Umhlobo olwa nentloko ebuhlungu: Masifunde ngeepilisi ze-Ergotamine Sublingual.

Xa unentloko ebuhlungu enganyamezelekiyo, ingaba yintlungu yokwenyani imini yonke, akunjalo? Ngamanye amaxesha intloko yakho ibuhlungu kangangokuba awukwazi nokujonga ukukhanya, uzive unesicaphucaphu, kwaye abanye abantu bade bahlanze. Kukho amaxesha apho ungakwazi ukwenza nto uze uhlale ebhedini imini yonke. Namhlanje, siza kuthetha ngamayeza akhethekileyo anokukunika isiqabu xa unentlungu enzima kangaka ye-migraine.

Luhlobo luni lonyango olu?

Eli yeza libizwa ngokuba yi-ergotamine . Lidla ngokuza njengepilisi engaphantsi kolwimi oyibeka phantsi kolwimi lwakho uze uyinyibilikise. Lenzelwe ngokukodwa ukukunceda ukulawula iintloko ezibuhlungu ezibangelwa yimigraines.

Ngamafutshane, eli yeza, i-Ergotamine, lenza izinto ezimbini engqondweni yakho. Enye kukuthintela iimpawu zentlungu ezibangela i-migraines. Enye kukwenza eminye yemithambo yegazi engqondweni idumbe, nto leyo ebangela ukuba loo mithambo yegazi inciphe. Likudidi lwamayeza abizwa ngokuba yi-ergot alkaloids .

Nangona kunjalo, kubaluleke kakhulu ukukhumbula oku: Eli yeza aliloyeza lokuthintela iintloko ezibuhlungu ngaphambi kokuba zenzeke. Oku kuthetha ukuba ufanele ulithathe emva kokuba uqalise ukuba nentloko ebuhlungu, oko kukuthi, emva kokuba uneempawu zentloko ebuhlungu. Akulunganga ukulithatha ulindele ukuba liza kwenzeka.

Ngamanye amaxesha ugqirha wakho angakunika eli yeza ngenye injongo. Ngoko ke ukuba unemibuzo okanye awuqinisekanga ngeli yeza, kungcono ubuze ugqirha wakho okanye ikhemisti. Uya kulifumana eli yeza phantsi kwegama lophawu 'Ergomar' .

Zeziphi izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba usebenzise eli yeza?

Kulungile, ngoku le yingongoma ebaluleke kakhulu. Ngaphambi kokuba uqale ukusebenzisa eli yeza le-Ergotamine, ukuba unezinye zezi meko zidweliswe ngezantsi, ngokuqinisekileyo kufuneka uxelele ugqirha wakho ngaphandle kokufihla nantoni na. Kuba kulapho kuphela apho ugqirha anokuthi agqibe khona ukuba eli yeza lifanelekile kuwe okanye akunjalo, okanye ukuba angalinika njani.

Ngoku jonga ukuba ezi zinto ziyasebenza na nakuwe:

• Ngaba uneentlungu esifubeni okanye unengxaki yokuphefumla?
• Ngaba unesifo sentliziyo okanye isifo semithambo yegazi?
• Ingaba unalo ifuthe eliphezulu?
• Ingaba unayo nayiphi na intsholongwane emzimbeni wakho, efana nokudumba?
• Ngaba unesifo sezintso?
• Ingaba kukho ingxaki ngesibindi, oko kukuthi isifo sesibindi?
• Ingaba ukujikeleza kwegazi akuhambi kakuhle? Oku kuthetha izinto ezifana nokuhamba kwegazi okungahambi kakuhle ukuya emalungwini akho, ukuba ndindisholo, njl.
• Ngaba ungumntu otshayayo? Ukutshaya kuyingozi enkulu kwisifo sentliziyo.
• Ngaba wakha waba ne-allergy okanye naluphi na olunye uphendulo olungaqhelekanga kolu yeza le-ergotamine, naluphi na olunye unyango, ukutya, iidayi, okanye izithinteli?
• Ngaba ukhulelwe okwangoku? Okanye uzama ukukhulelwa?
• Ingaba ungumama oncancisayo?

Ukuba kukho nayiphi na kwezi zinto ezikukhathazayo, nceda uxelele ugqirha wakho.

Ndingayisebenzisa njani le yeza?

Indlela elisetyenziswa ngayo eli yeza nayo ikhethekile kakhulu. Kubaluleke kakhulu ukulazi nokulenza ngokuchanekileyo.

• Indlela yokusela: Eli yeza lifanele lithathwe ngomlomo. Thatha ipilisi, uyibeke phantsi kolwimi lwakho , uze ulinde ide inyibilike ngokupheleleyo.
• Okona kubaluleke kakhulu: Musa ukuhlafuna okanye ukuginya ipilisi. Yivumele inyibilike phantsi kolwimi lwakho. Oku kuya kuqinisekisa ukuba iyeza lifunxwe ngokupheleleyo emzimbeni wakho.
• Landela imiyalelo: Landela imiyalelo ekwileyibhile kagqirha oyinikwe ngugqirha wakho ngokuchanekileyo.
• Ixesha elifanelekileyo: Ukuze ufumane iziphumo ezilungileyo, thatha eli yeza kwangoko nje ukuba uzive intloko ebuhlungu ebuhlungu, okanye kwangoko nje ukuba uzive iimpawu ezingaphambi kwentloko ebuhlungu (njenge-aura). Musa ukulibazisa. Kulapho ke liza kukunika isiqabu esingcono.
• Musa ukulisebenzisa rhoqo eli yeza: Eli yeza alenzelwanga ukuba lithathwe yonke imihla. Kwakhona, musa ukulisebenzisa ngaphezu kwedosi elichazwe ngugqirha wakho, kwaye awulisebenzisi ngaphezu kwenani lamaxesha ugqirha wakho akuxelela ukuba ulisebenzise ngosuku.
• Ukuba unika abantwana: Qiniseka ukuba uthetha neqela lakho lezempilo malunga nokunika abantwana abancinci eli yeza. Lingadinga ukhathalelo olukhethekileyo. Musa ukunika abantwana abancinci eli yeza ngaphandle kwengcebiso kagqirha.
• I-Overdose: Ukuba ucinga ukuba usele eli yeza kakhulu, fowunela iziko lolawulo lwetyhefu elikufutshane okanye igumbi likaxakeka ngoko nangoko. Okanye uye apho ngoko nangoko.
• Musa ukwabelana: Eli yeza lelakho kuphela. Musa ukulinika umhlobo okanye ilungu losapho, nokuba banomkhuhlane. Ayizizo zonke amayeza asebenzela wonke umntu.

Yintoni omawuyenze ukuba uphoswe yidosi?

Lo mbuzo awufanelekanga kangako kweli yeza. Kuba, njengoko bekutshiwo ngaphambili, eli asiloyeza elithathwa ngexesha elifanayo yonke imihla, ngendlela eqhelekileyo. Lithathwa kuphela xa intloko ibuhlungu ngeCawa.

Zeziphi ezinye izinto ezinokusebenzisana nale mithi? (Iindlela ezisetyenziswa ngayo)

Oku kukwayinto ekufuneka uyilumkele kakhulu. Kukho amayeza athile anokubangela iziphumo ebezingalindelekanga eziyingozi xa esetyenziswa nge-Ergotamine. Kwakhona, kukho amanye amayeza nokutya okunokuchaphazela indlela esebenza ngayo i-Ergotamine.

I-Ergotamine akufuneki isetyenziswe kunye namayeza alandelayo:

• I-Bromocriptine
• I-Ceritinib
• Amanye amayeza okubulala iintsholongwane, anjenge-clarithromycin kunye ne-erythromycin
• Amanye amayeza okubulala iintsholongwane anikwa i-HIV okanye i-hepatitis
• Amanye amayeza oxinzelelo lwegazi oluphezulu, isifo sentliziyo, kunye nokubetha kwentliziyo okungaqhelekanga
• Amanye amayeza osulelo lwefungus, njenge-itraconazole, i-ketoconazole, i-posaconazole, kunye ne-voriconazole
• Amanye amayeza anikwayo xa uphathwa yintloko ebuhlungu aquka: i-almotriptan, i-eletriptan, i-frovatriptan, i-naratriptan, i-rizatriptan, i-sumatriptan, kunye ne-zolmitriptan. La mayeza akwabizwa ngokuba yi-'triptans'.
• I-cocaine
• Idelalisib
• I-Imatinib
• I-Levoketoconazole
• I-Lonafarnib
• I-Mifepristone
• I-Pseudoephedrine (inokufumaneka kwamanye amayeza omkhuhlane)
• I-Ribociclib
• I-Tucatinib

Kwakhona, eli yeza linokusebenzisana nezinto ezilandelayo. Oku kuthetha ukuba iziphumo zinokwenzeka:

• Amanye amayeza okudakumba, ukuxhalaba, okanye iingxaki zengqondo
• I-Clotrimazole (iyeza lokulwa nentsholongwane)
• I-Fluconazole (iyeza lokulwa nentsholongwane)
• Ijusi yegrapefruit – Lumka kakhulu ngale. Ukusela ijusi yegrapefruit ngelixa uthatha i-ergotamine kunokunyusa iziphumo ebezingalindelekanga.
• I-Metronidazole (iyeza elisetyenziselwa izifo ezithile)
• I-Nicotine – Oku kuthetha iimveliso ezinxulumene necuba, ezifana neecuba.
• I-Propranolol (iyeza elisetyenziselwa ukunyanga isifo sentliziyo kunye noxinzelelo lwegazi oluphezulu)
• I-Zileuton (iyeza le-asthma)

Olu luhlu alubandakanyi zonke iindlela ezinokwenzeka zokusebenzisa amayeza. Ngoko ke, nika ugqirha wakho uluhlu olupheleleyo lwamayeza owasebenzisayo (kuquka lawo anxulumene nezinye izifo, iivithamini, imifuno, amayeza angagunyaziswanga ngugqirha, kunye nezongezo zokutya).Kwakhona, qiniseka ukuba uxelela ugqirha wakho ukuba uyatshaya, usela utywala, okanye usebenzisa iziyobisi ezingekho mthethweni, kuba ezinye izinto zinokuchaphazela amayeza akho kwaye zibangele iingxaki.

Zeziphi izinto ekufuneka uzilumkele xa usebenzisa eli yeza?

Kukho ezinye izinto ezimbalwa ekufuneka uziqwalasele xa usebenzisa i-ergotamine.

• Ukuba akukho ncedo: Ukuba eli yeza aliniki ncedo lukhulu kwiintloko zakho ze-migraine, okanye ukuba iintloko zakho ziqala ngendlela eyahlukileyo kunesiqhelo, thetha neqela lakho lezempilo. Kusenokufuneka utshintshele kwelinye iyeza okanye uzame indlela eyahlukileyo yonyango ukuze unyange iintloko zakho.
• Ukozela/Ukudinwa: Eli yeza linokukwenza uzive ulele okanye unesizungu. Ngoko ke, musa ukuqhuba, ukusebenzisa oomatshini abanzima, okanye ukwenza nantoni na efuna ukuphaphama kwengqondo ude wazi ukuba eli yeza likuchaphazela njani. Ukuze unciphise umngcipheko wokuba nesiyezi okanye ukuquleka, musa ukuphakama kwindawo ohleli kuyo okanye ume kuyo ngequbuliso. Yenza ezi zinto kancinci kancinci. Oku kubaluleke kakhulu ukuba umdala. Ukusela utywala kunokwenza oku kukozela, isizungu, kunye nokuhlambuluka kube mandundu. Ke ngoko, kuphephe ngokupheleleyo utywala ngelixa usebenzisa eli yeza.
• Ukujikeleza kwegazi: Eli yeza linokukunciphisa kancinci ukujikeleza kwegazi eluswini, kwiminwe nakwiinzwane. Oku kunokukwenza ube novelwano ngakumbi kumkhuhlane. Izandla neenyawo zakho zinokuziva zibanda kwaye zingabi nanto. Abantu abadala banokuba novelwano olunjalo. Ke ngoko , nxiba kakuhle kwaye uzigcine ufudumele kwimozulu ebandayo. Kuphephe ukuhlala ebanda ixesha elide.
• Intloko Ebuhlungu Esebenzisa Amayeza Ngokugqithisileyo: Le yingxaki ebaluleke kakhulu. Ukuba usebenzisa amayeza e-migraine (hayi nje i-ergotamine, kodwa nezinye iintlungu zentlungu) kangangeentsuku ezili-10 okanye ngaphezulu ngenyanga, iintloko zakho ezibuhlungu zinokuba mandundu endaweni yokuba zibe ngcono. Oku kubizwa ngokuba 'yintloko ebuhlungu esetyenziswa kakhulu ngamayeza'. Ke ngoko, luncedo kakhulu ukugcina idayari yentloko ebuhlungu, urekhoda iintsuku oneentloko ezibuhlungu ngazo, amayeza owaselayo, kunye nokuba angakanani. Ukuba ukuhlaselwa kwakho yi-migraine kuya kuxhaphaka, okanye ukuba indlela yakho yentloko iyatshintsha, qiniseka ukuba unxibelelana neqela lakho lezempilo kwaye ubazise.

Zithini iziphumo ebezingalindelekanga ezinokubakho zale yeza?

Njengalo naliphi na iyeza, i-ergotamine inokubangela iziphumo ebezingalindelekanga kwabanye abantu. Nangona kunjalo, ayinguye wonke umntu ozifumanayo. Ezinye iziphumo ebezingalindelekanga ziyingozi kwaye kufuneka ufune ingcebiso kagqirha ngokukhawuleza ukuba ziyavela. Ezinye azibi yingozi kwaye ziyanyamalala emva kweentsuku ezimbalwa.

Ukuba ufumana nayiphi na kwezi ziphumo ebezingalindelekanga zibi, kufuneka uxelele iqela lakho lezempilo ngokukhawuleza. Okanye uye kwisibhedlele esikufutshane:

• Iimpendulo ze-allergy: Ukurhawuzelela kwesikhumba, ukurhawuzelela, amaqhuqhuva, ukudumba kobuso, imilebe, ulwimi, okanye umqala. Ukuba umqala uyadumba, kunokwenza kube nzima nokuphefumla.
• Utshintsho kwimilenze: Ukutsha, iintlungu, ukurhawuzelela, okanye utshintsho lombala (njengokuba mhlophe, luhlaza okwesibhakabhaka) emilenzeni okanye emalungeni.
• Iimpawu zokuhlaselwa yintliziyo: Intlungu okanye ukuxinana esifubeni, intlungu esasazeka emagxeni, ezingalweni, entanyeni, okanye emhlathini, isicaphucaphu, ukuphefumla kancinci, ulusu olubandayo okanye oluxineneyo, ukutyhafa, okanye ukuziva ngequbuliso unesicaphucaphu.
• Utshintsho lwesingqi sentliziyo: Ukunyuka ngequbuliso kwesantya sentliziyo (ukubetha kwentliziyo okukhawulezayo), ukuziva ngathi kubetha ngokungacwangciswanga (ukubetha kwentliziyo okungacwangciswanga), isiyezi, ukuquleka, iintlungu zesifuba, ubunzima bokuphefumla.
• Ukunyuka ngequbuliso koxinzelelo lwegazi.
• Isiganeko sikaRaynaud: Iminwe okanye iinzwane zivakala zibanda, zingenamsebenzi, kwaye zibuhlungu. Umbala weminwe unokutshintsha ukusuka ekubeni luhlaza okwesibhakabhaka ukuya kubomvu, uze ube bomvu.
• Iimpawu zesifo sokuwa (Ukuxhuzula): Oku kuthetha ukuba ziza njengokuxhuzula.
• Iimpawu zestroke: Ukungaziva okanye ubuthathaka bobuso, ingalo, okanye umlenze ngequbuliso (ngesiqhelo kwicala elinye lomzimba), iingxaki zokuthetha, intetho engacacanga, ukudideka, iingxaki zokuhamba, ukulahlekelwa kukulinganisela okanye ukulungelelanisa, isiyezi, intloko ebuhlungu ephuma ngaphandle kwesizathu, kunye notshintsho olukhawulezileyo embonweni.
• Intlungu ebuhlungu esiswini: Intlungu ebuhlungu ngequbuliso, isisu esibuhlungu, urhudo olunegazi, umkhuhlane, isicaphucaphu, kunye nokuhlanza.
• Ukulahlekelwa ngumbono: Ukulahlekelwa ngumbono ngequbuliso, okanye ukulahlekelwa ngumbono ngokupheleleyo.

Iziphumo ebezingalindelekanga ezihlala zingadingi nyango, kodwa kufuneka uxelele iqela lakho lezempilo ukuba ziyaqhubeka okanye ziyakukhathaza:

• Isiyezi
• Ukungonwabi okanye ukudinwa ngokubanzi
• Isicaphucaphu
• Ukuhlanza

Olu luhlu luquka ezimbalwa zeziphumo ebezingalindelekanga ezinokubakho. Ayizizo zonke iziphumo ebezingalindelekanga ezidweliswe apha. Ukuba ubona nantoni na engaqhelekanga, funa ingcebiso kagqirha. Ungayixela iziphumo ebezingalindelekanga kwi-FDA (Food and Drug Administration) e-United States ku-1-800-FDA-1088. ESri Lanka, kungcono ukuyixela kugqirha wakho okanye esibhedlele.

Ndingawagcina njani amayeza am?

Kubaluleke kakhulu ukugcina amayeza akho ngokufanelekileyo.

• Gcina kude nabantwana: Yigcine kwindawo apho abantwana abancinci bangenakuyifikelela khona, njengaphezulu.
• Ubushushu: Gcina kubushushu begumbi, obuphakathi kwe-15 kunye ne-30 degrees Celsius (59 kunye ne-86 degrees Fahrenheit).
• Ukupakisha: Gcina kwiphakheji yefoyile efike ide ilungele ukusetyenziswa. Musa ukususa iipilisi.
• Ukhuseleko: Zikhusele ekukhanyeni nasekufumeni. Musa ukuzigcina kwiindawo ezifumileyo ezifana negumbi lokuhlambela.
• Ukuphelelwa: Jonga umhla wokuphelelwa kweyeza kwiphakheji yamayeza. Musa ukusebenzisa naliphi na iyeza elidlulile kuloo mhla uze ulilahle.

Olu lwazi lushwankathelo kuphela. Lusenokungabandakanyi yonke into. Ukuba unemibuzo okanye iinkxalabo malunga nalo mayeza, nceda uthethe nogqirha wakho, ikhemisti, okanye omnye umboneleli wezempilo.

Izinto ezibalulekileyo ekufuneka sizikhumbule (Umyalezo Wokuya Ekhaya)

Kulungile, masiphinde sichaze amanqaku abalulekileyo malunga ne-Ergotamine esithethe ngayo namhlanje, akunjalo?

• I-Ergotamine liyeza elinikwa ukulawula iintlungu zentloko ebuhlungu xa sele iqalile. Alisetyenziswa ukuthintela iintloko ezibuhlungu.
• Le pilisi mayibekwe phantsi kolwimi ize ivunyelwe ukuba inyibilike ngokupheleleyo. Musa ukuyihlafuna okanye ukuyiginya.
• Qiniseka ukuba uxelela ugqirha wakho ngazo naziphi na ezinye iingxaki zempilo onazo (ingakumbi isifo sentliziyo, uxinzelelo lwegazi oluphezulu, iingxaki zokujikeleza kwegazi), naziphi na ezinye iziyobisi ozisebenzisayo ngoku, kunye nazo naziphi na izinto ezibangela ukuba umzimba wakho ungabi namdla.
• Eli yeza linokusebenzisana namanye amayeza amaninzi. Ngoko ke thetha nogqirha wakho ngalo mba. Kufuneka ulumke ngakumbi ngejusi yegrapefruit.
• Ukusela iyeza kunokubangela ukozela kunye nesiyezi. Ngoko ke, lumka xa uqhuba okanye usenza umsebenzi ofuna ukugxila.
• Ukusebenzisa kakhulu eli yeza kunokubangela ukuba intloko yakho ye-migraine ibe mandundu. Ngoko ke lisebenzise kuphela njengoko ugqirha wakho ekuyalele.
• Ukuba ufumana naziphi na iimpawu zesiphumo esibi kakhulu (ezifana neentlungu zesifuba, ubunzima bokuphefumla, ukusabela kwe-allergy, okanye iimpawu ze-stroke) , funa ingcebiso kagqirha ngokukhawuleza.
• Eli yeza lelakho wedwa. Musa ukulinika omnye umntu.

Ngoko ke, i-migraine yimeko abantu abaninzi abajongene nayo. Nangona kunjalo, ngokuxilongwa ngokufanelekileyo kunye nonyango, ungayilawula intlungu kwaye uphile ubomi obuqhelekileyo. Ukuba nawe uphethwe yi-migraine, kungcono ukubona ugqirha kwaye ufumane ingcebiso.

i- ergotamine, i-migraine, intloko ebuhlungu, amayeza, iziphumo ebezingalindelekanga, ulwimi olungaphantsi