Xa wena okanye umntu kusapho lwakho enyangwa isifo esifana neMultiple Myeloma, oogqirha badla ngokuthetha ngamayeza amatsha, anamandla. Kuqhelekile ukuba novalo kwaye ube nomdla ngamaxesha anje. Namhlanje, siza kuthetha ngelinye lamayeza anjalo, isitofu esibizwa ngokuba yiDaratumumab. Nangona liyeza elinzima, siza kuligcina lilula kwaye liqondakala.
Yintoni iDaratumumab?
Ngamafutshane, iDaratumumab luhlobo olukhethekileyo lwamayeza oluyilwe ukujolisa nokutshabalalisa iiseli zomhlaza. Kwizonyango, sibiza oku ngokuba yiMonoclonal Antibody . Khawuthelekelele ukuba inkqubo yomzimba wethu yokuzikhusela inamajoni abizwa ngokuba 'zii-antibodies'. Umsebenzi wawo kukufumana, ukubamba, nokutshabalalisa iintsholongwane ezibangela izifo. Ngoko ke, izazinzulu zenze i-antibody yokwenziwa kwilebhu enokwenza into efanayo, kodwa ijolisa kuphela kwiiseli zomhlaza . Yiyo loo nto le Monoclonal Antibody iyiyo.
I-Daratumumab isetyenziswa kakhulu ukunyanga uhlobo lomhlaza wegazi olubizwa ngokuba yiMultiple Myeloma . Lo ngumhlaza ochaphazela iiseli zeplasma kwi-bone mongo. Eli yeza linamathela kwiiseli zomhlaza kwaye lizinike imiqondiso kwinkqubo yomzimba wethu yokuzikhusela ukuba izitshabalalise. Eli yeza linokubulala iiseli zomhlaza ngokwalo.
Ngamanye amaxesha oogqirha banokukunika eli yeza nakwezinye iimeko zonyango. Ngoko ke ukuba unemibuzo, buza ugqirha wakho ngalo.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale unyango
Ngaphambi kokuba uqale amayeza anamandla kangaka, kubaluleke kakhulu ukwazisa ugqirha wakho ngembali yakho epheleleyo yempilo. Musa ukufihla nantoni na, nokuba zeziphi iinkcukacha ezincinci. Kuba olo lwazi luya kukunceda ukuba unyangwe ngokukhuselekileyo.
Qiniseka ukuba ukhankanya oku kulandelayo:
- Ii-Allergy: Ukuba une-allergy kungekuphela nje kwiDaratumumab, kodwa nakwisithako esithi "Sorbitol" esikweli yeza, nakweyiphi na enye iyeza, ukutya, idayi, okanye isigcini, nceda usixelele kuqala.
- Iintsholongwane Zangoku: Xelela ugqirha wakho ukuba okwangoku unezifo ezinje ngomkhuhlane, ukukhwehlela, okanye umkhuhlane. Ingakumbi ukuba ukhe waba nezifo ezinje nge-chickenpox, i-herpes, okanye i-hepatitis B, kufuneka wazise ugqirha wakho ngembali yakho.
- Iingxaki zokuphefumla: Ukuba unesifo semiphunga esihlala ixesha elide njenge-asthma okanye i-COPD, qiniseka ukuba uyayikhankanya loo nto.
- Ukukhulelwa nokuncancisa: Oku kubaluleke kakhulu ukuba ukhulelwe, uceba ukukhulelwa, okanye ungumama oncancisayo. Siza kuthetha ngale nto ngokweenkcukacha.
- Ukunganyamezeli iFructose ngokwelifa:Le yimeko engaqhelekanga kakhulu, efunyanwa njengelifa. Isithako `(Sorbitol)` esikweli yeza sinokubangela iingxaki kubantu abanale meko. Ngoko ke ukuba uyazi ukuba unesifo esinjalo, baxelele ngaso.
Ndingakunika njani eli yeza?
Eli yeza alilophilisi oliginyayo. Linikwa njengenaliti emthanjeni. Njengokunika ityuwa, ugqirha ufaka eli yeza emzimbeni. Oku sikubiza ngokuba yi-IV Infusion .
Olu nyango kufuneka lunikwe esibhedlele okanye kwikliniki ekhethekileyo, phantsi kweliso elipheleleyo loogqirha abaqeqeshiweyo kunye nabasebenzi bobuhlengikazi. Asinto inokwenziwa ekhaya.
Ekubeni oku kunikwe phantsi kweliso likagqirha, amathuba okuba ugqithise kakhulu aphantsi kakhulu. Nangona kunjalo, ukuba ukrokrela ukuba kukho into eyenzekileyo, yazisa abasebenzi bezonyango ngokukhawuleza. Kwimeko yongxamiseko, ungatsalela umnxeba iZiko loLwazi lweePoisons kwiSibhedlele sikaZwelonke saseColombo . Okanye, kufuneka uye kwiYunithi yoNyango oluNgxamisekileyo (ETU) ekufutshane.
Kubaluleke kakhulu ukuya kwimihla namaxesha onyango olucwangcisiweyo. Ukuba ngesizathu esithile awukwazi ukuya, nceda ufowunele ugqirha okanye iklinikhi kwangethuba uze ubazise.
Izinto ekufuneka uzilumkele ngakumbi xa ufumana unyango
Uvavanyo lwegazi kunye notofelo-gazi
Oku kubaluleke kakhulu. I-Daratumumab inokuchaphazela iziphumo zovavanyo lwakho lohlobo lwegazi. Esi siphumo sinokuhlala ukuya kuthi ga kwiinyanga ezi-6 emva kwedosi yakho yokugqibela.
Ngoko ke, ugqirha wakho uza kwenza uvavanyo lokuchonga igazi kunye novavanyo lokuthelekisa igazi aze agcine iirekhodi ngaphambi kokuba aqale unyango. Ukuba ufuna ukunikela ngegazi nangasiphi na isizathu, qiniseka ukuba wazisa bonke oogqirha kunye nabasebenzi babongikazi ukuba uthatha iDaratumumab. Oku kubalulekile kukhuseleko lwakho.
Ii-allergies kunye neempendulo zokufakwa kwe-infusion
Abanye abantu banokuba neempendulo ze-allergy okanye ii-infusion reaction xa benikwa iyeza. Ukunciphisa umngcipheko woku, ugqirha wakho uza kukunika amanye amayeza (ngaphambi kwamayeza) ngaphambi kokuba akunike i-Daratumumab. Landela imiyalelo ngokuchanekileyo. Ukuba ubuso bakho buba bomvu, burhawuzelela, bunobunzima bokuphefumla, okanye uzive unesizungu ngelixa kunikwa iyeza, xelela umongikazi ngoko nangoko.
Ukukhulelwa kunye nokuncancisa
Kubaluleke kakhulu: Ngelixa usela eli yeza kwaye emva kweenyanga ezi-3 emva kokuyeka unyangoKuphephe ukukhulelwa ngokupheleleyo ngelixa usebenzisa eli yeza. Eli yeza linokubangela ingozi enkulu kusana olungekazalwa. Ukuba uceba ukukhulelwa okanye ucinga ukuba ukhulelwe, xelela ugqirha wakho ngoko nangoko. Kwakhona, kuphephe ukuncancisa xa usebenzisa eli yeza.
Zithini iziphumo ebezingalindelekanga ezinokubakho?
Njengalo naliphi na iyeza, iDaratumumab inokubangela iziphumo ebezingalindelekanga. Nangona kunjalo, ayinguye wonke umntu ozifumanayo. Ezinye zinzima, ngelixa ezinye zincinci. Eyona nto ibalulekileyo kukuxelela ugqirha wakho ukuba ubona into engaqhelekanga.
| Iziphumo ebezingalindelekanga zeDaratumumab | |
|---|---|
| 🚨 Izinto ekufuneka uzixelele iqela lakho lezonyango ngoko nangoko | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi, ubunzima bokuphefumla. |
| Iimpendulo zokufakwa | Ukudinwa, iintlungu esifubeni, ubunzima bokuphefumla, uxinzelelo lwegazi oluphezulu, kunye nokucaphuka kusenokubakho ngexesha okanye emva nje kokuba unikwe iyeza. |
| Iimpawu zosulelo | Umkhuhlane, ukubanda, ukukhohlela, umphimbo obuhlungu, ukutsha xa uchama. |
| Ukopha okungaqhelekanga | Ukugruzuka kwesikhumba, ukopha kweentsini. |
| Umbono ofipheleyo | Umbono ofipheleyo. |
| 🙂 Izinto onokuzixelela ugqirha wakho ukuba azisoloko zinzulu, kodwa ziyaqhubeka | |
| Ukudinwa | Ukudinwa kakhulu nangona sele ndenze umsebenzi omncinci. |
| Iingxaki zenkqubo yokugaya ukutya | Ukuqhinwa okanye urhudo. |
| Utshintsho kwimilenze | Ukuba ndindisholo, iintlungu ezandleni nasezinyaweni, ukudumba emilenzeni nasemaqatheni. |
Ezinye iziphumo ebezingalindelekanga ezingadweliswanga kolu luhlu zinokwenzeka, ngoko thetha nogqirha wakho ngazo naziphi na iimpawu ezingaqhelekanga.
Umyalezo Wokuya Ekhaya
- I-Daratumumab yi-antibody ye-monoclonal ejolise kwiiseli zomhlaza kwaye isetyenziselwa ukunyanga umhlaza onjenge-multiple myeloma.
- Ngaphambi kokuba uqale unyango, xelela ugqirha wakho ngazo zonke iimeko zakho zempilo, ii-allergies, kunye nazo zonke ezinye iziyobisi ozisebenzisayo.
- Eli yeza lisenokuchaphazela uvavanyo lokujiya kwegazi, ngoko ke xelela abasebenzi bezonyango ukuba uthatha olu nyango.
- Kuphephe ukukhulelwa ngexesha lonyango kwaye emva kweenyanga ezi-3 emva kokuyeka.
- Ukuba ufumana naziphi na iziphumo ebezingalindelekanga ezinzulu ezifana nokunganyamezelani komzimba, ubunzima bokuphefumla, okanye umkhuhlane xa usela amayeza, yazisa ugqirha okanye abasebenzi bomongikazi ngokukhawuleza.
- Ukuya kwiindibano ezinikwe ngugqirha ngaphandle kokuphosa nanye into kubaluleke kakhulu kwimpumelelo yonyango.
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