Unowanzo sangana nemarwadzo emuviri asinganzwisisike here? Ngatidzidzei zvakawanda nezve (Systemic Mastocytosis) iyi!

Dzimwe nguva unowana mavara matsvuku, anokwenya paganda rako here? Kana kuti une kurwadziwa nemudumbu nemusoro zvinongoerekana zvapera? Kana zvinhu izvi zvikaitika kakawanda, chingave chirwere chisingawanzoitiki chinonzi ``Systemic Mastocytosis'' chatichataura nezvacho nhasi. Usazvidya mwoyo, ichi hachisi chirwere chinokanganisa vanhu vazhinji. Asi zvakakosha kuziva izvi.

Saka, chii chinonzi "Systemic Mastocytosis" iyi?

Zvichitaurwa zviri nyore, `(Systemic Mastocytosis)` chirwere chisingawanzoitika chine chekuita neropa redu. Chinoitika apa ndechekuti mhando chaiyo yesero inonzi `(Mast cells)` mumuviri wedu inokura zvisingawanzoitiki. Funga nezvazvo, maseru aya akafanana nemasoja madiki mumuviri wedu. Ndiwo, sechikamu chemuviri wedu wekudzivirira muviri, anoziva uye anorwisa vapindi vekunze (senge utachiona, allergens, nezvimwewo). Kana muvengi wekune imwe nyika akadaro auya, maseru aya anoburitsa makemikari akadai se`(Histamine)`. Uyu `(Histamine)` ndiwo unokonzera zviratidzo zvekurwara (senge kutsvuka, kuvaviwa, kuzvimba). Kazhinji, maseru ekudzivirira muviri anomira kuburitsa uyu `(Histamine)` kana basa rapera. Zvisinei, mumuviri wemunhu ane `(Systemic Mastocytosis)`, maseru aya asina kujairika anokura zvakanyanya uye anoburitsa `(Histamine)` nguva dzose. Zvakaita semunhu akasiya pombi yemvura obva akanganwa kuidzima. Ndokusaka tichiramba tichiva nezviratidzo zvakaita seallergy. Zvinogona kukanganisa kwete ganda redu chete, asiwo nhengo dzedu dzemukati senge chiropa, spleen, uye ura. Chirwere ichi, chinonzi ``Systemic Mastocytosis,'' chinonzi chinobata vanhu gumi nevatatu chete pavanhu 100,000 pasi rose. Izvi zvinoreva kuti hachiwanzoitiki. Zvisinei, vanhu vane chirwere ichi vari panjodzi huru ye anaphylaxis ( allergies dzakakomba, dzinongoerekana dzaitika, uye dzinotyisidzira hupenyu). Kashoma, ``Systemic Mastocytosis'' inogonawo kuchinja kuita kenza. Vanachiremba havagone kurapa chirwere ichi zvizere. Zvisinei, kune marapirwo anogona kukubatsira kudzora zviratidzo zvako uye kurarama hupenyu hwakajairika.

Ndedzipi mhando huru dze `(Systemic Mastocytosis)`?

Kune mhando nhanhatu huru dze "Systemic Mastocytosis". Dzinotikanganisa nenzira dzakasiyana. Kazhinji, kana uine mast cells asingawanzoitiki mumuviri wako, ndipo panogona kuva nematambudziko akawanda. Ngatitarisei kuti ndeapi marudzi iwayo: 1. Rudzi rwe "Indolent systemic mastocytosis" runokura zvishoma nezvishoma:

• Rudzi urwu ndirwo rwakajairika. Kufanana nemuti unokura zvishoma nezvishoma, zvinogona kutora makore kuti zviratidzo zvionekwe. Huwandu hwemasero emuviri asina kujairika hunowedzera nekufamba kwenguva. Izvi zvinogona kukonzera zviratidzo paganda, chiropa , spleen , uye mudumbu (kureva, muura).

2. Rudzi rwakanyanya kukwira (`Systemic smoldering mastocytosis`):

• Murudzi urwu, masero emasero asingawanzoitiki anoungana muhuwandu hwakawanda muchiropa netsvina. Nekufamba kwenguva, izvi zvinogona kukonzera kuti chiropa kana tsandanyama zvizvimbe. Funga nezvazvo sezvinoitika kana imba diki yazara nevanhu.

3. Rudzi runouya nezvimwe zvirwere zveropa (`Systemic mastocytosis ine associated hematologic neoplasm`):

• Vanhu vane rudzi urwu vanogona kuwana mamwe matambudziko ane chekuita neropa, akadai se myeloproliferative neoplasms uye myelodysplastic syndrome . Rudzi urwu runobata munhu mumwe chete pavanhu vashanu vane Systemic Mastocytosis.

4. Rudzi rwakakomba (`Aggressive systemic mastocytosis`):

• Izvi zvakanyanya kuipa nekuti zvinogona kukanganisa mupfupa (uko kunogadzirwa masero eropa) nemapfupa. Masero emhando ye mast asina kujairika anogona kukura mukati memapfupa, zvichiita kuti asave nesimba uye obva apwanyika zviri nyore.

5. Rudzi runoshanduka kuita leukemia (`Mast cell leukemia`):

• Kashoma, Systemic Mastocytosis inogona kukura kuita chirwere chinonzi Mast Cell Leukemia . Urwu rudzi rweAcute Myeloid Leukemia (AML) .

6. Rudzi rwebundu (`Mast cell sarcoma`):

• Apa ndipo apo bundu (mamota) anoumbwa kubva kumasero emuviri asina kujairika anokuvadza nhengo dzakasiyana dzemuviri. Vanhu vashoma vane ``Systemic Mastocytosis`` vanowana chirwere ichi chinonzi ``Mast cell sarcoma``.

Ndezvipi zviratidzo zvechirwere ichi (Systemic Mastocytosis)?

Zviratidzo zvinogona kusiyana kubva pamunhu nemunhu. Zvinoenderana nekuti masero emuviri asina kujairika akanyanya kuungana kupi mumuviri. Semuenzaniso, kana uine masero akawanda emuviri mudumbu mako, unogona kuva nemaronda uye kurwadziwa mudumbu. Zvakare, kana masero emuviri akaungana mumongo wako wemapfupa, zvinogona kukanganisa kugadzirwa kwemasero eropa. Heano mamwe ezviratidzo zvakajairika:

• Kushaya ropa ( anemia )
• Kurwadziwa kwemapfupa
• Kubuda ropa rakawanda (semuenzaniso, ropa rakawanda kubva paronda diki)
• Kunzwa kuneta nguva dzese (` Kuneta` )
• Ganda rakacheneswa
• Kurova kwemoyo
• Mapundu (anokwenya, akakwidibira paganda )
• Ganda rinokwenya
• Kuchinja kwemanzwiro kana kuora mwoyokuora mwoyo
• Mavara matema, anokwenya paganda (`Urticaria pigmentosa`)

Dzimwe nguva, vanhu vane Systemic Mastocytosis vanogona kusangana nezvimwe zvezviratidzo izvi panguva imwe chete. Vanachiremba vanoti izvi "mastocytosis attack" kana kuti "flare."

Zvakakosha: Haasi munhu wese ane zviratidzo izvi ane `(Systemic Mastocytosis).` Zvisinei, kana uine zvimwe zvezviratidzo izvi panguva imwe chete, uye zvikaramba zviripo, unofanira kuona chiremba kuti akupe mazano.

Sei `(Systemic Mastocytosis)` iyi ichiitika?

Ongororo yakawana kuti vanhu vanosvika 80% vane `(Systemic Mastocytosis)` vane `KIT gene variant` . Iri `KIT` gene rinobatsira mamwe marudzi emasero mumuviri wedu, kunyanya masero eropa nemasero epamusoro, kukura. Iri gene variant rinoitika mushure mekunge tabata pamuviri. Izvi zvinoreva kuti harina kugara nhaka.

Ndezvipi zvinhu zvinoomesa kana kukonzera chirwere ichi (`Zvinokonzera`)?

Zvinhu zvakawanda zvinogona kukonzera zviratidzo zve "Systemic Mastocytosis." Havasi vese vanobatwa nezvinhu zvakafanana. Zvisinei, pane zvinhu zvishoma zvakajairika:

• Doro
• Zvokudya zvinonaka
• Mimwe mishonga: Semuenzaniso , NSAIDs ( mishonga inoderedza marwadzo), mishonga inozorodza tsandanyama, uye mushonga wekurwadziwa kwemudumbu.
• Kurovedza muviri uye kuita zvemuviri ( kune vamwe chete)
• Kurumwa nezvipembenene (kunyanya masvosve, mago, nenyuchi)
• Kushungurudzika kwemuviri kana kwepfungwa
• Kukwesha kana kukwesha ganda rako
• Kuchinja kamwe kamwe kwekushisa (semuenzaniso, kungoerekana wasvetukira mumvura inotonhora)

Kana uine chirwere ichi, zvakakosha kubvunza chiremba wako kuti chii chiri kukukanganisa uye chii chaunofanira kudzivisa.

Ungaongorora sei chirwere ichi nemazvo? (Kuongororwa)

Paunoenda kunoona chiremba, chinhu chekutanga chavachaita ndechekukuongororwa kwemuviri. Vachakubvunza nezvezviratidzo zvako uye chero chirwere chawaimbova nacho. Zvadaro, vanogona kuita imwe kana kupfuura yebvunzo dzinotevera kuti vaone kana uine Systemic Mastocytosis:

• Kuongororwa kweropa: Izvi zvinoongorora huwandu hwetryptase muropa rako. Tryptase ienzyme yakakosha inoburitswa nemasero emuviri kana achipindura kune zvimwe zvinhu.
• Kuongororwa kwemapfupa: Tarisa kana mapfupa akakuvara.
• Kuongororwa kwemapfupa emubofu: Izvi zvinosanganisira kutora sampuli diki yemapfupa ako emubofu woiedza kuti uone kana paine masero emubofu asina kujairika mairi, uye kuti mangani.
• Kuongororwa kwemajini: Tarisa kana paine shanduko mujini re'KIT' rataurwa kare.

Inorapwa sei?

Vanachiremba vanorapa Systemic Mastocytosis nekudzora zviratidzo nematambudziko. Semuenzaniso, kana uine acid yakawanda mudumbu, vanogona kunyora H2 blockers (rudzi rwemishonga inorwisa acid). Kana anemia iri mhedzisiro yechirwere, icharapwa. Heano mamwe emishonga mikuru:

• Mishonga inorwisa mabhakitiriya: Inoderedza zviratidzo zveganda zvakaita sekurutsa uye kutsvuka.
• Corticosteroids: Inoderedza kuzvimba uye kuzvimba mumuviri.
• Bisphosphonates: Anobatsira kusimbisa mapfupa kana asina simba.
• Kurapa kwakanangana: Izvi zvinosanganisira kunanga puroteni chaiyo inowanikwa mumasero emasero asina kujairika.
• Kurapa nemakemikari: Izvi zvinongoshandiswa chete kana Systemic Mastocytosis yashanduka kuita kenza.
• Kubviswa kwetsvina: Kana tsandanyama yakazvimba zvakanyanya, inogona kubviswa nekuvhiyiwa.
• Kuisirwa mapfupa emubofu: Izvi zvinoitirwa vanhu vane chirwere chakanyanya, kana kuti vari padanho rekupedzisira.

Yeuka: Kana uine Systemic Mastocytosis, unofanira kugara uine EpiPen . EpiPen mushonga unogona kushandiswa nekukasika kana paine allergy yakanyanya, senge Anaphylaxis yambotaurwa.

"Systemic Mastocytosis" iyi haigone kudzivirirwa here?

Sezvatakambokurukura, "Systemic Mastocytosis" inokonzerwa nekuchinja kwemajini. Saka, hazvigoneke kudzivirira kuti isakure. Zvisinei, unogona kudzora chirwere ichi nekudzivirira "zvinokonzeresa" zvinowedzera zviratidzo.

Munhu ane `(Systemic Mastocytosis)` ane remangwana rerudzii?

Izvi zvinoenderana nekuti une rudzii rwe (Systemic Mastocytosis)`. Vanhu vane rudzi rwe `Indolent systemic mastocytosis` vanongogona kudzora chirwere ichi zvakanaka nekurapwa. Vanogona kurarama hupenyu hwakajairika. Zvisinei, vanhu vane mamwe marudzi akaomarara vanogona kurarama hupenyu hupfupi zvishoma. Zvisinei, `(Systemic Mastocytosis)` inogona kurapwa zvizere nekurapwa kunonzi ``Bone marrow transplant``. Zvisinei, vanachiremba vanongopa kurapa ikoko kuvanhu vari muchikamu chakakomba chechirwere.

Ndingazvitarisira sei ini ndichirarama ne `(Systemic Mastocytosis)`?

Kuziva zvinokonzera zviratidzo zvako uye kuzvidzivisa ndicho chinhu chakakosha chaunogona kuita kana uchirarama neSystemic Mastocytosis. Kana uine chirwere ichi, ziva zvinhu izvi:

• Gara uine EpiPen. Rapa chirwere chinokonzerwa neallergy nekukurumidza.
• Ziva chaizvo kuti chii chinokonzera dambudziko rako uye dzivisa zvese zvaunogona.
• Dzora kushushikana. Dzidzira kufungisisa kana dzimwe nzira dzekufunga.
• Pfeka bracelet yekuzivisa nezvekurapa inoratidza mishonga yausingakwanise kunwa. Izvi zvakakosha nekuti zvinobatsira vanachiremba kuziva mamiriro ako kana usingakwanise kutaura panguva yekukurumidzira.

Ndinofanira kuona chiremba rini?

Kana uine Systemic Mastocytosis, unofanira kuona chiremba wako kuti ugare uchiongororwa. Zvakare, iva nechokwadi chekuudza chiremba wako kana paine zviratidzo zvitsva, kana kana chimwe chezviratidzo zvako chichiratidza kunge chiri kuwedzera kuipa.

Mibvunzo ipi yandinofanira kubvunza chiremba?

Nekuti Systemic Mastocytosis chirwere chisingawanzoitiki, ungave nemibvunzo yakawanda. Heano mimwe mibvunzo yekubvunza chiremba wako:

• Rudzii rwe "Systemic Mastocytosis" rwandinarwo?
• Ndezvipi zvimwe zviratidzo zvingaratidza kuti mamiriro angu ari kuipa?
• Ndeapi marapirwo anowanikwa erudzi rwangu?
• Kurapwa uku kuchabvisa zviratidzo zvangu zvachose here?
• Pane here miedzo yekiriniki yandinogona kutora chikamu mairi?

Kuonekwa uine Systemic Mastocytosis chiitiko chinoshandura hupenyu. Uchafanirwa kuona chiremba wako nguva dzose, kuongororwa ropa, uye kudzidza kuziva uye kudzivirira zvinokonzera. Kurarama nechirwere ichi kuchinja kukuru. Saka, ramba uine hukama hwakanaka nachiremba wako. Varipo kuti vakubatsire. Vachakupa ruzivo nemapoka ekutsigira anogona kukubatsira. Izvi zvichakupa simba rekuita sarudzo nezvehutano hwako.

Pakupedzisira, zvinhu zvekurangarira (Mharidzo Yekuenda Kumba)

Zvakanaka, saka tataura zvakawanda nezve `(Systemic Mastocytosis)`, handiti? Yeuka, kunyangwe ichi chirwere chisingawanzoitiki, zvakakosha kuti uzive nezvacho.

Chinhu chakakosha ndechekuona chiremba kana uine zviratidzo izvi. Kana chirwere chikaonekwa nekukurumidza, kurapwa kunogona kutanga uye zviratidzo zvinogona kudzorwa.

Hausi wega. Vanachiremba vako, mhuri yako, neshamwari dziripo kuti dzikubatsire. Nekuziva ruzivo rwakakodzera uye kutevedzera zano rachiremba wako, unogona kurarama zvakanaka nechirwere ichi. Ramba wakadzikama uye funga zvakanaka!