Ngaba ama-ovari akho ayekile ukusebenza ngaphambi kwexesha ebekulindwe? Masifunde nge-Primary Ovarian Insufficiency (POI)!

Ngaba ukuya kwakho enyangeni ngequbuliso kuye kwangahambelani? Okanye kuye kwaphela ngequbuliso kwaye akubonakali ngathi kuyaqala kwakhona? Mhlawumbi uqala ukuba neempawu zokuya exesheni ngaphambi kokuba ufikelele kwiminyaka engama-40? Izinto ezinje zinokukwenza uzive usoyika kwaye uxhalabile. Kodwa ungakhathazeki. Namhlanje siza kuthetha ngesizathu esinye esinokubangela le meko. Oko kukungasebenzi kakuhle kwe-ovarian, okanye njengoko sikubiza ngokufutshane , i-POI (i-Primary Ovarian Insufficiency) .

Yintoni iPrimary Ovarian Insufficiency (POI)?

Ngamafutshane, i-POI (i-Primary Ovarian Insufficiency) kuxa ama-ovari akho eyeka ukusebenza kakuhle ngaphambi kokuba abe neminyaka eqhelekileyo, oko kukuthi, ngaphambi kokuba abe neminyaka engama-40. Njengoko usazi, ama-ovari entombazana ngamadlala amabini amancinci akwicala lesibeleko. La ngamalungu akhupha iqanda inyanga nenyanga, esiwabiza ngokuba yi-ovulation. Ukongeza, la ma-ovari avelisa iihomoni ezifunekayo kwizinto ezininzi ezibalulekileyo njengokuya exesheni nokukhulelwa.

Ngokwesiqhelo, ukukhutshwa kweqanda komfazi kuyayeka, okanye ukuya exesheni, xa sele eneminyaka engama-51 ubudala. Nangona kunjalo, abanye abantu abane-POI ngequbuliso bayayeka ukuya exesheni. Kwabanye, i-POI ifunyaniswa emva kweenyanga okanye iminyaka yokuya exesheni ngendlela engaqhelekanga.

Le meko yayibizwa ngokuba yi-"Premature Ovarian Failure." Kodwa ngoku oogqirha bakhetha ukusebenzisa igama elithi "Insufficiency." Oku kungenxa yokuba uphando lufumanise ukuba abafazi abane-POI ngamanye amaxesha banama-ovari asebenzayo, oko kuthetha ukuba banokukhupha amaqanda ngamaxesha angaqhelekanga. Oku kuthetha ukuba nomntu one-POI ngamanye amaxesha usenokukhupha iqanda aze akhulelwe! Enyanisweni, phakathi kwe-5% kunye ne-10% yabantu abane-POI bakhulelwa bodwa ngaphandle konyango lokuzala. Yiyo loo nto i-POI ikwabizwa ngokuba yi-"Decreased Ovarian Reserve."

Ixhaphake kangakanani le meko?

I-POI yimeko engaqhelekanga . Ichaphazela malunga ne-1% yabasetyhini abaphakathi kweminyaka eli-15 nengama-44 ubudala. Ingachaphazela abo bakha baba nabantwana kunye nabo bangazange babe nabantwana. Nangona kunjalo, ixhaphake kakhulu kubasetyhini abangaphezulu kweminyaka engama-30 ubudala.

I-POI iyichaphazela njani umzimba wakho?

Ukungabikho kakuhle kwe-Ovarian kubangela ukuba umzimba wakho ube namanqanaba aphantsi e-hormone ye-estrogen . Xa amanqanaba e-estrogen ehla, unokufumana iimpawu ezifana nezo zokuya exesheni. Umzekelo, unokufumana ubushushu, ukuncipha kwesifiso sokwabelana ngesondo, kunye notshintsho kwimo yakho. Kunokunyusa umngcipheko wakho wokufumana ezinye iimeko, ezifana ne-osteoporosis kunye nesifo sentliziyo.

Abafazi abaninzi abane-POI banengxaki yokuba nabantwana, nto leyo ethetha ukungafumani bantwana.Inokwenzeka. Nangona kunjalo, ugqirha wakho unokukwazi ukukunceda ukhulelwe umntwana. Kukho unyango loku, olufana namaqanda e-donor , i-in vitro fertilization (IVF) , okanye amayeza okuzala.

Zithini izizathu ze-POI?

Kwiimeko ezininzi, oogqirha abazi unobangela we-POI . Oku kubizwa ngokuba yi -idiopathic POI . Nangona kunjalo, uphando lubonise ukuba malunga nesithathu samatyala, kunokubakho unxibelelwano lwemfuza.

Ezinye izizathu ezinokubakho ze-POI zezi:

• Iingxaki zokuzikhusela komzimba: Umzekelo, isifo sika-Addison, isifo samathambo esibizwa ngokuba yi-rheumatoid arthritis, okanye isifo se-thyroid. Kwezi zifo, inkqubo yethu yokuzikhusela yomzimba ihlasela amalungu ethu omzimba. Oku kunokonakalisa ama-ovari.
• Unyango lomhlaza: Unyango olufana ne-chemotherapy kunye ne-radiation lunokonakalisa ama-ovari.
• Izifo zemfuza: Umzekelo, i-Turner syndrome – ebangelwa kukungaqheleki kwenye yee-chromosomes ezimbini ze-X zomfazi. Kunye ne-Fragile X syndrome – ebangelwa kukutshintsha kwe-gene ebizwa ngokuba yi-FMR1.
• Ukususwa kwesibeleko: Ngamanye amaxesha, xa isibeleko sisusiwe, ukuhanjiswa kwegazi kwii-ovari kunokupheliswa, nto leyo enciphisa ukusebenza kwazo. Nangona kunjalo, ukuba isibeleko sisusiwe kuphela kwaye ii-ovari zishiywe zinjalo, i-POI ayisoloko isenzeka.
• Iintsholongwane: Iintsholongwane ezifana ne-mumps kunye ne-HIV nazo zingonakalisa ii-ovari. Oku kucingelwa ukuba kungenxa yokuba ii-antibodies eziveliswa nxamnye nosulelo zihlasela ii-ovari.
• Ukuvezwa ixesha elide kwiikhemikhali ezinobungozi: Ukuvezwa ixesha elide kwizibulali-zinambuzane, umsi wecuba, kunye nezinye izinto ezinobungozi nako kunokuba yimbangela.

Zithini iimpawu ze-POI?

Uphawu oluqhelekileyo lwe-POI kukuyeka ukuya exesheni ngokungacwangciswanga okanye ngokupheleleyo . Nangona kunjalo, abanye abafazi basenokungabi nazo naziphi na iimpawu ezinkulu nokuba bane-POI.

Ezinye iimpawu zingabandakanya:

• Ukuya exesheni okungacwangciswanga okanye okungagqitywanga.
• Ingxaki yokukhulelwa.
• Ukuncipha kwenkanuko yesini.
• Ubunzima bokugxila.
• Ukuqumba rhoqo nokucaphuka.
• Amehlo omileyo.
• Ubushushu kunye nokubila ebusuku.
• Ukoma kwesisu.
• Isondo esibuhlungu ngenxa yokoma kwelungu lobufazi.

Khawucinge nje, unomhlobo ongakhange abe sexesheni kangangeenyanga. Akakwazi ukulala ebusuku, uyabila, aze abe nomsindo ngezinto ezincinci. Usenokuzityeshela ezi zinto, athi, "Kufuneka ukuba luxinzelelo." Kodwa ezi zinokuba ziimpawu ze-POI.

Ungayichonga njani i-POI?

Ukuba unale mpawu, kuya kufuneka ubone ugqirha. Ugqirha uza kwenza uvavanyo lomzimba , uvavanyo lwe-pelvic, kunye nembali yezonyango. Ugqirha wakho uza kukubuza nangomjikelo wakho wokuya exesheni, nokuba ubukhe wakhulelwa na ngaphambili, nokuba usebenzisa ucwangciso lokuzala na. Oku kunokunceda ugqirha wakho ukuba afumanise ukuba une-POI.

Okulandelayo, ugqirha wakho uya kuyalela uvavanyo lwegazi ukuze alinganise amanqanaba eehomoni ezithile emzimbeni wakho. Oku kuquka ukujonga amanqanaba akho eehomoni zeFollicle Stimulating Hormone (FSH) , i-Estrogen, kunye neProlactin .

Ezinye iimvavanyo ugqirha anokuzisebenzisa ziquka:

• Uvavanyo lwe-Karyotype luvavanyo lwegazi olujonga izifo zemfuza.
• I-ultrasound ye-pelvic luvavanyo lokujonga ama-ovari kunye nesibeleko.
• Uvavanyo lokukhulelwa .
• Uvavanyo lwee-antibodies ukujonga izifo ezibangelwa kukuzikhusela komzimba.

Oogqirha baxilonga i-POI ukuba ungaphantsi kweminyaka engama-40 ubudala kwaye:

• Ukuba awuhambi exesheni lakho lenyanga okanye ukuba ixesha lakho aliqhelekanga.
• Uvavanyo lwegazi lubonisa ukuba amanqanaba akho eehomoni akwinqanaba lomfazi oye wafikelela kwixesha lokuya exesheni.

Iphathwa njani i-POI?

Kukho iindlela ezahlukeneyo zokunyanga i-POI. Kuxhomekeke kwiminyaka yakho, iimpawu, kunye nokuba ufuna ukuba nabantwana na . Unyango lokungasebenzi kakuhle kwe-ovarian luquka:

• Ukunika umzimba wakho iihomoni ezingasaveliswayo zii-ovari zakho.
• Ukunyanga iimpawu ze-POI (umz., ukubila ebusuku, ukoma kwelungu lobufazi).
• Ukunciphisa umngcipheko wezinye izifo ezinokubangelwa yi-POI.
• Ukunyanga iimeko zonyango ezingaphantsi ezibangela iimpawu ze-POI zibe zimbi ngakumbi.

Unyango Lokutshintshwa Kwehomoni (HRT)

Unyango lokutshintshwa kwamahomoni (HRT) luthatha indawo yamahomoni angaveliswanga ngamaqanda akho. Oku kungenziwa ngokukunika i-estrogen yodwa okanye ngokukunika zombini i-estrogen kunye ne-progesterone.Unyango lweehomoni lunokunceda ekunciphiseni iimpawu ze-POI, ezinje ngokubila ebusuku kunye nokoma kwelungu lobufazi. Lunokunciphisa nomngcipheko we-osteoporosis kunye nezinye izifo ezinokubakho nge-POI. Ugqirha wakho angakunika unyango lweehomoni ngeendlela ezahlukeneyo, ezinje ngeepilisi, iikhrimu, iijeli, iipatches, okanye iiringi zesini.

Ukuba uqala i-HRT, kuya kufuneka uthathe unyango ude ufikelele kwiminyaka apho ukuyeka ukuya exesheni ngokwemvelo kwenzeka khona (ubudala obuphakathi kwama-51 nama-52). Kufuneka uxoxe ngezinto ezilungileyo nezingalunganga ze-HRT nogqirha wakho uze wenze isigqibo sokuba ikulungele na.

Ukongeza kwi-HRT, ezinye iindlela zonyango ziquka:

• Ukusela iipilisi ze -calcium kunye ne-vitamin D ukunciphisa umngcipheko wokuncitshiswa kwamathambo.
• Zilolonge rhoqo , phakamisa iintsimbi (ukwenzela impilo yamathambo akho), kwaye ugcine ubunzima obusempilweni.
• Ukuba unethemba lokuqala usapho kwaye ube nabantwana, kubalulekile ukuphonononga iindlela zonyango lokuzala .

Ukuba awucwangcisanga ukukhulelwa, ungalibali ukuthetha nogqirha wakho malunga neendlela zokulawula ukukhulelwa.

Ngaba oku kungaguqulwa? Ngaba ama-ovari aqala ukusebenza kwakhona?

Hayi, iPrimary Ovarian Insufficiency ayinakuguqulwa. Oogqirha banokunyanga iimpawu, iziphumo ebezingalindelekanga, kunye neemeko ezinxulumene noko, kodwa ayinakunyangwa ngokupheleleyo.

Malunga nama-25% abasetyhini abane-POI bayakwazi ukukhupha amaqanda ubuncinane kanye emva kokuba bexilongiwe . Nangona kunjalo, okwangoku akukho nyango lunokwenza ama-ovari akho aqale ukusebenza kwakhona. Unyango lwe-POI lugxile ekulawuleni iimpawu kunye nokunciphisa umngcipheko wezinye iingxaki zempilo ezinokubakho ngenxa ye-POI.

Ngaba i-POI ingathintelwa?

Ukungabikho kakuhle kwesibeleko esiphambili (Primary Ovarian Insufficiency) Ngokuqhelekileyo akunakuthintelwa. Nangona kunjalo, abafazi abasengozini enkulu yokuba ne-POI basenokufuna ukuqwalasela ukugcinwa kokuzala ukuba baceba ukuba nabantwana. Ukuba ukhathazekile nge-POI, thetha nogqirha wakho.

Ngubani osengozini enkulu yoku?

Abantu abalandelayo basengozini enkulu yokufumana ukungabikho ngokwaneleyo kwe-Ovarian Primary:

• Kwabo baneminyaka engaphezu kwama-35 ubudala.
• Abazali bemvelo kwabo bane-POI.
• Kwabo baneengxaki zokuzikhusela komzimba okanye iimeko ezithile zofuzo.
• Abo baye benza utyando lwe-pelvic, i-chemotherapy, okanye unyango lwe-radiation.

Buza kuba njani ubomi nge-POI? (Izibikezelo)

Ukungasebenzi kakuhle kwe-Ovarian Primary kudla ngokuba yimeko esisigxina.Abafazi abaninzi abanale meko kufuneka bathathe unyango lwehomoni ixesha elide ukulawula iimpawu kunye nokunciphisa umngcipheko weengxaki.

I-POI idla ngokukushiya uzive ulusizi, unesizungu, kwaye ngathi ulahlekelwe yinto ethile. Olu luvo lunokuba namandla ngakumbi ukuba usazama ukukhulelwa. Kukho amaqela enkxaso kunye neenkonzo zokunika iingcebiso ukukunceda ngeli xesha. Ngolu ncedo, unokulawula iimvakalelo zakho kwaye ufumane iindlela zokuhlangabezana nale meko.

Zeziphi ezinye iingxaki zempilo ezinokubangelwa yi-POI?

Abafazi abane-POI banamanqanaba aphantsi e-estrogen. Xa amanqanaba e-estrogen ephantsi, usengozini yokufumana ezinye iingxaki zempilo. Ezinye zezi ngxaki ziquka:

• I-Osteoporosis
• Isifo sentliziyo
• I-Hypothyroidism (I-thyroid engasebenzi kakuhle)
• Ukungazali
• Ixhala kunye noxinzelelo

Ufanele uye nini kugqirha?

Ukuba awukayi exesheni kangangeenyanga ezintathu, bonana nogqirha ngoko nangoko. Zininzi izizathu zokuba ixesha lakho liyeke, kuquka ukukhulelwa, uxinzelelo, okanye utshintsho lweehomoni. Ugqirha wakho unokukunceda ufumanise ukuba yintoni kanye kanye ebangela ukuba ixesha lakho liyeke.

Ufanele ubuze ntoni kugqirha?

Ukuba une-Primary Ovarian Insufficiency, ungabuza ugqirha wakho imibuzo efana nale:

• Ukungasebenzi kakuhle kwe-Ovarian Primary kuyichaphazela njani impilo yam iyonke?
• Ngaba ndiza kuyidinga i-hormone replacement therapy (HRT)? Ixesha elingakanani?
• Ngaba ndiza kuyidinga into yokulawula inzala?
• Ndingalufumana phi uncedo lwengqondo kunye neengcebiso?
• Yeyiphi indlela engcono kakhulu endinokuyikhetha xa ndithatha umntwana?

Yintoni umahluko phakathi kwe-POI kunye nokusilela kwe-Ovarian ngaphambi kwexesha / ukuya exesheni ngaphambi kwexesha?

Oogqirha banokusebenzisa la magama ngokutshintshana ukuchaza ukunqamka kwesisu ngaphambi kweminyaka engama-40. Ukunqamka kwesisu ngaphambi kwexesha kuxa ukuya exesheni kuyeka ngaphambi kweminyaka engama-40 kwaye awukwazi ukukhulelwa kwakhona. Kwi-POI, ama-ovari ngamanye amaxesha anokuyeka ukusebenza okwethutyana, ngoko ke kwahlukile kancinci.

Ngaba ungakhulelwa une-POI?

Ewe, kukho ithuba lokuba umfazi one-POI angakhulelwa. Ukuba une-POI kwaye uzama ukukhulelwa, ugqirha wakho wokuzala unokukunika iingcebiso ngeendlela onokukhetha kuzo. Kwakhona, ukuba awuzami ukukhulelwa, thetha nogqirha wakho ngeendlela zokuthintela ukukhulelwa.

Okokugqibela, yintoni ekufuneka uyikhumbule

Ukungasebenzi kakuhle kwe-Ovarian (i-Primary Ovarian Insufficiency) yimeko apho ama-ovari akho eyeka ukusebenza ngaphambi kokuba afikelele kwiminyaka engama-40. Oku kunokubangela iimpawu ezingathandekiyo kwaye kwandise umngcipheko wakho weengxaki zempilo ezifana ne-osteoporosis okanye isifo sentliziyo.

Kuqhelekile ukuba uzive ulusizi kwaye uxhalabile xa ufumanisa ukuba une-POI. Ingakumbi ukuba ubunethemba lokuba nomntwana. Kodwa ngonyango olufanelekileyo kunye nenkxaso, ungaqhubeka uphila ubomi obusempilweni. Thetha nogqirha wakho malunga neenkxalabo zakho. Fumana inkxaso kwiqabane lakho, usapho, kunye nabahlobo ukuze bakuncede uhlangabezane nayo. Khumbula, awuwedwa.

Ukungasebenzi kakuhle kwe-ovarian , ukungasebenzi kakuhle kwe-ovarian, i-POI, ukuyeka ukuya exesheni kwangethuba, impilo yabasetyhini, ukungalingani kwamahomoni, ukungazali