Ngaba wena okanye umntu osapho lwakho unyangelwa umhlaza webele? Ngoko ke kusenokwenzeka ukuba ukhe weva ngeyeza elithi 'Neratinib'. Mhlawumbi ugqirha wakho ukuxelele ukuba uqale ukulisebenzisa eli yeza. Eli liyeza elibaluleke kakhulu elibulala iiseli zomhlaza. Ngoko ke, ukuze siphendule nayiphi na imibuzo okanye uloyiko malunga neli yeza, masithethe ngalo ngendlela elula onokuyiqonda.
Ngamafutshane, yintoni iNeratinib?
I-Neratinib luhlobo lweyeza elijolise kwiiproteni ezithile kwiiseli zomhlaza kwaye lizithintele ekukhuleni kwazo. Ngokuchanekileyo, isebenza "njengonyango olujoliswe kulo." Isetyenziswa kakhulu ukunyanga umhlaza webele. Eli yeza lifumaneka kwimarike phantsi kwegama lebrendi elithi Nerlynx .
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale amayeza
Ngaphambi kokuba ugqirha wakho akunike eli yeza, kuya kufuneka abe nomfanekiso opheleleyo wempilo yakho. Ngoko ke, ukuba unenye yezi meko zilandelayo, qiniseka ukuba uxelela ugqirha wakho ngazo.
- Isifo Sesibindi: Oku kubaluleke kakhulu ukuba unesifo sesibindi, njengoko eli yeza lingayichaphazela indlela esebenza ngayo isibindi sakho ukuze lisisuse emzimbeni wakho.
- Ukuphelelwa ngamanzi emzimbeni: Ukuba unengxaki yokunqongophala kwamanzi emzimbeni wakho kwaye uphelelwe ngamanzi emzimbeni, nceda usixelele ngayo.
- Ukuba uzama ukukhulelwa okanye ukhulelwe: Oku kubaluleke kakhulu. Kufuneka ukuphephe ukukhulelwa ngelixa usebenzisa eli yeza.
- Ukuba ungumama oncancisayo: Akucetyiswa ukuba uncancise umntwana wakho ngelixa usebenzisa eli yeza.
- Ezinye ii-Allergies: Xelela ugqirha wakho ukuba unayo nayiphi na i-allergies kwi-neratinib okanye naliphi na elinye iyeza, ukutya, okanye idayi.
Ndingayisebenzisa njani le yeza?
Kubaluleke kakhulu ukusela amayeza akho kanye njengoko ugqirha wakho ekuxelele. Nazi ezinye iingcebiso eziqhelekileyo onokuzilandela.
- Ginya le pilisi yonke ngeglasi yamanzi .
- Musa ukuphula, ukutyumza, okanye ukuhlafuna ithebhulethi.
- Sela iyeza xa usitya . Oku kunokunciphisa ukungonwabi esiswini.
- Ziqhelise ukusela amayeza akho ngexesha elifanayo yonke imihla.
- Musa ukulisebenzisa eli yeza kunye nejusi yegrapefruit . Linokuchaphazela ukusebenza kakuhle kweli yeza.
- Ukuba uthatha i-antacid (ulwelo okanye ithebhulethi yezilonda zesisu), ungayithathi kwiiyure ezi-3 ngaphambi okanye emva kokuthatha iNeratinib.
- Musa ukuyeka ukuthatha amayeza akho ngaphandle kwengcebiso kagqirha wakho.
Kuthekani ukuba ndiphoswa lidosi leyeza?
Ukuba ulibele ukuthatha idosi, yiyeke. Thatha idosi elandelayo ngexesha eliqhelekileyo. Ungaze uthathe iipilisi ezimbini zokubuyisela idosi ephosiweyo.
Kuthekani ukuba ndithatha amayeza amaninzi kakhulu?
Ukuba ukrokrela ukuba uthathe amayeza amaninzi kakhulu, ungoyiki kwaye ngoko nangoko fowunela iZiko loLwazi lweePoison kwiSibhedlele sikaZwelonke saseColombo . Okanye yiya kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.
Ezinye izinto ezinokusebenzisana nale mithi (Intsebenziswano)
Le yindawo apho kufuneka ulumke kancinci. I-Neratinib inokudibana namanye amayeza, ukutya, kunye nemifuno. Oku kuthetha ukuba ukuyithatha kunye nezi zinto kunokunciphisa okanye kwandise ukusebenza kwe-Neratinib, okanye kwandise iziphumo ebezingalindelekanga.
Ngoko ke, kufuneka uxelele ugqirha wakho malunga nawo onke amayeza, iivithamini, imifuno, kunye nezongezo ozithathayo, kunye nokuba uyatshaya okanye uyasela utywala.
Eli yeza linokuchaphazela oku kulandelayo ngokukodwa:
- Amanye amayeza okulwa neentsholongwane ze-HIV okanye i-AIDS
- Amayeza osulelo lwefungus (umz. i-ketoconazole, i-itraconazole)
- Amanye amayeza okubulala iintsholongwane (umz. i-clarithromycin, i-erythromycin)
- Amayeza okuxhuzula (umz. i-carbamazepine, i-phenytoin)
- Amayeza anciphisa i-asidi yesisu (umz. i-omeprazole, i-famotidine, i-lansoprazole)
- Amayeza esintu afana neSt. John's Wort
- Isiqhamo segrapefruit (iJambola)
Olu luhlu aluphelelanga, ngoko ke kungcono ukuxelela ugqirha wakho ngayo yonke into oyithathayo.
Amanqaku akhethekileyo ekufuneka uwaqaphele xa usebenzisa amayeza
Ukukhulelwa kunye nokuncancisa
Oku kubaluleke kakhulu.
- Abafazi: Kuphephe ukukhulelwa ngelixa usebenzisa la mayeza kwaye emva kwenyanga enye uyekile ukusebenzisa la mayeza. Thetha nogqirha wakho malunga nolawulo lokuzala olufanelekileyo.
- Amadoda: Ukuba usebenzisa eli yeza, qiniseka ukuba iqabane lakho alikhulelwa ngelixa ulisebenzisa eli yeza kwaye emva kweenyanga ezi-3 uliyekile.
- Musa ukuncancisa umntwana wakho ngelixa usebenzisa eli yeza kwaye inyanga enye emva kokuba uyekile.
Urhudo, ukuhlanza, kunye nokuphelelwa ngamanzi emzimbeni
Abanye abantu abasebenzisa i-neratinib banokufumana urhudo rhoqo. Ukuba unesifo sorhudo esinzima, ukuhlanza, okanye ukubila kakhulu, unokulahlekelwa lulwelo oluninzi emzimbeni wakho kwaye uphelelwe ngamanzi emzimbeni. Oku kunokuba yingozi, ngoko ke xelela ugqirha wakho ngoko nangoko.
Uvavanyo lwegazi
Ngelixa usebenzisa eli yeza, ugqirha wakho unokukucela ukuba wenze uvavanyo lwegazi rhoqo (umsebenzi wegazi) ukuze kujongwe izinto ezifana nokusebenza kwesibindi sakho.
Iziphumo ebezingalindelekanga ezinokubakho zale yeza
Njengalo naliphi na iyeza, iNeratinib inokubangela iziphumo ebezingalindelekanga. Ezinye ziyingozi, ngelixa ezinye zixhaphakile.
| Uhlobo lwesiphumo esibi | Iimpawu |
|---|---|
| Iziphumo ebezingalindelekanga ekufuneka zixelwe kugqirha ngoko nangoko | |
| Urhudo olukhulu okanye ukuhlanza | Urhudo oluqatha izihlandlo ezininzi ngemini, ukuhlanza okungenakuyekiswa. |
| Iimpawu zomonakalo wesibindi | Ukutyheli kwamehlo okanye ulusu, umchamo otyheli okanye omdaka omnyama, indle ekhanyayo, iintlungu kwicala eliphezulu lasekunene lesisu, ukungabi namdla wokutya, kunye nokudinwa kakhulu. |
| Iimpawu zoxinzelelo lwegazi oluphantsi | Ukuba nesiyezi, amehlo aluhlaza okwesibhakabhaka, ukuquleka, ukudinwa okungaqhelekanga. |
| Iimpawu zosulelo | Umkhuhlane okanye ukubanda, ukukhohlela, umphimbo obuhlungu, iintlungu xa uchama. |
| Ukuba iyaqhubeka okanye iyakhathaza, xelela ugqirha wakho. | |
| Iziphumo ebezingalindelekanga eziqhelekileyo | Umlomo owomileyo, ukungabi namdla wokutya, izilonda emlonyeni, ukuqaqamba kwemisipha, amabala abomvu eluswini, iintlungu zesisu, ukungonwabi esiswini, ukwehla kobunzima. |
Umyalezo Wokuya Ekhaya
- Soloko uthatha iipilisi zeNeratinib njengoko ugqirha wakho ekuyalele, ngexesha elimiselweyo, kunye nokutya.
- Xelela ugqirha wakho malunga namanye amayeza, iivithamini, imifuno, nazo zonke iimeko zakho zempilo.
- Kuphephe ukukhulelwa nokuncancisa ngokupheleleyo xa usebenzisa eli yeza kwaye kangangexesha elithile.
- Ukuba ufumana urhudo olukhulu, ukuhlanza, okanye iimpawu zokonakala kwesibindi (njengokuba tyheli kwesikhumba), tsalela umnxeba ugqirha wakho ngokukhawuleza.
- Eli yeza lelakho wedwa. Ungaze wabelane ngalo nabanye.
- Gcina amayeza akho kubushushu begumbi (phakathi kwama-20-25 degrees Celsius), kude nokufikelela kwabantwana.
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