Ngaba ngequbuliso ukhe waba nehlwili legazi, okanye waba nengxaki ethile ngexesha lokukhulelwa waza ugqirha wenza uvavanyo lwegazi? Ngaba ukhathazekile xa ingxelo ithi 'Lupus Anticoagulant positive'? Ngaba woyika xa ubona igama elithi 'lupus' waza wacinga ukuba le yilupus? Eli gama liyadida. Yiyo loo nto abantu abaninzi bengaqondi kakuhle ngalo. Masilungise zonke iingxaki malunga noku namhlanje.
Yintoni kanye kanye iLupus Anticoagulant?
Ngamafutshane, olu luhlobo lwe-antibody olunokubakho egazini lethu.
Cinga ngenkqubo yomzimba yethu yokuzikhusela njengomkhosi okhusela ilizwe. Xa intsholongwane okanye into eyingozi ingena emzimbeni isuka ngaphandle, lo mkhosi uyayiqonda loo ntshaba uze udale iqela lamajoni akhethekileyo, abizwa ngokuba zii-antibodies, ukuze ayitshabalalise. Oku kudla ngokwenzeka.
Kodwa, ngamanye amaxesha inkqubo yethu yomzimba yokuzikhusela iyaphazama. Endaweni yokuhlasela abahlaseli bamanye amazwe, iqala ukuhlasela iiseli zethu eziphilileyo . Yiyo loo nto i-lupus anticoagulant (LA) iyi-antibody eveliswa ngempazamo kwaye yonakalisa imizimba yethu.
Le antibody ye-LA, kunye nezinye ii-antibodies ezimbini, inokubangela imeko ebizwa ngokuba yi -Antiphospholipid Syndrome (APS) . Esi sisifo esibangelwa kukuzimela komzimba. Uphawu oluphambili lwale nto kukuba umngcipheko wokwakheka kwamahlwili egazi kwimithambo yegazi yomzimba uphezulu kakhulu kunomntu oqhelekileyo.
Kutheni ke oku kubizwa ngokuba yi-'lupus'? Ngaba esi sisifo esifanayo ne-lupus?
Kulapho abantu abaninzi badideka khona baze boyike. Nangona kukho inxalenye 'ye-lupus' egameni, i-lupus zizinto ezimbini ezahlukeneyo: i-Lupus Anti-Coagulant (LA) kunye nesifo se-Lupus. Libali elinomdla kakhulu indlela eli gama elivela ngayo.
Le antibody yafunyanwa okokuqala kwiminyaka emininzi eyadlulayo xa abaphandi babevavanya iisampuli zegazi kubantu abanesifo se-lupus. Ngoko ke babecinga ukuba yinto ethile kubantu abanesifo se-lupus.
Bakwaqaphele ukuba iisampuli zegazi eziqulathe le antibody zithatha ixesha elide kunesiqhelo ukuze zijijeke kwi-vitro. Igama elithi 'Anticoagulant' lithetha 'ukuthintela ukujija kwegazi.' Ngoko ke, balibiza ngokuba yi-'lupus anticoagulant', elithetha 'into ethile emzimbeni wabantu abane-lupus ethintela ukujija kwegazi.'
Nangona kunjalo, ezo ngcinga zombini kamva zafunyaniswa zingalunganga. Enyanisweni, okuchaseneyo noko kuyinyani. Oko kwenziwa yile antibody ngaphakathi emzimbeni kukwandisa ukujiya kwegazi, kungekhona ukuthintela oko!
Ukuze ulungise le ngxaki, jonga le theyibhile ingezantsi.
| Inyani | I-Lupus anticoagulant (LA) | Isifo seLupus (SLE) |
|---|---|---|
| Indalo | I-antibody ethile eyingozi egazini. | Isifo esintsonkothileyo sokuzikhusela komzimba esichaphazela amalungu ahlukeneyo emzimbeni. |
| Isiphumo esiphambili | Iyandisa umngcipheko wokuqhekeka kwegazi. | Iinkqubo ezininzi zinokuchaphazeleka, njengolusu, amalungu, izintso, intliziyo, kunye nengqondo. |
| Ulwalamano | Ukuba ne-LA akuthethi ukuba une-lupus, kodwa abanye abantu abane-lupus banokuba ne-LA. | I-LA yenye yezinto ezifunyenweyo ezinokunxulunyaniswa ne-lupus. |
Kutheni into enje isenzeka emizimbeni yethu?
Oku kungenxa yokuba inkqubo yethu yomzimba yokuzikhusela yenza impazamo. Ezi antibodies ze-LA zihlasela iiproteni ezinamathele kuhlobo oluthile lwezinto ezinamafutha ezibizwa ngokuba yi-phospholipids kumphezulu wangaphandle weeseli zethu. Olu hlaselo lonakalisa iiseli, lubangela ukuba zinamathele kunye kwaye lonyuse umngcipheko wokuqhekeka kwegazi.
Iingcali azikaqiniseki ngokupheleleyo ukuba kutheni inkqubo yomzimba yokuzikhusela iqala ukwenza la ma-antibodies aneempazamo kwasekuqaleni. Zikholelwa ukuba oku kusenokuba kungenxa yezizathu zemfuza, iimpembelelo zokusingqongileyo, okanye ezinye iimeko ezisulelayo.
Ithetha ukuthini i-LA positive? Iza kundichaphazela njani?
Ukuba ne-LA egazini lakho kuthetha ukuba usemngciphekweni wokufumana imeko ebizwa ngokuba yi-antiphospholipid syndrome (APS). Apha, 'usemngciphekweni'Igama elithi "intando" libaluleke kakhulu. Alithethi ukuba ngokuqinisekileyo liza kwenzeka.
Nangona i-antibody ye-LA ikhona egazini, baninzi abantu abahlala besempilweni ubomi babo bonke ngaphandle kokufumana amahlwili egazi okanye iingxaki.
Ngoko ke ungoyiki ngokungeyomfuneko xa ubona oku kwingxelo yakho. Nangona kunjalo, kubalulekile ukuba ugqirha wakho akuqaphele oku aze akubeke esweni. Ekubeni unamathuba amaninzi okuba namahlwili egazi kunabanye, kulungile ukukuqonda oko.
Zithini iindlela zonyango zoku?
Akukho nyango okwangoku olususa ngokupheleleyo le antibody ye-LA emzimbeni. Kodwa kukho unyango oluhle kakhulu lokulawula umonakalo olunokuwubangela, oko kukuthi ukwakheka kwamahlwili egazi.
Ukuba awunazo iimpawu, oko kuthetha ukuba awuzange ube nehlwili legazi ngaphambili, ugqirha wakho unokugqiba ekubeni akujonge ngaphandle kokukunika amayeza.
Nangona kunjalo, ukuba ukhe waba negazi eliqhekekileyo ngaphambili okanye ufunyaniswe une-APS, unyango oluphambili zii -anticoagulants okanye ii-blood thinners . Amayeza afana ne-warfarin kunye ne-heparin anikwa ukunciphisa umngcipheko wegazi eliqhekekileyo. Ngamanye amaxesha, amayeza afana ne -corticosteroids nawo anikwa ukunciphisa ukusebenza ngokugqithisileyo kwenkqubo yomzimba yokuzikhusela.
Zonke ezi ndlela zonyango zigqitywa ngugqirha wakho, kuthathelwa ingqalelo izinto ezininzi ezifana nemeko yakho, ubudala, kunye nezinye izifo.
Ndifanele ndimbone nini ugqirha? Yintoni imeko engxamisekileyo?
Xa uphila nale meko, kubaluleke kakhulu ukwazi umahluko phakathi kweemeko eziqhelekileyo kunye nezingxamisekileyo.
| Amathuba | Kwenziwe ntoni |
|---|---|
| Ukuqwalaselwa ngokubanzi | Yiya ekliniki ngexesha elibekiweyo ukuze uhlolwe njengoko ugqirha esitsho. Baza kwenza uvavanyo lwegazi ukuze babone ukuba idosi yamayeza ichanekile na kwaye kukho naluphi na olunye utshintsho olukhoyo. |
| Ingxamiseko (yiya kwi-ETU ngoko nangoko) |
|
Iimpawu ezilumkisayo zokuqhekeka kwegazi
- Umlenze (Deep Vein Thrombosis - DVT): Ukudumba ngequbuliso, ukuba bomvu, ukufudumala, kunye nentlungu emlenzeni omnye.
- Ukuphefumla okungapheliyo: Ukuphelelwa ngumoya ngequbuliso, iintlungu ezibukhali esifubeni (ingakumbi xa uphefumla), ukukhohlela igazi.
- Istroke: ukugoba kwelinye icala lobuso, ukuphelelwa yingalo, ubunzima bokuthetha.
Ukuba kukho naziphi na kwezi mpawu, yiya kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele ngaphandle kokulibazisa .
Umyalezo Wokuya Ekhaya
- I-Lupus anticoagulant (LA) ayisiyo i-lupus ngokwayo. Luhlobo nje lwe-antibody egazini.
- Ukuba ne-LA egazini lakho kuthetha ukuba usengozini enkulu yokuba nehlwili legazi. Oko akuthethi ukuba kuya kwenzeka ngokuqinisekileyo.
- Musa ukoyika emva kokubona ingxelo. Kodwa ngokuqinisekileyo thetha nogqirha wakho ngale nto uze ulandele icebiso lakhe.
- Injongo ephambili yonyango kukuthintela ukwakheka kwamahlwili egazi. Ugqirha wakho uya kukumisela eyona ndlela ilungileyo yonyango.
- Hlala uqaphela iimpawu ezilumkisayo zokuqhekeka kwegazi (ukudumba kwemilenze, iintlungu zesifuba, ubunzima bokuphefumla). Ukuba kuvela uphawu olunjalo, yiya kwi-ETU ngoko nangoko.
- Kuqhelekile ukuziva usoyika kwaye uxhalabile xa ucinga ukuba into ongayiboniyo emzimbeni wakho inokukwenzakalisa. Endaweni yokuhlala uloyiko, phila ngokuqonda nangokulumka. Ugqirha wakho angakunceda kolo hambo.
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