Isifo sika-Alzheimer sisoyiko abantu abaninzi abanalo engqondweni yabo. Sonke siyazibuza ukuba thina okanye umntu esimthandayo uza kukhula esi sifo na. "Ngaba esi sisifo esizuzwe njengelifa?", "Ngaba kunokwenzeka ukuba nam ndisifumane?" Imibuzo efana nale mhlawumbi isengqondweni yakho. Ngoko ke namhlanje, masithethe ngezizathu zokwenyani zesifo sika-Alzheimer, oko kukuthi, zeziphi izinto ezibangela umngcipheko.
Kwenzeka ntoni engqondweni xa umntu enesifo sika-Alzheimer?
Ngamafutshane, isifo sika-Alzheimer sisifo apho iiseli zobuchopho zifa kancinci kancinci. Izazinzulu zichonge izizathu ezibini eziphambili zoku. Cinga ngengqondo yethu njengesixeko esikhulu, kwaye iiseli zemithambo-luvo ziindlu ezikweso sixeko. Ezi zindlu kufuneka zinxibelelane ukuze isixeko sisebenze kakuhle.
1. Ii-Beta-amyloid plaques: Ezi zifana neengqokelela ezinamathelayo, ezinzima ukuzisusa "zenkunkuma" eziqokelelana kwiindlela zokuhamba phakathi kwezindlu. Kwingqondo ephilileyo, ezi proteni ziyaqhekeka kwaye zisuswe. Kodwa kwisifo sika-Alzheimer, ziyakha kwaye zenze ii-plaques. Oku kuphazamisa unxibelelwano phakathi kweeseli.
2. Iingxaki ze-Neurofibrillary (tau): Cinga ngezi zinto njengento ephazamisa inkqubo yokuhambisa imiyalezo ngaphakathi endlwini yakho. Zenziwa yiproteni ebizwa ngokuba yi-tau. Oku kuyayekisa ukuthuthwa kwezondlo nezinto ezibalulekileyo ngaphakathi kwiiseli zakho.
Ezi plaque kunye ne-tangles ziphazamisa unxibelelwano phakathi kweeseli zobuchopho. Ekuhambeni kwexesha, ezi seli zonakeleyo ziyafa. Ingqondo iqala ukuncipha kancinci kancinci. Oku kubangelwa ziimpawu ezifana nokulibala, ubunzima bokuthetha, ukudideka, kunye notshintsho kwindlela yokuziphatha .
Ngaba esi sisifo esizuzwe njengelifa?
Le yinto abantu abaninzi abayoyikayo. Inyaniso kukuba kukho unxibelelwano oluthile lwemfuza. Ukuba umntu okwintsapho yakho esondeleyo (njengomama, utata, okanye umntakwenu) unesifo se-Alzheimer, unokuba nethuba elincinci lokuba naso. Kodwa oko akuthethi ukuba ngokuqinisekileyo uza kuba naso.
Izazinzulu zifumene ijini ebizwa ngokuba yi-`(Apolipoprotein E - APoE)`. Ukuba une-`(APoE4)` eyahlukileyo yale jini, unamathuba amaninzi okufumana esi sifo kunabanye. Kodwa ayinguye wonke umntu onale jini ofumana esi sifo, kwaye ayinguye wonke umntu ongenale jini oza kufumana esi sifo.
Kunqabile kakhulu ukuba umntu omnye kwabayi-100 abanesifo se-Alzheimer's angakwazi ukuphuhlisa esi sifo ngenxa yotshintsho oluthile lwezakhi zofuzo. Oku kubizwa ngokuba yi-"Early start familial Alzheimer's disease". Singaqala xa umntu ephakathi.
Ngoko ke, ungakhathazeki ukuba kukho umntu kusapho lwakho onesi sifo. Kwiimeko ezininzi, asiyomfuza kuphela ebangela esi sifo. Indlela esiphila ngayo kunye nendawo esihlala kuyo nazo zidlala indima enkulu kuso.
Izinto eziphambili ezibangela umngcipheko wesifo se-Alzheimer's
Isifo sika-Alzheimer asisosifo esibangelwa yimbangela enye. Siyindibaniselwano yezinto ezininzi, kuquka izakhi zofuzo, indlela yokuphila, kunye nendawo esingqongileyo. Makhe sijonge izinto eziphambili ezibangela umngcipheko.
Ukwaluphala
Ukulibala akuyonto iqhelekileyo yokwaluphala. Nangona kunjalo, umngcipheko wokufumana isifo se-Alzheimer uyanda njengoko ukhula. Le ngozi idla ngokuba qatha emva kweminyaka engama-65.
Ukonzakala entloko
Umntu ofumana ukwenzakala kwengqondo emva kweminyaka engama-50 usengozini enkulu yokufumana isifo se-Alzheimer, ingakumbi kwiminyaka emibini yokuqala emva kokwenzakala.
I-Down Syndrome
Abantu abane-Down syndrome basengozini enkulu yokuba nesifo se-Alzheimer kuba i-gene eyenza ii-amyloid plaques, esithethe ngazo ngaphambili, ikwi-chromosome eyongezelelweyo.
| Ingxaki/imeko enxulumene nayo | Ubudlelwane nesifo sika-Alzheimer |
|---|---|
| I-cholesterol ephezulu kunye noxinzelelo lwegazi oluphezulu | Ezi meko zingonakalisa imithambo yegazi ebuthathaka engqondweni. Oku kunciphisa igazi kunye nezondlo ezifikelela engqondweni, nto leyo enokonakalisa iiseli zengqondo. Okulungileyo entliziyweni nako kulungile engqondweni. |
| Isifo seswekile | Abantu abanesifo seswekile basengozini enkulu ye-Alzheimer's. Ngamanye amaxesha, iiseli zobuchopho ziyamelana ne-insulin. Ngenxa yesi sizathu, ezinye izazinzulu zibiza i-Alzheimer's ngokuthi "Type 3 Diabetes." |
| Ukuphelelwa ngamandla kokulala | Ukulala kubalulekile kwimpilo yengqondo. I-sleep apnea inciphisa ubungakanani beoksijini efikelela engqondweni. Ukuba ayinyangwa, inyusa umngcipheko we-Alzheimer's. |
| Ukulahlekelwa Kukuva | Ukulahlekelwa kukuva kunokunciphisa ukusebenza kwezinye iindawo zobuchopho. Kukwanyusa umngcipheko wokuzahlula ngenxa yokulahlekelwa kukuva. Ukusebenzisa izixhobo zokuva kunokunciphisa lo mngcipheko. |
| Ukutshaya kunye nokusetyenziswa kotywala ngokugqithisileyo | Iityhefu ezikwicuba zonakalisa iiseli. Ukusela utywala kakhulu kunokunciphisa iindawo zengqondo ezibandakanyeka kwinkumbulo. Zombini ezi zinto ziyandisa kakhulu umngcipheko we-Alzheimer's. |
| Ukutyeba kakhulu | Ukutyeba kakhulu kunokubangela ukudumba okungapheliyo emzimbeni. Oku kungonakalisa neeseli zobuchopho. Ukutyeba kakhulu kwandisa nezinye izinto ezinobungozi, ezifana nesifo seswekile kunye noxinzelelo lwegazi oluphezulu. |
| Uxinzelelo kunye nokuzahlula ebantwini | Kukho unxibelelwano phakathi koxinzelelo kunye ne-Alzheimer's. Mhlawumbi ezi zinto zimbini zinezizathu ezifanayo. Kwakhona, ukuba wedwa kunye nokuzahlula kwabanye akulunganga kwimpilo yengqondo. |
Kuxoxwe kodwa akukaqinisekiswa iinyaniso
Nangona amarhe esasazeke ngezinto ezithile, akukaqinisekiswa ngokwesayensi ukuba zichaphazela ngqo isifo sika-Alzheimer.
- I-Aluminium: Ngaphambili, kwakukho inkolelo yokuba ukusebenzisa izixhobo ze-aluminium kubangela i-Alzheimer's. Nangona kunjalo, izifundo ezininzi ngoku zibonisa ukuba ubungakanani be-aluminium esetyenziswa ngobuninzi obuqhelekileyo abunabungozi.
- Iintsholongwane: Kuqhutywa uphando ukuze kufunyaniswe ukuba kukho unxibelelwano phakathi kweentlobo ezithile zeentsholongwane (umz., intsholongwane ye-herpes) kunye ne-Alzheimer's, kodwa akukho sigqibo siqinisekileyo esifikelelweyo.
Izinto esinokuzenza ukunciphisa umngcipheko
Nangona kungekho ndlela yokuthintela isifo se-Alzheimer ngokupheleleyo, zininzi izinto esinokuzenza ukunciphisa umngcipheko.
1. Zivocavoce rhoqo: Xa uzivocavoca, ingqondo yakho ifumana ukuhamba kwegazi okungcono kunye neoksijini engcono. Oku kuphucula impilo yengqondo.
2. Yitya ukutya okunempilo kwentliziyo: Nciphisa ukutya okuneoyile eninzi, amafutha, kunye neswekile, kwaye utye imifuno, iziqhamo kunye nemifuno eluhlaza ngakumbi. Okulungileyo kwintliziyo nako kulungile engqondweni.
3. Lala ngokwaneleyo: Kubalulekile ukulala iiyure ezi-6-8 ngosuku. Kuxa ulele apho ingqondo izicoca khona.
4. Cela umngeni engqondweni yakho: Funda into entsha, funda iincwadi, sombulula iiphazili, yiba nobudlelwane nabantu. Ukugcina ingqondo yakho isebenza kubaluleke kakhulu.
5. Lawula ezinye izifo: Ukuba unezifo ezifana nesifo seswekile, uxinzelelo lwegazi oluphezulu, okanye i-cholesterol, landela imiyalelo kagqirha wakho ngononophelo . Ukuzilawula kakuhle kunokunceda ekunciphiseni umngcipheko wakho we-Alzheimer's.
Umyalezo Wokuya Ekhaya
- Isifo sika-Alzheimer asibangelwa yimbangela enye. Siyindibaniselwano yezinto ezininzi, kuquka ii-genes, indlela yokuphila kunye neemeko zempilo.
- Ukuba umntu kusapho lwakho ukhe waba nesi sifo akuthethi ukuba uza kuba naso. Indlela esiphila ngayo inokuba nefuthe elikhulu kunezakhi zofuzo.
- Kukho unxibelelwano oluqinileyo phakathi kwempilo yentliziyo nempilo yengqondo. Ukwenza izinto ezilungileyo entliziyweni kukwakhusela ingqondo.
- Ukuba uneenkxalabo okanye amathandabuzo ngale nto, thetha nogqirha wakho ngayo ngokukhululekileyo . Yena angakunika icebiso elifanelekileyo.
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