Siyazi ukuba ukufumana unyango lomhlaza kunokuba ngumsebenzi onzima. Kuqhelekile ukuba nemibuzo efika engqondweni xa ugqirha wakho ekhankanya iyeza elitsha. Namhlanje, siza kuthetha ngelinye lamayeza achasene nomhlaza, i-Aldesleukin. Ngamanye amaxesha ikwabizwa ngokuba yi-IL-2. Makhe sijonge ukuba yintoni eli yeza, yintoni eliyenzayo, kunye nento ekufuneka uyazi ngayo xa ulisebenzisa.
Luhlobo luni lonyango i-Aldesleukin?
Ngamafutshane, i-Aldase liyeza lomhlaza. Kodwa alifani namayeza e-chemotherapy esiwava rhoqo. Enyanisweni liyeza lonyango lokuzikhusela komzimba . Oko kuthetha ukuba endaweni yokubulala ngokuthe ngqo iiseli zomhlaza, livuselela inkqubo yakho yokuzikhusela komzimba kwaye liyinike amandla okulwa neeseli zomhlaza . Kufana nokuqeqesha "amajoni" (iiseli zokuzikhusela komzimba) emizimbeni yethu kwaye liwathumele edabini nxamnye notshaba olubizwa ngokuba ngumhlaza.
Eli yeza (igama lophawu: iProleukin) lisetyenziselwa ikakhulu:
- Kumhlaza weeseli zezintso ongenamandla okanye ophucukileyo .
- Kwi -melanoma ephucukileyo, umhlaza wolusu onzima.
Kwezinye iimeko, oogqirha banokucebisa eli yeza nakwezinye iintlobo zomhlaza.
Izinto ezibalulekileyo omele uzixelele ugqirha wakho ngaphambi kokuba uqale unyango
Ngaphambi kokuba uthathe isigqibo sokuba olu nyango lukulungele na, kubalulekile ukwazisa ugqirha wakho ngembali yakho epheleleyo yempilo. Qiniseka ukuba ubaxelela ngayo nayiphi na kwezi meko zilandelayo, ingakumbi:
- Ukuba uneengxaki zegazi (umz. iingxaki zokujiya kwegazi, i-anemia).
- Ukuba uhlala uziva udiniwe okanye udiniwe .
- Ukuba sele unomkhuhlane okanye enye imeko eyosulelayo emzimbeni.
- Ukuba unesifo sentliziyo, semiphunga, sezintso okanye sesibindi .
- Ukuba unezinye iingxaki zenkqubo yomzimba yokuzikhusela .
- Ukuba unesifo sengqondo (umz. ukudakumba) okanye usela amayeza aso.
- Ukuba ukhe wafakelwa amalungu omzimba ngaphambili.
- Ukuba unesifo sokuxhuzula .
- Ukuba uneengxaki zesisu okanye izifo zenkqubo yokugaya ukutya.
- Ukuba unengxaki ye-thyroid .
- Ukuba une -allergy kwi-aldesleukin okanye naliphi na elinye iyeza, ukutya, okanye idayi .
- Ukuba ukhulelwe, uzama ukukhulelwa, okanye ungumama oncancisayo .
Olu lwazi lubaluleke kakhulu kukhuseleko lwakho, kuba lusekelwe kolu lwazi apho ugqirha aya kugqiba khona ngonyango olufanelekileyo nolukhuselekileyo kuwe.
Uza kunikwa njani eli yeza?
Eli asiloyeza onokulithatha uye nalo ekhaya. I-Aldase inikwa esibhedlele okanye eklinikhi, phantsi kweliso elibukhali loogqirha kunye nabongikazi . Idla ngokunikezelwa njengenaliti emthanjeni (efakwa ngaphakathi kwemithambo yegazi okanye kwi-IV) . Ngamanye amaxesha inokunikwa njengenaliti phantsi kolusu (inaliti engaphantsi kwesikhumba).
Ekubeni olu nyango lunikwa esibhedlele, akufuneki ukhathazeke ngokuphoswa yidosi okanye ukufumana i-overdose. Iqela lezonyango liza kuyinyamekela kakuhle loo nto.
Ukuba ucinga ukuba ngempazamo usele idosi engaphezulu, yazisa ugqirha okanye umongikazi ngokukhawuleza. Nakweyiphi na imeko engxamisekileyo, ungaya kwiCandelo loNyango oluNgxamisekileyo (ETU) lesibhedlele, kwaye xa kukho ingxaki yokutyhefa, ungatsalela umnxeba iZiko loLwazi lweePoisons kwiSibhedlele sikaZwelonke saseColombo .
Lumka ngamanye amayeza owasebenzisayo.
Xa usebenzisa i-aldesleukin, kubalulekile ukuxelela ugqirha wakho ngazo zonke ezinye iziyobisi ozisebenzisayo. Amanye amayeza anokuchaphazela olu nyango. Ngoko ke, kufuneka uwasebenzise:
- Amanye amayeza okulwa nomhlaza (umz. i-doxorubicin, i-methotrexate)
- Ii-antibiotics, ingakumbi ii-aminoglycosides
- Amayeza oxinzelelo lwegazi oluphezulu (umz. ii-beta blockers)
- Amayeza empilo yengqondo (okudakumba, ukuxhalaba)
- Iintlobo zee-steroids (umz. i-prednisone, i-cortisone)
- Iipilisi zokunciphisa iintlungu, ingakumbi ii-NSAID (umz. i-ibuprofen, i-naproxen)
- Iipilisi zokulala
- Amanye amayeza okunciphisa umzimba afana ne-interferon alfa
Ukongeza kolu luhlu, ungalibali ukuxelela ugqirha wakho ngazo naziphi na iivithamini, izongezo zemifuno ozithathayo, kunye nokuba utshaya okanye usela utywala .
Izinto ekufuneka ziqwalaselwe ngokukodwa ngexesha lonyango
- Ukubekwa esweni rhoqo: Uza kubekwa esweni ngononophelo ngoogqirha kunye nabongikazi kulo lonke ixesha lonyango.
- Uvavanyo lwegazi: Kuya kufuneka ukuba uhlolwe igazi rhoqo ukuze ujonge inkqubela yonyango lwakho kwaye ufumane iziphumo ebezingalindelekanga kwangethuba.
- Ukhuseleko kwizifo: Eli yeza linokunciphisa okwethutyana amandla omzimba okulwa nezifo. Ke ngoko,Zama ukuhlala kude nabantu abanomkhuhlane okanye iflu. Ukuba ufumana umkhuhlane okanye usulelo ngelixa usebenzisa amayeza, musa ukuzinyanga kwaye wazise ugqirha wakho ngoko nangoko.
- Ukungakhululeki okuqhelekileyo: Kuqhelekile ukuziva ungakhululekanga okanye ugula ngelixa usebenzisa eli yeza. Le yinxalenye yonyango. Nangona kunjalo, yazisa ugqirha wakho ngazo naziphi na iimpawu okanye iingxaki ezintsha ozifumanisayo.
Zithini iziphumo ebezingalindelekanga ezinokubakho zeyeza?
Njengayo nayiphi na iyeza, i-aldesleukin inokubangela iziphumo ebezingalindelekanga. Ezinye zezi zifuna unyango olukhawulezileyo, ngelixa ezinye zingeyongozi kangako.
| Iziphumo ebezingalindelekanga ekufuneka zixelwe kugqirha/kumongikazi ngoko nangoko | |
|---|---|
| Uphawu | Inkcazo |
| Ukwaliwa kakhulu | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi. |
| Ubunzima bokuphefumla | Ubunzima bokuphefumla, isandi sokuphefumla esiphuma esifubeni. |
| Iingxaki zentliziyo | Iintlungu zesifuba, ukubetha kwentliziyo ngokukhawuleza okanye ngokungangqalanga. |
| Utshintsho lwengqondo | Ukudideka, ukungazinzi, ixhala, ukubona okanye ukuva izinto ezingezizo zokwenyani (imibono). |
| Iingxaki zezintso | Ukuchama okunciphileyo, umchamo otyheli okanye omdaka. |
| Iingxaki zesibindi | Ukutyheli kwamehlo nolusu. |
| Ezinye iimpawu ezinzulu | Ukudinwa kakhulu, ukozela, ukopha okanye ukukrweleka okungaqhelekanga, ukudumba komzimba (ingakumbi ubuso neenyawo), ukudinwa kakhulu, ukuhlanza, umkhuhlane, ukubanda, umqala obuhlungu. |
| Izinto ezingaqhelekanga ukuba zimbi, kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka | |
|---|---|
| Ukudumba (urhudo) | Isicaphucaphu |
| Ukozela | Umnqweno wokutya |
| Izilonda zomlomo | Intlungu yesisu |
Ukuba ufumana naziphi na ezinye iimpawu ezingaqhelekanga ezingakhankanywanga kolu luhlu, nceda wazise ugqirha wakho okanye umongikazi ngazo.
Umyalezo Wokuya Ekhaya
- I-Aldesleukin/IL-2 liyeza elikhethekileyo elinceda ukulwa nomhlaza ngokuvuselela amasosha omzimba wakho, endaweni yokubulala ngokuthe ngqo iiseli zomhlaza.
- Olu nyango lunikwa esibhedlele, phantsi kweliso likagqirha, ngoko ke akufuneki ukhathazeke malunga nomthamo okanye ukugcina iyeza.
- Ngaphambi kokuba uqale unyango, qiniseka ukuba uxelela ugqirha wakho ngazo naziphi na ezinye izifo onazo kunye namayeza owasebenzisayo (kuquka iivithamini kunye namayeza emifuno).
- Ukuba ufumana naziphi na iziphumo ebezingalindelekanga ngexesha lonyango, ezinje ngomkhuhlane, ubunzima bokuphefumla, iintlungu zesifuba, okanye ukudumba okukhulu, yazisa abasebenzi bezonyango ngoko nangoko.
- Olu nyango lunokuba nzima, kodwa awuwedwa. Iqela lakho lezonyango lihlala likulungele ukukunceda. Ungoyiki ukuthetha nabo ngayo nayiphi na imibuzo okanye izinto ezikuxhalabisayo.
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