Isifo i-Alzheimer's siwukwesaba abantu abaningi abanakho engqondweni yabo. Sonke siyazibuza ukuthi thina noma othile esimthandayo sizoba nalesi sifo. "Ingabe lesi yisifo esizuzwe njengefa?", "Kungenzeka yini ukuthi nami ngisithole?" Imibuzo efana nale cishe isengqondweni yakho. Ngakho-ke namuhla, ake sixoxe ngokuthi yiziphi izimbangela zangempela zesifo i-Alzheimer's, okungukuthi, yiziphi izici eziyingozi.
Kwenzekani ebuchosheni ngesifo i-Alzheimer's?
Kalula nje, isifo i-Alzheimer's yisimo lapho amangqamuzana obuchopho efa kancane kancane. Ososayensi bathole izizathu ezimbili eziyinhloko zalokhu. Cabanga ngobuchopho bethu njengomuzi omkhulu, kanti amangqamuzana ezinzwa ayizindlu ezikulowo muzi. Lezi zindlu zidinga ukuxhumana ukuze idolobha lisebenze kahle.
1. Ama-Beta-amyloid plaque: Lawa afana nalawo maqoqo anamathelayo, okunzima ukuwasusa "odoti" aqoqana emigwaqweni yabahamba ngezinyawo phakathi kwezindlu. Ebuchosheni obuphilile, lawa maprotheni ayaphuka futhi asuswe. Kodwa esifweni i-Alzheimer's, ayakha futhi akhe ama-plaque. Lokhu kuphazamisa ukuxhumana phakathi kwamaseli.
2. Ukuxinana kwe-neurofibrillary (tau): Cabanga ngalokhu njengento ephazamisa uhlelo lokuhambisa imiyalezo ngaphakathi endlini yakho. Kwakhiwa yiprotheni ebizwa ngokuthi i-tau. Lokhu kumisa ukuthuthwa kwezakhamzimba nezinto ezibalulekile ngaphakathi kwamaseli akho.
Lezi zinhlayiya kanye nama-tangles kuphazamisa ukuxhumana phakathi kwamangqamuzana obuchopho. Ngokuhamba kwesikhathi, lawa maseli alimele ayafa. Ubuchopho bube sebuqala ukuncipha kancane kancane. Yilokhu okubangela izimpawu ezifana nokukhohlwa, ubunzima bokukhuluma, ukudideka, kanye nokushintsha kokuziphatha .
Ingabe lesi isifo esizuzwe njengefa?
Lokhu kuyinto abantu abaningi abayesabayo. Yiqiniso, kukhona ukuxhumana okuthile kwezakhi zofuzo. Uma othile emndenini wakho oseduze (njengomama, ubaba, noma umfowenu noma udadewabo) enesifo i-Alzheimer's, kungenzeka ukuthi ube naso. Kodwa lokho akusho ukuthi nakanjani uzosithola.
Ososayensi bathole i-gene ebizwa ngokuthi `(Apolipoprotein E - APoE)`. Uma une-`(APoE4)` yale gene, kungenzeka ukuthi unesifo kunabanye. Kodwa akuwona wonke umuntu onale gene othola lesi sifo, futhi akuwona wonke umuntu ongenalo le gene ozothola lesi sifo.
Akuvamile kakhulu ukuthi abantu abangaphansi koyedwa kwabayi-100 abanesifo i-Alzheimer's bangahlakulela lesi sifo ngenxa yokuguquka kwezakhi zofuzo ezithile. Lokhu kubizwa ngokuthi "Isifo i-Alzheimer's somndeni esiqala ekuqaleni". Singaqala eminyakeni ephakathi.
Ngakho-ke, ungakhathazeki uma othile emndenini wakho enalesi sifo. Ezimweni eziningi, akuzona nje izakhi zofuzo eziyimbangela. Indlela yethu yokuphila nendawo esikuyo nayo idlala indima enkulu kuso.
Izici eziyinhloko zengozi yesifo i-Alzheimer's
Isifo i-Alzheimer's asisona isifo esibangelwa imbangela eyodwa. Siyinhlanganisela yezinto eziningi, okuhlanganisa izakhi zofuzo, indlela yokuphila, kanye nendawo ezungezile. Ake sibheke izinto eziyinhloko eziyingozi.
Ukuguga
Ukukhohlwa akuyona into evamile yokuguga. Kodwa-ke, ingozi yokuthola isifo i-Alzheimer iyanda njengoba umuntu ekhula. Le ngozi ivame ukwenzeka ngemva kweminyaka engu-65.
Ukulimala Ekhanda
Umuntu olimale ebuchosheni ngemuva kweminyaka engu-50 usengozini enkulu yokuthola isifo i-Alzheimer's, ikakhulukazi eminyakeni emibili yokuqala ngemva kokulimala.
I-Down Syndrome
Abantu abane-Down syndrome basengozini enkulu yokuthola isifo i-Alzheimer's ngoba i-gene eyenza ama-amyloid plaque, esikhulume ngawo ngaphambili, itholakala ku-chromosome eyengeziwe.
| Isici sengozi/isimo esihlobene | Ubudlelwano nesifo i-Alzheimer's |
|---|---|
| I-cholesterol ephezulu kanye nomfutho wegazi ophezulu | Lezi zimo zingalimaza imithambo yegazi ebucayi ebuchosheni. Lokhu kunciphisa igazi nezakhamzimba ezifinyelela ebuchosheni, okungalimaza amangqamuzana obuchopho. Okuhle enhliziyweni nakho kuhle ebuchosheni. |
| Isifo sikashukela | Abantu abanesifo sikashukela basengozini enkulu yokuthola i-Alzheimer's. Ngezinye izikhathi, amangqamuzana obuchopho aba namandla okumelana ne-insulin. Ngenxa yalesi sizathu, abanye ososayensi babiza i-Alzheimer's ngokuthi "uhlobo lwesithathu lwesifo sikashukela." |
| Ukuphefumula komoya ngesikhathi sokulala | Ukulala kubalulekile empilweni yobuchopho. I-sleep apnea inciphisa inani lomoya-mpilo ofinyelela ebuchosheni. Uma ingelashwa, yandisa ingozi ye-Alzheimer's. |
| Ukulahlekelwa Yizindlebe | Ukulahlekelwa ukuzwa kunganciphisa ukusebenza kwezinye izingxenye zobuchopho. Kuphinde kwandise ingozi yokuhlukaniswa nabantu ngenxa yokulahlekelwa ukuzwa. Ukusebenzisa izinsiza zokuzwa kunganciphisa le ngozi. |
| Ukubhema nokuphuza utshwala ngokweqile | Ubuthi obukugwayi bulimaza amangqamuzana. Ukuphuza utshwala ngokweqile kunganciphisa izindawo zobuchopho ezihilelekile ekukhumbuleni. Zombili lezi zinto zandisa kakhulu ingozi ye-Alzheimer's. |
| Ukukhuluphala ngokweqile | Ukukhuluphala ngokweqile kungabangela ukuvuvukala okungapheli emzimbeni. Lokhu kungalimaza namaseli obuchopho. Ukukhuluphala ngokweqile kwandisa nezinye izici eziyingozi, njengesifo sikashukela kanye nomfutho wegazi ophezulu. |
| Ukucindezeleka kanye nokuzihlukanisa nabantu | Kukhona ukuxhumana phakathi kokucindezeleka kanye ne-Alzheimer's. Mhlawumbe lokhu kokubili kunezimbangela ezifanayo. Futhi, isizungu kanye nokuzihlukanisa nabantu akukuhle empilweni yobuchopho. |
Kuxoxwe kodwa akukaqinisekiswa amaqiniso okwamanje
Nakuba amahemuhemu esakazeke ngezinto ezithile, akukakafakazelwa ngokwesayensi ukuthi athinta ngqo isifo i-Alzheimer's.
- I-Aluminium: Esikhathini esidlule, kwakukhona inkolelo yokuthi ukusebenzisa izinto ze-aluminium kwakubangela i-Alzheimer's. Kodwa-ke, izifundo eziningi manje zibonisa ukuthi inani le-aluminium elisetshenziswa ngobuningi obujwayelekile alinawo ubungozi.
- Amagciwane: Ucwaningo luyenziwa ukuze kutholakale ukuthi kukhona yini ukuxhumana phakathi kwezinhlobo ezithile zamagciwane (isib. igciwane le-herpes) kanye ne-Alzheimer's, kodwa akukho siphetho esiqondile esifinyelelwe.
Izinto esingazenza ukuze sinciphise ingozi
Nakuba kungekho ndlela yokuvimbela isifo i-Alzheimer's ngo-100%, kunezinto eziningi esingazenza ukuze sinciphise ingozi.
1. Vivinya umzimba njalo: Uma uzivocavoca, ubuchopho bakho buthola ukugeleza kwegazi okungcono kanye nomoya-mpilo. Lokhu kuthuthukisa impilo yobuchopho.
2. Yidla ukudla okunempilo kwenhliziyo: Nciphisa ukudla okunamafutha amaningi, amafutha, noshukela, bese udla imifino eminingi, izithelo, kanye nemifino eluhlaza. Okuhle enhliziyweni nakho kuhle ebuchosheni.
3. Lala ngokwanele: Kubalulekile ukulala kahle amahora angu-6-8 ngosuku. Ubuchopho buzihlanza ngesikhathi sokulala.
4. Inselele ubuchopho bakho: Funda okuthile okusha, funda izincwadi, uxazulule amaphazili, yiba nobudlelwano nabantu. Ukugcina ubuchopho bakho busebenza kubaluleke kakhulu.
5. Lawula ezinye izifo: Uma unezifo ezifana nesifo sikashukela, umfutho wegazi ophakeme, noma i-cholesterol, landela imiyalelo kadokotela wakho ngokucophelela . Ukuzilawula kahle kungasiza futhi ekunciphiseni ingozi yakho ye-Alzheimer's.
Umlayezo Wokuya Nawe Ekhaya
- Isifo i-Alzheimer's asibangelwa yimbangela eyodwa. Siyinhlanganisela yezinto eziningi, okuhlanganisa izakhi zofuzo, indlela yokuphila kanye nezimo zempilo.
- Ukuthi nje othile emndenini wakho ube nalesi sifo akusho ukuthi uzosithola. Indlela yethu yokuphila ingaba nomthelela omkhulu kunezakhi zofuzo.
- Kukhona ukuxhumana okuqinile phakathi kwempilo yenhliziyo nempilo yobuchopho. Ukwenza izinto ezinhle enhliziyweni kuvikela nobuchopho.
- Uma unemibuzo noma ukungabaza ngalokhu, khuluma nodokotela wakho ngakho ngokukhululekile . Angakunikeza iseluleko esingcono kakhulu.
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