Tose tinosangana nekuchinja kudiki uye kusagadzikana mumiviri yedu nguva nenguva, handiti? Pamwe ibundu diki mumutsipa, kana kuti rinogona kunge riri chinhu chakafanana nekunzwa kuneta pasina chikonzero, kana kunzwa nyota nguva dzese. Kunyangwe zvinhu izvi zvisiri zvekunetseka nazvo, mune zvisingawanzoitika, zvinogona kunge zviri zviratidzo zvikuru zvechirwere. Nhasi tichataura nezverudzi rwekenza rusingawanzoitiki, asi zvakakosha kuti isu tese tizive nezvayo. Iyoyo ikenza inokura mumagland eparathyroid, anonzi parathyroid cancer , kana `(Parathyroid Carcinoma)`.
Chii chinonzi Parathyroid Cancer?
Zvichitaurwa zviri nyore, kenza yeparathyroid rudzi rwekenza isingawanzoitiki inokura mumatishu eparathyroid glands. Parathyroid glands yako inowanzo kuwanikwa kuseri kwethyroid gland yakaita seshavishavi iri pamberi pemutsipa wako.
Gomarara reParathyroid harina kuiswa muzvikamu zvina ("system yemazita ezvikamu zvina") semamwe marudzi egomarara. Asi, vanachiremba vanopatsanura gomarara iri muzvikamu zvitatu zvikuru:
- Kuwanikwa: Izvi zvinoreva kuti kenza iri mugland rako reparathyroid chete. Dzimwe nguva inogona kunge yakapararira zvishoma kune tissue yakapoteredza. Izvi zvinoreva kuti kenza ichiri munzvimbo imwe chete.
- Kupararira kwegomarara: Apa ndipo apo gomarara rapararira kune dzimwe nhengo dzemuviri wako, dzakadai sema lymph nodes, chiropa, mapapu, mapfupa, kana pancreas. Pakati pe10% ne30% yevanhu vane gomarara reparathyroid vanopararira negomarara (metastatic) panguva yekuongororwa. Nzvimbo dzinonyanya kuwanikwa mapapu, mapfupa, kana chiropa.
- Kudzokorora: Apa ndipo panodzoka kenza mushure mekurapwa kwekutanga - kazhinji mushure mekunge gland rekenza rabviswa. Vanhu vanopfuura hafu vane kenza yeparathyroid vanozove nerudzi urwu rwekenza. Kenza inowanzo dzoka mukati memakore maviri kusvika mashanu ekuvhiyiwa kwekutanga. Zvisinei, dzimwe nguva inogona kudzoka mushure memakore makumi maviri.
Ndezvipi izvi zvinonzi parathyroid glands?
Vazhinji vedu tine magland mana eparathyroid akakura sepizi. Sezvambotaurwa, aya ari kuseri kwegland rethyroid. Kufanana negland rethyroid, magland eparathyroid chikamu chehurongwa hwe endocrine yako. Dzimwe nguva, magland aya eparathyroid anogona kuwanikwa padyo negurokuro rako kana kunyange muchipfuva chako. Izvi zvinonzi ectopic.Matinji eparathyroid anonzi parathyroid glands, zvinoreva kuti haasi panzvimbo yaanofanira kunge ari.
Basa guru remagland ako eparathyroid nderekudzora huwandu hwecalcium muropa rako nekugadzira parathyroid hormone (PTH) . Dzimwe nguva, rimwe kana akawanda emagland ako eparathyroid anotanga kugadzira parathyroid hormone yakawandisa (PTH). Chirwere ichi chinonzi Primary Hyperparathyroidism (pHPT) . Kana PTH yakawandisa ikaburitswa, huwandu hwecalcium muropa rako hunowedzera. Chirwere ichi chinonzi hypercalcemia .
Ndeupi musiyano uripo pakati pekenza yeparathyroid neparathyroid adenoma?
Parathyroid adenoma kukura kusina njodzi, kusiri kenza muparathyroid gland. Zvisinei, parathyroid gomarara kukura kwemasero ane kenza, asiri kenza munyama yako yeparathyroid. Pazvirwere zvine chekuita neparathyroid glands, parathyroid adenoma yakajairika kupfuura parathyroid gomarara.
Asi hechino chinhu chakakosha: Mumamiriro ese aya, kenza yeparathyroid neparathyroid adenoma, parathyroid gland yako inogona kushanda zvakanyanya uye kugadzira parathyroid hormone yakawandisa (PTH). Zvadaro, sezvambotaurwa, hypercalcemia inoitika. Hypercalcemia iyi inogona kukuvadza muviri wako nehutano hwako. Saka, kurapwa kwakajairika kwekenza yeparathyroid, pamwe neparathyroid adenomas, kubvisa parathyroid gland iri kushanda zvakanyanya.
Kunyangwe kuna vanachiremba, zvinogona kuoma kuziva nekukurumidza kana iri parathyroid adenoma kana parathyroid carcinoma. Nekuti masero ese ari maviri anogona kutaridzika akafanana, mushure mekunge parathyroid gland inoshanda zvakanyanya yabviswa nekuvhiyiwa, bvunzo dzakawanda dzinodiwa kuti dzisimbise kana iri adenoma kana carcinoma.
Chii chinonzi hypercalcemia? Zvinoenderana sei nekenza yeparathyroid?
Hypercalcemia inguva apo huwandu hwecalcium muropa rako huri pamusoro pezvakajairika. Vanhu vane kenza yeparathyroid vanowanzova nehypercalcemia. Izvi zvinokonzerwa nekuti kenza inoita kuti parathyroid gland yako ishande zvakanyanya uye igadzire parathyroid hormone yakawandisa (PTH). Parathyroid hormone (PTH) inodzora huwandu hwecalcium muropa rako. Saka, kana uine parathyroid hormone yakawandisa (PTH), huwandu hwecalcium muropa rako huchawedzera.
Kukwira kwecalcium mumuviri kunogona kukuvadza hutano hwako nemuviri. Saka, zvakakosha zvikuru kurapa hypercalcemia inokonzerwa nekenza yeparathyroid pamwe chete nekenza pachayo.
Kune mhando dzakasiyana dzekenza yeparathyroid here?
Ehe, kune mhando mbiri huru dzegomarara reparathyroid.
1. Rudzi rwakajairika: Muchiitiko ichi, masero egomarara anokonzera kuti parathyroid gland yako igadzire parathyroid hormone (PTH) yakawandisa uye igoiburitsa muropa. Izvi zvinoita kuti calcium muropa rako ikwire.
2. Kansa yeparathyroid isingashande: Iyi inonziwo "kansa yeparathyroid isingabudisi" (non-secreting parathyroid carcinoma). Izvi zvakasiyana nedzimwe mhando. Nekuti, vanhu vane rudzi urwu rwekenza havana huwandu hwakakwira hweparathyroid hormone (PTH) kana calcium muropa ravo. Rudzi urwu haruwanzoitiki, rwunowanikwa muvanhu vasingasviki 10% vevarwere vane kenza yeparathyroid.
Kana kenza yeparathyroid yaonekwa, bvunzo dzinoitwa kuti dzionekwe kana iri panzvimbo , yakapararira , kana kuti yakadzokororwa . Sezvambotaurwa, kupatsanurwa kwezvikamu zvina kunoshandiswa kune mamwe makenza hakushandiswi pakuita izvi.
Ndiani ane mukana mukuru wekuwana kenza yeparathyroid?
Gomarara iri rinobata vakadzi nevarume zvakaenzana. Rinowanzoonekwa kuvanhu vane makore anopfuura makumi matatu .
Chirwere ichi chakajairika zvakadii?
Kenza yeparathyroid chirwere chisingawanzoitiki. Ingofungai, inongokonzera 0.005% yekenza dzese. Uyewo, kenza yeparathyroid inokonzeresa pakati pe0.5% ne1% yezvirwere zvese zvine chekuita neparathyroid gland. Saka, izvi hazviwanzoitiki.
Ndezvipi zvinokonzera Parathyroid Cancer?
Kutaura zvazviri, hapana chikonzero chaicho chekenza yeparathyroid chakawanikwa.
Zvisinei, zvinotevera zvirwere zvisingawanzoitiki zvemajini (kureva, zvakatorwa kubva kumhuri) zvinoonekwa sezvikonzero zvinokonzera kenza iyi:
- Matambudziko emudumbu akawanda emhando yekutanga (MEN1)
- Kurwara kweparathyroid kwakabatana nemhuri (FIHP)
- Hyperparathyroidism-jaw bundu syndrome
Uyezve, kana wakamborapwa nemwaranzi mumusoro kana mumutsipa wako kare, zvinogonawo kuwedzera njodzi yako yekubatwa nekenza yeparathyroid.
Ndezvipi zviratidzo zveParathyroid Cancer?
Kazhinji, zviratidzo zvegomarara reparathyroid zviratidzo zvehypercalcemia zvinobuda. Zviratidzo nezviratidzo zvehypercalcemia zvinogona kusanganisira:
- Kuda kuita weti kakawanda kupfuura zvakajairika (kunyanya kuita weti)
- Kunzwa nyota kupfuura nguva dzose
- Kusvotwa nekurutsa
- Senguva dzoseKusanzwa nzara
- Kuzvimba
- Kunzwa kuneta zvakanyanya
- Kunzwa sekunge wakaora mwoyo
- Kukanganwa kana kurasikirwa nendangariro
- Kurwadziwa kwetsandanyama, kushaya simba, uye/kana kukamhina
Zvimwe zviratidzo zvinogona kuitika zvekenza yeparathyroid:
- Kuva nebundu mumutsipa
- Kuchinja kwezwi kana kurira
- Kuoma kumedza chikafu
Kana uine chimwe chezviratidzo izvi kana kupfuura, usatya kufunga kuti igomarara reparathyroid. Zviratidzo izvi zvinogona kuonekwawo mune zvimwe zvirwere zvakawanda. Zvisinei, kana chimwe chinhu chakadai chikaramba chiripo, zvakanaka kuona chiremba kuti akupe mazano.
Kenza yeParathyroid inoonekwa sei?
Kuziva kenza yeparathyroid dzimwe nguva kunogona kuoma. Chimwe chikonzero ndechekuti masero eparathyroid adenoma isiri kenza neaya ekenza yeparathyroid anogona kufanana.
Kenza yeparathyroid inowanzoonekwa mushure mekunge parathyroid gland yako isingawanzoitiki, inoshanda zvakanyanya yabviswa nekuvhiyiwa (kuvhiyiwa kweparathyroidectomy), uye nyama yacho yoongororwazve. Dzimwe nguva, chiremba anogona kuona kenza yeparathyroid panguva yekuvhiyiwa.
Ndedzipi bvunzo dzinoitwa kuti dziongororwe chirwere?
Sezvambotaurwa, kenza yeparathyroid inowanzoonekwa mushure mekunge waonekwa kuti une primary hyperparathyroidism , uye parathyroid gland isingawanzoitiki, inoshanda zvakanyanya inobviswa nekuvhiyiwa. Dzimwe nguva, chiremba anogona kuona kenza yeparathyroid panguva yekuvhiyiwa.
Usati wavhiyiwa kubvisa parathyroid gland yako inokanganisa zvakanyanya, unogona kuedzwa seizvi:
- Kuongororwa kwecalcium muropa
- Kuongororwa kwePTH yeropa
- Kuongororwa kweparathyroid - Uku kunowanzoitwa ne radioactive sestamibi scan uye/kana CT scan.
Kana ukaonekwa uine kenza yeparathyroid, chiremba wako anogona kuraira bvunzo dzemifananidzo dzakadai kuti aone kana kenza yapararira (yakaita metastasized) kune dzimwe nhengo dzemuviri wako:
- CT scan (computerized tomography scan): CT scan inoshandisa X-rays nekombiyuta kugadzira mifananidzo yakawanda yemuviri wako ine mativi matatu (3D).
- Kuongororwa kweMRI (MRI - magnetic resonance imaging):Kuongororwa kweMRI kunoshandisa magineti makuru, mafungu eredhiyo, nekombiyuta kugadzira mifananidzo yakadzama yemuviri wako. Haishandisi X-ray (radiation).
Ndeipi mishonga yekurapa kenza yeparathyroid?
Nzira huru yekurapa kenza yeparathyroid ndeyekuvhiyiwa kubviswa kwegomarara reparathyroid (`en bloc resection`). Kana gomarara reparathyroid rapararira (rapararira), chiremba wako angangodawo kubvisa nyama yakatenderedza gomarara rako reparathyroid kana nyama yegomarara kubva kune dzimwe nhengo dzemuviri wako.
Nzira dzinotevera dzekuvhiya dzinogona kushandiswa pakurapa kenza yeparathyroid:
- Kubviswa kwemasero eropa: Mukuita uku, chiremba anobvisa parathyroid gland yako yese pamwe nekapisi yakaipoteredza. Dzimwe nguva, vanogona kubvisa hafu yethyroid gland iri kudivi rimwe chete nekenza parathyroid gland, pamwe chete nenyama, tsandanyama, uye tsinga dzakaipoteredza.
- Kubvisa bundu: Mukuita uku, chiremba anovhiya anobvisa bundu rakawanda sezvinobvira. Mamwe mabundu anogona kusabviswa zvachose.
- Kubviswa kwemasero eropa: Mukuita izvi, chiremba anobvisa chero kenza yakapararira (yakapararira) kune dzimwe nyama uye/kana nhengo dzemuviri wako, semuenzaniso, mapapu.
Ndichapihwa chemotherapy here kana radiation therapy?
Kurapa nemwaranzi hazviwanzo shandiswa kurapa kenza yeparathyroid. Chiremba wako ndiye achasarudza kana chemotherapy uye/kana radiation therapy iri sarudzo yakakodzera kwauri.
Pane mushonga wekenza yeparathyroid here?
Parizvino, hapana mishonga chaiyo yekurapa kenza yeparathyroid. Vanhu vazhinji vane kenza yeparathyroid vanowana zviratidzo zve hypercalcemia. Nekuti hypercalcemia inogona kukuvadza, chiremba wako anogona kukupa imwe kana kupfuura yemishonga inotevera ye hypercalcemia:
- Cinacalcet (Cinacalcet - Sensipar®)
- MaBisphosphonates
- Denosumab (Denosumab - XGEVA®)
Kana uine zviratidzo zvakakomba zve hypercalcemia, chiremba wako anogona kukukurudzira kuti uende kuchipatara nekukasika wotanga kushandisa mvura yemutsinga (IV) nedzimwe nzira dzekurapa.
Kenza yangu yeparathyroid inogona kudzoka here?
Ehe, vanhu vanopfuura hafu vanoonekwa vaine kenza yeparathyroid vanogona kudzoka kwekenza iyi zvakare.Gomarara rinowanzo dzoka mukati memakore mashoma - kazhinji pakati pemakore maviri nemashanu. Asi mune dzimwe nguva, rinogona kuitika kwemakumi emakore (makore makumi maviri kana kupfuura) mushure mekuongororwa kwekutanga uye kurapwa.
Ko gomarara iri rinogona kupararira (metastasize) kune dzimwe nhengo dzemuviri here?
Ehe, kenza yeparathyroid inogona kupararira (metastasize) kune dzimwe nhengo dzemuviri wako. Pakati pe10% ne30% yevanhu vane kenza yeparathyroid vanenge vatove nekenza (metastatic) panguva yekuongororwa. Muzviitiko izvi, kenza inowanzopararira kumapapu ako, mapfupa, kana chiropa. Zvisinei, inogonawo kupararira kulymph nodes kana pancreas.
Ndeipi fungidziro yekenza yeparathyroid?
Kufanotaura kuti chirwere chegomarara reparathyroid chinozoitika zvinoenderana nekuti kuvhiyiwa kwekubvisa parathyroid gland kwapera sei paunoonekwa kekutanga, sezvo nzira dzekurapa dzechipiri dzakadai seradiation therapy uye chemotherapy dzakaganhurirwa.
Kune vanhu vane kenza yeparathyroid vakavhiyiwa masero eropa uye vane margins asina kunaka, mwero wekurarama unosvika 90% mushure memakore mashanu mushure mekuvhiyiwa kwekutanga. Mwero wekurarama unosvikawo 67% mushure memakore gumi mushure mekuvhiyiwa kwekutanga.
Vanhu vanopfuura hafu vanoonekwa vaine kenza yeparathyroid uye vachivhiyiwa kubvisa gland vachasangana nekenza inodzoka zvakare. Muzviitiko izvi, kenza inowanzo dzoka mukati memakore maviri kusvika mashanu mushure mekuvhiyiwa kwekutanga. Zvisinei, inogona kudzoka mushure memakumi emakore.
Kenza yeParathyroid inogona kudzivirirwa here?
Zvinosuwisa kuti hapana nzira inozivikanwa yekudzivirira kenza yeparathyroid. Zvakare, hapana nzira yekuderedza njodzi yekubatwa nechirwere ichi. Kana paine munhu mumhuri yako akambova nematambudziko eparathyroid gland, zvakanaka kutaura nachiremba wako.
Mibvunzo ipi yandinofanira kubvunza chiremba wangu?
Kana uine kenza yeparathyroid, ungada kubvunza chiremba wako mibvunzo yakaita seiyi:
- Ko kenza yapararira kupfuura parathyroid gland yangu here?
- Ndeipi nzira yakanakisisa yekurapa kenza yeparathyroid?
- Ndezvipi njodzi nemigumisiro yekurapwa?
- Mhuri yangu iri panjodzi yekubatwa nekenza yeparathyroid here?
- Ndingawana kenza yeparathyroid zvakare here?
- Ndiri panjodzi yekubatwa nedzimwe mhando dzekenza here?
- Ndichazoda rubatsiro rupi rwekutevera mushure mekurapwa?
- Ndinofanira kuziva zviratidzo zvematambudziko here?
Pakupedzisira, zvinhu zvekurangarira
Kuonekwa uine kenza kunogona kutyisa. Asi yeuka,Chikwata chenyu chezvekurapa chiripo kuti chikubatsirei uye chikuratidzei nzira yakanakisisa yekurapa. Kunyangwe kuvhiyiwa kuri iko chete kurapwa kwegomarara reparathyroid, tsvakurudzo nekurapa gomarara zviri kuramba zvichivandudzika. Panogona kunge paine bvunzo yekiriniki yamunogona kutora chikamu mairi. Saka, musatya kubvunza chiremba wenyu mibvunzo nezvegomarara renyu reparathyroid. Ita shuwa kuti zvese zvinotsanangurwa nenzira yamunonzwisisa.
` Kenza yeParathyroid, Parathyroid Glands, Hypercalcemia, Parathyroid Hormone, PTH, Zviratidzo zveKenza, Kurapwa kweKenza, Kuvhiyiwa
💬 Comments (0)
Hapana zvakataurwa parizvino. Isa mhinduro yako pano kekutanga.
Wedzera zvaunofunga