Ngaba ukhe weva ngalo mhlaza ungaqhelekanga we-thyroid gland yakho? (Hürthle Cell Carcinoma) – Masithethe ngokweenkcukacha!

Ngaba wakha waziva iqhuma ngaphambili entanyeni yakho, ngaphantsi nje kwethambo lakho lentamo? Okanye uziva izinto ezifana nokutshintsha kwelizwi lakho, ubunzima bokuginya, okanye ukuphefumla kancinci? Nangona sisenokungazinaki kangako ezi zinto, zinokuba ziimpawu zohlobo lomhlaza olungaqhelekanga kodwa oluqhelekileyo . Namhlanje siza kuthetha ngomhlaza ongaqhelekanga kodwa ophathelelene nomhlaza okhula kwi-thyroid gland yethu. Loo ngumhlaza we-Hürthle Cell.

Yintoni iHürthle Cell Carcinoma?

Ngamafutshane, olu luhlobo lomhlaza olungaqhelekanga nolukhula ngokukhawuleza oluvela kwi-thyroid gland . Uyazi, i-thyroid yi-gland encinci, efana nebhabhathane engaphambili entanyeni yethu. Iihomoni ezikhuphayo zinceda ukulawula imisebenzi emininzi ebalulekileyo emzimbeni wethu, ngakumbi imetabolism.

Ngoko ke, xa kuvela le Hürthle Cell Carcinoma, izinto ezifana namaqhuqhuva e-thyroid zinokwakheka. Xa la maqhuqhuva ekhula, anokwenza kube nzima ngathi ukuthetha okanye nokuphefumla. Ukuba anganyangwa ngokufanelekileyo, lo mhlaza ungasasazeka kwezinye iindawo zomzimba, ezinje ngamaqhuqhuva e-lymph, imiphunga, namathambo . Oogqirha badla ngokunyanga lo mhlaza ngokwenza utyando lokususa yonke okanye inxalenye ye-thyroid gland.

Le meko ichaphazela njani umzimba wam?

Khawucinge nje, abanye abantu basenokungaluboni utshintsho emizimbeni yabo kwasekuqaleni nokuba baneHürthle Cell Carcinoma. Ngamanye amaxesha ifunyanwa ngengozi ngexesha lovavanyo lwesinye isifo.

Kodwa xa iimpawu ziqala ukubonakala, zisenokuqala zibonakale njengeziqwenga ezincinci ngaphambili entanyeni, apho kukho i-thyroid gland. Njengoko ezi thumba zikhula, zinokucinezela umphimbo wethu, zenze kube nzima ukuginya ukutya, nakwi-trachea yethu, zenze kube nzima ukuphefumla. Kwakhona, ukuba ezi thumba zicinezela kwiintambo zethu zelizwi, kunokubakho utshintsho kwilizwi lethu. Kusenokuvakala ngathi ilizwi lakho liyarhawuzelela xa unomkhuhlane .

Ngaba ii-Hürthle Cell Tumors zihlala ziyiCancer?

Nantsi ingongoma ebalulekileyo. Ii-tumor ze-Hürthle cell zinokuba zezomhlaza okanye ezingezizo ezomhlaza . Okumangalisayo kukuba, iimpawu zazo zombini ezi ntlobo zinokufana kakhulu. Ke ngoko, ngamanye amaxesha kunzima koogqirha ukufumanisa ngokuqinisekileyo ukuba i-tumor inomhlaza okanye ayisiyo ngokuyijonga nje. Ukuze baqiniseke, kufuneka bahlole iiseli ezivela kwi-tumor phantsi kwe-microscope .

Ngubani onokuba nethuba elikhulu lokufumana esi sifo?

Enyanisweni, nabani na angába neHürthle Cell Carcinoma. Nangona kunjalo,Ixhaphake kakhulu kubantu abaneminyaka engaphezu kwama-55 ubudala. Kuthiwa abafazi banamathuba amaninzi okufumana esi sifo kunamadoda.

Ingaba le yimeko eqhelekileyo?

Hayi, le ayisiyonto ixhaphakileyo . Ngokwesiqhelo, malunga nabantu abali-14 kwi-100,000 baxelwa ukuba banomhlaza we-thyroid minyaka le. Phakathi kwazo zonke ezi cancer ze-thyroid, le Hürthle Cell Carcinoma ifumaneka kwipesenti encinci kakhulu, malunga ne-3% . Oko kuthetha ukuba ayiqhelekanga kangako.

Zithini iimpawu zeHürthle Cell Carcinoma?

Amaxesha amaninzi, abantu abanale meko ababi nazimpawu de umhlaza ube mkhulu ngokwaneleyo ukuba uchaphazele amanye amalungu omzimba . Umzekelo, utshintsho kwilizwi lwenzeka xa ithumba licinezela iintambo zelizwi. Ezinye iimpawu zingabandakanya:

• Ubunzima bokuphefumla okanye bokuginya (dysphagia) . Kusenokuvakala ngathi kukho into ebambeke emqaleni wakho.
• Ukuziva ngathi umqala wakho uvalekile.
• Iqhuma elibuhlungu ngaphambili entanyeni, ngaphantsi kwe-apile ka-Adam.
• Ii-lymph nodes ezivuvukileyo.
• Ukuziva udiniwe ngalo lonke ixesha (Ukudinwa).
• Ukuba mncinci ngaphandle kwenjongo okanye isizathu .

Yintoni ebangela lo mhlaza?

Abaphandi bezonyango abakakwazi ukufumana unobangela oqinisekileyo wale meko. Nangona kunjalo, bachonge ezinye izinto ezinokubangela umngcipheko wokufumana esi sifo. Ezi ziquka:

• Ukuba nembali yosapho lwakho yomhlaza we-thyroid : Oku kuthetha ukuba umama wakho, utata wakho, okanye abantakwenu bakha baba nomhlaza we-thyroid.
• Ukunqongophala kwe-iodine ixesha elide : I-iodine yiminerali ebalulekileyo efunekayo emzimbeni wethu ukuze senze iihomoni ze-thyroid. Siyifumana ekutyeni esikutyayo.
• Ukuvezwa kwimitha : Oogqirha abaninzi bakholelwa ukuba ukuvezwa kwi-X-ray okanye unyango lwemitha kwizinto ezinje ngomhlaza kwandisa umngcipheko wokufumana i-Hürthle Cell Carcinoma.

Oogqirha bayixilonga njani le sifo?

Oogqirha bafumanisa le meko ngokukuxilonga kuqala, bebuza ngeempawu zakho, imbali yakho yezonyango, kunye nembali yezonyango yosapho lwakho. Emva koko banokwenza uvavanyo olufana nolu:

• Uvavanyo lwegazi : I-thyroid gland esempilweni ivelisa iproteni ebizwa ngokuba yi-thyroglobulin. Oogqirha baya kujonga inqanaba le-thyroglobulin egazini lakho. Ukuba eli nqanaba liphezulu, linokuba luphawu lwe-Hürthle Cell Carcinoma.
• Iskeni yokufunxwa kwe-thyroid: Olu vavanyo lusetyenziselwa ukujonga iiseli zomhlaza kwi-thyroid gland yakho. Kolu vavanyo, kufakwa inani elincinci le-iodine ene-radioactive egazini lakho. Le iodine iqokelelana kwizicubu zomhlaza kwi-thyroid gland yakho. Emva koko, kwenziwa i-positron emission tomography scan (i-PET scan) ukuze kufunyanwe iindawo ezikuyo iiseli zomhlaza.
• I-Laryngoscopy : Olu vavanyo luvumela oogqirha ukuba bahlole iintambo zakho zelizwi.
• Ukufunxwa kwenaliti encinci (i-FNA) : Kule nkqubo, ugqirha usebenzisa inaliti encinci kakhulu, ebhityileyo ukususa isampuli yezicubu kwi-thyroid gland yakho. Emva koko izicubu zihlolwa nge-microscope ukujonga iimpawu zomhlaza. Oku ngamanye amaxesha kubizwa ngokuba yi-needle biopsy .
• Utyando lweLobectomy : Ngamanye amaxesha, iziphumo zovavanyo lwe-FNA azanelanga ukuba oogqirha bafikelele kwisigqibo esiqinisekileyo. Kwimeko enjalo, baya kwenza utyando lokususa inxalenye ye-thyroid gland abacinga ukuba inomhlaza baze bayihlole.
• I-CT scan : Ukuba uvavanyo luqinisekisa ukuba une-Hürthle Cell Carcinoma, oogqirha baya kwenza olunye uvavanyo lokufota, olufana ne-CT scan, ukuze babone ukuba umhlaza usasazeke na kwezinye iindawo.

Ngaba kukho amanqanaba e-Hürthle Cell Carcinoma?

Ewe, ngokuqinisekileyo. Oogqirha basebenzisa ezi nkqubo zokulinganisa umhlaza ukucwangcisa unyango lomhlaza. Basebenzisa inkqubo yokulinganisa i-TNM ukwahlula i-Hürthle Cell Carcinoma. (U-T umele i-Tumor. U-N umele i-Lymph Node Involvement. U-M umele i-Metastasis.) Kukho izigaba zalo mhlaza ukusuka ku-I (enye) ukuya ku-IV (ezine).

Oogqirha bakwaqwalasela nobudala besigulana xa bechonga la manqanaba. Abantu abafunyenwe benesifo xa beneminyaka engama-55 okanye ngaphantsi, nokuba singakanani na ithumba, ukuba lichaphazele ii-lymph nodes, kwaye ukuba alisasazekanga kwiindawo ezikude, bahlelwa njengesigaba soku-1 (esokuqala). Nangona kunjalo, ukuba ithumba lisasazeke kwii-lymph nodes ezikude okanye kwezinye izitho zomzimba, abantu abaneminyaka engama-55 okanye ngaphantsi bahlelwa njengesigaba sesi-2 (esi-2).

Kalula nje:

Ubungakanani bethumba (T - Ithumba)

Oku kukuxelela ukuba umhlaza mkhulu kangakanani na kwaye nokuba usasazeke ngaphaya kwe-thyroid gland. Oku kuyahluka ukusuka kwiithumba ezincinci (umz., ngaphantsi kweesentimitha ezi-2 - `TI`) ukuya kwiithumba ezinkulu (`TIVa`, `TIVb`) ezisasazeke kwizicubu ezikufutshane entanyeni, kwi-trachea, okanye kwi-esophagus.

Impembelelo kwi-lymph nodes (N - Lymph Node)

Oku kujonga ukuba ingaba umhlaza usasazeke na kwiindawo ze-lymph ezikufutshane (`N0` - azisasazekanga,`NI` - zisasazekile). Ukuba usasazekile, kujonga nokuba uphakathi entanyeni (`NIa`) okanye emacaleni (`NIb`).

Ukusasazeka komhlaza (M - Metastasis)

Oku kukuxelela ukuba umhlaza usasazeke ngaphaya kwe-thyroid gland kunye nee-lymph nodes ezikufutshane ukuya kwizitho ezikude emzimbeni (umz. imiphunga, amathambo) . (`M0` - akukho kusasazeka kude,` MI` - kusasazeka kude).

Ugqirha usebenzisa olu lwazi ``(TNM)``` ukuze afumanise inqanaba lokugqibela lomhlaza wakho (iSigaba I, II, III, okanye IV). Oku kubaluleke kakhulu ekucwangciseni unyango.

Oogqirha baphatha njani oku?

Unyango oluphambili noluqhelekileyo lwale meko lutyando . Ngokuxhomekeke kwimeko yakho, oogqirha botyando banokususa yonke okanye inxalenye yendlala yakho yegilo. Banokususa nee-lymph nodes apho umhlaza usasazeke khona. Olu tyando lwegilo yegilo lunokususa ngokupheleleyo umhlaza.

Emva kotyando, unganikwa amayeza okuthintela i-thyroid gland yakho ekuveliseni iihomoni ukunciphisa amathuba okuba umhlaza ubuye . Ukongeza, kukho nezinye iindlela zonyango, ezifana nezi:

• Unyango lweehomoni : Oku kutshabalalisa iiseli zomhlaza okanye kuzithintele ekukhuleni kwazo.
• Unyango lwe-iodine olusebenzisa imisebe : Olu nyango lutshabalalisa iiseli zomhlaza we-thyroid.

Ngaba i-Hürthle Cell Carcinoma inganyangeka ngokupheleleyo?

Ewe, le yimeko enokunyangeka . Utyando lokususa yonke okanye inxalenye ye-thyroid gland luya kuyisusa umhlaza. Nangona kunjalo, ukuba wenze olu tyando, kuya kufuneka uthathe amayeza ubomi bakho bonke ukuze wenze iihomoni ze-thyroid ezaneleyo emzimbeni wakho.

Ungayinciphisa njani ingozi yokuhlaselwa sesi sifo?

Akukho ndlela ithile yokunciphisa umngcipheko wakho wokuba nale meko. Abanye abantu bakhula nale meko kuba iintsapho zabo zinembali yomhlaza we-thyroid. Ukuba unale meko, kungcono ukuthetha nogqirha wakho malunga neempawu ezinokuba ziimpawu zeHürthle Cell Carcinoma.

Lingakanani izinga lokusinda kwesi sifo?

Uphando lwakutshanje lubonise ukuba ama-95% abantu abanale meko basaphila emva kweminyaka emihlanu bexilongiwe . Kwaye olo phando lubonise ukuba ama-93% basaphila emva kweminyaka elishumi . Oko kuyaqinisekisa ngokwenene, akunjalo?

Ndingazinyamekela njani? / Kwenzeka ntoni emva konyango?

Kuxhomekeke kunyango lwakho, kunokufuneka uthathe amayeza okutshintsha i-thyroid hormone ubomi bakho bonke . Kwakhona, i-Hürthle Cell Carcinoma ingabuya ngamanye amaxesha. Ngoko ke, buza ugqirha wakho ukuba zeziphi iimpawu ezinokubonisa ukuphinda kwesifo .

I-Hürthle Cell Carcinoma luhlobo olungaqhelekanga lomhlaza we-thyroid. Ukuba uneempawu, ugqirha wakho unokufuna ukwenza utyando lwe-thyroid ukuqinisekisa ukuba unayo le meko. Kwiimeko ezininzi, utyando lokufumanisa imeko luya kuyisombulula ingxaki . Nangona kunjalo, utyando lodwa aluyi kuzisombulula zonke iingxaki ezibangelwa yi-Hürthle Cell Carcinoma.

Abantu abaye benza utyando lwe-thyroid kuya kufuneka bathathe amayeza e-hormone ubomi babo bonke. Kwakhona, lo mhlaza ungabuya emva konyango. Ukuba unale meko, nceda ukhumbule ukuba oogqirha bakho bahlala bekulungele ukukunceda nokukuxhasa , ingakumbi ukuba isifo siphinda sibuye.

Ezona zinto zibalulekileyo ekufuneka uzikhumbule kweli nqaku

Kulungile, masishwankathele ezinye zezona zinto zibalulekileyo ekufuneka uzikhumbule koko sithethe ngako:

• I-Hürthle Cell Carcinoma luhlobo lomhlaza we-thyroid olungaqhelekanga, kodwa olunobundlongondlongo ngakumbi .
• Kubalulekile ukufuna iingcebiso zonyango ukuba uneempawu ezifana namaqhubu entamo, utshintsho kwilizwi, okanye ubunzima bokuginya.
• Kufuneka i-biopsy ukuze kuqinisekiswe ukuba lo ngumhlaza okanye akunjalo.
• Unyango oluphambili kukususwa kwe-thyroid gland ngotyando .
• Emva kotyando, kusenokufuneka usele iipilisi zehomoni ye-thyroid ubomi bakho bonke .
• Kukho ithuba lokuba umhlaza uza kuphinda ubuye, ngoko ke kufuneka ukwazi oko .
• Iqela lakho lezonyango lihlala likulungele ukukuxhasa .

Ndiyathemba ukuba olu lwazi luza kukunceda. Ukuba unemibuzo okanye iinkxalabo, nceda ungathandabuzi ukuthetha nogqirha wakho.

I- Hürthle Cell Carcinoma, Umhlaza weThyroid, Ii-Tumors zeNtlalo, Utyando lweThyroid, Iimpawu zoMhlaza, Unyango loMhlaza, I-Hürthle Cell Carcinoma