Spindle Cell Sarcoma ni iki? Reka tubiganireho mu buryo bworoshye!

Ese wigeze uhangayikishwa n'ikintu kidasanzwe, nko kubabara cyangwa kubyimba amagufwa yawe cyangwa ahantu horoshye nk'imitsi yawe? Hari igihe ibi bishobora kuba ibisanzwe. Ariko, gake cyane, ibi bimenyetso bishobora kuba ikimenyetso cy'ikintu gikomeye. Rero, uyu munsi tugiye kuvuga ku bwoko bwa kanseri idakunze kugaragara, ariko ni ngombwa kumenya. Iyo yitwa Spindle Cell Sarcoma.

Ese koko Spindle Cell Sarcoma ni iki?

Muri make, Spindle Cell Sarcoma ni ubwoko budasanzwe bwa kanseri butera mu magufwa no mu ngingo zoroshye z'umubiri wacu. Ese wari uzi ko 'sarcoma' yerekeza ku turemangingo tudasanzwe, cyangwa ibibyimba, bitera muri ayo magufwa no mu ngingo zihuzwa nayo?

Noneho, ikintu cyihariye kuri Spindle Cell Sarcoma ni uko iyo urebye utwo turemangingo tudasanzwe ukoresheje mikorosikopi, tugaragara nk'"spindle". Spindle ni ishusho isa n'iy'ubuji, impande zikaba ntoya naho hagati zikaba nini gato. Niyo mpamvu yahawe izina ryayo.

Kubera ibizamini bya laboratwari bigezweho, abaganga bashoboye kumenya ubwoko burenga 75 bwa sarcoma. Spindle cell sarcoma ni imwe muri izo nkomoko. Mu by'ukuri, ijambo 'spindle cell sarcoma' rikoreshwa mu gusobanura sarcoma zidashobora gushyirwa mu byiciro neza n'ibizamini bimwe na bimwe bya laboratwari, nk'ibizinga cyangwa imiterere y'uturemangingo. Rero, ni ijambo rinini gato.

Ni hehe izi kanseri zikunze kugaragara cyane?

Indwara ya Spindle Cell Sarcoma ikunze kugaragara mu magufwa maremare y'umubiri wacu. Urugero:

• Igufwa ryawe ry'ikibero (`femur`)
• Igufwa ry'uruti rw'umugongo (`tibia`)
• Igufwa ryo hejuru ry'ukuboko (humerus)

Ariko, si aho hantu gusa. Hari abantu bafite indwara ya spindle cell sarcomas mu kibuno, mu mutwe no mu ijosi, no mu bindi bice by'umubiri.

Ni ubuhe bwoko bw'ingenzi bwa Spindle Cell Sarcoma?

Noneho, reba, sarcomas zose zitangirira mu ngingo zoroshye. Ni ukuvuga mu bintu nk'ibinure, imitsi, imitsi, imitsi, n'ingingo zikikije amagufwa. Abaganga bashyira kandi mu byiciro sarcomas za spindle cell bakurikije ubwoko bw'ingirabuzimafatizo kanseri itangiramo.

Mu gusobanukirwa ubwoko bw'uturemangingo n'imiterere yatwo muri ubu buryo, abaganga bashobora gusuzuma uburyo kanseri ishobora gukwirakwira. Ibi kandi bibafasha kumenya uburyo bwiza bwo kuvura.

Nubwo 'spindle cell sarcoma' ari ijambo ryagutse, hari ubwoko bwinshi bw'ingenzi:

• Sarcoma ya Pleomorphic Idatandukanye:Nk’uko izina ribigaragaza, uturemangingo turi muri ubwo bwoko bwa kanseri ntabwo "dutandukanye". Ibi bivuze ko bitaramenyekana neza ubwoko bw’uturemangingo kanseri yatangiriyeho. Uturemangingo turwaye muri iyo kanseri ni "pleomorphic", bivuze ko tuza mu buryo butandukanye n’ingano zitandukanye. Mu yandi magambo, ikibyimba ni uruhurirane rw’uturemangingo dukomoka mu bwoko butandukanye.
• Fibrosarcoma: Izi zikomoka ku turemangingo twitwa fibroblasts. Fibroblasts ni ingenzi mu kubaka ingirabuzimafatizo mu mibiri yacu.
• Leiomyosarcoma: Izi zitangirira mu turemangingo tw’imitsi tworoshye. Izi zitandukanye n’uturemangingo two mu mitsi y’amagufwa, dukoresha mu kwimura imibiri yacu no kubona imbaraga. Uturemangingo tw’imitsi tworoshye tuboneka mu ngingo zacu z’imbere, mu myobo y’umubiri, no mu magufwa amwe n’amwe nk’uturemangingo tworoshye.

Iyi ndwara ikunze kugaragara gute?

Kimwe n'ubundi bwoko bwa sarcoma, sarcoma ya spindle cell ni gake cyane . Mu by'ukuri, ifata munsi ya 10% bya kanseri zose zo mu magufwa n'imitsi yoroshye. Ibuka ko ari gake cyane ku buryo muganga wawe ashobora kudakeka ko ari kanseri mu ntangiriro. Ushobora kujya kwa muganga kenshi, ukabonana n'inzobere nyinshi, kandi ugakora ibizamini byinshi mbere yuko uhabwa isuzuma.

Sarcoma ya Spindle cell irashobora kugaragara ku muntu uwo ari we wese. Ariko, ikunze kugaragara ku bantu barengeje imyaka 40. Abantu barwara sarcoma yavuzwe haruguru akenshi baba bafite hagati y'imyaka 60 na 70.

Ni ibihe bimenyetso by'ibi?

Ibimenyetso bya spindle cell sarcoma biratandukanye. Biterwa n'ingano ya kanseri, umubare wa kanseri, n'amagufwa (cyangwa ibindi bice by'umubiri) uturemangingo twa kanseri turimo. Dore bimwe mu bimenyetso ugomba kwitondera cyane cyane :

• Ububabare bw'amagufwa: Ubu bubabare bushobora kubaho buri gihe cyangwa bukaza bugashira. Bushobora kumva nk'aho hari umuntu ugutera icyuma imbere.
• Gucika kw'igufwa igihe ryacitse intege kubera kanseri: Ibi byitwa 'kuvunika kw'indwara'. Igufwa rishobora kuvunika nubwo ryagwa gato.
• Ububabare cyangwa kubyimba iyo ukandagiye ahantu ikibyimba kiri: Hashobora no kuba hari ikibyimba kinini bihagije ku buryo gishobora gufatwa mu ntoki.
• Kudashobora kwimura ingingo yegereye ikibyimba neza: Tekereza niba ivi ryegereye, byaba bigoye kurinamira cyangwa kurigura.
• Umunaniro: Uyu si umunaniro usanzwe gusa. Ni umunaniro ukabije udashira uko waba usinziriye cyangwa uruhuka kose.
• Malaise: Kumva utameze neza , nta mpamvu igaragara, nk'aho nta mbaraga cyangwa inyungu ufite mu kintu icyo ari cyo cyose.

Ni iki gitera sarcoma y'uturemangingo tw'impinja?

Kimwe n'izindi kanseri zose, sarcoma ya spindle cell itangira iyo uturemangingo tuzima tubaye ibicurane. Utwo turemangingo twica dutera indwara tudashobora kwitabwaho, tugakora ibicurane. Utwo turemangingo dushobora kwangiza uturemangingo tuzima tuyikikije. Ikintu kibi cyane ni uko utwo turemangingo twa kanseri dushobora gutandukana n'uturemangingo twa mbere tugakwirakwira mu mubiri wose, tukangiza izindi ngingo n'utundi duce. Ibi ni byo twita metastasis, cyangwa kanseri ya metastasis.

Ariko, hari icyo ugomba kumenya. Ubusanzwe, uturemangingo tw’inyuma (iyo dukuze neza) mu by’ukuri ni ikintu cyiza. Uturemangingo tw’inyuma twirema aho ingingo zangiritse. Rero, kugira uturemangingo tw’inyuma ni ikimenyetso cy’uko igikomere cyawe kirimo gukira. Utwo turemangingo turashira iyo igikomere gikize.

Ariko, muri spindle cell sarcoma, izi spindle cells zikomeza gukura no kugwira. Abahanga mu bya siyansi ntibarabona impamvu imwe yihariye ituma izi cells ziba mbi cyane.

Ariko, abashakashatsi bavumbuye ko impinduka zimwe na zimwe mu ngirabuzimafatizo zishobora kongera ibyago byo kurwara iyi kanseri. 'Mutation' ni ikosa mu ngirabuzimafatizo zacu, sisitemu ibwira uturemangingo twacu uko dukora. Ku bijyanye na spindle cell sarcoma, izi mpinduka akenshi ziba mu muryango, bivuze ko zishobora kubaho mu miryango.

Ni ibihe bintu bishobora kongera ibyago byo kurwara iyi kanseri?

Hari ibintu byinshi bishobora kongera ibyago byo kurwara spindle cell sarcoma. Reka turebe ibyo ari byo:

• Gutera kw'amagufwa: Iki ni cyo gihe igufwa ripfa kuko ritabona amaraso ahagije. Nkuko mubizi, igufwa rikenera amaraso kugira ngo ribeho, ari na byo ogisijeni ikora.
• Indwara ya Fibrous Dysplasia: Muri iki kibazo, igufwa rizima risimburwa n'igufwa rifite fibrous. Ibi byongera ibyago byo kuvunika kandi (gake cyane) bishobora gutera indwara ya fibrosarcoma.
• Osteomyelitis: Iyi ni indwara ifata ingirabuzimafatizo ziri mu magufwa amwe, yitwa umwongo w'amagufwa. Ibi bishobora kubaho iyo bagiteri cyangwa izindi mikorobe ziva mu maraso yawe zijya mu magufwa zikanduza uturemangingo two muri yo.
• Indwara ya Paget y'amagufwa: Iyi ni indwara y'igihe kirekire (idakira). Itera amagufwa gucika intege no kuvunika byoroshye. Ibi bishobora kongera ibyago byo kurwara kanseri y'amagufwa, harimo na spindle cell sarcoma.
• Kuba narigeze guhabwa ubuvuzi bwa radiation kuri kanseri:Ubuvuzi bushingiye ku mirasire bukoresha imirasire ifite ingufu nyinshi (akenshi imirasire ya X ifite ingufu nyinshi) kugira ngo busenye uturemangingo twa kanseri. Ni gake cyane, imirasire ya spindle cell sarcomas ivuka mu duce twavuwe n'imirasire. Iyo ibi bibaye, iyi mirasire ikunze kugaragara nyuma y'imyaka myinshi ivuwe (imyaka irindwi kugeza kuri makumyabiri). Ariko ibuka ko munsi ya 1% by'abantu bahabwa ubu buvuzi bushingiye ku mirasire barwara iyi kanseri iterwa n'imirasire.

Ni izihe ngorane ziterwa na spindle cell sarcoma?

Iyi kanseri ituma amagufwa yawe ashobora kuvunika cyane aho ikibyimba cyabereye. Iyo igufwa ryavunitse, uturemangingo twa kanseri tuva muri iki kibyimba dushobora kujya mu turere turi hafi aho.

Ariko, haracyari impaka ku bijyanye no kumenya niba ubu bwoko bw'igufwa ryavunitse bugira icyo buhindura ku ihinduka rusange (ni ukuvuga ingaruka zishobora kubaho) za kanseri, cyangwa niba ingaruka zayo zifitanye isano gusa n'ikwirakwira rya kanseri kure (ikwirakwira rya metastasis).

Ni gute indwara ya spindle cell sarcoma ipimwa?

Mbere yuko umuganga wawe asuzuma kanseri yawe no kuyipima, ushobora kuba ufite uburyo butandukanye bwo kuyipima. Gupima kanseri bituma abaganga bashyira mu byiciro ubukana bwa kanseri bakurikije ingano yayo, aho iherereye, ndetse niba yarakwirakwiriye. Iyo bapima kanseri y'amagufwa, bareba niba ikibyimba ari 'icy'icyiciro cyo hejuru' cyangwa 'icy'icyiciro cyo hasi'. Ibibyimba byo mu rwego rwo hejuru bigira uturemangingo tudasanzwe . Bishobora gukura no gukwirakwira vuba.

Inyinshi mu ndwara za spindle cell sarcomas ziba zifite imiterere yo hejuru.

Ibizamini byo gushushanya

Nubwo ibizamini byo gufata amashusho bitabasha kugaragaza ubwoko bwa kanseri, bishobora kwerekana ingano n'aho ikibyimba giherereye. Bishobora kandi kwerekana niba kanseri yarakwirakwiriye kurenza ikibyimba cy'ibanze.

• X-rays: X-rays zishobora kugaragaza ibibyimba cyangwa ibindi bintu bitameze neza mu magufwa yawe. X-ray yo mu gituza ishobora kureba niba kanseri yarageze mu bihaha. Metastatic spindle cell sarcoma ikunze gukwirakwira mu bihaha mbere.
• MRI Scan: MRI ikoresha rukuruzi nini, imiraba ya radiyo, na mudasobwa kugira ngo ifate amafoto y'ibintu biri mu mubiri. Bitandukanye na X-rays, MRI ishobora kwerekana ingingo zoroshye mu buryo burambuye. Ibi ni ingirakamaro cyane ku baganga kugira ngo bamenye utubyimba tw'ingingo zoroshye bakeka ko ari sarcomas.
• CT Scans: CT scans ikoresha X-rays na mudasobwa kugira ngo ikore amashusho y’amagufwa n’uturemangingo tworoshye mu buryo bwa 3D. Ku bijyanye na spindle cell sarcoma, CT scans ishobora kwerekana niba kanseri yarakwirakwiriye mu turemangingo tworoshye. Ni byiza kandi mu gushaka aho amagufwa yavunitse cyangwa aho adakomeye.
• Gupima PET: Gupima PET bikoresha ikintu cyitwa tracer kugira ngo hamenyekane uturemangingo twa kanseri mu mubiri wose. Bishobora gufasha kubona sarcoma ya spindle cell. Ushobora kandi gupima PET kugira ngo urebe uko ubuvuzi bwawe bukora. Ariko, gupima PET ntibikoreshwa ku bwoko bwose bwa sarcoma. Muganga wawe ni we uzagena niba gupima PET bikubereye.

Gupima amaraso

Nta gipimo cy’amaraso cyihariye gishobora gupima sarcoma y’uturemangingo tw’umugongo. Ariko, ibipimo by’amaraso bitanga amakuru y’ingenzi ku buzima bwawe, kandi ni ngombwa ko muganga wawe amenya ayo makuru. Muri rusange, ibipimo by’amaraso bishobora gutanga amakuru ku bintu nka:

• Uturemangingo tw'amaraso yawe
• Imikorere y'ingingo
• Urugero rwa enzyme (enzyme ni imiti ifasha ingingo gukora ibikorwa by'ingenzi)

Isuzuma ry'ibinyabuzima

Uburyo bwiza bwo kumenya neza niba ikibyimba ari kanseri ni ugukora biopsy. Ni bwo buryo bwonyine bwo kumenya ubwoko bwa kanseri n'urwego rwayo. Mu gihe cyo gukora biopsy, umuganga afata urugero rw'uturemangingo tw'umubiri two muri iki kibyimba akatwohereza muri laboratwari kugira ngo basuzume uturemangingo.

Abantu benshi barwaye spindle cell sarcoma bagira biopsy y'urushinge. Abaganga bashyiramo ibinure ku mubiri ukikije ikibyimba hanyuma bagakoresha urushinge ruto rufite umwobo kugira ngo bafate icyitegererezo. Kugira ngo umuganga amenye neza aho ugomba gushyira urushinge mu mubiri wawe, ushobora no gukenera gupimwa X-ray cyangwa CT scan.

Ese indwara ya spindle cell sarcoma ivurwa ite?

Uburyo uvurwa buzaterwa n'ubuzima bwawe, aho uherereye, ingano, amanota, n'ibindi bintu. Biterwa kandi no kuba uvurwa bwa mbere cyangwa niba kanseri yagarutse nyuma yo kuvurwa (isubira).

Kubaga

Intego yo kubagwa ni ugukuraho ikibyimba mu gihe hashobora kubungabungwa igufwa ryawe uko bishoboka kose. Iyo ibimenyetso byose bya kanseri mu kibyimba cy’ibanze n’ibibyimba bya kabiri bishobora gukurwaho, kanseri ishobora gukira. Ariko, iyo kanseri imaze gukwirakwira ikarenga ikibyimba cy’ibanze, biragoye cyane kuyikuraho burundu.

Ubuvuzi bwa Chimiotherapie

Chimiotherapie ni uburyo bwo kuvura bukoresha imiti yica uturemangingo twa kanseri mu mubiri wose. Ushobora guhabwa imiti ya chimiotherapie mbere yo kubagwa kugira ngo ugabanye ikibyimba kandi byoroshye kuyikuraho. Cyangwa, ushobora guhabwa imiti ya chimiotherapie kugira ngo wice uturemangingo twa kanseri dusigaye nyuma yo kubagwa. Chimiotherapie ikoreshwa kandi nk '"ubuvuzi bwo kugabanya ububabare". Nubwo idashobora gukiza kanseri, imiti ya chimiotherapie ishobora kwica uturemangingo twa kanseri kugira ngo igabanye ibimenyetso nk'ububabare bw'amagufwa.

Abantu benshi bahabwa imiti ivanze ya chimiotherapie kugira ngo ubuvuzi burusheho kugira akamaro. Bitewe n'uko urimo kuvurwa bwa mbere, niba utari kwakira neza imwe mu miti ya chimiotherapie, cyangwa niba kanseri yagarutse nyuma yo "kuruhuka", ushobora guhabwa indi miti ya chimiotherapie. "Kuruhuka" bivuze ko kanseri yakize cyangwa yashize burundu nyuma yo kuvurwa.

Ubuvuzi bushingiye ku mirasire

Ubuvuzi bwo mu kirere bw’izuba (EBRT) bukoresha imashini iyobora X-ray kuri iki kibyimba kugira ngo cyice uturemangingo twa kanseri. Niba udashobora kubagwa, ubuvuzi bukoresha imirasire bushobora gutangwa kugira ngo busenye ikibyimba. Hari igihe umuganga w’inzobere mu kubaga ashobora kudashobora kugera kuri iki kibyimba mu buryo bwo kubaga. Gishobora kuba kiri mu gice cy’umubiri cyangwa cyegereye cyane ingingo z’ingenzi ku buryo kidashobora gukurwaho neza. Muri ibyo bihe, ushobora guhabwa ubuvuzi bukoresha imirasire.

Kimwe na chemotherapy, ubuvuzi bushingiye ku maraso bushobora kandi kugabanya ibimenyetso mu gihe kanseri idashobora gukira.

Ni izihe ngorane cyangwa ingaruka mbi z'ubuvuzi?

Ni ibisanzwe kugira ingaruka mbi zikomoka ku miti ya chimiotherapie n'imirasire mu gihe cyo kuvurwa kanseri. Izi ngaruka zishobora kumara igihe runaka nyuma y'uko ubuvuzi burangiye. Ni ngombwa kubaza muganga wawe ingaruka mbi zishobora kubaho, bitewe n'ubuvuzi urimo guhabwa.

Ni ryari ngomba kubonana na muganga wanjye?

Muganga wawe azakubwira inshuro ugomba kujya kwivuza, cyangwa gupimwa kugira ngo arebe niba kanseri ikiri mu "korohera." Abantu benshi barwaye kanseri bari mu korora bazakenera kujya kwa muganga kenshi mu ntangiriro. Uko umara igihe kirekire udafite kanseri, umubare w'abazagukurikira kugira ngo barebe niba izongera kugaruka uzagabanuka.

Ni ubuhe buryo bwo gukurikirana indwara nkeneye?

Bitewe n'ingano y'amagufwa umuganga yagombaga gukuraho, ushobora gukenera ubundi buryo bwo kuyakoresha. Ubu buryo bufasha mu gukomeza imikorere y'amagufwa. Urugero, ushobora gukenera guterwa amagufwa. Terwa amagufwa rikubiyemo gusimbuza ingirangingo zakuweho n'izindi ngingo zo mu kindi gice cy'umubiri wawe cyangwa izivuye ku muntu waguhaye. Ushobora kandi gukenera urwego rw'umubiri rw'ubukorano. Ushobora gukenera ubundi buryo bwo kuyakoresha kugira ngo bigufashe kumenyera izi mpinduka.

Ni ibihe bibazo ngomba kubaza muganga wanjye ku bijyanye na spindle cell sarcoma?

Dore ibibazo by'ingenzi ugomba kubaza muganga wawe:

• Kanseri iri he?
• Icyiciro/urwego rwa kanseri ni ikihe?
• Ni gute icyo cyiciro/urwego rw'ubuvuzi bigira ingaruka kuri gahunda yanjye yo kuvurwa?
• Ni izihe ngaruka mbi zo kuvurwa nkwiye kwitega?
• Ese kanseri yanjye ishobora gukira?
• Intego z'ubuvuzi ni izihe?
• Ese ushobora kunhuza na serivisi zo kwita ku barwayi ba kanseri kugira ngo zimfashe guhangana n'indwara yanjye?

Ese sarcoma y'ingirabuzimafatizo ishobora kuvurwa? Ni ikibazo gikomeye kingana iki?

Iyo ibimenyetso byose bya kanseri bishoboye gukurwaho, abaganga bashobora kuvura spindle cell sarcoma. Spindle cell sarcoma itarakwirakwira hirya y’aho yari isanzwe ivura biroroshye cyane. Ariko, kuvura sarcoma zakwirakwiriye biragoye cyane . Metastatic Spindle Cell Sarcoma ntikunze kuvurwa.

Ubwoko bw'iyi kanseri akenshi buba 'bwiza cyane'. Ibi bivuze ko ikura vuba kandi igakwirakwira vuba. Nyuma yo koroherwa, birashoboka cyane ko igaruka, rimwe na rimwe ahantu hamwe aho ikibyimba cya mbere cyari kiri, rimwe na rimwe ahantu hatandukanye.

Ariko ibuka ko indwara ya kanseri yose iratandukanye. Muganga wawe ashobora kukubwira ingaruka zishobora guterwa n’ubuvuzi (prognosis) bitewe n’ubwoko bwihariye bwa kanseri ufite, aho igeze, ubuzima bwawe muri rusange, uko witwara mu kuvurwa, n’ibindi bintu bitandukanye. Muganga wawe ni we muntu mwiza wo kukugira inama ku buryo iyi ndwara izakugiraho ingaruka.

Ibintu dukwiye kwibuka muri iyi nkuru (Ubutumwa bwo kujyana mu rugo)

Gupimwa Spindle Cell Sarcoma bishobora kugutera stress. Iyi ndwara ishobora gutuma wumva unaniwe kandi umerewe nabi. Ubuvuzi bukunze kuba bukomeye, kandi ushobora guhura n'ibibazo nko kumenyera igufwa cyangwa urwego rw'umubiri rw'ubukorano.

Kubwibyo, ni ingenzi cyane kugirana ikiganiro cy’ukuri kandi gifunguye na muganga wawe kuva mu ntangiriro. Muri ubu buryo, ushobora gusobanukirwa indwara yawe, urugero kanseri yawe ishobora gukira, intego z’ubuvuzi bwawe, n’impinduka mu mibereho yawe uzakenera gukora mu gihe cyo kuvurwa no gukira.

Sarcoma ya Spindle cell ni kanseri ikomeye kandi ikura vuba. Ariko, hari uburyo bwo kuvura bushobora kugenzura imikurire yayo, rimwe na rimwe, ikayikiza burundu. Vugana na muganga wawe icyo ushobora kwitega. Ntugacike intege. Gukurikiza inama z'abaganga zikwiye no kugumana icyizere ni ingenzi cyane muri uru rugamba.

Sarcoma ya Spindle Cell, Sarcoma ya Spindle Cell, Kanseri, Kanseri y'amagufwa, Kanseri y'imitsi yoroshye, Ikibyimba, Ibimenyetso, Uburyo bwo kuvura