Isitofu sokugonya seBendamustine: Ukukhuthaza ukulwa kwakho nomhlaza!

Xa ugqirha ekuxelela okanye umntu omaziyo ukuba unomhlaza, kunokuba ngumthwalo omkhulu, akunjalo? Ngelo xesha, sinemibuzo emininzi malunga namayeza anikwayo, indlela asebenza ngayo, kunye nento ekufuneka uyilumkele. I-Bendamustine liyeza elibalulekileyo elisetyenziselwa ukunyanga ezinye iintlobo zomhlaza. Eli liyeza le-chemotherapy elinceda ekutshabalaliseni iiseli zomhlaza. Namhlanje, masithethe ngeenkcukacha zale chiza le-Bendamustine ngendlela elula, kulungile?

Lithini eli yeza libizwa ngokuba yiBendamustine?

Ngamafutshane, iBendamustine liyeza elithintela ukukhula kweeseli zomhlaza kwaye lizibulale. Isetyenziswa kakhulu ukunyanga uhlobo lomhlaza wegazi olubizwa ngokuba yiChronic Lymphocytic Leukemia (CLL) kunye nohlobo lomhlaza olubizwa ngokuba yiNon-Hodgkin Lymphoma (NHL) .

Nangona kunjalo, ngamanye amaxesha oogqirha banokusebenzisa eli yeza kwezinye iintlobo zomhlaza. Ukuba unemibuzo malunga noku, kungcono ukubuza ugqirha wakho okanye ingcali yezonyango.

Eli yeza lingafumaneka kwimarike phantsi kwamagama anje ngo `BELRAPZO`, `BENDEKA`, kunye no `Treanda`.

Ndimele ndimxelele ntoni ugqirha ngaphambi kokuba ndithathe eli yeza?

Eli linqaku elibaluleke kakhulu. Ngaphambi kokuba uqale ukusebenzisa eli yeza, kubalulekile ukuxelela ugqirha wakho okanye iqela lezonyango elikunyangayo:

• Ngaba okwangoku unesifo? Ingakumbi isifo sentsholongwane esifana ne-chickenpox, i-herpes, okanye into efana nomkhuhlane okanye umkhuhlane.
• Ingaba unesifo sezintso?
• Ingaba unayo nayiphi na isifo sesibindi?
• Ngaba wakha waba ne-allergy kweli yeza, into eyi-mannitol ekulo, kwamanye amayeza, ekutyeni, kwiidayi kwezinye ukutya, okanye kwizigcini? Ukuba ukhe waba ne-allergy engaqhelekanga okanye ngaphambili, nceda usixelele ngazo.
• Ngaba ukhulelwe okwangoku okanye ulindele umntwana kungekudala?
• Ingaba ungumama oncancisayo?

Kubaluleke kakhulu ukuxelela ugqirha wakho olu lwazi, kuba kulapho kuphela apho unokunyangelwa khona ngokukhuselekileyo nangokuchanekileyo.

Ulisebenzisa njani eli yeza?

I-Bendamustine ayilo pilisi onokuyisela ekhaya. Inikwa njenge-infusion emthanjeni. Oko kukuthi, njenge-saline, iyeza lingena kancinci emzimbeni.

Olu nyango lwenziwa ngugqirha okanye umongikazi oqeqeshiweyo esibhedlele okanye kwikliniki yomhlaza.Ngu.

• Ukuba unika abantwana abancinci eli yeza, ngokuqinisekileyo kuya kufuneka uthethe nogqirha wakho wabantwana ngalo. Basenokufuna unyango olukhethekileyo.
• Kuthekani ukuba ndithatha eli yeza kakhulu ngempazamo? Ukuba oku kuyenzeka, qhagamshelana ngokukhawuleza neziko lolawulo lwetyhefu okanye igumbi likaxakeka elikufutshane.
• Oku kubaluleke kakhulu: Eli yeza lelakho kuphela. Musa ukwabelana ngeli yeza nabanye abantu nangasiphi na isizathu .

Ndenze ntoni ukuba ndiphoswe yidosi?

Akuyonto ilungileyo ukuphosa idosi yale yeza. Oku kunokuchaphazela impumelelo yonyango. Ukuba uphosa idosi ngosuku olucwangcisiweyo, fowunela ugqirha wakho okanye ingcali yezempilo ngokukhawuleza. Baza kukuxelela into omawuyenze ngokulandelayo.

Ngawaphi amanye amayeza anokusebenza kunye nale mithi?

Le yingongoma ebaluleke kakhulu. I-Bendamustine inokusebenzisana namanye amayeza owasebenzisayo. Oko kukuthi, elinye iyeza linokuchaphazela ukusebenza kwelinye iyeza.

• Musa ukuthatha iBendamustine kunye namayeza alandelayo:
• I-Clozapine

• Kwakhona, la mayeza alandelayo anokusebenzisana neBendamustine. Ngoko ke, kufuneka uxelele ugqirha wakho ukuba usebenzisa la mayeza:
• I-Atazanavir
• I-Cimetidine
• I-Ciprofloxacin
• I-Enoxacin
• I-Fluvoxamine
• Amayeza anikwayo xa umntu enesithukuthezi, umzekelo, iCarbamazepine kunye nePhenobarbital
• I-Mexiletine `(Mexiletine)`
• I-Rifampin
• I-Tacrine
• I-Thiabendazole
• I-Zileuton

Olu luhlu aluphelelanga. Ngoko ke, xelela ugqirha wakho ngawo onke amayeza owasebenzisayo (kuquka lawo achazwe ngugqirha wakho, amayeza athengiswa ngaphandle kwemvume kagqirha, amayeza esintu, iivithamini, imifuno, izongezo zokutya). Kwakhona, xelela ugqirha wakho ukuba uyatshaya, usela utywala, okanye usebenzisa ezinye iziyobisi ezingekho mthethweni. Ezinye zezi zinto zinokudibana namayeza akho.

Yintoni endifanele ndiyiqaphele xa ndisebenzisa eli yeza?

Ngenxa yokuba iBendamustine liyeza elinamandla, kufuneka ulumke ngakumbi ngezinye izinto xa uyisebenzisa.

• Ndiziva ndicaphukile:Ungaziva ukhathazekile kwaye udiniwe ngelixa usebenzisa eli yeza. Oku kuqhelekile. Oku kungenxa yokuba i-chemotherapy ayichaphazeli kuphela iiseli zomhlaza kodwa neeseli ezisempilweni emzimbeni wethu. Xelela ugqirha wakho ngazo naziphi na iziphumo ebezingalindelekanga ozifumanayo. Qhubeka nonyango nokuba alukukhululeki, de ugqirha wakho akuxelele ukuba uyeke.
• Uvavanyo lwegazi: Ugqirha wakho uhlala eyalela uvavanyo lwegazi (umsebenzi wegazi) ukujonga inani legazi lakho ngelixa usela eli yeza.
• Ukuzikhusela kwiintsholongwane: Ukuba uneempawu ezinje ngomkhuhlane, ukubanda, umphimbo obuhlungu, ukukhwehlela, okanye impumlo egobhozayo, xelela ugqirha wakho okanye umboneleli wezempilo ngoko nangoko. Musa ukuzinyanga. Eli yeza linokunciphisa amandla omzimba wakho okulwa nokugula (amasosha omzimba). Ngoko ke, zama ukuhlala kude nabantu abagulayo kangangoko unako.
• Iimpendulo ezinzulu zesikhumba: Eli yeza linokubangela iimpendulo ezinzulu zesikhumba kwabanye abantu. Ezi zinokwenzeka kwiiveki okanye kwiinyanga emva kokuba uqalise iyeza. Xelela ugqirha wakho ngoko nangoko ukuba ufumana irhashalala yesikhumba kunye nomkhuhlane okanye iimpawu ezifana nomkhuhlane. Irhashalala inokuba bomvu okanye mfusa ize emva koko ibe namaqhubu kwaye ixobuke. Okanye unokufumana irhashalala ebomvu enokuvuvukala kobuso, imilebe, okanye ii-lymph nodes ezivuvukileyo entanyeni okanye emakhwapheni. Ukuba ubona into efana nale, xelela ugqirha wakho ngoko nangoko.
• Ukosuleleka ebuchotsheni: Nangona kunqabile, abanye abantu baye banesifo sosulelo ebuchotsheni ngenxa yale yeza, esinokuba yingozi. Ukuba ubona naluphi na utshintsho okanye ubunzima bokubona, ukucinga, ukuthetha, ukuhamba, okanye ukuma, xelela ugqirha wakho ngoko nangoko. Ukuba awukwazi ukufikelela kugqirha wakho, funa ingcebiso yezonyango ngoko nangoko.
• Ukopha nokukrwela: Eli yeza linokukwenza ube namathuba amaninzi okukrwela okanye ukopha ngokulula. Xelela ugqirha wakho ukuba ubona ukopha okungaqhelekanga (umz., ukopha iintsini xa uhlamba amazinyo akho, ukopha impumlo, okanye ukukrwela eluswini lwakho).
• Umngcipheko weminye imihlaza: Kunokubakho umngcipheko omncinci, ongaqhelekanga wokufumana iintlobo ezithile zomhlaza ngelixa usebenzisa eli yeza. Thetha nogqirha wakho ngale nto.
• Umngcipheko womhlaza wolusu: Eli yeza linokukwandisa umngcipheko wakho womhlaza wolusu. Ngoko ke, ngelixa usela eli yeza, jonga ulusu lwakho rhoqo ukuba akukho naluphi na utshintsho eluswini lwakho, olufana neenduli ezintsha okanye ukukhula. Ukuba ubona naluphi na utshintsho, xelela ugqirha wakho .
• Ukukhulelwa nokuzala:
• Abafazi:Musa ukukhulelwa ngelixa usela eli yeza, kwaye ubuncinane iinyanga ezi-6 emva kokuyeka iyeza. Ukuba uzama ukukhulelwa, okanye ukuba ucinga ukuba ukhulelwe, xelela ugqirha wakho ngoko nangoko.
• Amadoda: Musa ukuzama ukuba nguyise womntwana ngelixa usela eli yeza, okanye ubuncinane iinyanga ezi-3 emva kokuba uyekile ukulisebenzisa. Eli yeza linokubangela iziphumo ebezingalindelekanga ezibi kakhulu kusana olungekazalwa. Buza ugqirha wakho okanye ikhemisti ukuze ufumane ulwazi oluthe kratya.
• Oomama abancancisayo: Musa ukuncancisa umntwana wakho ngelixa usebenzisa eli yeza, kwaye ubuncinane iveki emva kokuba uyekile ukusebenzisa eli yeza.
• Ukuzala: Eli yeza lisenokuchaphazela amandla akho okuba nguyise wabantwana (ukuncipha kokuzala, okwenza kube nzima ukuba nguyise womntwana / uxhalabele ukuzala) . Ukuba unemibuzo malunga noku, thetha nogqirha wakho.

Zeziphi iziphumo ebezingalindelekanga endinokuzifumana kweli yeza?

Njengayo nayiphi na imithi, i-bendamustine inokubangela ezinye iziphumo ebezingalindelekanga. Ezinye zazo kufuneka zixelwe kugqirha wakho ngoko nangoko, ngelixa ezinye kufuneka zijongwe okwethutyana kwaye ukuba ziyaqhubeka okanye ziyakhathaza, kufuneka uxelele ugqirha wakho .

Iziphumo ebezingalindelekanga ekufuneka zixelwe kugqirha ngoko nangoko:

• Iimpendulo ze-allergy: Ukurhawuzelela kwesikhumba, ukurhawuzelela, amaqhuqhuva, ukudumba kobuso, imilebe nolwimi.
• Ukubalwa kwegazi okuphantsi: Eli yeza linokubangela ukwehla kwenani leeseli ezimhlophe zegazi, iiseli ezibomvu zegazi, kunye neeplatelets. Oku kunokukwenza ube namathuba amaninzi okufumana usulelo kwaye kunokubangela ukopha.
• Urhawuzelelo, umkhuhlane, kunye nokudumba kwama-lymph nodes.
• Ulusu olubomvu, olunamadyungudyungu, noluxobukayo (kuquka nomlomo).
• Iimpawu zosulelo: umkhuhlane okanye ukubanda, ukukhohlela, umphimbo obuhlungu, iintlungu okanye ubunzima bokuchama.
• Iimpawu zeeplatelets ezisezantsi okanye ukopha: ukukrweleka, amachaphaza amancinci abomvu eluswini (i-petechiae), indle emnyama ethambileyo, kunye negazi kumchamo.
• Iimpawu zeeseli ezibomvu zegazi ezisezantsi: ukudinwa okanye ubuthathaka obukhulu, ukuquleka, kunye nokuziva unesizungu.
• Iimpawu zokulimala kwezintso: Ubunzima bokuchama okanye utshintsho kubungakanani bomchamo owuvelisayo.
• Iimpawu kunye neempawu zokulimala kwesibindi: Umchamo otyheli okanye omdaka omnyama; ukuziva ungaphilanga okanye unomkhuhlane; indle ekhanyayo; ukungabi namdla wokutya; isicaphucaphu; iintlungu kwicala eliphezulu lasekunene lesisu; ukuziva udiniwe kakhulu okanye ungonwabanga; ukutyheli kwamehlo okanye ulusu.

Ngokwesiqhelo ayifuni unyango (kodwa ukuba iyaqhubeka okanye iyakhathaza, bona ugqirha).Kufuneka nditsho) Iziphumo ebezingalindelekanga:

• Ukuqhinwa
• Ukunciphisa ukutya
• Urhudo (ukudumba kwesisu)
• Intloko ebuhlungu
• Izilonda zomlomo
• Isicaphucaphu, ukuhlanza
• Ukudinwa

Olu luhlu alubandakanyi zonke iziphumo ebezingalindelekanga. Ukuba ubona nantoni na engaqhelekanga ukongeza kwezi, thetha nogqirha wakho ngayo.

Ndingaligcina phi eli yeza?

Ekubeni le naliti yeBendamustine inikwa wena esibhedlele okanye ekliniki, akufuneki uyithathe uye nayo ekhaya. Ngoko ke akukho nto ibalulekileyo.

Ezona zinto zibalulekileyo ekufuneka sizikhumbule kweli bali zezi:

Kulungile, nazi izinto ezibalulekileyo ekufuneka uzikhumbule koko sithethe ngako:

• I-Bendamustine liyeza elinamandla le-chemotherapy elinceda ekulweni neeseli zomhlaza.
• Ngaphambi kokuba uqalise eli yeza, kubaluleke kakhulu ukuxelela ugqirha wakho ngalo lonke ulwazi lwakho lwempilo kunye nawo onke amayeza owasebenzisayo.
• Ezinye iziphumo ebezingalindelekanga zinokwenzeka xa usebenzisa eli yeza. Ngoko ke, kubalulekile ukuba uzazi kwaye uxelele ugqirha wakho ukuba ufumana naziphi na iingxaki.
• Ingakumbi ukuba uqaphela into efana nomkhuhlane, utshintsho olukhulu lolusu, okanye ukopha okungaqhelekanga, yazisa ugqirha wakho ngoko nangoko.
• Ukuba ukhulelwe, uzama ukukhulelwa, okanye ukuncancisa, kufuneka uthethe ngqo nogqirha wakho malunga nokusela la mayeza.
• Khumbula, ukuba unemibuzo okanye izinto ezikuxhalabisayo, ungoyiki ukubuza ugqirha wakho, umongikazi, okanye ingcali yezemithi. Bakho ukuze bakuncede.

Ndiyathemba ukuba olu lwazi luza kukunceda. Ndikunqwenelela ukuchacha ngokukhawuleza!

i- bendamustine, i-chemotherapy, umhlaza, i-leukemia, i-lymphoma, iziphumo ebezingalindelekanga, amayeza omhlaza