Masifunde ngotshintsho kwiiseli zomzimba wethu. Yintoni iSquamous Metaplasia?

Ngaba wakha wacinga ukuba neeseli ezincinci ngaphakathi emizimbeni yethu ngamanye amaxesha zinokutshintsha? Oku kunokuba yinto eqhelekileyo, kwaye ngamanye amaxesha kunokuba yinto ekufuneka ixhalatyelwe. Olunye utshintsho olunjalo lweeseli lubizwa ngokuba yi-`(Squamous Metaplasia)`. Namhlanje, siza kuthetha ngale nto ngokulula, ngendlela onokuyiqonda.

Yintoni kanye kanye `(Squamous Metaplasia)`?

Ngamafutshane, iSquamous Metaplasia lutshintsho olungenabungozi, olungengomhlaza kwiiseli ze-squamous ze -epithelium yomzimba wakho. Cinga ngayo le epithelium ifana nolusu lwethu, i-membrane ekhuselayo egubungela amadlala kunye namalungu ethu omzimba.

Ngoku kulula ukujonga intsingiselo yala magama mabini ngokwahlukeneyo:

• I-Squamous: Ezi ziiseli ezincinci, ezithe tyaba ezifana nezikali. Ezi zezona zenza i-epithelium.
• `(Metaplasia)`: Oku kuthetha ukuba uhlobo oluthile lweseli luyatshintsha lube luhlobo olwahlukileyo ngokupheleleyo lweseli. Into ekhethekileyo kukuba olu hlobo lutsha lweseli oluyilwayo lolo lungaqhelekanga ukufumaneka kuloo tissue.

Ngoko ke, kwi-`(Squamous Metaplasia)`, iiseli eziqhelekileyo ze-`(squamous)` zithathelwa indawo ziiseli ze-`(squamous)`. Kodwa uninzi lwexesha oku akuyomhlaza. Kodwa kwezinye iimeko ezingaqhelekanga, le meko inokuba ngumhlaza`(oyingozi).`

Ngaba kukho iintlobo ze-`(Squamous Metaplasia)`?

Ewe, oogqirha bahlula ezi seli njenge-"Squamous Metaplasia" ngokusekwe kwindlela ezitshintsha ngayo. Kukho iintlobo ezimbini eziphambili:

1. `Keratinizing Squamous Metaplasia` okanye `(Leukoplakia)`:

• Kolu hlobo, iiseli zakho zivelisa iproteni eninzi ebizwa ngokuba yi-keratin njengoko zisuka kwelinye ilaphu le-epithelium ziye kwelinye.
• Kwiiseli eziqhelekileyo ezisempilweni, le protein ebizwa ngokuba yi-keratin inceda ekwakheni izicubu zethu, iinwele, ulusu kunye nezinzipho. Ikwayila ulwelo lwamalungu kunye namadlala.
• Kodwa kolu hlobo, i-`(keratin)` eninzi kakhulu iyaqokelelana.

2. `I-Nonkeratinizing Squamous Metaplasia`:

• Okwenzekayo koku kukuba, njengoko bekutshiwo ngaphambili, inani elikhulu leproteni (oko kukuthi, `(keratin)`) aliqokeleli ngaphakathi kwiiseli. I-Keratinization ayenzeki.

Kwezi ntlobo zimbini, enye ifanelwe yingqwalasela ethile.

Ngaba oku kukhokelela kumhlaza? Imeko "engaphambi komhlaza"?

Le yeyona nto ibalulekileyo.

• I-Nonkeratizing Squamous Metaplasia yimeko engeyomhlaza. Oku kuthetha ukuba ayizukuba ngumhlaza. Ngoko ke akukho nto ifanele ixhalabe ngayo.
• Nangona kunjalo, i-'Keratinizing Squamous Metaplasia'Olu hlobo ngamanye amaxesha lunokuba "lungaphambi komhlaza". Oku kuthetha ukuba ukuba alunyangwa kakuhle, lunokukhula lube ngumhlaza ngokuhamba kwexesha.

Yiyo loo nto oogqirha beyinika ingqalelo engakumbi xa befumanisa `(iKeratinizing Squamous Metaplasia)'.

Kuza kwenzeka ntoni ukuba iSquamous Metaplasia iba ngumhlaza?

Umbuzo omhle. Ukuba imeko ekhankanyiweyo ngaphambili, ethi ``Keratinizing Squamous Metaplasia'', ayinyangwa, iya kuqala ibe yimeko ebizwa ngokuba yi ``Dysplasia .'' ``Dysplasia'' kukwanda okungaqhelekanga kwenani leeseli kwizicubu okanye kumalungu omzimba. Cinga ngayo njengeqela leeseli ezisebenza ngaphandle komthetho.

Emva koko, ukuba le meko `(Dysplasia)` ayinyangwa, inokuba yi` (Neoplasia)` (neoplasia) . Emva koko, okwenzekayo kukuba, ezo seli zingahambelaniyo zikhula ngokukhawuleza ngaphandle kolawulo, zenze i`(neoplasm)` (neoplasm), oko kukuthi, `(ithumba).` Eli thumba linokuba ngumhlaza okanye lingabi ngumhlaza.

Xa iiseli ze-squamous ziba ngumhlaza, sibiza ngokuba yi -squamous cell carcinoma . Usenokuba ukhe weva eli gama njengohlobo lomhlaza wesikhumba. Kodwa umhlaza wesikhumba luhlobo olunye kuphela. Ezi seli ze-squamous zikwafumaneka kwiinwebu zomlomo wethu, impumlo, iindlela zomoya, kunye nomlomo wesibeleko.

Yintoni iCervical Squamous Metaplasia?

Nangona le meko, ebizwa ngokuba yiSquamous Metaplasia, inokuvela naphi na kwi-epithelium yethu, ixhaphake kakhulu kwiiseli ezenza i-mucus ze-endocervix, inxalenye yenkqubo yokuzala yabasetyhini. I-endocervix yindlela engaphakathi komlomo wesibeleko edibanisa isibeleko kunye nelungu lobufazi.

Okubalulekileyo kukuba, i-Nonkeratinizing Cervical Squamous Metaplasia ixhaphake kakhulu kubasetyhini. Ithathwa njengotshintsho oluqhelekileyo. Malunga nesibhozo kwabasetyhini abalishumi abakwiminyaka yokuzala banale meko. Ikwabonakala nakubafazi abathathu kwabane abaye badlula kwixesha lokuya exesheni. Olu tshintsho luqhelekileyo lweseli alunyusi umngcipheko womhlaza.

Nangona kunjalo, abanye abantu abosulelwe yiHuman Papillomavirus (HPV) banokuba nesifo esibizwa ngokuba yiSquamous Metaplasia, esinokuba sisiseko somhlaza. Njengoko usazi, iHPV sesona sifo sixhaphakileyo esidluliselwa ngesondo (STD). ISquamous Metaplasia, ebangelwa yiHPV, inokuba yimeko ebizwa ngokuba yiCervical Dysplasia okanye iCervical Intraepithelial Neoplasia. Ukuba ayinyangwa, olu tshintsho lweeseli lunokukhokelela kumhlaza womlomo wesibeleko.

Yiyo loo nto oogqirha besoloko bexelela abafazi ukuba benze uvavanyo olufana ne-"Pap Smear". Ukuba olu tshintsho lubonwa kwangethuba, kulula ukulunyanga.

Kuphi na apho iSquamous Metaplasia inokwenzeka khona?

I-Squamous Metaplasia inokukhula nakwezinye iindawo:

• Isinyi kunye nenkqubo yomchamo
• Inkqubo yokugaya ukutya
• Iitoni emlonyeni, elulwimini, nasemqaleni
• Inkqubo yokuphefumla
• Ulusu

Zithini izizathu zeSquamous Metaplasia?

Iingcali azikayazi kakuhle ukuba kutheni ezinye iiseli zitshintsha ngolu hlobo, nto leyo ebangela `(Squamous Metaplasia)`. Nangona kunjalo, kukho izinto ezininzi eziye zachongwa ezonyusa umngcipheko wokukhula kweentlobo ezithile ze `(Squamous Metaplasia). Umzekelo:

• Unyango lweehomoni kunye nonyango lwemitha yomhlaza weprostate kumadoda lunokubangela i-squamous metaplasia kwi-urethra (ityhubhu ethwala umchamo ukusuka kwisinyi ukuya ngaphandle komzimba).
• Usulelo lwe-HPV lunokubangela i-cervical squamous metaplasia.
• Abantu abaye batyandwa umchamo ixesha elide, abanezifo ezibangelwa kukwasulelwa yi-urinary tract (UTIs), okanye abanamatye ezintso banokuba ne-bladder squamous metaplasia.
• Abantu abatshayayo kunye nabo banesifo semiphunga esibizwa ngokuba yiChronic Obstructive Pulmonary Disease (COPD) basengozini enkulu yokufumana i-bronchial squamous metaplasia.
• Ukunqongophala kweVithamini A kunokubangela iSquamous Metaplasia kwindlela yokuphefumla.

Kusenokuba nezizathu ezininzi zoku, kodwa akunakutshiwo ukuba zonke zibangelwa zezi zizathu.

Zithini iimpawu ze-`(Squamous Metaplasia)`?

Iimpawu zale meko ziyahluka ngokuxhomekeke kwinxalenye yomzimba echaphazelekileyo yile meko (iSquamous Metaplasia). Abantu abaninzi basenokungabi nazo iimpawu ezibonakalayo. Oku kuthetha ukuba le meko inokubakho emzimbeni ngaphandle kokubangela ukungonwabi.

Kodwa abanye abantu banokuba neempawu.

• Abantu abane-bladder squamous metaplasia banokufumana ukungakwazi ukuzibamba (isidingo sokuchama ngequbuliso).
• I-Cervical Squamous Metaplasia inokubangela ukudumba komlomo wesibeleko, okwaziwa ngokuba yi-cervicitis. Le meko ayisoloko ibangela iimpawu. Nangona kunjalo, ukuba iimpawu ziyenzeka, zingabandakanya:
• Ukuphuma kwamanzi kwilungu lobufazi elinuka kakubi okanye ukurhawuzelelwa okanye ukutsha kwilungu lobufazi.
• Intlungu ngexesha lokwabelana ngesondo (i-dyspareunia).

Ngoko ke uyabona, iimpawu zinokwahluka ukusuka kumntu ukuya komnye, kwaye ngamanye amaxesha zisenokungabikho kwaphela iimpawu.

Ungayixilonga njani le meko?

Indlela yokuvavanya iSquamous Metaplasia nayo iyahluka ngokuxhomekeke kwinxalenye yomzimba echaphazelekileyo.

• Oogqirha basebenzisa ii-Pap smears ukujonga utshintsho kwiiseli zomlomo wesibeleko kunye ne-endocervix. Bakwavavanya i-HPV ukuze babone ukuba ukhe wasulelwa yi-HPV ngaphambili na. Ukuba iziphumo zezi mvavanyo zibonisa umngcipheko wokuba nomhlaza womlomo wesibeleko, ungathunyelwa kwi -colposcopy . Oku kubandakanya ukuvavanya ngakumbi iiseli zomlomo wesibeleko.

• Kwezinye iintlobo ze-squamous metaplasia, ugqirha wakho unokuthatha isampuli yeeseli kwindawo echaphazelekayo aze enze i-biopsy . Ingcali (ebizwa ngokuba yi-pathologist) iya kujonga ezi seli phantsi kwe-microscope ukujonga naluphi na utshintsho okanye iimpawu zesifo.

Ngoko ke ukuba unengxaki yokungakhululeki, okanye ugqirha urhanela ukuba kukho imeko efana nale, uza kwenza uvavanyo olufanelekileyo.

Iphathwa njani iSquamous Metaplasia?

Uyakhumbula sithethe ngohlobo olubizwa ngokuba yi-"Nonkeratinizing Squamous Metaplasia"? Olu hlobo alusoloko lufuna unyango kuba aluguquki lube ngumhlaza.

Nangona kunjalo, uhlobo olubizwa ngokuba yi-`(Keratinizing Squamous Metaplasia)` lunokunyusa umngcipheko womhlaza, ngoko ke kufuneka ulumke ngalo.

Ugqirha wakho uza kwenza uvavanyo rhoqo ukujonga naziphi na iimpawu zomhlaza. Ukuba naluphi na utshintsho kwiseli lubonisa ingxaki, ugqirha wakho uza kugqiba ukuba loluphi unyango olungcono ngokusekelwe kwinxalenye yomzimba echaphazelekileyo.

Indlela yonyango ixhomekeke ekubeni imeko imbi kangakanani, apho ikhoyo, kunye nempilo yakho iyonke.

Ndimele ndibuze ntoni kugqirha wam?

Ukuba ufunyaniswe uneSquamous Metaplasia, unokuba nemibuzo emininzi. Oku kuqhelekile. Nazi ezinye zezinto onokuzibuza ugqirha wakho:

• Ingaba yintoni isizathu sokuba ndiphuhlise le `(Squamous Metaplasia)`?
• Ngaba ndisengozini yokuba nomhlaza?
• Ndingenza ntoni ukunciphisa lo mngcipheko?
• Ngaba ndifuna unyango? Ukuba kunjalo, loluphi uhlobo?
• Ndifanele ndihlolwe kangaphi?
• Ngaba kukho naziphi na iingxaki endifanele ndizixhalabise ngazo?

Ungoyiki ukubuza le mibuzo. Kubaluleke kakhulu ukuba uyiqonde kakuhle imeko yakho.

Umyalezo Wokuya Ekhaya

I-Squamous Metaplasia lutshintsho olungengomhlaza kwiiseli ze-epithelium, izicubu ezigubungela amalungu ethu kunye namadlala. Abantu abaninzi, ingakumbi abafazi, banohlobo olubizwa ngokuba yi-Nonkeratinizing Cervical Squamous Metaplasia. Oku akunyusi umngcipheko womhlaza.

Nangona kunjalo, uhlobo olubizwa ngokuba yi-"Keratinizing Squamous Metaplasia" lunokuguquka lube yi-"Dysplasia" kwaye mhlawumbi lube ngumhlaza. Ngoko ke ugqirha wakho uya kujonga rhoqo iiseli zakho ukuze abone utshintsho ukuze akhangele iimpawu zomhlaza.

Eyona nto ibalulekileyo kukuba ukuba unamathandabuzo okanye ukungakhululeki, okanye ukuba ugqirha ukhankanya oku, ungoyiki ukubuza, ufumane ulwazi olufanelekileyo, kwaye ufumane uvavanyo olufunekayo kunye nonyango (ukuba kuyimfuneko). Landela rhoqo icebiso likagqirha wakho.

I- Squamous Metaplasia, utshintsho lweeseli, i-epithelium, i-keratin, i-precancerous, umlomo wesibeleko, i-HPV