kwa ma catecholamines awa. Kuchuluka kwa izi nthawi zonse kungakhale chizindikiro cha khansa yamtundu wosowa yomwe imayamba m'matenda a adrenal.
Norepinephrine ndi Epinephrine - Ntchito Ziwiri kwa Awiri
Ngakhale kuti awiriwa amagwira ntchito limodzi, ntchito zawo zazikulu zimasiyana pang'ono. Tiyeni tiwone momwe zimagwirira ntchito.
| Norepinephrine (Noradrenaline) | Epinephrine (Adrenaline) |
|---|---|
| Kawirikawiri neurotransmitterImagwira ntchito ngati mthenga mu dongosolo la mitsempha. | Nthawi zambiri imagwira ntchito ngati mahomoni . Pakagwa mwadzidzidzi, imatulutsidwa m'magazi kuchokera ku adrenal gland. |
| Imagwira ntchito nthawi zonse m'thupi, kulamulira zinthu monga kugona, kusamala, ndi kuthamanga kwa magazi. | Makamaka imachitika nthawi yadzidzidzi yokha . |
| Ntchito yaikulu ndi kusunga kuthamanga kwa magazi mwa kutsekereza mitsempha yamagazi. | Ntchito yaikulu ndikufulumizitsa kugunda kwa mtima, kuwonjezera mphamvu, komanso kuchepetsa kumva ululu. |
Kodi chimachitika ndi chiyani ndi norepinephrine?
Norepinephrine ili ngati chowongolera chomwe chimakhala m'thupi lathu nthawi zonse. Sichimagwira ntchito pazochitika zadzidzidzi zokha, komanso pa moyo watsiku ndi tsiku.
- Kusamala ndi kugona: Norepinephrine imakuthandizani kudzuka m'mawa ndipo imakuthandizani kukhala maso komanso kukhala maso tsiku lonse. Ngakhale mutadzuka mwadzidzidzi, norepinephrine imatulutsidwa kuti ikuthandizeni kukhala wochita masewera olimbitsa thupi.
- Kuthamanga kwa magazi: Kumapangitsa kuti mitsempha ya magazi ichepetse kuti kuthamanga kwa magazi kusatsike kwambiri. Komabe, ngati kuchuluka kumeneku kuli kokwera nthawi zonse, kungayambitse kuthamanga kwa magazi.
- Maganizo: Kuchepa kwa magazi kumayambitsa kuvutika maganizo ndi mavuto ena amisala. Komanso, kuchuluka kwa norepinephrine mwadzidzidzi kungayambitse chisangalalo ndi mantha .
Kodi chimachitika ndi chiyani ndi Epinephrine (Adrenaline)?
Epinephrine ndiye adrenaline yomwe tonse timaidziwa. Ndi yomwe imabwera kudzathandiza ngati ngwazi pakagwa ngozi.
- Mphamvu ndi liwiro: Zimawonjezera kugunda kwa mtima ndi kuthamanga kwa magazi, ndipo zimawonjezera shuga (shuga) m'magazi, zomwe zimakupatsirani mphamvu nthawi yomweyo.
- Kuchepetsa ululu : Ngakhale mutavulala, kungathe kuchepetsa ululu kwakanthawi, kukuthandizani kupitiriza kumenyana kapena kuthamanga.
- Kuonjezera mphamvu: Epinephrine ingathandizenso mphamvu zanu kwakanthawi.
Komabe, ngati kuchuluka kwa epinephrine mwa munthu amene nthawi zonse amakhala ndi nkhawa kumakhala kokwera nthawi zonse, kungayambitse kusakhazikika, kusowa tulo, komanso kuwononga mtima.
Kodi izi zimagwiritsidwa ntchito bwanji ngati chithandizo chamankhwala?
Chifukwa cha mphamvu komanso zotsatira zake mwachangu, madokotala amagwiritsanso ntchito ngati mankhwala.
| Nthawi yoti mupereke Norepinephrine | Nthawi yoti mupereke epinephrine |
|---|---|
| Kuonjezera kuthamanga kwa magazi pamene kwatsika kufika pamlingo woika moyo pachiswe (monga septic shock, cardiac arrest). | Kubwezeretsa mphamvu (CPR) pamene mtima waima. |
| Pamene kupanikizika kumachepa chifukwa cha mankhwala oletsa ululu msana. | Monga chithandizo chadzidzidzi cha zovuta zazikulu za ziwengo (anaphylaxis) . |
| Mankhwala ena a ADHD ndi oletsa kuvutika maganizo amagwira ntchito powonjezera kuchuluka kwa Norepinephrine muubongo. | Kutsegula njira zopumira mpweya mu mphumu . |
| Ngati munthu wagwidwa ndi mantha chifukwa cha kuvulala kwa msana. | Kuti diso likhale lolimba nthawi ya opaleshoni ya maso. |
Epinephrine ndi zotsatira zoopsa za ziwengo (Anaphylaxis)
Chimodzi mwa zinthu zofunika kwambiri zomwe zimagwiritsidwa ntchito ndi epinephrine ndi chithandizo chadzidzidzi cha matenda oopsa (anaphylaxis), omwe amatha kupha anthu. Anthu ena amatha kukhala ndi vutoli atakhala ndi zakudya zina kapena kulumidwa ndi tizilombo (monga kulumidwa ndi mavu).
Zizindikiro zina za anaphylaxis ndi izi:
- Kutupa kapena kuuma kwa pakhosi
- Kuvuta kupuma
- Kulimba pachifuwa kapena chifuwa
- Chizungulire kapena kutaya chidziwitso
Anthu omwe ali ndi ziwengo zoopsa amalangizidwa kuti nthawi zonse azinyamula epinephrine auto-injector yolembedwa ndi dokotala (monga EpiPen). Kuzibaya mwachangu kungapulumutse moyo ngati pali ziwengo.
Chofunika Kwambiri: Ngati, ngakhale mutagwiritsa ntchito jakisoni wa epinephrine, zizindikiro zanu sizikutha kwathunthu kapena ngati zizindikirozo zikubwereranso, ndikofunikira kupita ku Dipatimenti Yodzidzimutsa ya Chipatala (ETU) nthawi yomweyo.
Kodi chimachitika n’chiyani ngati mahomoni amenewa achepa m’thupi?
Nthawi zina, kupanga mahomoni amenewa m'thupi lathu kumatha kuchepa. Kuchepa kwa mahomoni amenewa kumatha kugwirizanitsidwa ndi mavuto osiyanasiyana azaumoyo.
- Mavuto okhudzana ndi kuchepa kwa norepinephrine: Nkhawa, kukhumudwa, ADHD, mutu, kuiwala, mavuto ogona, kuthamanga kwa magazi.
- Mavuto okhudzana ndi kuchepa kwa epinephrine m'magazi: nkhawa, kuvutika maganizo, mutu, mavuto ogona, kuchepa kwa shuga m'magazi (hypoglycemia).
Ngati muli ndi zizindikiro ngati izi, ndi bwino kulankhula ndi dokotala wanu kuti mudziwe ngati chifukwa chake ndi kusintha kwa kuchuluka kwa mahomoni.
Uthenga Wopita Nawo Kunyumba
- Norepinephrine ndi epinephrine ndi mahomoni awiri a "nkhondo kapena kuthawa" omwe amakuthandizani mukamaopa kapena kuopsezedwa.
- Norepinephrine (Noradrenaline) ili ngati thermostat ya thupi. Imagwira ntchito nthawi zonse, kulamulira zinthu monga chidwi ndi kuthamanga kwa magazi.
- Epinephrine (Adrenaline) ili ngati alamu ya moto. Imangolira pakagwa ngozi ndipo imakupatsani mphamvu nthawi yomweyo.
- Monga mankhwala, Norepinephrine imagwiritsidwa ntchito makamaka kukweza kuthamanga kwa magazi kotsika kwambiri, ndipo Epinephrine imagwiritsidwa ntchito ngati chithandizo chachangu cha zovuta zazikulu za ziwengo (anaphylaxis).
- Kusalingana kwa mahomoni amenewa kungakhudze thanzi lanu la thupi ndi la maganizo, choncho funsani upangiri wa dokotala ngati muli ndi nkhawa.
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