Kodi mumavutika ndi mayendedwe osalamulirika a thupi? (Tardive Dyskinesia & Chorea) - Tiyeni tikambirane za Ingrezza!

Kugwedezeka kwa miyendo yanu kapena kusintha mawonekedwe a nkhope yanu popanda kulamulira kwanu kungakhale kovuta kwambiri. Zingapangitse kuti zikhale zovuta kuchita ntchito za tsiku ndi tsiku kapena kucheza ndi anthu anayi. Anthu ambiri amavutika maganizo chifukwa cha matenda otere. Ngati inu kapena munthu wina wapafupi nanu mwakumanapo ndi izi, nkhaniyi idzakhala yofunika kwambiri kwa inu.

Kodi Tardive Dyskinesia ndi Chorea ndi chiyani?

Mwachidule, awa ndi matenda awiri omwe amachitika chifukwa cha mayendedwe a matupi athu.

Tardive Dyskinesia (TD): Uwu ndi mkhalidwe womwe timakumana ndi kusuntha thupi mosadzifunira, makamaka nkhope ndi miyendo. Izi zitha kuphatikizapo lilime lotuluka popanda kudzifunira, kumenya milomo, kuphethira maso, kapena kugwedeza miyendo. Vutoli likhoza kuchitika chifukwa chogwiritsa ntchito mankhwala ena oletsa matenda amisala kapena mankhwala ena am'mimba kwa nthawi yayitali.

Chorea: Ichi ndi vuto la kuyenda lomwe limayamba chifukwa cha matenda a majini otchedwa Huntington 's Disease . Mu matenda a Huntington, maselo amitsempha muubongo amawonongeka pang'onopang'ono. Izi zimayambitsa mavuto pakuganiza, kulamulira malingaliro, komanso kuyenda kwa thupi. Chorea imayambitsa kuyenda kosalamulirika kwa manja, mapazi, ndi nkhope.

Mankhwala a Ingrezza amathandiza kulamulira mayendedwe osalamulirika omwe amachitika m'mikhalidwe yonse iwiri. Koma kumbukirani, Ingrezza sachiza zizindikiro zina za matenda a Huntington (monga mavuto oganiza).

Kodi mankhwala a Ingrezza amagwira ntchito bwanji?

Kuti timvetse izi, choyamba tiyenera kudziwa za kamtumiki kakang'ono ka mankhwala muubongo mwathu. Dzina lake ndi Dopamine . Kunena zoona, Dopamine ndi neurotransmitter. Dopamine iyi ndi yofunika kwambiri polamulira mayendedwe a thupi lathu.

Tangoganizirani zomwe zimachitika ngati ubongo wathu utumiza dopamine yochuluka kwambiri? Monga momwe madzi amayatsira mofulumira kwambiri, amakhulupirira kuti zizindikiro za dopamine zikawonjezeka, matupi athu amakhala osachitapo kanthu .

Izi ndi zomwe Ingrezza amachita. Imayang'ana puloteni muubongo wathu yotchedwa VMAT2 (vesicular monoamine transporter 2) . Puloteni iyi ndi yomwe imathandiza kutulutsa dopamine. Mwa kulamulira ntchito ya VMAT2, Ingrezza amachepetsa dopamine yochuluka. Zili ngati kuyatsa pompo pang'ono. Zotsatira zake, mayendedwe osalamulirika amachepa pang'onopang'ono.

Kodi ndiyenera kugwiritsa ntchito bwanji mankhwalawa?

Ingrezza ndi mankhwala omwe amabwera ngati kapisozi. Akhoza kumwedwa ndi chakudya kapena ayi. Dokotala wanu adzakulemberani mankhwalawa. Musamwe mopitirira muyeso kapena mochepera kuposa mlingo womwe dokotala wanu wakuuzani kuti mumwe.

Mlingo wamba walembedwa mu tebulo ili m'munsimu, koma dokotala wanu angasinthe izi kutengera matenda anu.

Momwe mungatengere kapisozi ya Ingrezza Sprinkle

Anthu ena amavutika kumeza makapisozi. Kwa anthu amenewa, pali mtundu wapadera wotchedwa "Ingrezza Sprinkle." Umu ndi momwe mungagwiritsire ntchito:

1. Tsegulani mosamala kapisoziyo ndikuyika tinthu tating'onoting'ono ta mankhwala (zowazira) mkati mwake mu supuni ya tiyi ya chakudya chofewa monga applesauce, yogurt, kapena pudding.

2. Musamatafune kapena kuphwanya mankhwalawa .

3. Idyani supuni yonse ya chakudya chosakaniza ndi mankhwala nthawi yomweyo .

4. Kenako imwani kapu ya madzi (pafupifupi 240 ml).

5. Musasakanize mankhwalawa ndi mkaka kapena madzi.

Kodi mumadziwa bwanji ngati mankhwalawo akugwira ntchito?

Malinga ndi kafukufuku wazachipatala, zizindikiro zimatha kusintha pakatha milungu iwiri kuchokera pamene mwayamba kugwiritsa ntchito Ingrezza. Mudzaona kuti mayendedwe osalamulirika a thupi akuchepa pang'onopang'ono.

Dokotala wanu adzayamba kumwa mankhwala ochepa ndikusintha mlingo malinga ndi momwe mukufunira kuti aone momwe thupi lanu limayankhira. Chifukwa chake zingatenge nthawi kuti muwone zotsatira zabwino. Ngati mukuona kuti zizindikiro zanu sizikuyenda bwino kapena zikuipiraipira, uzani dokotala nthawi yomweyo. Akhoza kusintha mlingo, kuwonjezera mankhwala ena, kapena kukusinthani ndi mankhwala ena ngati pakufunika kutero.

Zotsatirapo zomwe zingakhalepo komanso momwe mungathanirane nazo?

Monga mankhwala ena aliwonse, Ingrezza ingayambitse zotsatira zina zoyipa, ngakhale kuti si aliyense amene amazilandira.

• Zotsatira zoyipa kwambiri pakati pa odwala omwe ali ndi tardive dyskinesia (TD) ndi izi:
• Kugona tulo

• Zotsatira zoyipa zomwe zimachitika pakati pa odwala a Chorea:
• Kugona tulo
• Ziphuphu pakhungu (Hives)
• Kutupa pakhungu
• Kuvutika kugona

Kodi mumachita bwanji ndi izi?

• Kugona: Pewani zinthu zomwe zimafuna kukhala maso, monga kuyendetsa galimoto kapena kugwiritsa ntchito makina, mpaka mutadziwa bwino momwe mankhwalawa amakukhudzirani.
• Ziphuphu pakhungu kapena mabala: Izi zitha kukhala zizindikiro za vuto la ziwengo. Ngati izi zitachitika, imbani dokotala wanu nthawi yomweyo, kapena pitani ku chipinda chapafupi chadzidzidzi cha chipatala (ETU).
• Kusagona: Pali zinthu zomwe mungachite nokha. Kuchepetsa kumwa zakumwa zokhala ndi caffeine monga khofi, tiyi, ndi cola, kukhala ndi chizolowezi chogona ndi kudzuka nthawi yomweyo tsiku lililonse, kusunga chipinda chanu chogona chili chamdima, komanso kuchepetsa kugwiritsa ntchito mafoni ndi mapiritsi musanagone kungathandize.

Kuyanjana kwa Mankhwala

Ngati mukumwa Ingrezza, ndikofunikira kwambiri kuuza dokotala wanu za mankhwala ena onse omwe mukumwa, ngakhale mavitamini, chifukwa mankhwala ena amatha kusokonezana ndi Ingrezza.

• Mankhwala oletsa monoamine oxidase (MAOIs):Mankhwala awa amagwiritsidwa ntchito pochiza matenda a kuvutika maganizo kapena matenda a Parkinson. Mankhwala a MAOI awa ndi oletsedwa kwambiri kumwedwa ndi Ingrezza.
• Digoxin: Iyi ndi mankhwala omwe amagwiritsidwa ntchito pochiza kulephera kwa mtima komanso kugunda kwa mtima kosakhazikika. Kumwa Ingrezza ndi Digoxin kungapangitse kuti Digoxin ikhale yambiri m'magazi mwanu, zomwe zimayambitsa zotsatirapo zoyipa. Dokotala wanu adzayesa magazi anu ndikuchepetsa mlingo wanu wa Digoxin ngati pakufunika kutero.
• Mankhwala oletsa/oyambitsa CYP3A4 ndi CYP2D6: Awa ndi mawu ovuta kwambiri azachipatala. Amagwiritsidwa ntchito pa mitundu yosiyanasiyana ya mankhwala. Chinthu chosavuta komanso chotetezeka chomwe mungachite ndikuuza dokotala wanu za mankhwala onse omwe mukumwa. Iye adzasintha chilichonse chofunikira.