Xa wena okanye umntu kusapho lwakho enikwa iyeza elitsha lokunyanga umhlaza, kuyinto eqhelekileyo ukuba novalo kwaye ube nomdla wokulifumana. Ingakumbi xa usiva ukuba libizwa ngokuba yi-"Chemotherapy." Kodwa i-Olaparib, esithetha ngayo namhlanje, ayifani namayeza esintu, kodwa liyeza eliphucukileyo elijolise ngqo kwaye linyange iiseli zomhlaza. Ngoko ke, ukuba ugqirha wakho uninike eli yeza, masithethe ngayo yonke into ekufuneka uyazi ngayo ngendlela elula neyobuhlobo.
Lithini eli yeza libizwa ngokuba yi-Olaparib?
Ngamafutshane, i-Olaparib liyeza elithintela ukukhula kweeseli zomhlaza. Imizimba yethu inee-enzymes ezikhethekileyo ezinceda iiseli ukuba zizilungise. Iiseli zomhlaza nazo zisebenzisa ezi enzymes ukulungisa umonakalo eziwenzayo kwaye ziqhubeke zikhula. I-Olaparib isebenza ngokuphazamisa le ndlela yokulungisa kwiiseli zomhlaza. Emva koko, iiseli zomhlaza azikwazi ukuzilungisa, kwaye ziyafa. Eli yeza lisebenza njenge "bhombu ekrelekrele" ehlasela kuphela ithagethi yotshaba.
Eli yeza lisetyenziswa kakhulu ukunyanga iintlobo ezithile zomhlaza, kuquka:
- Umhlaza wesibeleko
- Umhlaza webele
- Umhlaza wePancreatic
- Umhlaza weprostate
Eli yeza lisetyenziselwa ukunyanga izifo zomhlaza ezifana nezi:
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale amayeza
Ngaphambi kokuba uqalise eli yeza, ugqirha wakho kufuneka abe nomfanekiso opheleleyo wempilo yakho. Ke ngoko, ukuba unenye yezi meko zilandelayo, qiniseka ukuba uyamxelela ugqirha wakho ngazo. Ungazityesheli kuba zinokuba nefuthe elithe ngqo kunyango lwakho.
| Imeko yempilo okanye inyani | Kutheni ufanele uxelele ugqirha? |
|---|---|
| I-hemoglobin ephantsi egazini (i-anemia) | I-Olaparib inokunyusa ukopha ngakumbi, ngoko ke kufuneka kuthathwe ingqalelo. |
| Izifo zezintso, zesibindi, okanye zemiphunga | Ngenxa yokuba iziyobisi zisuswa emzimbeni ngezi zitho, kubalulekile ukwazi umsebenzi wazo. |
| Ukuncipha kweeseli zegazi (iiseli ezimhlophe zegazi, iiseli ezibomvu zegazi, iiplatelets) | Eli yeza linokunciphisa ngakumbi inani leeseli zegazi, ngoko ke kubalulekile ukukwazi oku ngaphambi kokuba uqale unyango. |
| Ukunganyamezelani ne-Olaparib okanye amanye amayeza, ukutya, okanye iidayi | Oku kubaluleke kakhulu ukuthintela ukusabela okunzulu kwe-allergy. |
| Ukuzama ukukhulelwa, ukukhulelwa, okanye ukuncancisa | Oku kubaluleke kakhulu kuba eli yeza linokulimaza umntwana osesiswini. |
Ndingayisebenzisa njani le mithi?
Kubaluleke kakhulu ukusebenzisa amayeza kanye njengoko ugqirha ewayalele.
- Ginya ipilisi ngeglasi yamanzi.
- Ungaze uyiqhekeze, uyityumze, okanye uyihlafune. Ginya yonke ipilisi.
- Ungalithatha eli yeza ngaphambi okanye emva kokutya. Nangona kunjalo, ukuba uziva uphazamisekile esiswini, kungcono ukulithatha kunye nokutya.
- Kubaluleke kakhulu: Musa ukutya okanye ukusela i-grapefruit okanye ijusi yeorenji yaseSeville ngelixa usebenzisa eli yeza. Oku kunokuchaphazela indlela elisebenza ngayo eli yeza.
- Sela amayeza akho ngamaxesha amiselweyo, njengoko kuyalelwe ngugqirha wakho. Musa ukuyeka ukuthatha amayeza akho okanye utshintshe umthamo ngaphandle kwengcebiso kagqirha wakho.
Inqaku Elibalulekileyo: Ukuba ukrokrela ukuba uthathe i-overdose, yiya kwiSebe lezeMpilo eziNgxamisekileyo (ETU) esibhedlele esikufutshane. Okanye utsalele umnxeba iZiko loLwazi lweePoison kwiSibhedlele sikaZwelonke saseColombo ukuze ufumane ingcebiso.
Yintoni omawuyenze ukuba uphoswe yidosi yeyeza?
Ukuba uphoswe yidosi, yithathe ngokukhawuleza xa ukhumbula. Nangona kunjalo, ukuba sele kuza kufuneka uyithathe idosi elandelayo, yitsibe idosi oyiphosileyo uze uthathe idosi elandelayo ngexesha elicwangcisiweyo. Ungaze uthathe iidosi ezimbini ngaxeshanye.
Ezinye izinto ezinokusebenzisana nale mithi (Intsebenziswano)
Amanye amayeza, iimveliso zezityalo, okanye ukutya okuthathayo kunokusebenzisana ne-Olaparib. Ngoko ke, kubaluleke kakhulu ukuxelela ugqirha wakho ngayo yonke into oyithathayo. Oku kuquka amayeza kagqirha, iivithamini, iimveliso zezityalo, kunye nezithomalalisi zentlungu.
Ngezantsi zezinye zezinto ezinokusebenzisana ne-Olaparib. Olu luhlu aluphelelanga.
- Amanye amayeza asetyenziswa kwizifo ezibangelwa yintsholongwane ezifana ne-HIV, i-AIDS, okanye i-Hepatitis
- Amanye amayeza asetyenziselwa usulelo lwefungus (umz. iKetoconazole, iFluconazole)
- Amanye amayeza okubulala iintsholongwane (umz. iClarithromycin, iErythromycin)
- Amanye amayeza okuxhuzula (umz. iCarbamazepine, iPhenytoin)
- Iimveliso zezityalo ezifana neSt. John's Wort
- Iigrapefruit kunye neeorenji zaseSeville
Izinto ekufuneka uzikhumbule xa usebenzisa amayeza
Xa unyangwa umhlaza, kuyinto eqhelekileyo ukuziva ungakhululekanga kwaye udiniwe, njengoko neeseli ezisempilweni nazo ziyachaphazeleka. Kodwa ungayeki unyango de ugqirha wakho akuxelele ukuba wenze njalo.
- Uvavanyo lwegazi: Ugqirha wakho uya kuyalela uvavanyo lwegazi rhoqo ukuze ajonge ukubalwa kweeseli zakho zegazi ngelixa usela eli yeza.
- Umngcipheko wokopha: Eli yeza linokunyusa umngcipheko wokukrweleka nokopha. Nokuba kukusikwa okuncinci kunokuthatha ixesha elide ukuyeka ukopha. Ukuba ubona nantoni na engaqhelekanga, efana nokopha kweentsini, ukopha kweempumlo, amabala abomvu phantsi kolusu, okanye indle emnyama, xelela ugqirha wakho ngoko nangoko.
- Umngcipheko wokosuleleka: Eli yeza linciphisa amandla omzimba okulwa nezifo (amasosha omzimba). Ngoko ke, zama ukuhlala kude nabantu abanomkhuhlane okanye umkhuhlane. Ukuba ubonakalisa iimpawu ezifana nomkhuhlane, ukubanda, okanye umphimbo obuhlungu, musa ukuzinyanga kwaye uthethe nogqirha wakho.
- Utyando: Ukuba utyando okanye ezinye iindlela zonyango, xelela ugqirha ukuba usebenzisa i-Olaparib.
Lumka ngakumbi ngexesha lokukhulelwa nokuncancisa!
Le yingongoma ebaluleke kakhulu.
- Abafazi: Kuphephe ukukhulelwa ngelixa usebenzisa eli yeza kwaye emva kweenyanga ezi-6 emva kokuyeka iyeza. Sebenzisa uhlobo lokuthintela ukukhulelwa olusebenza kakuhle. Thetha nogqirha wakho ngale nto.
- Amadoda: Ukuba usela eli yeza, kuphephe ukuba nguyise womntwana ngexesha lonyango kwaye kangangeenyanga ezi-3 emva kokuyeka ukusebenzisa eli yeza. Kwakhona, kuphephe ukunikela ngesidoda ngeli xesha.
- Oomama abancancisayo: Musa ukuncancisa umntwana wakho ngelixa usebenzisa eli yeza kwaye emva kwenyanga enye uyekile ukusebenzisa eli yeza.
Iziphumo ebezingalindelekanga ezinokubakho
Njengayo nayiphi na iyeza, i-Olaparib inokubangela iziphumo ebezingalindelekanga. Ezinye zazo kufuneka zixelwe ngoko nangoko, ngelixa ezinye zihlala zifika ziphele.
| Iziphumo ebezingalindelekanga ze-Olaparib | |
|---|---|
| Izinto ekufuneka uzazise ugqirha wakho ngoko nangoko | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, ulwimi. |
| Ubunzima bokuphefumla | Ukuphefumla kancinci, ukukhohlela, kunye nesandi esirhabaxa esiphuma esifubeni. |
| Iimpawu zokubala iiseli zegazi eziphantsi | Umkhuhlane, iimpawu zomkhuhlane, ukopha okungaqhelekanga okanye ukukrweleka. |
| Iimpawu zehlwili legazi | Intloko ebuhlungu ngequbuliso, iintlungu zesifuba, ukudumba emlenzeni, iintlungu, ubunzima bokuthetha, ukungabi nanto ebusweni okanye engalweni. |
| Ukudinwa okanye ubuthathaka obugqithisileyo | Ukuziva udiniwe ngaphezu kwesiqhelo. |
| Ukuba iyaqhubeka okanye iyakhathaza, xelela ugqirha wakho. | |
| Iingxaki zenkqubo yokugaya ukutya | Isicaphucaphu, ukuhlanza, iintlungu zesisu, urhudo, iintlungu zesifuba, ukungabi namdla wokutya. |
| Ezinye izifo ezincinci | Intloko ebuhlungu, utshintsho kwincasa, iintlungu zamalungu okanye zemisipha, ukwehla kobunzima, impumlo egobhozayo. |
Ndingaligcina njani iyeza?
- Gcina kude nokufikelela kwabantwana.
- Gcina phakathi kwama-20 ukuya kuma-25 degrees Celsius (ubushushu begumbi).
- Gcina iyeza kwibhotile yokuqala owawulifumene kuyo.
Umyalezo Wokuya Ekhaya
- I-Olaparib liyeza eliphambili elijolise kwiiseli zomhlaza.
- Landela imiyalelo kagqirha wakho ngokuchanekileyo. Musa ukuphula, ukutyumza, okanye ukuhlafuna iipilisi.
- Xelela ugqirha wakho ngazo zonke ezinye iziyobisi, iivithamini, kunye neemveliso zezityalo ozisebenzisayo.
- Kuphephe ukutya igrapefruit kunye neeorenji zaseSeville ngelixa usela amayeza.
- Ukuba ubona umkhuhlane, iimpawu zosulelo, okanye ukopha okungaqhelekanga, yazisa ugqirha wakho ngoko nangoko.
- Landela imiyalelo enikiweyo malunga nokukhulelwa nokuncancisa ngononophelo.
- Nokuba ufumana naluphi na usizi, ungaze uyeke unyango ngaphandle kwengcebiso kagqirha.
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