Wakambonzwa kupisa kusingatsungiririki kana maronda paganda rako paunobuda muzuva here? Kana kuti wakamborwadziwa nemudumbu zvakanyanya pamwe nekusvotwa uye kurutsa pasina chikonzero chakajeka here? Zviratidzo izvi zvakasiyana nezvirwere zvakajairika. Pamwe kuseri kweizvi kune chirwere chisingawanzoitiki icho vanhu vazhinji vasati vatombonzwa nezvacho. Icho chirwere chimwe chakadai chinonzi Porphyria . Usatye kana ukanzwa zita iri. Nhasi, tichataura nezvazvo zviri nyore uye nenzira yaunogona kunzwisisa.
Zvichitaurwa zviri nyore, chii chinonzi Porphyria?
Kuti tinzwisise izvi, ngatitangei tafunga nezvefekitari diki mumuviri wedu. Kune puroteni inokosha zvikuru inopa masero edu matsvuku eropa ruvara rwawo rutsvuku uye inotakura okisijeni kubva mumapapu kuenda kumuviri wese. Inonzi 'heme'. Heme iyi inogadzirwa mumuviri wedu mumatanho akatevedzana, semutsetse wekubatanidza. Sekunge kuunganidza mota. Padanho rega rega, mapuroteni akakosha anonzi ma enzymes anoshanda.
Fungidzira, chii chinoitika kana danho rimwe chete muchikamu ichi chekugadzira rikabatwa, kana kana mushandi mumwe chete (enzyme) akasashanda nemazvo? Danho rinotevera harigone kugadzirwa, uye zvinhu zvakagadziriswa zvikaungana, handiti? Saizvozvowo, kana paine chikanganiso padanho rekugadzirwa kweheme, makemikari akagadzirwa padanho rekare, anonzi 'porphyrins' uye 'porphyrin precursors', anotanga kuungana mumuviri. Kuunganidzwa kwemakemikari aya mumuviri ndiko kunokonzera zviratidzo zveporphyria. Izvi zvinogona kukuvadza sisitimu yetsinga kana ganda.
Ichi chirwere chinowanzo itika mumajini chinowanikwa mumhuri. Asi musazvidya mwoyo, hazviwanzoitiki. Uye ikozvino kune nzira dzakanaka dzekurapa chirwere ichi.
Ndeapi marudzi makuru eporphyria?
Porphyria inogona kukamurwa kuita mapoka maviri makuru, zvichienderana nekuti zviratidzo zvinoonekwa sei. Kunzwisisa kupatsanurwa uku kuchakubatsira kunzwisisa chirwere zviri nani.
| Rudzi | Yakanyanya kukanganiswa | Zviratidzo zvakajairika |
|---|---|---|
| Porphyria Yakanyanya | Kuhurongwa hwetsinga | Dzimwe nguva kurwadziwa kwakanyanya mudumbu, kuda kurutsa, kurutsa, kurwadziwa muchipfuva, kurova kwemoyo kwakanyanya, kuvhiringidzika kwepfungwa, pfari. |
| Porphyria yeganda | Kuganda | Kunzwa chiedza chezuva, kusviba kweganda rinoonekwa nezuva (maoko, kumeso, mutsipa), kukwenya ganda zviri nyore, kuchinja kweruvara rweganda. |
Kune mamwe marudzi akasiyana-siyana pasi pemhando mbiri idzi huru. Semuenzaniso, rudzi runonzi `Acute Intermittent Porphyria (AIP)`, runowira pasi peacute porphyria, uye rudzi runonzi `Porphyria Cutanea Tarda (PCT)`, runowira pasi pecutaneous porphyria, haruwanzoitiki.
Ndezvipi zvinokonzera zviratidzo?
Kunyangwe porphyria iri majini, zviratidzo hazviwanzoonekwa. Pane zvimwe zvinhu zvinogona kukonzera zviratidzo, kana "kurwiswa". Izvi zvinonzi 'zvinokonzera'. Kudzivisa izvi ndiyo nzira yakanakisisa yekugadzirisa chirwere ichi.
- Mimwe mishonga: Mimwe mishonga inoderedza marwadzo , mapiritsi ekudzivirira pamuviri, mishonga inonyaradza marwadzo, uye mimwe mishonga yepfari zvinogona kukonzera izvi. Kana uine porphyria, unofanira kutaura nachiremba wako usati watora chero mushonga.
- Doro nekusvuta : Kunwa doro zvakanyanya nekusvuta, kunyanya panguva imwe chete, ndizvo zvinonyanya kukonzera dambudziko iri.
- Kudya uye kutsanya: Zvinhu zvakaita sekudya zvine makabhohaidhiretsi mashoma , kudya kwakasimba kwekudzikisa huremu, uye kutsanya zvinogona kukonzera zviratidzo.
- Kushushikana kwepfungwa nemuviri: Zvinhu zvakaita sekushanda zvakanyanya, kushushikana kwepfungwa, uye kuvhiyiwa zvinogona kukanganisa.
- Utachiona: Zviratidzo zvinogona kuitika nekuda kwekushushikana kunoiswa mumuviri nechirwere chipi zvacho kana hutachiona.
- Chiedza chezuva: Chiedza chezuva ndicho chinokonzera chirwere cheCutaneous Porphyria kuvanhu vane chirwere ichi.
Unofanira kuona chiremba riini? Kuongororwa kwechirwere kunoitwa sei?
Nekuti chirwere ichi hachiwanzoitiki uye zviratidzo zvacho zvakafanana nezvimwe zvirwere zvakajairika, dzimwe nguva zvinotora nguva kuti zviongororwe. Zvakakosha kuona chiremba kana uine chimwe chezviratidzo zvinotevera, kunyanya kana zvichiitika kakawanda.
Mu porphyria yakaoma
Kana uchinzwa kurwadziwa kwakanyanya mudumbu pamwe chete nezviratidzo zvakaita sekusvotwa, kurutsa, kuvimbiwa, kurova kwemoyo kwakanyanya, BP, kushaya simba kwetsandanyama, kuvhiringidzika, kana pfari, zvakakosha zvikuru kuenda kuchipatara nekukasika, kunyanya kuEmergency Treatment Unit (ETU), sezvo chirwere ichi dzimwe nguva chinogona kuisa hupenyu panjodzi.
MuCutaneous Porphyria
Kana ganda rako rikaita maronda, maronda, kuzvimba, kutsvuka, kana kukwenya zviri nyore mushure mekupiswa nezuva, enda kuna chiremba weganda.
Maitiro ekuongorora chirwere:
1. Kuongororwa nachiremba: Kutanga, chiremba achakuongorora, achinyatsoteerera zviratidzo zvako uye nhoroondo yezveutano hwemhuri yako.
2. Kuongororwa kwemurabhoritari: Kana paine chifungidziro chekuti porphyria inowanikwa, weti yako, ropa, uye pamwe sampuli dzetsvina yako zvichaongororwa kuti uone huwandu hweporphyrins. Muzviitiko zvakakomba, weti inogona kuchinja ruvara rutsvuku kana kuti rwepepuru.
3. Kuongororwa kweMajini: Kana chirwere chikasimbiswa nekuongororwa kwerabhoritari, kuongororwa kwemajini kunogona kuitwa kuti paonekwe shanduko chaiyo yemajini yakachikonzera.
Ndezvipi zvingasarudzwa pakurapa?
Kurapa porphyria kunosiyana zvichienderana nerudzi rwechirwere uye kuoma kwezviratidzo. Kunyangwe pasina mushonga, zviratidzo zvinogona kudzorwa uye hupenyu hwemazuva ese hunogona kuraramwa.
Kurapa kweAcute Porphyria
Kana zviratidzo zvanyanya kuipa (kurwiswa kwakanyanya), zvinodikanwa kuti munhu apinde muchipatara uye arapwe.
- Kupa mvura ine munyu (IV fluids): Kuenzanisa munyu nemvura mumuviri.
- Jekiseni reHeme: Kudzora kushomeka kweheme mumuviri uye kuderedza huwandu hweporphyrin inoungana.
- Kupa shuga: Kupa shuga dzakadai sedextrose netsinga kana nemuromo kunopa chiratidzo chechiropa kuti chideredze kugadzirwa kweporphyrin.
- Mamwe marapirwo: Mishonga inonyaradza marwadzo anorwadza zvakanyanya, uye mishonga yekurutsa nekurutsa.
- Mishonga mitsva yakaita seGivosiran (Givlaari): Kune vanhu vane zviratidzo zvinowanzoonekwa, mushonga uyu unopihwa mwedzi wega wega kuderedza kuwanda kwawo uye kuoma kwawo.
Kurapa kweCutaneous Porphyria
- Kudzivirira zuva:Ichi ndicho chinhu chakakosha. Kupfeka maoko marefu, ngowani, uye kushandisa mafuta ekudzivirira zuva ane dziviriro yepamusoro, senge SPF 50+, kwakakosha.
- Kuvhiyiwa kwemasero eropa: Izvi zvinosanganisira kubvisa ropa shoma (rinenge rimwe chete) mumuviri mavhiki mashoma ega ega. Izvi zvinobatsira kuderedza huwandu hwesimbi yakawedzerwa mumuviri uye zvinobatsira kubvisa maporphyrins akaungana muchiropa.
- Mishonga: Mishonga mishoma yakaita sechloroquine kana hydroxychloroquine inogona kukurumidzisa kubviswa kweporphyrins muchiropa.
Chinhu chinonyanya kukosha ndechekugara uchitaurirana nachiremba wako uye kutevedzera mirairo yake nemazvo. Kana vanachiremba vako vachiziva kuti une porphyria, zvichabatsira zvikuru pakupa kurapwa kwakakodzera panguva yekukurumidzira.
Mharidzo Yekuenda Nayo Kumba
- Porphyria iboka rezvirwere zvisingawanzoitiki zvinokonzerwa nekusakwana kwemajini kwakabatana nekugadzirwa kweheme mumuviri.
- Kune mhando mbiri huru: rudzi rweacute, runokanganisa tsinga, uye rudzi rweganda, runokanganisa ganda.
- Kuziva nekudzivirira zvinhu zvinogona kukonzera zviratidzo zvechirwere kwakakosha pakurapa chirwere ichi. Doro, kusvuta, mimwe mishonga, uye kutsanya ndizvo zvinhu zvikuru zvinokonzera chirwere ichi.
- Tsvaga rubatsiro rwechiremba nekukasika kana uine zviratidzo zvakakomba zvakaita sekurwadziwa mudumbu uye kurutsa. Enda kuna chiremba weganda kana uine maronda paganda uye uchinzwa kusviba kwezuva.
- Kunyangwe ichi chiri chirwere chehupenyu hwese, kana ukachirapa zvakanaka uye ukachinja mararamiro ako, chinogona kurapwa zvakanaka uye unogona kurarama hupenyu hwakajairika. Gara uchitevera mirairo yachiremba wako.
👩🏽⚕️ Mibvunzo yekuwedzera (Mibvunzo Inowanzo bvunzwa)
💬 Porphyria chirwere cherudzii?
Porphyria chirwere chemumajini (chenhaka) umo makemikari akasiyana anoungana mumuviri nekuda kwekushaikwa kwekugadzirwa kwakakodzera kwechikamu chemuviri wedu chinonzi 'heme' chinodiwa kuti chigadzire ropa.
💬 Ndezvipi zviratidzo zve porphyria?
Kune mhando mbiri dzeizvi: Imwe ikurwadziwa kwakanyanya mudumbu, kurutsa, uye dzungu. Imwe ikupisa kwezuva, izvo zvinoita kuti ganda ritsvuke uye riite maronda.
💬 Chirwere ichi chinogona kurapwa zvachose here?
Zvinosuwisa kuti chirwere ichi chinokonzerwa nemajini uye hachigone kurapwa zvachose. Zvisinei, nekudzivisa kupiswa nezuva uye kutora mishonga yawakanyorerwa nachiremba wako, unogona kudzora zviratidzo zvikuru uye kurarama hupenyu hwakajairika.
💬 Comments (0)
Hapana zvakataurwa parizvino. Isa mhinduro yako pano kekutanga.
Wedzera zvaunofunga