Kuqhelekile ukuba novalo kwaye ube nomdla xa ugqirha wakho ekunika iyeza elitsha nelikhethekileyo kuwe okanye kumntu osapho lwakho. Ingakumbi ukuba liyeza lomhlaza. Ngoko ke namhlanje siza kuthetha ngelinye lamayeza akhethekileyo, iPexidartinib. Lidla ngokuba phantsi kwegama lebrendi iTuralio. Makhe sithethe ngale mayeza, indlela yokuwasebenzisa, into enokuyenza, kunye nento ekufuneka siyiqaphele, ngendlela elula kakhulu, ngokungathi sithetha nomhlobo.
Kalula nje, yintoni iPexidartinib?
I-Pexidartinib ayisiyonto efana ne-chemotherapy esiqhele ukuyazi. Eli liyeza elikwicandelo lonyango olujoliswe kulo . Cinga ngako, amayeza omhlaza aqhelekileyo ngamanye amaxesha achaphazela neeseli ezilungileyo. Kodwa olu nyango lujoliswe kulo lumalunga nokufumana izinto ezifana neeproteni ezikhethekileyo kwiiseli zomhlaza kunye nokuthintela ukukhula kwazo. Kufana nokusebenzisa isitshixo esikhethekileyo ukuvula isitshixo esikhethekileyo.
Eli yeza lisetyenziswa kakhulu ukunyanga imeko yomhlaza ebizwa ngokuba yiTenosynovial Giant Cell Tumor (TGCT) . Olu luhlobo olungaqhelekanga lwethumba oluvela emalungeni. Ngoko ke, into eyenziwa leli yeza kukuthintela ukukhula kwezo seli zomhlaza nokulawula esi sifo.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale ukusebenzisa amayeza
Oku kubaluleke kakhulu. Ngaphambi kokuba ugqirha wakho agqibe ekubeni akunike eli yeza, kuya kufuneka azi imbali yakho epheleleyo yempilo. Ngoko ke, ukuba unenye yezi meko zilandelayo, nceda uxelele ugqirha wakho ngaphandle kokumfihla.
- Isifo sesibindi: Eli yeza linokuchaphazela isibindi, ngoko ke kufuneka uxelele ugqirha wakho ukuba sele unesifo sesibindi.
- Isifo sezintso: Ugqirha kufuneka aqaphele nokusebenza kwezintso.
- Ukuba uzama ukukhulelwa okanye ukhulelwe: Akucetyiswa ukuba ukhulelwe ngelixa usebenzisa eli yeza. Siza kuthetha ngale nto ngokweenkcukacha kamva.
- Ukuba ungumama oncancisayo: Oku akufanelekanga koomama abancancisayo, njengoko iyeza linokudluliselwa ebantwaneni ngobisi lwebele.
- Ezinye ii-Allergies: Sixelele ukuba unayo nayiphi na i-allergies, kungekuphela nje kwi-pexidartinib, kodwa nakweyiphi na enye iyeza, ukutya, okanye idayi.
Ugqirha wakho ufana nomhlobo wakho osenyongweni. Musa ukumfihlela nantoni na. Ukhuseleko lwakho luxhomekeke ekuchanekeni kolwazi olunikayo.
Ndingayisebenzisa njani kanye kanye le yeza?
Ukuze ufumane okuninzi kwiyeza, kubalulekile ukulisebenzisa ngokuchanekileyo. Khumbula le miyalelo ngononophelo.
1. Ikhaphu yomlomo: Le yikhaphu ekufuneka uyithathe neglasi yamanzi.
2. Ginya yonke: Nceda ungayiqhekezi, ungayityumzi, okanye ungayihlafuni le kapsuli. Ginya yonke.
3. Yisele ungenanto esiswini: Le yeyona nto ibalulekileyo. Eli yeza kufuneka lithathwe ngaphandle kokutya . Oko kukuthi, kufuneka lithathwe ubuncinane iyure enye ngaphambi okanye iiyure ezimbini emva kokutya . Ukulisela kunye nokutya kunokuchaphazela ukusebenza kweyeza.
4. Musa ukuyisebenzisa nejusi yegrapefruit: Kuphephe ukusela ijusi yegrapefruit okanye yegrapefruit ngelixa usebenzisa eli yeza. Oku kungayichaphazela kakhulu indlela elisebenza ngayo eli yeza.
5. Lumka ngee-antacids: Kuphephe ukuthatha ii-antacids ezisetyenziselwa i-gastritis (umz. iDigene, iGelusil) kwiiyure ezimbini emva kokuthatha eli yeza.
6. Yithathe ngexesha: Thatha amayeza akho ngamaxesha athile amiselweyo, njengoko ugqirha wakho ekuyalele. Musa ukuthatha ngaphezu komlinganiselo omiselweyo.
7. Musa ukuyeka ukuthatha amayeza ngaphandle kwengcebiso kagqirha: Musa ukuyeka ukuwathatha amayeza nangasiphi na isizathu ngaphandle kwengcebiso kagqirha wakho.
Yintoni omawuyenze ukuba uphoswe yidosi yeyeza?
Ukuba ulibele ukuthatha idosi, yiyeke loo dosi ngokupheleleyo. Thatha idosi elandelayo ngexesha eliqhelekileyo. Ungaze uthathe iidosi ezimbini ngaxeshanye ukuze ubuyisele idosi ephosiweyo.
Kuthekani ukuba ndithatha amayeza amaninzi kakhulu?
Ukuba ucinga ukuba ngempazamo uthathe amayeza amaninzi kunokuba ucinga, fowunela iZiko loLwazi lweePoison kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko. Okanye yiya kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.
Ezinye izinto ezinokusebenzisana nale mithi (Intsebenziswano)
I-Pexidartinib inokunxibelelana namanye amayeza, iivithamini, okanye iimveliso zezityalo ozithathayo. Kungoko ke, kubaluleke kakhulu ukuxelela ugqirha wakho malunga nawo onke amayeza, kwaneevithamini, ozithathayo. Nazi ezinye izinto ekufuneka uzilumkele ngakumbi.
| Uhlobo lweyeza/lweziyobisi | Kutheni ufanele ukhathalele? |
|---|---|
| Musa ukuzithatha ezi zinto kunye nantoni na. | |
| I-Dasabuvir, i-Ombitasvir, iParitaprevir, iRitonavir (amayeza e-hepatitis C), iRanolazine (amayeza esifo sentliziyo) | Ezi zinokubangela iziphumo ebezingalindelekanga ezibi kakhulu xa zidityaniswe nePexidartinib. |
| Xoxa ngezi zinto nogqirha wakho. | |
| Amanye amayeza okunyanga isifo sesisu (umz. iCimetidine, iFamotidine, iOmeprazole, iEsomeprazole) | Ezi zinokunciphisa ukufunxwa kwePexidartinib emzimbeni. |
| Iindlela zokulawula ukuzalwa ngeehomoni (iipilisi, iipetshi, iinaliti) | I-Pexidartinib inokunciphisa ukusebenza kakuhle kokulawula ukuzala, ngoko buza ugqirha wakho malunga nokusebenzisa olunye uhlobo lokulawula ukuzala. |
| Ijusi yegrapefruit | Amanqanaba e-Pexidartinib emzimbeni anokuba phezulu kakhulu. |
| I-St. John's Wort (imveliso yezityalo) | Oku kunciphisa ukusebenza kakuhle kwePexidartinib. |
| Ezinye ii-antibiotics kunye ne-antifungals ezifana neRifampicin, i-Itraconazole | Ezi zinokuchaphazela amanqanaba ePexidartinib. |
Iziphumo ebezingalindelekanga ezinokubakho ngelixa usela iyeza
Njengalo naliphi na iyeza, eli yeza linokubangela iziphumo ebezingalindelekanga. Asinguye wonke umntu ozifumanayo. Nangona kunjalo, kubalulekile ukuzazi ezi.
| Iimpawu ekufuneka zixelwe kugqirha wakho okanye esibhedlele (ETU) ngoko nangoko | |
|---|---|
| Iimpawu zomonakalo wesibindi | Umchamo otyheli okanye omdaka omnyama, ukutyheli kwamehlo okanye ulusu, iintlungu kwinxalenye ephezulu ngasekunene yesisu, ukudinwa kakhulu, isicaphucaphu, ukungabi namdla wokutya, kunye nendle ekhanyayo. |
| Ukwaliwa kakhulu | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi, ubunzima bokuphefumla. |
| Ukuhlanza okanye umkhuhlane | Ukuhlanza okanye umkhuhlane ongapheliyo. |
| Ukuba iyaqhubeka okanye iba yingxaki, yazisa ugqirha wakho. | |
| Utshintsho kwincasa emlonyeni | Utshintsho kwincasa yokutya. |
| Ukuqhinwa | Ubunzima bokukhupha indle. |
| Ukudumba okanye ukungakhululeki kwamalungu | Ukurhawuzelela, iintlungu, okanye ukudumba ezandleni, ezinyaweni, okanye kwiminwe. |
Isaziso esikhethekileyo malunga nokukhulelwa kunye nokuzala
Le yingongoma ebaluleke kakhulu .
- Abafazi: Kuphephe ukukhulelwa ngokupheleleyo ngelixa usebenzisa eli yeza kwaye emva kwenyanga enye uyekile ukusebenzisa eli yeza. Sebenzisa uhlobo lokuthintela ukukhulelwa oluthembekileyo ngeli xesha.
- Amadoda: Ukuba usebenzisa eli yeza, kuphephe ukuba nguyise womntwana ngelixa usebenzisa eli yeza kwaye iveki enye emva kokuba uyekile.
Eli yeza linokubangela ingozi enkulu kusana olungekazalwa. Linokubangela ukuba umntwana angazali okwethutyana okanye ngokusisigxina. Ukuba uneenkxalabo malunga noku, thetha nogqirha wakho ngaphambi kokuba uqale unyango.
Umyalezo Wokuya Ekhaya
- I-Pexidartinib liyeza elikhethekileyo elijolise kwiiseli zomhlaza. Kubalulekile ukuyithatha kanye njengoko ugqirha wakho ekuyalele, kungcono ukuba uyithathe ungakhange utye nto esiswini.
- Xelela ugqirha wakho ngazo zonke ezinye iziyobisi, iivithamini, kunye neemveliso zezityalo ozisebenzisayo. Kuphephe ukusela ijusi yegrapefruit.
- Funa uncedo lwezonyango ngokukhawuleza ukuba ubonakalisa iimpawu zokonakala kwesibindi (ukutyheli kolusu/amehlo, umchamo omnyama) okanye ukuba kukho iimpembelelo ezimbi kakhulu kwi-allergy.
- Kubaluleke kakhulu ukuphepha ukukhulelwa ngelixa usebenzisa eli yeza kwaye ixesha elithile elimiselweyo. Oku kusebenza kubafazi nakumadoda.
- Ukuba uneengxaki, imibuzo, okanye iingxaki malunga nale mithi, nceda uxoxe ngayo nogqirha wakho. Bahlala bekulungele ukukunceda.
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