Ukuba wena okanye umntu omaziyo une-depression, ugqirha wakho usenokuba ukunike amayeza ahlukeneyo. Nangona amayeza amatsha esetyenziswa rhoqo kule mihla, ngamanye amaxesha kufuneka usebenzise amayeza amadala, kodwa abaluleke kakhulu. Abanye abantu bafumana iziphumo kula mayeza. Namhlanje, siza kuthetha ngelinye lamayeza anjalo, amadala kancinci, kodwa ayimfuneko, i-tricyclic kunye ne-tetracyclic antidepressants.
Zithini ezi ziyobisi ze-tricyclic kunye ne-tetracyclic antidepressants?
Ngamafutshane, la ngamanye amayeza okuqala afunyenweyo okunyanga ukudakumba. Aye asetyenziswa ukususela ngeminyaka yoo-1950. Umahluko phakathi kwala magama mabini kukwakheka kwawo ngamakhemikhali. Ii-Tricyclics zinezangqa ezintathu (tri = three) kwisakhiwo sazo samakhemikhali, ngelixa ii-tetracyclics zinezangqa ezine (tetra = 4). Kodwa zombini zisebenza emzimbeni ngendlela efanayo.
Oogqirha abawacebisi kakhulu la mayeza kule mihla. Oku kungenxa yokuba kuye kwavela amayeza amatsha afana ne -SSRIs (Selective Serotonin Reuptake Inhibitors) aneziphumo ebezingalindelekanga ezimbalwa. Kodwa, khawucinge ukuba uzame amayeza amatsha angaphezu kwelinye kodwa awasebenzanga. Kwimeko enjalo, ugqirha wakho unokuzama elinye lala mayeza amadala.
La mayeza ayichaphazela njani ingqondo?
Kukho iikhemikhali ezikhethekileyo engqondweni yethu ezilawula imood. Ezi sizibiza ngokuba zii-neurotransmitters. I-Serotonin kunye ne -norepinephrine zezona zimbini ze-neurotransmitters ziphambili. Amanqanaba ezi zinto anokuba phantsi engqondweni yomntu onesifo sokudakumba.
Ii-Tricyclic antidepressants (TCAs) zisebenza ngokunyusa amanqanaba e-serotonin kunye ne-norepinephrine engqondweni. Nangona kunjalo, kuba la mayeza echaphazela nezinye ii-neurotransmitters, anomngcipheko ophezulu weziphumo ebezingalindelekanga kuneziyobisi ezintsha ezifana nee-SSRIs. Kwakhona, ukugqithisa kakhulu kuyingozi kakhulu.
| Ii-tricyclic antidepressants (TCAs) ezisetyenziswa rhoqo |
|---|
| I-Amitriptyline |
| I-Amoxapine |
| I-Clomipramine |
| I-Desipramine |
| I-Doxepin |
| I-Imipramine |
| I-Nortriptyline |
| I-Protriptyline |
| I-Trimipramine |
Zithini iziphumo ebezingalindelekanga zale mithi?
Njengoko besitshilo ngaphambili, la mayeza aneziphumo ebezingalindelekanga ezininzi. Yiyo loo nto abantu abaninzi bengafuni ukuwasebenzisa. Kodwa ayinguye wonke umntu ofumana zonke ezi ziphumo ebezingalindelekanga.
Eyona nto ibalulekileyo kukuthetha nogqirha wakho malunga nazo naziphi na iziphumo ebezingalindelekanga ozifumanayo. Musa ukuyeka ukuthatha amayeza ngequbuliso.
Nazi ezinye zeziphumo ebezingalindelekanga eziqhelekileyo:
- Ukozela
- Umbono ofipheleyo
- Ukuqhinwa
- Umlomo owomileyo
- Ukwehla koxinzelelo lwegazi xa usukuma ngequbuliso umi kwindawo yokuma (oku kunokubangela ukuba uzive unesizungu)
- Ukubetha kwentliziyo okungaqhelekanga okanye okukhawulezayo
- Ukudideka kubantu abadala, ingakumbi ukuba kuthathwa iidosi eziphezulu
- Ukuchama okungaphelelanga (Ukugcinwa komchamo)
- Ukwanda komnqweno wokutya kwaye ngenxa yoko utyeba kakhulu
- Ukubila
- Uloyiko
- Ukuvuswa ngokwesondo okanye ukuncipha komnqweno
- Abantu abaneengxaki zokuxhuzula basengozini enkulu yokuxhuzula .
I-Amitriptyline, iDoxepin, i-Imipramine, kunye neTrimipramine zihlala zinokubangela ukozela kunye nokwanda kobunzima. Nangona kunjalo, iNortriptyline kunye neDesipramine zineziphumo ebezingalindelekanga ezimbalwa kunezinye.
Ezinye iimeko zonyango kunye namayeza e-TCA
Ukuba unenye yezi meko zilandelayo zonyango, ngokuqinisekileyo kufuneka uxelele ugqirha wakho ngaphambi kokuba usebenzise eli yeza.
- I-Glaucoma
- Iprostate ekhulisiweyo
- Isifo sentliziyo
- Isifo seswekile
- Izifo zesibindi
- Ukuba i-mesentery yakheke ngaphambili
Nawe ngokunjaloUkuba ukhulelwe okanye uceba ukukhulelwa, qiniseka ukuba uthetha nogqirha wakho.
Ukugqithisa umthamo kunye neengozi zako
Le yeyona nto ibalulekileyo ekufuneka siyilumkele ngala mayeza. Nokuba ukugqithisa kancinci ii-TCA kunokuba yingozi kakhulu ebomini. Ngenxa yoko, oogqirha badla ngokungafuni ukunika la mayeza umntu ocinga ngokuzibulala. Nokuba bayazinikela, bawanika ngamanani amancinci kakhulu, kanye ngeveki.
| Iimpawu ze-TCA Overdose | |
|---|---|
| Ukungahambi kakuhle kwentliziyo | Uxinzelelo lwegazi oluphantsi (iHypotension) |
| Umlomo owomileyo kakhulu | Ukungakwazi ukuchama |
| Ukuphefumla kancinci | Ukungcangcazela kunye nokuxhuzula |
| I-Coma | |
Ingqalelo: Ukuba ukrokrela ukuba umntu usele kakhulu eli yeza, yingxamiseko yezonyango. Fowunela iNkonzo yeeAmbulensi ka-1990 ngaphandle kokulibazisa, okanye umse loo mntu kwiSebe leeNgxamiseko lesibhedlele esikufutshane (ETU) ngokukhawuleza. Kwakhona, ukuba kunokwenzeka, fowunela iZiko loLwazi lweePoison kwiSibhedlele sikaZwelonke saseColombo ukuze ufumane ingcebiso. Xa usiya esibhedlele, ungalibali ukukhankanya igama leyeza umntu alisebenzisileyo.
Ingaba kuyingozi ukuyeka ukuthatha iyeza ngequbuliso?
Ewe, ngokuqinisekileyo. Nokuba uzive ungcono okanye ukhathazwa ziziphumo ebezingalindelekanga, musa ukuyeka ukuthatha eli yeza ngequbuliso ngaphandle kokubonisana nogqirha wakho.Ukuba wenza njalo, ungaziva ungakhululekanga ngenxa yendlela umzimba wakho osabela ngayo kuyo (iimpawu zokurhoxa).
Oku akubangelwa kukuba uxhomekeke kwiziyobisi. Eli yeza alikhobokisi. Kodwa, umzimba wakho nengqondo yakho ziqhelene naloo khemikhali, ngoko ke xa iphela ngequbuliso, kuthatha ixesha ukuba umzimba uqhele.
Iimpawu ezinokwenzeka xa iyeza liyekisiwe
- Ukucaphuka, ukucaphuka
- Isicaphucaphu
- Ukubila
- Iintlungu zomzimba, ukuziva umkhuhlane
- Ukungalali
- Umzimba ongenabomi
- Intloko ebuhlungu
Ngoko ke, ukuba kufuneka uyeke ukusebenzisa amayeza, kufuneka uyenze loo nto ngokunciphisa kancinci kancinci umthamo, ulandela imiyalelo kagqirha wakho .
Umyalezo Wokuya Ekhaya
- Ii-Tricyclic antidepressants (TCAs) ziluhlobo oludala lwamayeza okudakumba, kodwa ziluncedo kakhulu kwabanye abantu.
- Ezi zinomngcipheko ophezulu kancinci weziphumo ebezingalindelekanga kunamayeza amatsha. Thetha ngokukhululekileyo nogqirha wakho ngale nto.
- Ukuba unezinye izifo (ezifana nesifo sentliziyo, i-glaucoma), qiniseka ukuba wazise ugqirha wakho ngaphambi kokuba usebenzise eli yeza.
- Ungaze uyeke ukuthatha eli yeza ngequbuliso ngaphandle kokubonisana nogqirha wakho. Ukwenza njalo kunokubangela ukungakhululeki emzimbeni wakho.
- Ukugqithisa umthamo kuyingozi kakhulu. Yimeko engxamisekileyo yezonyango. Ukuba ukrokrela into enjalo, yiya esibhedlele ngokukhawuleza.
- Nyamekela impilo yakho yengqondo. Thetha nogqirha wakho ukuba kukho naziphi na izinto ezikuxhalabisayo.
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