Wena nezalamane zakho ninezinto ezininzi ezifanayo, akunjalo? Amehlo aluhlaza okwesibhakabhaka, ubude, kunye nezifo ezifana ne-asthma kunye nesifo sentliziyo zonke zinokudluliselwa kwizizukulwana ngezizukulwana. Ngoko ke ukuba unesifo seswekile sohlobo loku-1, usenokuba uzibuza, "Ngaba le yinto endiyizuzile njengelifa?" Kwaye usenokuba nexhala lokuba nabantwana bakho baya kufumana esi sifo. Kubalulekile ukuqaphela oku.
Okokuqala, masiqonde ukuba yintoni isifo seswekile sohlobo loku-1?
Ngamafutshane, isifo seswekile sohlobo loku-1 sisifo esibangelwa kukuzikhusela komzimba . Tata, ngaba oko kuvakala kuyinkimbinkimbi? Kulungile, mandikuchaze ngokulula. Khawucinge ukuba kukho umkhosi okhusela ilizwe lethu. Umsebenzi kuphela waloo mkhosi kukukhusela ilizwe kwiintshaba zangaphandle. Umzimba wethu ukwanenkqubo yokuzikhusela efanayo. Siyibiza ngokuba yinkqubo yokuzikhusela . Umsebenzi wayo kukuchonga nokutshabalalisa iintshaba zangaphandle ezifana neentsholongwane, iintsholongwane, kunye neebhaktheriya ezibangela izifo, nokusigcina sisempilweni.
Nangona kunjalo, kwesi sifo sokuzikhusela komzimba, inkqubo yethu yokuzikhusela ihamba kakubi kancinci kwaye ayikwazi ukwahlula phakathi kweeseli zethu ezilungileyo kunye neentshaba zangaphandle. Kufana nomkhosi wethu ohlasela abantu abamsulwa kwilizwe lethu.
Kwisifo seswekile sohlobo loku-1, le nkqubo yokuzikhusela yomzimba engalunganga ihlasela uhlobo oluthile lweseli kwipancreas yethu ebizwa ngokuba yi-'beta cells' . Ezi seli ze-beta zezo zenza i-hormone insulin, ebaluleke kakhulu emizimbeni yethu. I-insulin yiyo ethatha iswekile (iglucose) ekutyeni esikutyayo ize iyithumele kwiiseli ukuze iguqulwe ibe ngamandla. Ngoko ke xa inkqubo yokuzikhusela yomzimba itshabalalisa ezi seli ze-beta, ukuveliswa kwe-insulin kuyayeka ngokupheleleyo. Kulapho ke isifo seswekile sohlobo loku-1 siqala khona.
Ngoko ke isizukulwana sinxulumene njani noku?
Ewe, isifo seswekile sohlobo loku-1 sifumaneka kwiintsapho. Oko kuthetha ukuba kukho unxibelelwano oluthile lwemfuza. Ukuba umama wakho, utata, umnakwenu, udadewenu, okanye umntwana wakho unesifo seswekile sohlobo loku-1, unamathuba aphindwe kalishumi elinesihlanu okuba nesi sifo kunomntu ongenamalungu osapho onaso.
Kodwa khumbula oku: Musa ukoyika xa usiva oku. Ukuba nje unamathuba aphindwe kalishumi elinesihlanu okufumana esi sifo akuthethi ukuba ngokuqinisekileyo uza kusifumana.
Okumangalisayo kukuba, ama-85% abantu abanesifo seswekile sohlobo loku-1, okanye abantu abangaphezu kwesibhozo kwabalishumi, abanayo imbali yesifo kwiintsapho zabo . Kwakhona, nokuba kukho umntu kusapho onesi sifo, amathuba okuba abanye basifumane aphantsi kakhulu.
Ngoko ke oku kwenzeka njani? Ingaba yimfuza nje?
Hayi. Into ebalulekileyo kukuba, ii-genes zodwa azingonobangela.Cinga ngee-genes njengeqela le-gunpowder elungele ukutshiswa. Kodwa ukuze itshise, ifuna intlantsi yangaphandle. Elo ntlantsi yinto esiyibiza ngokuba 'zizinto ezingqongileyo' .
Oogqirha noososayensi basazama ukufumanisa ukuba yintoni kanye kanye le 'spark'. Isenokuba lusulelo lwentsholongwane, into ethile ekutyeni esikutyayo, okanye enye into enxulumene nokusingqongileyo. Ngoko ke, ukuze umntu abe nesifo seswekile sohlobo loku-1, kufuneka abe ne-genes ezimenza afumane esi sifo, kwaye kufuneka abe sengozini yokusingqongileyo ebangela ezo genes. Xa zombini ezi zinto zidibana, inkqubo yomzimba yokuzikhusela iyaphazamiseka ize iqalise ukuhlasela iiseli ze-beta.
Zeziphi ii-genes ezinxulumene nesifo seswekile sohlobo loku-1?
Izazinzulu zenza uphando oluninzi malunga notshintsho lwezakhi zofuzo oluhambelana nesifo seswekile sohlobo loku-1. Uninzi lwale mizila luchaphazela indlela esebenza ngayo inkqubo yethu yomzimba yokuzikhusela. Enye yezona zibalulekileyo kwezi yi-HLA (Human Leukocyte Antigen) . Ezi mizila ze-HLA zezona zifundisa inkqubo yomzimba yokuzikhusela ukwahlula phakathi "kweeseli zethu kunye neeseli zangaphandle." Ngoko ke, ukuba kukho isiphene kwezi mizila ze-HLA, inkqubo yomzimba yokuzikhusela ayinakukwazi ukwenza olu mahluko ngokufanelekileyo.
Ezi genes ze-HLA zahlulwe ngakumbi zibe ziintlobo ezahlukeneyo. Ungafumana umbono olula woku kwitheyibhile engasezantsi.
| Uhlobo lweGene | Impembelelo kwiSifo seswekile sohlobo loku-1 |
|---|---|
| I-HLA-DR2 | Kubonakala ngathi ikhusela isifo seswekile sohlobo loku-1 ngandlela ithile. |
| I-HLA-DR3 okanye i-HLA-DR4 | Isifo seswekile sohlobo loku-1 siyandisa umngcipheko . Sixhaphake kakhulu kubantu abamhlophe. |
| I-HLA-DR7 | Abantu abamnyama bachongiwe njengabasengozini enkulu . |
| I-HLA-DR9 | Kuye kwafunyaniswa ukuba kwandisa umngcipheko kubantu baseJapan. |
Ukongeza, ezinye iinguqulelo kwi-INS gene, eyalela umzimba ukuba uvelise i-insulin, zinokunxulunyaniswa nesifo seswekile sohlobo loku-1.
Olu vavanyo lwemfuza ngoku ludla ngokwenziwa kwinqanaba lophando. Ukuba ufuna ukwazi okungakumbi ngale nto okanye unenkxalabo malunga nembali yosapho lwakho, kungcono ukuthetha ngokukhululekileyo nogqirha wakho ngayo.
Umyalezo Wokuya Ekhaya
- Isifo seswekile sohlobo loku-1 sisifo esibangelwa sisiphene kwinkqubo yomzimba yokuzikhusela (isifo sokuzikhusela komzimba), endaweni yokuba sibangelwe lufuzo.
- Nangona ukuba nelungu losapho elinesifo seswekile sohlobo loku-1 kwandisa umngcipheko wakho wokuba nesi sifo, akuthethi ukuba wena okanye umntwana wakho uza kuba naso.
- Uninzi lwabantu abanesifo seswekile sohlobo loku-1 (malunga nama-85%) abanayo imbali yesifo kwiintsapho zabo.
- Ukuze esi sifo sivele, kufuneka ufuzo kunye nesizathu sokwenzeka kwaso .
- Ukuba unenkxalabo okanye amathandabuzo malunga nembali yentsapho yakho yesifo seswekile okanye umngcipheko womntwana wakho, thetha nogqirha wakho ngayo kwaye ufumane ingcebiso efanelekileyo.
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