Xa wena okanye umntu omaziyo efunyenwe enomhlaza aze ugqirha wakho akuxelele ukuba uqale ukuthatha iyeza elibizwa ngokuba yiSorafenib, kuyinto eqhelekileyo ukuziva usoyika kwaye unomdla. Loluphi uhlobo lonyango olu? Lusebenza njani? Ngaba kukho naziphi na iziphumo ebezingalindelekanga? Mhlawumbi unemibuzo emininzi efana nale engqondweni yakho. Ngoko ke namhlanje, masifunde yonke into malunga neli yeza elibizwa ngokuba yiSorafenib, ngokungathi uthetha nomhlobo.
Ngamafutshane, yintoni iSorafenib?
I-Sorafenib ayifani namayeza e-chemotherapy esiwaqhelileyo. Luhlobo oluthile lwamayeza olubizwa ngokuba yi-target therapy . Cinga ngayo njengeyeza eliqhelekileyo le-chemotherapy lifana nokuqhushumba isixeko sonke, kwaye linokutshabalalisa iiseli ezilungileyo. Kodwa unyango olujoliswe kulo lufana nokufumana ngqo apho utshaba lukhona kwaye uhlasele loo ndawo kuphela.
I-Sorafenib isebenza ngokuthintela umsebenzi weeproteni ezithile ezinceda iiseli zomhlaza zikhule kwaye zenze imithambo yegazi. Oku kuthintela iiseli zomhlaza ukuba zingakhuli kwaye zisasazeke.
Isetyenziswa kakhulu ukunyanga umhlaza wesibindi , umhlaza wezintso , kunye nomhlaza we-thyroid . ESri Lanka, ungafumana eli yeza phantsi kwegama lebrendi elithi Nexavar .
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale eli yeza
I-Sorafenib liyeza elinamandla kakhulu, ngoko ke kubaluleke kakhulu ukunika ugqirha wakho inkcazo epheleleyo yemeko yakho yempilo. Ingakumbi ukuba unayo nayiphi na kwezi meko zingezantsi, qiniseka ukuba uyamxelela ngayo.
| Imeko yakho yempilo | Kutheni kubalulekile ukwazisa ugqirha? |
|---|---|
| Iingxaki zokopha | Eli yeza linokunyusa umngcipheko wokopha. |
| Isifo sentliziyo okanye ukubetha kwentliziyo okungaqhelekanga | Eli yeza linokuchaphazela ukusebenza kwentliziyo kunye nesantya sentliziyo. |
| Igazi elonyukayo | I-Sorafenib inokunyusa uxinzelelo lwegazi ngakumbi, ngoko ke kubalulekile ukuyilawula. |
| Ezinye izifo zesibindi | Ukuba sele unengxaki yesibindi, isiphumo seyeza sinokutshintsha. |
| Ukuba usandul' ukwenza okanye uza kutyandwa | Eli yeza linokulibazisa inkqubo yokuphiliswa kwenxeba. |
| Ukuba ukhulelwe okanye uzama ukukhulelwa | Oku kubaluleke kakhulu. Eli yeza linokubangela ingozi enkulu kumntwana ongekazalwa. |
| Ukuba umntwana uncanciswa | Eli yeza linokudlula kubisi lwebele kwaye lonakalise umntwana. |
| Ukunganyamezelani kwamanye amayeza, ukutya okanye izinto | Kubalulekile ukwazi ukuba une-allergy kwiSorafenib okanye nakweyiphi na izithako zayo. |
Yeyiphi indlela echanekileyo yokusela amayeza?
Le pilisi mayithathwe ngomlomo neglasi yamanzi.
- Musa ukuphula, ukutyumza, okanye ukuhlafuna ipilisi. Yiginye yonke.
- Eyona nto ibalulekileyo: Oku kufanele kuthathwe ungenanto esiswini . Oko kukuthi, ubuncinane iyure enye ngaphambi okanye iiyure ezimbini emva kokutya. Ukukuthatha kunye nokutya kuya kunciphisa ukufunxwa kweyeza emzimbeni.
- Sela amayeza akho kanye njengoko ugqirha wakho ekuyalele, ngexesha elimiselweyo. Musa ukuyeka ukuwasela wedwa. Kuphephe ukuyeka amayeza ngaphandle kwengcebiso kagqirha.
Ingqalelo: Ukuba ucinga ukuba uthathe amayeza amaninzi kakhulu, musa ukuchitha ixesha kwaye yiya kwiYunithi yoNyango oluNgxamisekileyo (ETU) ekufutshane nawe ngoko nangoko . Okanye utsalele umnxeba iZiko loLwazi lweeTyhefu zeSizwe kwiSibhedlele sikaZwelonke saseColombo .
Yintoni omawuyenze ukuba uphoswe yidosi yeyeza?
Ukuba uphoswe yidosi, yithathe ngokukhawuleza xa ukhumbula. Kodwa ukuba sele kuza kufuneka uyithathe idosi elandelayo, yitsibe idosi oyiphosileyo uze uthathe idosi elandelayo ngexesha elicwangcisiweyo. Ungaze uthathe iidosi ezimbini ngaxeshanye.
Ngaba kukho iingxaki ngamanye amayeza? (Ukusebenzisana kwamayeza)
Ewe, iSorafenib liyeza elinokusebenzisana namanye amayeza. Ngoko ke, kufuneka uxelele ugqirha wakho ngawo onke amayeza owasebenzisayo, kuquka lawo amiselwe ngugqirha wakho, lawo athengwe kwikhemesti, amayeza esintu, iivithamini, kunye nezongezo zemifuno.
Ngokukodwa, kuphephe ukuthatha iSorafenib kunye namayeza alandelayo:
- I-Cisapride
- I-Dronedarone
- I-Pimozide
- I-Thioridazine
Kwakhona, kubalulekile ukwazisa ugqirha wakho ukuba usebenzisa la mayeza alandelayo, njengoko anokuchasana neSorafenib.
- Amayeza okulwa nokuxhuzula (umz. iCarbamazepine, iPhenobarbital, iPhenytoin)
- Iintlobo zee-antibiotics (umz. iRifampin, iRifabutin)
- I-Dexamethasone (uhlobo lwe-steroid)
- I-Digoxin (iyeza lesifo sentliziyo)
- Imveliso yemifuno yeSt. John's Wort
- Amanye amayeza achaphazela izinga lentliziyo (achaphazela ixesha le-QT)
- I-Vinblastine (elinye iyeza lokulwa nomhlaza)
Olu luhlu aluphelelanga, ngoko ke xelela ugqirha wakho malunga nawo onke amayeza owasebenzisayo.
Izinto ekufuneka uzikhumbule xa usebenzisa amayeza
Ukukhulelwa kunye nokuzala
Le yeyona nto ibalulekileyo ekufuneka uyilumkele.
- Abafazi: Kuphephe ukukhulelwa ngelixa usebenzisa la mayeza. Akucetyiswa ukuba ukhulelwe ukuya kuthi ga kwiinyanga ezi-6 emva kokuyeka amayeza. Thetha nogqirha wakho malunga nendlela yokulawula ukukhulelwa esebenza kakhulu.
- Amadoda: Ukuba usela eli yeza, kufuneka uphephe ukuba nguyise womntwana ngelixa usela eli yeza kwaye kangangeenyanga ezi-3 emva kokuba uyekile. Kubalulekile ukuba wena neqabane lakho nisebenzise uhlobo olusebenzayo kakhulu lokuthintela ukukhulelwa.
Ngenxa yokuba eli yeza linokubangela ingozi enkulu nehlala ihleli kusana olungekazalwa, kufuneka ungancancisi ngokupheleleyo xa usebenzisa eli yeza.
Utyando kunye nokuphiliswa kwamanxeba
Ukuba uza kwenza naluphi na utyando okanye umsebenzi wamazinyo, xelela ugqirha wakho okanye ugqirha wamazinyo kwangaphambili ukuba usebenzisa iSorafenib. Ngenxa yokuba eli yeza linciphisa inkqubo yokuphiliswa, lidla ngokuqaliswa kwiiveki ezimbini emva kotyando olukhulu.
Ukopha kunye nosulelo
Eli yeza linokubangela ukukrweleka nokuphuma kwegazi okulula, kwaye linokunciphisa amandla omzimba okulwa nosulelo.
- Ukuba ubona ukopha okungaqhelekanga (umz. kwiintsini, impumlo), xelela ugqirha wakho.
- Lumka xa uhlamba amazinyo akho kwaye usebenzisa amazinyo okuxuba amazinyo.
- Ukuba ubonakalisa iimpawu ezifana nomkhuhlane, umkhuhlane, okanye umphimbo obuhlungu, musa ukuzinyanga kwaye uthethe nogqirha wakho. Ziphephe iindawo apho abantu abagulayo bahlanganisana khona.
Zithini iziphumo ebezingalindelekanga ezinokubakho?
Njengayo nayiphi na iyeza, iSorafenib inokuba nemiphumo emibi. Asinguye wonke umntu oyifumanayo, kodwa kubalulekile ukuba uzazi.
| Uhlobo lwesiphumo esibi | Iimpawu |
|---|---|
| Iziphumo ebezingalindelekanga ezinzulu ekufuneka zixelwe kugqirha wakho ngoko nangoko | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, ulwimi, ubunzima bokuphefumla. |
| Iimpawu zokopha | Indle emnyama, ehlala ixesha elide; ukuhlanza igazi okanye indle ebonakala ngathi yikofu. |
| Iimpawu zokuhlaselwa yintliziyo | Intlungu yesifuba okanye ukuqina, ukubetha kwentliziyo okukhawulezayo okanye okungahambelaniyo. |
| Iingxaki zesibindi | Ukutyheli kwamehlo okanye ulusu, umchamo omnyama, iintlungu kwicala eliphezulu lasekunene lesisu. |
| Iimpawu zesikhumba eziqatha | Ubomvu, iintlungu, amadyungudyungu, okanye izilonda ezintendeni zezandla kunye neenyawo. Izilonda ezingaphakathi emlonyeni. |
| Ezinye iimpawu eziqatha | Intlungu ebuhlungu esiswini, isiyezi, ukuziva utyhafile. |
| Iziphumo ebezingalindelekanga ezingaqhelekanga, kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka | |
| Inkqubo yokugaya ukutya | Urhudo, ukuphelelwa ngumdla wokutya. |
| Utshintsho lomzimba | Ukulahlekelwa ziinwele, ukudinwa, ukwehla kobunzima. |
Umyalezo Wokuya Ekhaya
- I-Sorafenib lunyango olujoliswe kulo oluthintela ukukhula kweeseli zomhlaza.
- Soloko usela eli yeza ungenanto esiswini, oko kukuthi iyure enye ngaphambi okanye iiyure ezimbini emva kokutya.
- Qiniseka ukuba wazisa ugqirha wakho ngazo zonke ezinye iziyobisi ozisebenzisayo.
- Funa uncedo lwezonyango ngokukhawuleza ukuba ufumana iziphumo ebezingalindelekanga ezinje ngeentlungu zesifuba, ukusabela okuqatha kwesikhumba, okanye ukopha okungaqhelekanga.
- Kuphephe ukukhulelwa ngokupheleleyo ngelixa usebenzisa eli yeza kwaye kangangeenyanga ezimbalwa emva kokuliyeka. Oku kusebenza kubafazi nakumadoda.
- Ungaze uyeke ukuthatha amayeza akho okanye utshintshe umthamo ngaphandle kwengcebiso kagqirha wakho. Thetha nabo ngayo nayiphi na ingxaki.
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