Ukuqhinwa ngenxa yee-opioids? Nantsi isisombululo: Funda ngenaliti ye-methylnaltrexone!

Ngamanye amaxesha, xa sithatha amayeza okudambisa iintlungu anamandla, okanye ii-opioids, ezinikwe ngoogqirha ngenxa yengxaki enkulu, emva kotyando, okanye ngenxa yentlungu eqhubekayo, sigqibela sinengxaki eyahlukileyo, akunjalo? Oko kukuqunjelwa . Kwabanye abantu, oku kuyacaphukisa kangangokuba abakwazi nokutya okanye ukusela. Ngoko ke namhlanje siza kuthetha ngenaliti ekhethekileyo enceda ekuqunjelweni okubangelwa zii-opioids. Elo liyeza elibizwa ngokuba yi-methylnaltrexone.

Yintoni le yeza ibizwa ngokuba yi-methylnaltrexone? Isebenza njani?

Ngoku makhe sijonge ukuba yintoni kanye kanye le medication ebizwa ngokuba yi-methylnaltrexone kwaye ingakunceda njani. Ngamafutshane, yenzelwe ngokukodwa ukunyanga ukuqhina okubangelwa zii-opioid ozisebenzisayo xa usenza iintlungu.

Cinga ngayo, ii-opioid ozisebenzisayo zinokunciphisa iintlungu ngokwenene. Yiyo loo nto. Kodwa zikwanciphisa ukuhamba kwamathumbu akho, zenza amathumbu akho abe 'nobuvila' kancinci. Isantya esihamba ngaso indle emathunjini akho siyancipha. Kulapho ukuhamba kwamathumbu kuye kulibaziseke, ngamanye amaxesha kuhlale iintsuku, okanye kube nzima kakhulu.

Ngoko ke, eli yeza le-methylnaltrexone lenza into emangalisayo ngokwenene. Lithintela imiphumo yezo opioid emathunjini akho, nto leyo ethintela amathumbu ukuba angasebenzi. Kodwa, eyona nto ibalulekileyo kukuba, aliyi engqondweni yakho ukuze linciphise iintlungu. Lisebenza ngqo emathunjini akho. Emva koko izihlunu emathunjini akho ziqala ukusebenza kakuhle kwakhona, zikuncede uphume endle. Udla ngokubona iziphumo kwisithuba sesiqingatha seyure. Olu hlobo lweyeza silubiza ngokuba 'yi-opioid blocker' . Oko kukuthi, lithintela ezinye zezenzo ze-opioids, ingakumbi impembelelo yazo emathunjini.

Eli yeza ngamanye amaxesha linokumiselwa ngoogqirha kwezinye iimeko, ngoko ke ukuba unemibuzo, buza ugqirha wakho okanye ingcali yezemithi. Eli yeza likwaphantsi kwegama lophawu elithi `(Relistor)`.

Zeziphi izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba usebenzise eli yeza?

Ngaphambi kokuba uqale ukusebenzisa i-methylnaltrexone, kubalulekile ukunika ugqirha wakho inkcazo epheleleyo yempilo yakho. Oku kungenxa yokuba kulapho kuphela apho unokugqiba khona ukuba eli yeza likulungele na. Nazi ezinye izinto ekufuneka uzazi ngokuqinisekileyo:

• Ukuba unesifo sezintso . Ngenxa yokuba amayeza amaninzi asuswa emzimbeni ngezintso, ukuba unengxaki yezintso, kufuneka ucinge ngononophelo malunga nomthamo weyeza.
• Ukuba unesifo sesibindi , isibindi sikwalilungu eliphambili elihlambulula imizimba yethu ngamayeza. Ngoko ke ukuba kukho ingxaki yesibindi, naleyo kufuneka ikhankanywe.
• Kukho into engalunganga ngesisu okanye emathunjini akho?Ukuba ikhona. Umzekelo, ukuba kukho ukuvaleka kwamathumbu, isilonda, okanye enye imeko enzulu. Ngenxa yokuba eli yeza landisa umsebenzi wamathumbu, lisenokungafaneleki kubantu abanezi meko.
• Ukuba ukhe waba ne-allergy kwi-methylnaltrexone, naluphi na olunye unyango, ukutya, iidayi, okanye izithinteli.
• Ukuba ukhulelwe okanye uzama ukukhulelwa, kubalulekile ukuthetha nogqirha wakho ngaphambi kokuba uthathe naliphi na iyeza ngeli xesha.
• Ukuba ungumama oncancisayo, kufuneka uqaphele ukuba amanye amayeza anokudluliselwa kumntwana wakho ngobisi lwebele.

Akupheleli nje kwezi zinto, kodwa kubaluleke kakhulu ukuxelela ugqirha wakho ngazo naziphi na iingxaki zempilo onazo kunye nezinye iziyobisi ozisebenzisayo.

Ndingayisebenzisa njani le yeza? Yeyiphi indlela engcono?

Eli yeza, elibizwa ngokuba yi-methylnaltrexone, linikwa njengenaliti phantsi kolusu . Lidla ngokunikezelwa esibhedlele okanye eklinikhi.

Nangona kunjalo, ngamanye amaxesha kusenokufuneka uzinike le naliti ekhaya. Ukuba oko kuyenzeka, ungakhathazeki. Ugqirha okanye umongikazi wakho uza kukufundisa ngqo indlela yokuyilungisa, indlela yokuyifaka phantsi kolusu lwakho, kunye nendlela yokuyenza ngokucocekileyo. Kufuneka ukwenze kanye njengoko bekuxelela, ngokulandelelana okufanayo. Akulunganga ukuyithatha kaninzi okanye ngaphezulu kunokuba ugqirha ekuxelela.

Eyona nto ibalulekileyo kukuba, akufanele na ubeke iinaliti zakho ezisetyenzisiweyo kunye neesirinji emgqomeni wenkunkuma? Kukho isitya esikhethekileyo see-sharps . Ungayicela kwikhemesti yakho okanye kugqirha. Kulapho kufuneka ubeke khona ezi zinto zisetyenzisiweyo. Oku kungenxa yokhuseleko lwethu sonke kunye nokuphepha ukubeka abanye emngciphekweni.

Xa unikwa eli yeza, ikhemesti iya kukunika incwadana yolwazi ekhethekileyo ebizwa ngokuba yi-"MedGuide" . Eli linikwa ngalo lonke ixesha xa ufumana iyeza elitsha, nokuba sele ulizalisile. Liqulethe ulwazi oluninzi olubalulekileyo malunga neyeza. Kungoko ke, kubaluleke kakhulu ukulifunda ngononophelo.

Kufuneka kuthathelwe ingqalelo ekhethekileyo xa kunikwa abantwana eli yeza . Ngoko ke, ukuba ufuna ukunika umntwana wakho eli yeza, thetha nogqirha wakho ngalo ngononophelo kwaye ulandele imiyalelo yakhe.

Yintoni omawuyenze ukuba uthatha amayeza amaninzi kakhulu? (Ukusebenzisa amayeza amaninzi kakhulu)

Ukuba ucinga ukuba usele kakhulu eli yeza, fowunela iziko lolawulo lwetyhefu elikufutshane nawe okanye igumbi likaxakeka ngokukhawuleza. Kungenjalo, yiya ngoko nangoko.

Khumbula, eli yeza lelakho wedwa. Ungaze wabelane ngeli yeza nabanye.

Kuthekani ukuba ndiphoswa yidosi?

Eli asiloyeza elidla ngokuthathwa ngexesha elifanayo yonke imihla. Oko kukuthi, asiloyeza elisetyenziswa rhoqo. Linikwa xa kufuneka. Ngoko ke, akukho mfuneko yokukhathazeka malunga nokuphoswa lithuba lokufumana amayeza. Nangona kunjalo, ukuba unemibuzo malunga nendlela ugqirha wakho akuxelele ngayo ukuba uwasebenzise, ​​buza.

Zeziphi ezinye izinto ezinokusebenzisana nale mithi? (Iindlela ezisetyenziswa ngayo)

Kukho amayeza anokubangela iingxaki xa esetyenziswa nge-methylnaltrexone. Umzekelo:

• I-Alvimopan
• I-Naloxone
• I-Naltrexone

Olu luhlu aluphelelanga. Kusenokubakho amanye amayeza. Ngoko ke, xelela ugqirha wakho ngawo onke amayeza owathathayo (nokuba amiselwe ngabanye oogqirha okanye athengwe kwikhemesti), iimveliso zemifuno, iivithamini, kunye nezongezo zokutya ozisebenzisayo. Kwakhona, qiniseka ukuba uxelela ugqirha wakho ukuba uyatshaya, usela utywala, okanye usebenzisa ezinye iziyobisi ezingekho mthethweni. Ezinye izinto zinokudibana nalo mayeza kwaye zibangele iingxaki.

Yintoni esifanele siyilumkele ngakumbi xa sithatha eli yeza?

Kukho izinto ezimbalwa ekufuneka uzilumkele xa usebenzisa eli yeza:

• Emva kokusebenzisa eli chiza, hlala kwindawo onokuya kuyo kwindlu yangasese ngokukhawuleza. Kusenokufuneka ukhuphe indle emva nje kokusebenzisa eli yeza. Ngamanye amaxesha linokuba ngequbuliso.
• Ngelixa usela eli yeza, iqela lakho lezonyango liza kujonga imeko yakho ngokusondeleyo. Ukuba iimpawu zakho aziphucuki, okanye ukuba ziya zisiba mandundu, xelela ugqirha wakho okanye umongikazi wakho ngoko nangoko.
• Usenokuziva ulele okanye unesizungu emva kokusela eli yeza. Ngoko ke, de wazi kakuhle indlela eli yeza elikuchaphazela ngayo, kuphephe ukuqhuba, ukusebenzisa oomatshini, okanye ukwenza nantoni na efuna ukuqwalaselo.
• Musa ukuma okanye ukuhlala ngequbuliso. Lumka ngakumbi ukuba umdala. Ukwenza njalo kunokukwenza uzive unesiyezi kwaye ungawa.
• Kuphephe ukusela utywala. Utywala bunokuphazamisa ukusebenza kakuhle kwale mithi.

Zithini iziphumo ebezingalindelekanga ezinokubakho zeli yeza? (Iziphumo ebezingalindelekanga)

Njengalo naliphi na iyeza, i-methylnaltrexone inokubangela ezinye iziphumo ebezingalindelekanga. Nangona kunjalo, ayinguye wonke umntu ozifumanayo. Ezinye ziyingozi, kwaye ezinye azibi yingozi kangako.

Iziphumo ebezingalindelekanga ekufuneka uzixele kugqirha wakho ngoko nangoko:

Ukuba ufumana naziphi na kwezi mpawu, xelela iqela lakho lezempilo ngokukhawuleza:

• Iimpendulo ze-allergy:Ukurhawuzelela kwesikhumba, ukurhawuzelela, iimpawu ezifana nokurhawuzelela, ukudumba kobuso, imilebe, ulwimi, nomqala. Ezi zinokuba yingozi kakhulu.
• Intlungu ebuhlungu esiswini: Oku kuthetha ukuba intlungu inzima kakhulu, ihlala ihleli, kwaye iyanda kunentlungu eqhelekileyo yesisu.

Iziphumo ebezingalindelekanga ezihlala zingadingi ngcebiso kagqirha, kodwa kufuneka zixelwe kugqirha wakho ukuba ziyaqhubeka okanye ziyakhathaza:

Ezi zifo zihlala ziphela emva kweentsuku ezimbalwa. Nangona kunjalo, ukuba ziyaqhubeka kwaye zikukhathaza, xelela ugqirha wakho:

• Ukuziva ubanda (Ukugodola)
• Urhudo
• Ukubila okugqithisileyo
• Intloko ebuhlungu
• Isicaphucaphu
• Intlungu yesisu (engachazwanga ngqo)

Olu luhlu alubandakanyi zonke iziphumo ebezingalindelekanga. Ukuba ubona nantoni na engekhoyo, thetha nogqirha wakho ngayo. Ungaxela iziphumo ebezingalindelekanga kwi-FDA ku-1-800-FDA-1088.

Ungaligcina njani eli yeza? (Ugcino)

Kubaluleke kakhulu ukugcina amayeza ngokufanelekileyo.

• Gcina eli yeza kude nabantwana kunye nezilwanyana zasekhaya.
• Gcina kubushushu begumbi (phakathi kwama-20 nama-25 degrees Celsius, phakathi kwama-68 nama-77 degrees Fahrenheit) . Musa ukugcina kwindawo ebanda kakhulu (njengakwifriji). Kwakhona, khusela ekukhanyeni.
• Musa ukusebenzisa amayeza aphelelwe lixesha. Walahle ngokufanelekileyo.

Le ncwadana sisishwankathelo nje. Isenokungabi nalo lonke ulwazi olufunayo. Ukuba unemibuzo engaphezulu malunga nale yeza, nceda uthethe nogqirha wakho, ikhemisti, okanye omnye umboneleli wezempilo.

Izinto ezibalulekileyo ekufuneka uzikhumbule (Umyalezo Wokuya Ekhaya)

Kulungile, ngoko ke, singakukhumbuza kwakhona ngezinto ezibalulekileyo ekufuneka uzikhumbule kwizinto esithethe ngazo?

1. I-Methylnaltrexone yinaliti ekhethekileyo enikwa ukuqhina okubangelwa zii-opioid (iipilisi zokunciphisa iintlungu).

2. Oku kusebenza kuphela emathunjini, akunampembelelo kwiyeza lokuthomalalisa iintlungu.

3. Qiniseka ukuba uxelela ugqirha wakho ngezinye izifo onazo kunye namayeza owasebenzisayo.

4. Sebenzisa inaliti kanye njengoko ugqirha wakho ekuxelele. Lahla iinaliti ezisetyenzisiweyo ngokukhuselekileyo.

5. Hlala kufutshane nendlu yangasese emva kokusebenzisa inaliti. Lumka xa kukho ukozela kunye nesiyezi, njengoko oku kunokwenzeka.

6. Ukuba uva iintlungu zesisu okanye i-allergy, xelela ugqirha wakho ngoko nangoko.

Ndiyathemba ukuba olu lwazi uza kulufumana luluncedo. Hlala usempilweni!

I- Methylnaltrexone, i-Methylnaltrexone, ukuqunjelwa yi-opioid, amayeza okuqunjelwa, i-Relistor, iziphumo ebezingalindelekanga zamayeza, inaliti