Kodi inunso mukuvutika ndi mayendedwe osalamulirika a thupi? Tiyeni tiphunzire za mankhwala a Austedo

Kodi ndi zopanda phindu bwanji kumva ngati simungathe kulamulira thupi lanu? Tangoganizirani, pamene mukulankhula, kudya, kapena kuyesa kusaina chikalata, nkhope yanu, miyendo, kapena ziwalo zina za thupi lanu zimayamba kugwedezeka ndi kugwedezeka mosalamulirika... Izi ndi zosokoneza zazikulu pa moyo wanu watsiku ndi tsiku ndipo zingakupangitseni mantha kukumana ndi anthu. M'nkhaniyi, tikambirana za mankhwala omwe angathandize iwo omwe akuvutika ndi mayendedwe osalamulirika otere.

Matenda awiri akuluakulu omwe amachititsa kuti mayendedwe osalamulirika awa akhale otere ndi awa:

Mankhwala a Austedo amagwiritsidwa ntchito makamaka pochiza matenda awiri. Tiyeni tiwone zomwe zili.

1. Chorea chifukwa cha matenda a Huntington: Ngakhale kuti dzinali lingamveke ngati lovuta, mwachidule, ndi vuto lobadwa nalo. Pankhaniyi, maselo amitsempha muubongo amawonongeka pang'onopang'ono. Izi zimayambitsa mavuto pakuganiza, kulamulira malingaliro, ndi mayendedwe a thupi. Timatcha izi kuti mayendedwe osalamulirika, adzidzidzi, ogwedezeka, komanso ogwedezeka chorea .

2. Tardive Dyskinesia (TD): Iyi ndi matenda omwe amachititsanso kuti munthu asamayende mobwerezabwereza (monga kugwedezeka, kugwedezeka) nkhope (maso, pakamwa), manja, mapazi, ndi ziwalo zina za thupi. Chifukwa chachikulu cha izi ndi zotsatira zoyipa za mankhwala omwe amagwiritsidwa ntchito pa matenda ena, makamaka mankhwala oletsa matenda amisala.

Kodi Austedo imagwira ntchito bwanji m'thupi?

Ubongo wathu uli ngati malo akuluakulu otumizira mauthenga. Umatumiza mauthenga ku minofu m'thupi, monga "kusuntha" ndi "kuima," kudzera m'maselo a mitsempha. Atumiki a mankhwala omwe amanyamula mauthengawa amatchedwa ma neurotransmitters .

Dopamine ndi mthenga wofunikira kwambiri. Mu matenda onse awiri a Chorea ndi Tardive Dyskinesia (TD) omwe atchulidwa pamwambapa, amithenga ofanana ndi dopamine amenewa amatumiza mauthenga mopitirira muyeso kapena mosayenera. Izi zikutanthauza kuti minofu imalandira zizindikiro zambiri zosafunikira kuti "isunthe, isunthe." Ndicho chifukwa chake thupi limayamba kugwedezeka ndi kugwedezeka mosalamulirika.

Chomwe Austedo amachita ndikuwongolera kuchuluka kwa mauthenga osafunikira omwe akutumizidwa. Izi zikutanthauza kuti, zimathandiza kuchepetsa 'magalimoto' amenewo pang'ono ndikuchepetsa mayendedwe osafunikira.

Kodi mankhwalawa ayenera kugwiritsidwa ntchito bwanji?

Mapiritsi a Austedo amabwera m'mitundu iwiri.

• Piritsi lokhazikika: Dokotala wanu angakulangizeni kuti mutenge kamodzi kapena kawiri patsiku.
• Austedo XR: Iyi ndi piritsi ya 'Extended-Release' . Izi zikutanthauza kuti mankhwalawa amatuluka m'thupi kwa maola angapo. Chifukwa chake, nthawi zambiri amatengedwa kamodzi patsiku.

Dokotala wanu adzayamba kumwa mankhwala ochepa kwambiri (dose yoyambira) . Kenako, sabata ndi sabata, adzawonjezera mlingo pang'onopang'ono mpaka mutapeza mlingo wosamalira womwe umawongolera bwino zizindikiro zanu. Chifukwa chake, ndikofunikira kwambiri kusintha mlingo wanu monga momwe dokotala wanu akukulangizirani.

Kumbukirani zinthu izi mukamamwa mankhwala:

• Mapiritsi a Austedo wamba ayenera kumwedwa ndi chakudya. Mapiritsi a Austedo XR akhoza kumwedwa ndi chakudya kapena ayi.
• Musaswe, kuphwanya, kapena kutafuna piritsi. Mezani lonse ndi kapu ya madzi.
• Ngati mutenga Austedo XR, mungazindikire kuti piritsi lina, monga utoto wotsala, limatuluka mu ndowe yanu mankhwalawo atalowa kwathunthu. Izi ndi zachilendo ndipo siziyenera kukhala chifukwa chodera nkhawa.
• Ngati mwaphonya mlingo, imwani mwamsanga mukangokumbukira. Komabe, ngati nthawi yoti mutenge mlingo wotsatira yayandikira, thawani mlingo womwe mwaphonya ndikumwa mlingo wotsatira panthawi yokhazikika. Musamwe milingo iwiri nthawi imodzi kuti mubwezeretse womwe mwaphonya. Ngati simukudziwa, funsani dokotala wanu.

Kodi mumadziwa bwanji ngati mankhwalawo akugwira ntchito?

N'zovuta kuyembekezera zotsatira nthawi yomweyo. Zingatenge milungu ingapo mpaka miyezi kuti mayendedwe anu osalamulirika achepe. Ndikofunikira kukhala oleza mtima chifukwa dokotala wanu amatenga nthawi kuti apeze mlingo woyenera kwa inu.

Zotsatirapo zomwe zingatheke komanso momwe mungathanirane nazo?

Monga mankhwala ena aliwonse, Austedo ingayambitse mavuto mwa anthu ena. Komabe, si aliyense amene amawapeza. Gome ili m'munsimu likuwonetsa zina mwa zotsatirapo zomwe zimafala kwambiri komanso njira zosavuta zothanirana nazo.

Mankhwala ena omwe sagwirizana ndi mankhwalawa (Kuyanjana kwa Mankhwala)

Izi ndi zofunika kwambiri . Mukamamwa Austedo, pali mankhwala ena omwe sayenera kumwedwa limodzi nawo ndipo ayenera kumwedwa mosamala kwambiri.

Mankhwala omwe sayenera kumwedwa:

• MAOIs (Monoamine Oxidase Inhibitors): Awa ndi mtundu wa mankhwala operekedwa kwa kuvutika maganizo kapena matenda a Parkinson.
• Reserpine: Mankhwala akale omwe amagwiritsidwa ntchito pochiza kuthamanga kwa magazi.
• Tetrabenazine ndi Valbenazine: Awa ndi mankhwala ena omwe amagwiritsidwa ntchito pochiza matenda oyenda, monga Austedo. Kuwamwa pamodzi kungapangitse kuti pakhale zotsatirapo zoyipa kwambiri.

Mankhwala oti amwedwe mosamala:

• Zoletsa za CYP2D6: Izi ndi zovuta pang'ono. Mwachidule, kumwa Austedo pamodzi ndi mankhwala oletsa kuvutika maganizo monga bupropion ndi fluoxetine, kapena mankhwala a mtima monga quinidine kungawonjezere kuchuluka kwa Austedo m'magazi mwanu ndikuwonjezera chiopsezo cha zotsatirapo zake. Ngati mukumwa imodzi mwa mankhwalawa, dokotala wanu angachepetse mlingo wanu wa Austedo.
• Mankhwala oletsa matenda amisala (mankhwala a matenda amisala): Akamwedwa ndi Austedo, izi zitha kuwonjezera chiopsezo cha matenda monga parkinsonism, kuuma kwa minofu (neuroleptic malignant syndrome), komanso kusakhazikika (akathisia).
• Mankhwala ena omwe amayambitsa kugona ndi mowa: Austedo ingayambitse kugona. Chifukwa chake, kumwa pamodzi ndi mankhwala a ziwengo monga Benadryl kapena mankhwala ena omwe amayambitsa kugona kungapangitse kugona kwambiri. Pewani kumwa mowa kwathunthu mukamamwa Austedo.