Ukuba wena okanye umntu omaziyo une-cystic fibrosis, ugqirha wakho usenokuba unikile eli yeza libizwa ngokuba yiTezacaftor; Ivacaftor. Igama lophawu lwale yeza yiSymdeko. Ekubeni eli liyeza lanamhlanje elikhethekileyo, kubaluleke kakhulu ukwazi kakuhle ngalo kwaye ulisebenzise ngokuchanekileyo. Ke namhlanje, masithethe nje ngeli yeza, indlela elisebenza ngayo, indlela yokulithatha, kunye nayo yonke into ekufuneka uyilumkele.
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Yintoni iTezacaftor; iIvacaftor?
Ngamafutshane, le yipilisi esetyenziselwa ukunyanga isifo esibizwa ngokuba yiCystic Fibrosis (CF). Nangona kunjalo, ayinikwa bonke abaguli abaneCF. Eli yeza lisebenza kuphela kubantu abaneenguqu ezithile kwizakhi zabo zofuzo. Ugqirha wakho uza kwenza uvavanyo olufunekayo ukuze abone ukuba eli yeza lifanelekile na kuwe. Linceda ukulungisa ingxaki ngeeproteni emzimbeni wakho ezibangelwa yiCF. Ugqirha wakho angakunika yona ngezinye izizathu. Ngoko ke ukuba unemibuzo, buza ugqirha wakho.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale eli yeza
Ngaphambi kokuba ugqirha wakho akunike eli yeza, kuya kufuneka azi imbali yakho epheleleyo yempilo. Ngoko ke, ukuba unenye yezi meko zilandelayo, qiniseka ukuba uxelele ugqirha wakho .
- Ukuba unesifo sezintso.
- Ukuba unesifo sesibindi.
- Ukuba ukhe waba ne-allergy engaqhelekanga kwizithako zeTezacaftor, Ivacaftor, okanye nakweyiphi na enye iyeza, ukutya, okanye isithinteli.
- Ukuba ukhulelwe, okanye ulindele ukukhulelwa kungekudala.
- Ukuba ungumama oncancisayo.
Kubaluleke kakhulu kukhuseleko lwakho ukuxelela ugqirha olu lwazi ngaphandle kokulufihla.
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Check Availability →Ndingayisebenzisa njani kanye kanye le yeza?
Ukuze ufumane okuninzi kweli yeza, kufuneka ulithathe kanye njengoko uyalelwe.
- Yithathe nesidlo esinamafutha: Eli yeza kufuneka lisetyenziswe nesidlo esinamafutha rhoqo. Umzekelo, amaqanda, itshizi, ibhotolo yamandongomane, iavokhado, njl.njl. ziya kunceda umzimba ukuba ulifunxe kakuhle iyeza.
- Ginya ithebhulethi yonke: Musa ukuyiqhekeza, ukuyityumza, okanye ukuyihlafuna . Ginya yonke ngeglasi yamanzi.
- Musa ukuyithatha neGrapefruit Juice: Oku kubaluleke kakhulu. Kuphephe ukutya okanye ukusela iidiliya okanye ijusi yegrapefruit ngokupheleleyo ngelixa usebenzisa eli yeza.Ingaphazamisa ukusebenza kakuhle kweyeza.
- Lithathe ngexesha: Thatha amayeza akho ngexesha elichazwe ngugqirha wakho, ngamaxesha afanelekileyo. Ukuba kube kanye ngemini, zama ukuwathatha ngexesha elifanayo yonke imihla.
- Musa ukuyeka ukuthatha amayeza akho ngaphandle kwengcebiso kagqirha wakho: Musa ukuyeka ukuthatha amayeza akho ngaphandle kokubuza ugqirha wakho kuqala, nokuba kungenxa yokuba uzive ungcono okanye ngenxa yesinye isizathu.
Ukuba unika abantwana eli yeza...
Eli yeza ngamanye amaxesha licetyiswa kubantwana abaneminyaka engaphezu kwemithandathu ubudala. Nangona kunjalo, esi sisigqibo esiya kwenziwa ngugqirha wezingane. Landela imiyalelo yakhe ngokuchanekileyo.
Yintoni omawuyenze ukuba uthatha amayeza amaninzi kakhulu (ukusebenzisa amayeza agqithisileyo)?
Ukuba ukrokrela ukuba uthathe i-overdose, ungoyiki kwaye utsalele umnxeba iZiko loLwazi lweePoisons kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko. Okanye, ukuba kunokwenzeka , yiya kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane ngokukhawuleza.
Kuthekani ukuba ndiphoswa lidosi leyeza?
Ukuba ulibele ukuthatha idosi, yithathe kwangoko xa ukhumbula. Kodwa ukuba kungaphantsi kweeyure ezi-6 ngaphambi kokuba uthathe idosi elandelayo, yitsibe idosi oyiphosileyo. Thatha nje idosi elandelayo ngexesha elicwangcisiweyo. Ungaze uthathe iidosi ezimbini ngaxeshanye ukuze ubuyisele idosi oyilibeleyo.
Amanye amayeza anokusebenzisana nalo mayeza (Ukusebenzisana kwamayeza)
Eli yeza lisenokusebenzisana namanye amayeza. Ngoko ke, kubalulekile ukuxelela ugqirha wakho ngawo onke amayeza owasebenzisayo (kuquka iivithamini, amayeza ezityalo, kunye nezongezo). Le theyibhile ingezantsi ichaza oku ngakumbi.
| Uhlobo lweziyobisi | Inkcazo/Imizekelo |
|---|---|
| Kuphephe ukuzithatha zonke ezi zinto kunye. | |
| Amanye amayeza anikwayo ukuze alungelelane | I-Carbamazepine, iPhenobarbital, iPhenytoin |
| Amayeza esifo sephepha | I-Rifampin, i-Rifabutin |
| Imifuno | I-St. John's Wort |
| Isiselo | Ijusi yegrapefruit |
| Ezi zinokubangela iingxabano (zisetyenziswe kuphela phantsi kwengcebiso kagqirha) | |
| Amanye amayeza okubulala iintsholongwane | IClarithromycin, iErythromycin, iTelithromycin |
| Izinto ezilwa nokungunda | I-Fluconazole, i-Itraconazole, iKetoconazole, iPosaconazole, iVoriconazole |
| Amayeza anikwa emva kokufakelwa | I-Cyclosporine, i-Everolimus, i-Sirolimus, i-Tacrolimus |
| Iyeza lesifo sentliziyo | I-Digoxin |
Iziphumo ebezingalindelekanga ezinokubakho xa uthatha iyeza
Njengalo naliphi na iyeza, eli linokubangela iziphumo ebezingalindelekanga kwabanye abantu. Ezinye zinzima, ezinye zincinci.
| Uhlobo lwesiphumo esibi | Iimpawu |
|---|---|
| Iziphumo ebezingalindelekanga ezinzulu ekufuneka zixelwe kugqirha ngoko nangoko | |
| Iimpendulo ze-Allergic | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi, ubunzima bokuphefumla. |
| Utshintsho lombono | Umbono ofipheleyo, utshintsho kumhlophe emehlweni (ii-cataracts). |
| Iimpawu Zokwenzakala Kwesibindi | Umchamo otyheli okanye omdaka omnyama, ukutyheli kwamehlo okanye ulusu (i-jaundice), ukungabi namdla wokutya, isicaphucaphu, iintlungu kwicala eliphezulu lasekunene lesisu, indle ekhanyayo, ukudinwa okungaqhelekanga. |
| Iziphumo ebezingalindelekanga eziqhelekileyo ekufuneka zixelwe kugqirha ukuba ziyaqhubeka | |
| Intloko ebuhlungu | Intloko ebuhlungu ngokubanzi. |
| Isiyezi | Ukuziva unesizungu. Kuphephe ukuqhuba. |
| Isicaphucaphu | Ukuziva ngathi uhlanza. |
| Iingxaki zeSinus | Ukuxinana kwempumlo, umkhwinya. |
Ukuba ufumana naziphi na ezinye iimpawu ezingaqhelekanga ezingakhankanywanga kolu luhlu, xelela ugqirha wakho ngazo.
Umyalezo Wokuya Ekhaya
- I-Tezacaftor; I-Ivacaftor (iSymdeko) liyeza elikhethekileyo elinikwa izifo ezithile zemfuza ze-Cystic Fibrosis.
- Eli yeza lifanele lisetyenziswe rhoqo kunye nesidlo esinamafutha .
- Musa ukusela ijusi yegrapefruit ngokupheleleyo ngelixa usebenzisa eli yeza.
- Yazisa ugqirha wakho ngazo zonke ezinye iziyobisi ozisebenzisayo.
- Ukuba ubona naziphi na iimpawu zokonakala kwesibindi, ezinje ngotshintsho embonweni okanye ukutyheli kolusu , funa ingcebiso kagqirha ngokukhawuleza.
- Eli yeza lelakho wedwa. Ungaze ulinike omnye umntu.
- Musa ukuthandabuza ukubuza ugqirha wakho malunga neengxaki.
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