Xa sisiva igama elithi umhlaza, sonke siyoyika kancinci. Kwangaxeshanye, sisoloko sifuna unyango olutsha kunye nethemba elitsha lesi sifo. Ngamanye amaxesha, sinokufumana ithemba elinjalo nakwisityalo esincinci. Namhlanje siza kuthetha ngento efana naleyo. Usenokuba ukhe weva nge-'Sweet Wormwood'. Ookhokho bethu, ingakumbi eTshayina, babesebenzisa iti eyenziwe ngesi sityalo kwimfiva kunye nemalariya. Esi sityalo (igama lesayensi elithi `Artemisia annua`) siqulethe i-compound ekhethekileyo. Yiyo leyo esiyibiza ngokuba yi-Artemisinin . Kwananamhlanje, iyeza elithi `(Artesunate)` elicetyiswa ngoogqirha kwimalariya lenziwa ngokusekelwe kule compound.
Ingxoxo yamva nje kukuba ingaba le artemisinin inokuba lolunye unyango lomhlaza. Kuba ezinye iiseli zomhlaza ziyachasana nonyango lomhlaza oluqhelekileyo ('i-chemotherapy') ngokuhamba kwexesha. Kodwa i-artemisinin ayibonakali ichasana nayo. Esinye isizathu kukuba, ngokungafaniyo namayeza amaninzi omhlaza, ayinabungozi emzimbeni. Kwakhona, ingabizi kwaye inokusetyenziswa ngokulula. Ngoko ke, yintoni inyaniso kweli bali? Masibone.
Oku kwenza ntoni ngokwenene kwiiseli zomhlaza?
Kulula kakhulu ukuyiqonda le nto. Cinga ngeeseli zomhlaza njengotshaba oludla isinyithi. Iiseli zomhlaza zifuna isinyithi esininzi ukuze zikhule kwaye zisasazeke. Okungaphezulu kakhulu kuneeseli zethu eziphilileyo.
Kulapho iqhawe i-artemisinin lingena khona. Xa i-artemisinin kunye ne-iron zidityaniswe ngaphakathi kwiseli yomhlaza, kwenzeka i-chemical reaction phakathi kwezi zimbini. Oku kudala amasuntswana asabela kakhulu esiwabiza ngokuba zii-free radicals . La masuntswana afana neebhombu. Kodwa la masuntswana aqhuma kuphela ngaphakathi kwiseli yomhlaza. Oku kuthetha ukuba le nkqubo itshabalalisa iiseli zomhlaza, kodwa iiseli zethu eziphilileyo azonzakali. Oku koko abaphandi abakubona njengeyona nzuzo inkulu nebaluleke kakhulu yale ndlela yonyango.
Uphando lubonise ukuba i-artemisinin inokwenza ezinye izinto ezininzi kwiiseli zomhlaza.
- Kunyanzela iiseli zomhlaza ukuba zizibulale: Ngamanye amaxesha oku kunika imiqondiso yokuba iiseli zomhlaza zizitshabalalise.
- Iyayeka ukwahlukana nokusasazeka: Oku kunokuthintela iiseli zomhlaza ukuba zingahlukani kwaye zisasazeke ngokukhawuleza.
- Inciphisa ukunikezelwa kwegazi: Ithumba lifuna imithambo yegazi ukuze likhule. Eli yeza linokunqumla ukunikezelwa kwegazi. Emva koko umhlaza ulahlekelwa zizondlo ozifunayo.
Ingaba oku kuyaphumelela ngenene? Yintoni uphando?
Le yeyona nto ibalulekileyo sonke ekufuneka siyazi. Zimbalwa kakhulu izifundo ezenziweyo ngale nto. Kwaye kuzo zonke ezi zifundo, i-artemisinin isetyenziswe kunye nonyango oluqhelekileyo lomhlaza.Ayikaze isetyenziswe njengendlela yonyango lomhlaza, ngoko ke kufuneka kwenziwe uphando oluninzi ukuqinisekisa ukuba isebenza kangakanani na.
Nangona kunjalo, ezinye iingcali zinethemba emva kokujonga iziphumo zezi zifundo zincinci. Makhe sibone ukuba ezi zifundo zimbalwa zifumene ntoni.
| Uhlobo lomhlaza | Iziphumo zoPhando |
|---|---|
| Umhlaza weColorectal | Kuphononongo lwezigulane ezingama-20, kufunyaniswe ukuba iiseli zomhlaza kwabo banikwe uhlobo lwe-artemisinin olubizwa ngokuba yi-artesunate bafe nge-12% ngaphezulu kunezo zabo bangazange bathathe iyeza. |
| I-Melanoma | I-Artesunate ibonakalise iziphumo ezilungileyo xa inikwa kunye namanye amayeza kwizigulane ezine-melanoma eqhubele phambili, umhlaza wolusu ochaphazela iliso. Esinye isigulana saphila iinyanga ezingama-47 emva kokuba sifunyenwe sinomhlaza. Ixesha eliqhelekileyo lokusinda kule meko ziinyanga ezi-2-5. |
| Umhlaza wemiphunga | Kuphononongo olubandakanya izigulana ezili-120 ezinomhlaza wemiphunga ongengoweeseli ezincinci oqhubele phambili, kwaphawulwa ukuba izinga lokusasazeka komhlaza kwabo bafumana i-artesunate kunye ne-chemotherapy eqhelekileyo liphantsi kunabo bangazange bafumane. |
| Umhlaza woMlomo | Abafazi abalishumi abanomhlaza womlomo wesibeleko oqhubele phambili banikwa i-artemisinin kangangeentsuku ezingama-28. Bonke abali-10 baxele ukuba iimpawu zabo (iintlungu, ukukhupha ulwelo kwilungu lobufazi) ziphelile kwaye isifo siphelile. |
Nangona ezi ziphumo zithembisa, khumbula ukuba zisesekwinqanaba lophando. Azibonakali ukuba ziyindlela yonyango esisigxina.
Ngaba akukho zingozi kunye nemiphumo emibi?
Njengalo naliphi na iyeza, eli linokuba nemiphumo emibi. Nangona kunjalo, uphando ngalo mba alukho. Nazi ezo zixeliweyo ukuza kuthi ga ngoku:
- Ukuqhambuka kwesikhumba
- Ukulahlekelwa kukuva
- Ukukhala ezindlebeni
- Isiyezi
Asisazi nto ingako ngale nto. Kusekho okuninzi okusamele kufunyanwe. Ngoko ke ukuba ucinga ngolu hlobo lonyango olulolunye, ngokuqinisekileyo kuya kufuneka uthethe nogqirha wakho okanye iqela lezonyango ngalo. Ungaze wenze izigqibo wedwa. Banokukunika iingcebiso malunga nokuba lufanelekile kangakanani na kwimeko yakho, okanye ukuba ungajoyina na uvavanyo lweklinikhi kwenye indawo ehlabathini.
Umyalezo Wokuya Ekhaya
- I-Artemisinin yikhemikhali ekhutshwa kwisityalo kwaye isetyenziselwa ukunyanga i-malaria.
- Uphando lokuqala lubonise ukuba kukho amandla okubulala iiseli zomhlaza, kodwa olu ayilonyango lomhlaza oluqinisekisiweyo okwangoku.
- Kukholelwa ukuba isabela kunye nesinyithi kwiiseli zomhlaza kwaye ibulale iiseli zomhlaza ngaphandle kokulimaza iiseli eziphilileyo.
- Musa ukuyeka unyango lomhlaza olucetyiswa ngugqirha nangasiphi na isizathu kwaye sebenzisa ezinye iindlela zonyango ezifana nezi.
- Ukuba unomdla koku, qiniseka ukuba uxoxa ngako nogqirha wakho kwaye ucele icebiso lakhe.
💬 Comments (0)
Akukho zimvo zithunyelweyo okwangoku. Faka uluvo lwakho apha okokuqala.
Faka uluvo lwakho