Xa wena okanye umntu omthandayo ninikwa amayeza athi `Daratumumab` kunye ne `Hyaluronidase` njengonyango lomhlaza, nisenokuziva nisoyika kancinci ngamagama lawo. Kuqhelekile ukuba nemibuzo emininzi efana nokuba loluphi uhlobo lonyango, kuza kwenzeka ntoni emzimbeni, kwaye ngaba kukho naziphi na iziphumo ebezingalindelekanga. Ngoko ke namhlanje, masithethe ngale mayeza, ngokungathi umhlobo wakho, ugqirha, ebekuchazela ezi zinto ngendlela elula.
Yintoni iDaratumumab kunye neHyaluronidase?
Ngamafutshane, olu lunyango oluthile olubulala iiseli zomhlaza. Apha, iintlobo ezimbini zamayeza zisebenza kunye. Masiziqonde ngokwahlukeneyo.
- I-Daratumumab: Eli liyeza elikrelekrele kakhulu. Ngokwesayensi, liyi-`(i-Monoclonal Antibody)`. Khawuthelekelele, ngaba imikhosi yethu ayinazo imikhosi ekhethekileyo ekwaziyo ukuchonga iintshaba nokuzihlasela zodwa? Ngokufanayo, eli yeza libizwa ngokuba yi-`Daratumumab` lichonga iproteni ethile kumphezulu weeseli zomhlaza emzimbeni wethu, linamathela kwezo seli kuphela, kwaye linceda ekuzitshabalaliseni. Ngenxa yoku, umonakalo kwiiseli ezisempilweni uncinci kakhulu. Olu lunyango olukhethekileyo.
- I-Hyaluronidase: Le "ngumncedisi" weyeza eliphambili. Iyeza elithi `Daratumumab` linikwa njengenaliti phantsi kolusu. Ngoko ke, eli yeza elithi `Hyaluronidase` linceda ukuba iyeza lifunxwe kwiithishu eziphantsi kolusu. Lenza umsebenzi ofana nokukhulula umhlaba kancinci ngaphambi kokuba uwunkcenkceshele. Oku kuvumela iyeza eliphambili ukuba lingene emzimbeni ngokufanelekileyo.
Olu nyango lusetyenziswa kakhulu kwiimeko zomhlaza ezifana ne-"Multiple Myeloma" kunye ne-"Light-chain Amyloidosis".
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale unyango
Kubaluleke kakhulu ukuba ugqirha wakho ayazi imbali yakho epheleleyo yempilo ukuze agqibe ukuba olu nyango lukulungele na kwaye alwenze njani ngokukhuselekileyo. Ngoko ke, qiniseka ukuba uxelela ugqirha wakho ukuba unayo nayiphi na kwezi zilandelayo:
- Isifo sentliziyo: Ukuba unesifo sentliziyo, eli yeza lingayichaphazela intliziyo yakho.
- Iintsholongwane ezikhoyo: Ukuba unezifo emzimbeni wakho, ingakumbi izifo ezibangelwa ziintsholongwane ezifana ne-chickenpox, i-herpes, okanye i-hepatitis B, ezi zifo zinokuphinda zivele kuba eli yeza lithintela amajoni akho omzimba.
- Izifo zemiphunga okanye zokuphefumla: Kubalulekile ukuxela naziphi na iingxaki zokuphefumla ezifana ne-asthma.
- Ukuba uzama ukukhulelwa okanye ukhulelwe: Oku kubaluleke kakhulu. Kufuneka uphephe ukukhulelwa ngelixa usebenzisa eli yeza kwaye emva kweenyanga ezi-3 uyekile unyango. Oku kunokubangela ingozi enkulu kusana olungekazalwa.
- Ukuba ungumama oncancisayo: Akucetyiswa ukuba uncancise umntwana wakho ngelixa usebenzisa eli yeza.
- Ukunganyamezelani kwamanye amayeza okanye ukutya: Ukuba ukhe waba ne-allergy nakweyiphi na iyeza ngaphambili, sixelele ngayo.
Kukhuselekile kuwe ukuthetha nogqirha ngaphandle kokufihla olu lwazi.
Linikwa njani eli yeza?
Eli asiloyeza onokulithatha ekhaya. Lifakwa phantsi kolusu lwakho (ngaphantsi kwesikhumba) yingcali yezonyango eqeqeshiweyo esibhedlele okanye eklinikhi. Ngoko ke akufuneki ukhathazeke ngomthamo okanye indlela elinikwa ngayo.
Nangona kunjalo, kubaluleke kakhulu ukuza kunyango kanye ngemihla namaxesha anikwe ngugqirha. Kubaluleke kakhulu ukugcina umjikelo wonyango ngaphandle kokuwuphazamisa ngexesha lonyango lomhlaza. Ukuba awukwazi ukuza ngosuku olucwangcisiweyo, fowunela ugqirha wakho ngoko nangoko umxelele.
Kuthekani ukuba ndithatha amayeza amaninzi kakhulu?
Oku kubonelelwa esibhedlele, ngoko ke amathuba okuba oku kwenzeke aphantsi kakhulu. Nangona kunjalo, ukuba ukrokrela ukuba kukho into eyenzekileyo, yazisa abasebenzi ngoko nangoko. Ukuba unenkxalabo malunga naliphi na iyeza, ungafowunela iZiko loLwazi lweeTyhefu leSizwe kwiSibhedlele sikaZwelonke saseColombo . Kwimeko yengxamiseko, kubalulekile ukuya kwiYunithi yoNyango oluNgxamisekileyo (ETU) ekufutshane.
Izinto ekufuneka ziqwalaselwe ngakumbi ngexesha lonyango
1. Ukufanisana kweGazi
Le yeyona nto ibalulekileyo nekhethekileyo ekufuneka uyazi ngale yeza. Eli yeza libizwa ngokuba yi-'Daratumumab' linokuchaphazela iziphumo zezinye iimvavanyo ezijonga uhlobo lwegazi lakho. Khawuthelekelele, uhlobo lwegazi lakho yi-B+. Uvavanyo olwenziwe ngelixa usela eli yeza lunokubonisa ngokwahlukileyo. Le meko inokuhlala malunga neenyanga ezi-6 emva komthamo wokugqibela weyeza.
Ngoko ke yintoni intsingiselo yoku? Ukuba udinga utofelo-gazi, oku kungaba ngumqobo ekufumaneni umntu ofanelekileyo ofanelana naye.
Ngoko ke:
- Ugqirha wakho uza kujonga uhlobo lwegazi lakho kunye nokuhambelana kwalo aze agcine iirekhodi ngaphambi kokuba aqalise olu nyango.
- Ufanele wazise ugqirha okanye isibhedlele ukuba usela eli yeza, kwaye emva kweenyanga ezi-6 ulisela, ingakumbi ngaphambi kokuba unikele ngegazi.
2. Iimpendulo ze-Allergic
Abanye abantu banokuba ne-allergy enkulu kweli yeza. Ukunciphisa lo mngcipheko, ugqirha wakho unokukunika amanye amayeza (afana nePiriton) ngaphambi kokuba akunike eli gonyo. Ngoko ke landela imiyalelo ngokuchanekileyo.
Zithini iziphumo ebezingalindelekanga ezinokubakho zale yeza?
Njengayo nayiphi na iyeza, eli linokuba nemiphumo emibi. Kodwa ayinguye wonke umntu oyifumanayo. Ezinye ziyingozi, ezinye ziqhelekile. Eyona nto ibalulekileyo kukwazi ezi zinto kwaye wazise ugqirha wakho ngoko nangoko ukuba ubona into eyingozi.
| Iziphumo ebezingalindelekanga ekufuneka zixelwe kwiqela lakho lezonyango ngoko nangoko | |
|---|---|
| Imiphumela | Inkcazo |
| Ukwaliwa kakhulu | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi. |
| Ukugabha kwegazi | Intlungu esifubeni, ubunzima bokuphefumla, intlungu, ukudumba, okanye ukufudumala emlenzeni. |
| Iimpendulo kwigonyo | Ukudinwa, ukubetha kwentliziyo ngokukhawuleza, ukuquleka, intloko ebuhlungu, uxinzelelo lwegazi oluphezulu, isicaphucaphu, ukuhlanza, ukuphefumla. |
| Iimpawu zosulelo | Umkhuhlane, ukubanda, ukukhohlela, umphimbo obuhlungu. |
| Ukuncipha kweeseli ezibomvu zegazi | Ubunzima bokuphefumla, ukuquleka, ukudinwa kakhulu, ukuphaphatheka. |
| Ezinye iimpawu ezinzulu | Umbono ofipheleyo, ukubetha kwentliziyo okungaqhelekanga, ukopha okungaqhelekanga okanye ukukrweleka. |
| Iziphumo ebezingalindelekanga ezingaqhelekanga (kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka) | |
|---|---|
| Umqolo obuhlungu | Ukuqhinwa okanye urhudo |
| Ukungaziva mnandi okanye iintlungu ezinyaweni | Ububomvu kunye nobuhlungu kwindawo yokujova |
| Intlungu yemisipha | Ukudumba kwamaqatha, iinyawo, izandla |
| Ukudinwa kakhulu | Ukungalali |
Umyalezo Wokuya Ekhaya
- I-'Daratumumab' 'lunyango olujoliswe kulo' oluhlasela iiseli zomhlaza. I-'Hyaluronidase'' liyeza elincedisayo elinceda ngaloo nto.
- Ngaphambi kokuba uqale unyango, xelela ugqirha wakho ngazo zonke iimeko zakho zempilo kunye namayeza owasebenzisayo. Musa ukufihla nantoni na.
- Okubaluleke kakhulu: Ukuba kuya kufuneka unikele ngegazi, xelela ugqirha okanye isibhedlele ukuba usebenzisa la mayeza. Oku kungasindisa ubomi bakho.
- Kuphephe ukukhulelwa ngokupheleleyo ngexesha lonyango kwaye emva kweenyanga ezi-3 uyekile.
- Funa ingcebiso kagqirha ngoko nangoko ukuba ufumana naziphi na iziphumo ebezingalindelekanga ezinzulu ezifana neempendulo eziqatha ze-allergy, iintlungu zesifuba, okanye ubunzima bokuphefumla.
- Ukuba unezinye iingxaki malunga nale mithi, ungathandabuzi ukuthetha nogqirha wakho uze uzisombulule.
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