Enspryng na NMOSD: Menya kuri iyi ndwara idasanzwe (Neuromyelitis Optica Spectrum Disorder)

Ese wabonye impinduka mu buryo butunguranye mu kureba kwawe, ububabare bw'amaso, cyangwa ububabare cyangwa intege nke mu maguru yawe? Bishobora kuba ikindi kintu. Uyu munsi turimo kuvuga ku ndwara idakunze kugaragara cyane mu gihugu cyacu, ariko ni ngombwa cyane kubimenya. Iyo ni Neuromyelitis Optica Spectrum Disorder , cyangwa NMOSD mu magambo ahinnye. Iyi ni indwara itera ubudahangarwa bw'umubiri ifata cyane cyane amaso yawe n'umugongo.

NMOSD ni iki? Enspryng ikora ite?

Mu magambo make, NMOSD ni igihe ubudahangarwa bw'umubiri wawe, ari bwo buryo buturinda indwara, butangira kwibasira uturemangingo twawe twiza. By'umwihariko, umubiri wawe utangira gukora ubudahangarwa bw'umubiri burwanya poroteyine runaka mu mitsi yawe yitwa `aquaporin-4 (AQP4).'

Iki gitero gitera ahanini kubyimba, cyangwa kubyimba, hafi y'imitsi yawe y'amaso (imitsi ijyana ubutumwa hagati y'ijisho ryawe n'ubwonko bwawe) n'umugongo. Uko ibi bikomeza, bishobora gutuma utabona neza kandi bikagorana kugenda.

Nta muti wa NMOSD uraboneka kugeza ubu. Uburyo bwo kuvura bugamije ahanini kugabanya ububyimbirwe, kugenzura ibimenyetso , no gukumira kongera kurwara.

Aha niho Enspryng igaragara. Enspryng ni umuti mushya w’ibinyabuzima. Uyu muti ushobora gufasha gukumira NMOSD kugaruka, cyane cyane niba ufite anti-AQP4 antibodies twavuze mbere mu maraso yawe.

Enspryng ikora mu kuziba indi poroteyine mu mubiri wacu yitwa ``interleukin-6 (IL-6).`` Kubera ko iyi poroteyine yitwa IL-6 inagira uruhare mu kubyimba guterwa n’uturemangingo twa anti-APQ4. Rero iyo IL-6 ifunzwe, kubyimba kuragabanuka, ibimenyetso biragenzurwa, kandi indwara ishobora kugabanuka.

Uyu muti nkwiye kuwukoresha nte?

Enspryng ni urushinge rwo munsi y'umubiri . Ubusanzwe rutangwa mu nda yo hasi cyangwa hagati mu itako.

• Inshinge eshatu za mbere zigomba gutangwa buri byumweru bibiri.
• Nyuma y'ibyo, ugomba kuyikubita rimwe gusa mu kwezi.

Ni ingenzi cyane kwibuka iminsi nyayo ugomba guterwamo izi nshinge. Shyira ikimenyetso cy'urwibutso kuri kalendari cyangwa kuri telefoni yawe. Niba wasibye guterwa inshinge, ugomba kuvugana na muganga wawe icyo wakora nyuma yaho.

Ntugahangayike, muganga wawe azaguhugura ku buryo bwo kwitera uru rushinge, aho rubatera, n'uburyo bwo guhindura aho rwaba ruherereye buri gihe. Buri gihe karaba intoki zawe neza mbere yo gutera urushinge.

Ni gute nabika umuti?

Uyu muti ugomba kubikwa muri firigo . Ariko ntuwubike muri firigo. Nanone, ntuwunyeganyeze. Kura umuti iminota 30 mbere yo guterwa urushinge hanyuma uwureke ugere ku bushyuhe bw'icyumba. Ntuzigere ushyushya umuti muri microwave cyangwa n'amazi ashyushye.

Ni gute ubu buvuzi bwakozweho ubushakashatsi?

Hakozwe ubushakashatsi bubiri bukomeye kugira ngo harebwe umutekano n'imikorere ya Enspryng. Ubu bushakashatsi bugereranya Enspryng n'umuti utagira ikintu gikora. Icyo gihe ni bwo dushobora kumenya neza niba uyu muti ufite akamaro cyangwa ingaruka nyazo.

Abitabiriye ubu bushakashatsi bose bari bafite NMOSD, amateka yo gusubira inyuma, n'amanota ari hagati ya 0 na 6.5 ku gipimo cya Expanded Disability Status Scale (EDSS), igipimo gipima urwego rw'ubumuga bwabo. (Amanota ya EDSS ya 0 bivuze ko nta bumuga bafite, 6.5 bivuze ko hari aho batabasha kugenda.)

Ubushakashatsi bwakozwe bwarebaga cyane cyane igihe byatwaye kugira ngo iyi ndwara igaruke. Byongeye kandi, hibanzwe ku mpinduka muri `Visual Analog Scale (VAS)`, ipima ububabare, na `Functional Assessment of Chronic Illness Therapy (FACIT)`, ipima umunaniro.

Ni ibihe bisubizo by'ubushakashatsi?

Muri ubwo bushakashatsi bwombi, abarwayi bafataga Enspryng bagaragaje ko basubira inyuma bake cyane ugereranyije n'abafataga placebo. Ibi bivuze ko Enspryng ishobora kugabanya ibimenyetso byawe n'umubare w'abasubira inyuma.

Ariko, abarwayi badafite antibodies za AQP4 ntacyo bungukiye cyane kuri Enspryng ugereranije na placebo.

Ni gute wakwirinda ingaruka mbi zibayeho?

Ingaruka mbi zikunze kugaragara z'uyu muti ni indwara zo mu mazuru no mu muhogo, kuribwa umutwe, isesemi, uduheri ku ruhu, indwara ya gastritis, umunaniro, n'ububabare mu ngingo cyangwa mu maguru. Bibwire muganga wawe niba ufite kimwe muri ibi.

Indwara zandurira mu mubiri

Hari ibyago byinshi byo kwandura indwara zisanzwe cyangwa zikomeye mu gihe ufata Enspryng. Bibwire muganga wawe niba urimo kuvurwa indwara. Nanone, bwira muganga wawe ako kanya niba ufite kimwe muri ibi bimenyetso bikurikira:

• Ibicurane, kubabara umubiri, umuriro, kubabara mu muhogo, inkorora idashira
• Uruhu rutukura cyangwa rubyimba
• Kubabara mu nda, impiswi
• Gushya iyo uri kunyara cyangwa gukenera kunyara kenshi

Ibisebe

Bwira muganga wawe niba ugize uduheri ku ruhu mu gihe ufata umuti. Niba uduheri twakwirakwiriye umubiri wose mu buryo butunguranye, jya mu cyumba cy’ubutabazi bw’ibanze cy’ibitaro (ETU) ako kanya.

Izi si zo ngaruka mbi zishobora kubaho gusa. Niba ufite ibimenyetso bikubangamiye, ganira na muganga wawe ku byerekeye ibyo.

Ni ibihe bipimo bigomba gukorwa mbere yo gutangira kuvurwa no mu gihe cyo kuvurwa?

Mbere yuko utangira Enspryng, muganga wawe azakora ibizamini byinshi by'amaraso kugira ngo arebe imikorere y'umwijima wawe, hepatite B, igituntu, cyangwa izindi ndwara. Ibi bizamini bishobora gukenerwa kongera gukorwa mu gihe cyo kuvurwa. Bityo rero ni ngombwa cyane ko ibizamini byawe bikorwa ku gihe.

Ese hari ibibazo bishobora kubaho ku yindi miti?

Nta mibanire ikomeye yavuzwe hagati ya Enspryng n'ibiribwa cyangwa indi miti. Ariko, ni ngombwa kubwira muganga wawe imiti yose ufata (harimo n'imiti ivura izindi ndwara, vitamine, imiti y'ibimera, n'inyongeramusaruro). Ibi bishobora gufasha gukumira ingaruka mbi zose zitari ngombwa.