Ngaba imithambo yakho yegazi ingonakalisa nemithambo yegazi? Masithethe ngeFibrinoid Necrosis!

Imithambo yegazi emincinci esasazeke emzimbeni wethu ifana nemibhobho ethwala amanzi. Le yileyo ithwala igazi iye kuzo zonke iindawo zomzimba wethu. Ngoko ke, kwenzeka ntoni ukuba kukho into eyonakalisayo le mithambo yegazi? Namhlanje siza kuthetha ngemeko enokuba yingozi, kwaye yimeko ebizwa ngokuba yiFibrinoid Necrosis . Musa ukoyika, masiyiqonde le nto ngokulula.

Yintoni i-fibrinoid necrosis?

Ngamafutshane, i-fibrinoid necrosis kukonakalisa iindonga zangaphakathi zemithambo yegazi emincinci emizimbeni yethu, ingakumbi imithambo emincinci . Cinga ngayo njengokuqhuma kombhobho wamanzi. Xa imithambo yegazi yonakele ngale ndlela, inokuqhekeka, yenzakale , yophe igazi, kwaye ide ivuthuluke ngaphakathi emzimbeni.

Igama elithi “necrosis” lithetha ukufa kweeseli . Lithetha ukufa kweeseli ngenxa yengozi, ukwenzakala, okanye ukulahleka kwegazi. I-Fibrinoid necrosis yinto efanayo, nto leyo ethetha ukuba iiseli ezisezindongeni zemithambo yegazi ziyafa.

Ivela njani le meko?

Oku kungabonakala kunzima kancinci, kodwa cinga ngale ndlela. Sinenkqubo yokuzikhusela emizimbeni yethu. Ifana namandla okuzikhusela emizimbeni yethu. Yile nkqubo esikhusela kwizifo . Kodwa ngamanye amaxesha le nkqubo yokuzikhusela iba namandla okanye idideke.

Kwi-fibrinoid necrosis, inkqubo yomzimba yokuzikhusela isebenza kakhulu ize ikhuphe izinto ezithile. Ezi zinto zinamathela eludongeni lwangaphakathi lwemithambo yegazi yethu. Emva koko kukho ukudumba , oko kuthetha ukudumba nokubomvu. Oku kudumba kubangela ukuba iiseli ezikwidonga lemithambo yegazi zife. Ngamanye amazwi, kufana nokuba ukhuselo lwethu luhlasela iiseli zethu.

Yintoni ebangela i-fibrinoid necrosis?

Nasiphi na imeko enokonakalisa imithambo yegazi inokubangela oku. Kukho izinto ezininzi eziphambili ezibangela oku:

• Uxinzelelo lwegazi oluphezulu kakhulu: Oku kubizwa ngokuba yi- (Malignant Hypertension) okanye (Hypertensive Crisis) . Ngokwesiqhelo, uxinzelelo lwegazi lomntu ophilileyo kufuneka lube ngaphantsi kwe-130/80 mmHg. Nangona kunjalo, kule meko ebizwa ngokuba yi-(Malignant Hypertension), uxinzelelo lwegazi lunyuka luye kwi-180/120 mmHg nangaphezulu. Xa oku kusenzeka,I-Fibrinoid necrosis inokwenzeka xa imithambo yegazi ehambisa igazi kwizitho ezibalulekileyo ezifana nentliziyo , ingqondo, kunye nezintso yonakele. Le yingxamiseko enkulu kakhulu kwaye ifuna unyango olukhawulezileyo.

• Izifo ezizikhusela ngokwazo : Njengoko bekutshiwo ngaphambili, ezi zizifo apho amajoni ethu omzimba ahlasela khona imizimba yethu. Umzekelo:
• (Irheumatoid arthritis )
• (Lupus) (Isifo seLupus – sichaphazela amalungu amaninzi afana nolusu, amalungu, izintso)
• (I-Rheumatic Fever – imeko enokwenzeka emva kokosuleleka emqaleni kwaye ichaphazele intliziyo)

• I-Preeclampsia: Le yimeko eyenzeka kwabanye oomama ngexesha lokukhulelwa. Ibonakala ngoxinzelelo lwegazi oluphezulu kunye nezinye iimpawu.

• (I-Subacute Bacterial Endocarditis): Olu lusulelo lwebhaktiriya olukwindawo engaphakathi yentliziyo.

• I-Vasculitis: Ngamafutshane, kukudumba kwemithambo yegazi, oko kuthetha ukudumba. Imizekelo yoku ibandakanya:
• (I-Polyarteritis Nodosa)
• (IgA Vasculitis) (eyayisaziwa ngokuba yiHenoch-Schönlein purpura)

Ngoku mhlawumbi uyaqonda ukuba le meko ayibangelwanga sisizathu esinye kuphela, kodwa inokunxulunyaniswa nezifo ezahlukeneyo.

Zithini iimpawu zale meko?

Ngenxa yokuba i-fibrinoid necrosis yonakalisa imithambo yegazi, uphawu oluphambili kukopha . Oku kunokwenzeka ngeendlela ezahlukeneyo:

• Iintsini eziphuma igazi.
• Igazi elikwisitulo (elimnyama okanye elibomvu ngokumnyama).
• Igazi kumchamo – siwubiza ngokuba yi -Hematuria .
• Ukugruzuka kwiindawo ezahlukeneyo emzimbeni (ngokungathi kugruzukile ngaphandle kokubethwa naphi na).
• Ukopha ngaphakathi emzimbeni (oku akubonakali ngaphandle, kodwa kunokuqondwa kwezinye iimpawu).
• Ukopha empumlweni.

Ukuba unesifo sokopha ngolu hlobo, musa ukusityeshela . Kubaluleke kakhulu ukufuna ingcebiso kagqirha.

Ziziphi iingxaki ezinokubakho zeFibrinoid Necrosis?

Iingxaki ezibangelwa yile meko zihlala zixhomekeke kwisifo esibangele le meko. Umzekelo, cinga ngale nto:

• Leyo sithethe ngayo (iMalignant Hypertension) , oko kukuthi, ukuba i-fibrinoid necrosis iyenzeka kwimithambo yegazi yezintso ngenxa yoxinzelelo lwegazi oluphezulu, inokukhokelela ekungasebenzini kwezintso .
• Ukuba le meko ibangelwa sisifo esifana ne -lupus , izilonda zesikhumba kunye nesifo sentliziyo zinokwenzeka.

Oko kuthetha ukuba iingxaki azimiselwa kuphela yi-fibrinoid necrosis, kodwa zikwamiselwa nasisifo esisisiseko.

Sifunyaniswa njani esi sifo? (Ukuxilongwa)

Xa iiseli zisifa, zikhupha into ebizwa ngokuba yi-fibrin . Le nto ebizwa ngokuba yi-fibrin bubungqina obuphambili bokuchonga esi sifo.

Iingcali zezifo , eziziingcali ekuxilongeni izifo, zithatha isampuli yezicubu ezonakeleyo zize ziyijonge phantsi kwe-microscope. Emva koko zinokubona ukuba le nto (i-Fibrin) ifakiwe na.

Ukuthathwa kwesampuli yethishu kubizwa ngokuba yi-biopsy . Indlela le biopsy eyenziwa ngayo iyahluka ngokuxhomekeke kwindawo esikuyo isifo:

• Iibhayopsy zesikhumba: Umaleko omncinci wesikhumba unokukhuhla phezu kolusu, okanye iqhekeza elincinci lithathwe ngesixhobo esikhethekileyo (isixhobo sokubhoboza). Ngamanye amaxesha kunokwenziwa i-incision encinci ukuze kuthathwe isampuli ukusuka nzulu.
• Iibhayopsy zangaphakathi: Ukuze bathathe isampuli yezicubu kwisitho esingaphakathi emzimbeni, oogqirha basebenzisa inaliti okanye isixhobo esibizwa ngokuba yi-endoscope . I-endoscope yityhubhu encinci enekhamera kunye nezixhobo ezincinci kwelinye icala. Oku kungadluliselwa ngaphakathi emzimbeni ukuze kuthathwe isampuli yezicubu.

Indlela yokunyanga? (Unyango)

Inyaniso kukuba, akukho nyango luthile noluqhelekileyo lwe-fibrinoid necrosis. Nangona kunjalo, oogqirha banokulawula ukopha . Kuxhomekeke kwindawo kunye nohlobo lokopha.

Ukongeza, eyona nto ibalulekileyo kukunyangelwa isifo esibangela i-fibrinoid necrosis .

Umzekelo, ukuba uxinzelelo lwegazi oluphezulu luyimbangela, kunikwa amayeza okulawula olu xinzelelo. Ukuba yingxaki kwinkqubo yomzimba yokuzikhusela, kukho amayeza okulawula olu xinzelelo nokuthintela umonakalo ongakumbi kwimithambo yegazi.

Ngoko ke, ingqwalasela ephambili yonyango kunyango lwesizathu esiyintloko .

Ungazikhusela njani kwi-fibrinoid necrosis? (Ukuthintela)

Endaweni yokuzama ukuzikhusela ngokupheleleyo koku, eyona nto ingcono onokuyenza kukunciphisa umngcipheko wokufumana iimeko ezibangela oku.

• Bona ugqirha wakho rhoqo ukuze akuxilonge. Ngale ndlela, ukuba kukho ingxaki yempilo, inokuchongwa ize inyangwe ngaphambi kokuba ibe yingozi.
• Ukuba sele unemeko enokubangela oku (umz. uxinzelelo lwegazi oluphezulu, isifo seswekile, isifo sokuzikhusela komzimba), landela imiyalelo kagqirha wakho ngokuchanekileyo . Sela amayeza akho ngexesha kwaye ugcine indlela yakho yokuphila njengoko uyalelwe.

Liyintoni ikamva lomntu onesi sifo? (Ingqikelelo)

Oku kuxhomekeke kakhulu kubunzulu bemeko ebangela i-fibrinoid necrosis. Ezinye iimeko zinokuba zezobomi bonke, zinciphise umgangatho wobomi, kwaye zinokubangela nokufa ngaphambi kwexesha.

Umzekelo, ukuba imeko ekhankanyiweyo apha ngasentla (iMalignant Hypertension) ayinyangwa ngokukhawuleza, ixesha lokuphila kwesigulana linokwehliswa ukuya kuthi ga kwiminyaka emibini. Yiyo loo nto kubalulekile ukufuna iingcebiso zonyango ngokukhawuleza xa kuvela iimpawu.

Ufanele uye nini kugqirha?

Ukuba ukhe wafumanisa ukuba unemithambo yegazi eyonakeleyo, okanye ukuba unayo nayiphi na kwezi mpawu zikhankanyiweyo ngaphambili (ingakumbi ukopha okungachazwanga), kubalulekile ukubona ugqirha ukuze kulandelwe ngokufanelekileyo.

Ngokulandela isicwangciso sonyango esichazwe ngugqirha wakho, ungayilawula imeko yakho kwaye uthintele umonakalo ongakumbi.

I-Fibrinoid necrosis yimeko eyonakalisa imithambo yegazi. Iimeko ezibangela oku zinokuba zimbi kakhulu, ngoko ke kufuneka uhlolwe ngugqirha ngokusondeleyo. Ngokubona ugqirha wakho rhoqo, unokulawula impilo yakho ngcono kwaye uthintele iingxaki ezivela kwiimeko ezingaphantsi.

Umyalezo Wokuya Ekhaya

• I-Fibrinoid necrosis kukonakalisa imithambo yegazi emincinci.
• Izizathu eziphambili zoku zizifo ezifana noxinzelelo lwegazi oluphezulu kunye nezifo zokuzikhusela komzimba.
• Uphawu oluphambili ziintlobo ezahlukeneyo zokopha.
• Kunokufuneka i-biopsy ukuze kufunyaniswe isifo.
• Unyango lujoliswe ikakhulu kwisizathu esiyintloko.
• Kubaluleke kakhulu ukufuna ingcebiso kagqirha ukuba uneempawu okanye izinto ezinokubangela umngcipheko, kuba oko kunokuba yingozi kakhulu ukuba akunakwa.

Ndiyathemba ukuba olu lwazi luluncedo kuwe. Hlala usempilweni!