Ngaba ugqirha wakho ukunike wena okanye umntu kusapho lwakho iyeza elibizwa ngokuba yiMidostaurin? Usenokoyika kancinci xa usiva eli gama. Kodwa ungakhathazeki. Olu lunyango oluphambili kakhulu nolukhethekileyo olubulala iiseli zomhlaza. Ngoko ke kukho izinto ezibalulekileyo ekufuneka uzazi xa usebenzisa eli yeza. Masithethe ngayo yonke into ngendlela elula onokuyiqonda.
Yintoni le Midostaurin?
Ngamafutshane, olu luhlobo lonyango olubizwa ngokuba yi-'Targeted Therapy'. Oko kukuthi, aluzilimazi iiseli ezisempilweni njenge-chemotherapy eqhelekileyo, kodwa lujolise ngqo kwiiproteni ezithile kwiiseli zomhlaza kwaye luthintele ezo seli ukuba zingakhuli. Ngamanye amazwi, kufana nokuchonga utshaba kunye nokuhlasela zona kuphela.
Eli yeza lisetyenziswa kakhulu ukunyanga ezi meko zilandelayo:
- I-Acute Myelogenous Leukemia (AML): Olu luhlobo lomhlaza oluvela egazini.
- I-Systemic Mastocytosis: Le yimeko apho uhlobo lweseli olubizwa ngokuba yi-'mast' lukhula ngokungeyomfuneko emzimbeni.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale amayeza
Ngaphambi kokuba uqale ukusebenzisa eli yeza, ngokuqinisekileyo kufuneka uxelele ugqirha wakho ngezi zinto, kuba zibaluleke kakhulu kukhuseleko lwakho.
- Ukuba uneengxaki zemiphunga okanye zokuphefumla.
- Ukuba une-allergies kule Midostaurin okanye naliphi na elinye iyeza, ukutya, okanye idayi.
- Ukuba ukhulelwe, uzama ukukhulelwa , okanye unamathandabuzo ngaloo nto.
- Ukuba uncancisa umntwana.
Ukuthetha nogqirha wakho ngezi zinto ngaphandle kokuzifihla kuya kunceda kakhulu ukuba unyango lwakho luphumelele.
Ndingayisebenzisa njani kanye kanye le yeza?
Eyona ndlela ikuphela kwayo yokufumana okuninzi kwiyeza kukulisebenzisa ngokuchanekileyo.
- Sela eli yeza neglasi yamanzi.
- Qiniseka ukuba usela eli yeza xa usitya. Musa ukulisela ungenanto esiswini.
- Musa ukulisebenzisa eli yeza kunye nejusi yegrapefruit nangasiphi na isizathu, kuba linokuwenza ngcono umsebenzi walo ngokungeyomfuneko kwaye libangele iziphumo ebezingalindelekanga ezibi kakhulu.
- Musa ukuhlafuna iyeza njengetshungama. Liginye lonke.
- Sela amayeza malunga nexesha elifanayo yonke imihla.
- Musa ukuyeka ukuthatha amayeza akho ngaphandle kwengcebiso kagqirha wakho.
- Ukuba uphoswe yidosi okanye uhlanza emva kokusela iyeza, yiyeke loo dosi. Ungaze uthathe idosi ephindwe kabini. Thatha idosi elandelayo ngexesha elicwangcisiweyo.
Kuthekani ukuba ndisebenzisa i-overdose?
Ukuba ucinga ukuba usele kakhulu eli yeza, ungoyiki kwaye ngoko nangoko fowunela iZiko loLwazi lweePoison kwiSibhedlele sikaZwelonke saseColombo . Okanye yiya kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.
Amanye amayeza anokusebenzisana nalo mayeza (Ukusebenzisana kwamayeza)
Ngenxa yokuba iMidostaurin liyeza elinamandla kakhulu, linokusebenzisana namanye amayeza owasebenzisayo. Ngoko ke, kufuneka wazise ugqirha wakho ngawo onke amayeza owasebenzisayo, kuquka amayeza abhalwe ngugqirha, amayeza athengiswa ngaphandle kwemvume kagqirha, iimveliso zezityalo, kwaneevithamini.
La mayeza alandelayo angabangela iingxaki ezithile ngale nto.
| Udidi lwamayeza olunokubangela iingxaki | Imizekelo (ayiphelelanga kwezi) |
|---|---|
| Amayeza angafanele asetyenziswe kunye | i-cisapride, i-dronedarone, i-fluconazole, i-pimozide, i-posaconazole, i-saquinavir, i-thioridazine |
| Amanye amayeza e-HIV okanye i-AIDS | Amayeza afana ne-boceprevir, ritonavir, indinavir, nelfinavir |
| Amanye amayeza osulelo lwefungus | i-ketoconazole, i-itraconazole, i-voriconazole |
| Amanye amayeza okunyanga isifo sokuwa | i-carbamazepine, i-phenytoin |
| Okunye | i-bupropion, i-clarithromycin, i-diltiazem, i-rifampin, i-rosuvastatin, i-St. John's Wort (isicatshulwa semifuno) |
Izinto ekufuneka uzikhumbule xa usebenzisa amayeza
Uvavanyo lwegazi oluqhelekileyo
Ugqirha wakho uhlala eyalela uvavanyo lwegazi xa ekunika eli yeza. Oku kuya kukunceda ubone indlela elichaphazela ngayo umzimba wakho kunye nokuba kukho naziphi na iziphumo ebezingalindelekanga.
Lumka kwiintsholongwane.
Inkqubo yakho yomzimba yokuzikhusela isenokuba buthathaka kancinci ngelixa usebenzisa eli yeza, nto leyo eyonyusa umngcipheko wakho wokufumana usulelo.
- Ukuba ubonakalisa iimpawu ezinje ngomkhuhlane, ukubanda, umphimbo obuhlungu, kunye nokukhwehlela , musa ukuzinyanga kwaye utsalele umnxeba ugqirha wakho.
- Zama ukuhlala kude nabantu abagulayo.
- Hlamba izandla zakho kakuhle rhoqo.
Lumka ukopha.
Ukuba ufumana amanxeba naphi na emzimbeni wakho, okanye ukuba ukopha akupheli nokuba kungenzakalanga okuncinci, yazisa ugqirha wakho ngoko nangoko.
Ukukhulelwa kunye nokuncancisa
Oku kubaluleke kakhulu. Abafazi kufuneka bakuphephe ngokupheleleyo ukukhulelwa ngelixa besebenzisa eli yeza kwaye kangangeenyanga ezi-4 emva kokuyeka eli yeza . Ngokufanayo, amadoda kufuneka akuphephe ukuba nguyise womntwana ngelixa ethatha eli yeza kwaye kangangeenyanga ezi-4 emva kokuyeka eli yeza . Oku kungenxa yokuba kukho umngcipheko omkhulu wokwenzakalisa umntwana ongakazalwa.
Kwakhona, musa ukuncancisa umntwana wakho ngelixa usebenzisa amayeza kwaye kangangeenyanga ezi-4 emva kokuba uyekile .
Zeziphi iziphumo ebezingalindelekanga endinokuzifumana?
Njengayo nayiphi na iyeza, oku kunokubangela iziphumo ebezingalindelekanga. Nangona kungengabo bonke abantu abazifumanayo, lumka ezi mpawu zingasentla.
| Ukuba unayo nayiphi na kwezi, yazisa ugqirha wakho ngokukhawuleza. | |
|---|---|
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi, ubunzima bokuphefumla. |
| Utshintsho kwisantya sentliziyo | Intlungu yesifuba, isiyezi, ukubetha kwentliziyo ngokukhawuleza okanye ngokungangqalanga. |
| Amanqanaba eswekile egazini anyukileyo | Indlala egqithisileyo, ukoma okugqithisileyo, ukuchama rhoqo, ukubona okufipheleyo. |
| Iimpawu zosulelo | Umkhuhlane, ukubanda, ukukhohlela, umphimbo obuhlungu. |
| Ukuncipha kweeseli ezibomvu zegazi | Ubunzima bokuphefumla, ukuquleka, ukudinwa kakhulu. |
| Ezinye iimpawu ezinzulu | Ukudumba kwamaqatha, iinyawo, izandla, ukopha okungaqhelekanga okanye ukukrweleka. |
| Ukuba ezi zinto ziyaqhubeka okanye ziyakukhathaza, yazisa ugqirha wakho. | |
Intlungu yamathambo, ukuqhina, urhudo, intloko ebuhlungu, izilonda zomlomo, iintlungu zemisipha, isicaphucaphu, iintlungu zesisu, ukuhlanza. | |
Umyalezo Wokuya Ekhaya
- I-Midostaurin liyeza lonyango elijoliswe kwiiseli zomhlaza.
- Eli yeza lifanele lisetyenziswe rhoqo kunye nokutya. Ungaze ulisebenzise kunye nejusi yegrapefruit.
- Xelela ugqirha wakho ngazo zonke ezinye iziyobisi ozisebenzisayo.
- Ukuba ufumana iimpawu ezingaqhelekanga ezifana nomkhuhlane okanye ukopha, funa ingcebiso kagqirha ngoko nangoko.
- Kuphephe ukukhulelwa (nababini ngokwesini) ngelixa usela amayeza kwaye emva kweenyanga ezi-4 uyekile.
- Gcina eli yeza kwibhotile yalo yokuqala, evalwe kakuhle, kubushushu begumbi, kude nabantwana nezilwanyana zasekhaya.
- Ukuba unemibuzo malunga nale yeza, ungoyiki ukubuza ugqirha wakho.
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