Ingabe amathambo akho nawo abuthakathaka? Ake sixoxe nge-Fibrous Dysplasia!

Wake wacabanga ukuthi amathambo ethu ngezinye izikhathi angaba buthakathaka futhi akhule ngezindlela ezingavamile? Namuhla sizokhuluma ngesimo samathambo esingajwayelekile, kodwa okubalulekile ukwazi ngaso. Sibizwa ngokuthi i-Fibrous Dysplasia . Ungase ube nalesi simo ngaphandle kwezimpawu. Ngakho ake sixoxe ngakho ngemininingwane ethe xaxa, akunjalo?

Kuyini i-Fibrous Dysplasia?

Kalula nje, i-fibrous dysplasia yisimo esingavamile lapho izicubu ezingavamile ze-fibrous (ezifana nezibazi) zikhula emizimbeni yethu esikhundleni sezicubu zethambo ezinempilo. Lesi zicubu ezintsha aziqinile njengethambo langempela. Ngenxa yalokho , amathambo aba buthakathaka futhi athambekele kakhulu ekuqhekekeni (ukuqhekeka).

Lesi simo singathinta noma yiliphi ithambo emzimbeni, kodwa sivame ukuthinta:

• Kuye ethanjeni lethanga (ithambo elikhulu kunawo wonke engxenyeni engenhla yomlenze wethu - `i-femur`)
• Ethanjeni lomlenze (ithambo elingaphansi kwedolo lomlenze - `i-tibia`)
• Ezimbanjeni
• Ugebhezi (kufaka phakathi amathambo obuso)
• Ithambo lengalo engenhla (i-humerus)

Izindaba ezinhle ukuthi lokhu akulona umdlavuza (ongemuhle) . Lokho kusho ukuthi ngeke kusabalale kwamanye amathambo emzimbeni. Lokho kuyasiza kancane, akunjalo?

Ingabe zikhona izinhlobo ze-fibrous dysplasia?

Yebo, odokotela bahlukanisa lesi simo sibe izinhlobo ezimbili eziyinhloko, kuye ngenani lamathambo athintekile:

1. I-Monostotic fibrous dysplasia: Lokhu kuthinta ithambo elilodwa kuphela.

2. I-polyostotic fibrous dysplasia: Lokhu kuthinta amathambo amaningana .

Ngezinye izikhathi, uma unesifo esingavamile esibizwa ngokuthi ``McCune-Albright syndrome``, ungase ube ne-polyostotic fibrous dysplasia. Lesi sifo sithinta amathambo ethu, isikhumba, kanye ``nohlelo lwe-endocrine`` (uhlelo olulawula ama-hormone).

Ziyini izimpawu zalokhu?

Akuwona wonke umuntu one-fibrous dysplasia onezimpawu. Yingakho kunzima ukucabanga. Abanye abantu bathola ukuthi banalesi simo ngengozi uma bethathwa i-X-ray ngesinye isizathu.

Kodwa-ke, kulabo abathola izimpawu, okulandelayo kungenzeka:

• Ukuphuka kwamathambo njalo: Ngisho nokuwa okuncane kungaphula ithambo.
• Ubuhlungu bamathambo: Ungase uzwe ubuhlungu obukhulu ethanjeni elithintekile. Lobuhlungu bungakhula kancane kancane futhi ngezinye izikhathi bube bukhulu.
• Izinguquko esimweni samathambo: Amathambo angase abonakale evuvukele noma ekhule ngendlela engavamile.
• Ukuvuvukala okungenabuhlungu ezimbanjeni: Abanye abantu bathola ukuvuvukala okufana neqhubu endaweni yezimbambo, kodwa akubuhlungu.
• I-Scoliosis: Umgogodla ungase ugobe uye ohlangothini olulodwa.
• Amehlo avelele:Uma amathambo ekhanda ethintekile, amehlo angase abonakale ephuma phambili.
• Ukunyakazisa umhlathi: Uma amathambo omhlathi ethintekile, umhlathi ungase unyakazise ohlangothini olulodwa.
• Amazinyo ahamba noma angahleleki kahle: Amazinyo angase ahambe noma angahlangani kahle ngenxa yezinguquko ethanjeni lomhlathi.
• Ukuminyana kwamakhala: Uma amathambo obuso ethintekile, ungase ube nokuminyana kwamakhala njalo.

Ngokuvamile, labo abanamathambo amaningi athintekile (i-polyostotic) banezinkinga eziningi kunalabo abanethambo elilodwa kuphela elithintekile (i-monostotic).

Kungani i-dysplasia ye-fibrous yenzeka?

Lokhu kuyinkimbinkimbi kancane. Lesi simo sibangelwa ukuguquka okungahleliwe kwesakhi sofuzo esibizwa ngokuthi `i-GNAS1` emzimbeni wethu ngemva kokuba sikhulelwe esibelethweni. Lokhu kuguquka kwesakhi sofuzo kuthinta amangqamuzana ethu abizwa ngokuthi `ama-osteoblast`. Ama-osteoblast awuhlobo olukhethekile lweseli olusiza amathambo ethu ukuba akhule futhi akheke. Ngakho-ke, lapho ukusebenza kwala maseli kuphazamiseka, kwakheka izicubu ezingavamile ze-fibrous.

Kubaluleke kakhulu: Odokotela abasazi kahle ukuthi kungani lokhu kuguquka kwezakhi zofuzo kwenzeka. Futhi, akulona ufuzo. Lokho kusho ukuthi noma ngabe unalesi simo, izingane zakho ngeke zisithole njengefa. Akulona iphutha lakho noma yini. Ngakho ungakhathazeki ngakho, kulungile?

Yiziphi izinkinga ezingabangelwa yilokhu?

Inkinga eyinhloko ebonakala ku-fibrous dysplasia ukuthi amathambo aphuka kalula, ngoba izicubu ezisanda kwakheka aziqinile njengethambo langempela.

Ngaphezu kwalokho, uma lesi simo sithinta amathambo azungeze amehlo noma amathambo azungeze izindlebe, kungase kube nokuphazamiseka kokuzwa noma kokubona . Ngakho-ke, kubalulekile ukuqaphela izimpawu ezinjalo.

Odokotela bakuthola kanjani lokhu?

Uma unezinhlungu zamathambo noma ezinye izimpawu ezingavamile, kufanele ubonane nodokotela. Udokotela uzoqala akubuze ngezimpawu zakho, njengokuthi sezinesikhathi esingakanani zikhona. Ngemuva kwalokho uzokwenza ukuhlolwa ngokomzimba, ikakhulukazi ebheka eduze indawo lapho kukhona khona ubuhlungu.

Ngaphezu kwalokho, kungenzeka ukwenza izivivinyo ezifana nalezi:

• Ukuhlolwa kwegazi nomchamo: Lokhu kuhlolwa kwenziwa ukuze kubonwe ukuthi amazinga athile e-enzyme aphakeme yini. Uma ephakeme, lokhu kunganikeza umbono mayelana nokukhula okungavamile kwezicubu ze-fibrous.
• Ukuhlolwa kwezithombe:
• Ama-X-ray: Lawa angabona izicubu ezingavamile, ukwaphuka, kanye noshintsho esimweni samathambo.
• Ukuskena kwe-CT kanye ne-MRI: Lokhu kungaveza izithombe ezicacile nezinemininingwane eminingi kune-X-ray. Kusiza ekucwaningeni isimo samathambo ngokujulile.
• Ukuhlolwa kwe-biopsy:Ngezinye izikhathi, uma udokotela enokungabaza, uzothatha ingxenye encane kakhulu yezicubu ezingavamile noma izicubu zethambo ezinempilo bese eyihlola ngaphansi kwe-microscope. Lokhu kubizwa ngokuthi i-biopsy. Yilokhu okuqinisekisa ngokuqinisekile lesi sifo.

Iphathwa kanjani i-fibrous dysplasia?

Izindlela zokwelapha zincike ezimpawini zakho, ubukhulu besimo, nokuthi sithinta kanjani impilo yakho. Akuwona wonke umuntu odinga uhlobo olufanayo lokwelashwa.

Izindlela zokwelapha eziyinhloko yilezi ezilandelayo:

1. Ukuqaphela: Uma ungenazo izimpawu, noma uma izimpawu zakho zingembi kakhulu, udokotela wakho angase angakuniki ukwelashwa okuthile, kodwa angase aqaphe amathambo akho ngokuhlolwa njalo (ama-aphoyintimenti okulandelela). Lokhu kwenzelwa ukubona ukuthi kukhona yini ushintsho.

2. Imithi: Imithi ethile (isib. ama-bisphosphonates) inganikezwa ukuqinisa amathambo, ukunciphisa ingozi yokuphuka kwamathambo, nokulawula ubuhlungu.

3. Ukuqinisa amathambo: Ngezinye izikhathi ungase ucelwe ukuthi ugqoke ama-braces ukuze usekele amathambo abuthakathaka, uwasize akhule kahle, futhi uvimbele ukukhubazeka.

4. Ukuhlinzwa:

• Qinisa amathambo aphuka njalo.
• Lungisa amathambo aphukile kakhulu.
• Uma isimo samathambo siphambene, silungise.
• Ngezinye izikhathi, kungadingeka ukwenza "ukufakelwa kwamathambo." Lokhu kusho ukuthatha ingxenye yethambo eliphilile kwenye ingxenye yomzimba bese uyifakela ethanjeni elithintekile.

Kufanele ngimbone nini udokotela?

Uma ubuhlungu emathanjeni bungapheli, qiniseka ukuthi ubona udokotela. Kungenzeka ukuthi akubangelwa yi-fibrous dysplasia, kodwa kubalulekile ukuthola imbangela.

Uma usuvele wazi ukuthi une-fibrous dysplasia, bona udokotela wakho uma:

• Uma uzizwa sengathi izimpawu zakho ziya ziba zimbi kakhulu .
• Uma unomuzwa wokuthi ukwelashwa okutholayo akusizi .

Okubalulekile: Ngenxa yokuthi i-fibrous dysplasia yenza amathambo abe buthaka, uma uwa, ushaye into enzima, noma ungena engozini yemoto, hamba uye egumbini lezimo eziphuthumayo esibhedlela esiseduze ngokushesha. Kunobungozi obukhulu bokuphuka.

Uma ngine-fibrous dysplasia, yini okufanele ngiyilindele?

Kunzima ukunikeza impendulo eyodwa kulo mbuzo, ngoba i-fibrous dysplasia ithinta wonke umuntu ngendlela ehlukile. Abanye abantu bangaphila ngaphandle kwezinkinga ezinkulu. Abanye kungadingeka baqaphele kakhudlwana futhi bathole ukwelashwa.

Kodwa into eyodwa eqinisekile: i-fibrous dysplasia iyisimo esingamahlalakhona.Lokho kusho ukuthi akusona isifo esingelapheki ngokuphelele, kodwa kunezindlela zokwelapha ezingasiza ekunciphiseni umthelela esinawo empilweni yakho.

Uma uthola ukuthi unalesi simo, ungase uzizwe umangale futhi ukhathazekile kancane. Lokho kujwayelekile. Kodwa khumbula, awuwedwa. Khuluma ngokukhululekile ngalokhu nodokotela wakho. Uzokuchazela ukuthi yini ongayilindela nokuthi yiziphi izindlela zokwelapha ezifanele wena.

Okokugcina, izinto okufanele uzikhumbule (Umyalezo Wokuya Ekhaya)

Kulungile, ngakho-ke masikhumbule la maphuzu njengesifinyezo se-fibrous dysplasia esikhulume ngayo namuhla:

• I-Fibrous dysplasia yisifo samathambo esingavamile.
• Kulokhu , kwakheka izicubu ezibuthakathaka, ezinemicu esikhundleni sethambo eliphilile.
• Lokhu kungabangela ukuthi amathambo aphuke kalula.
• Abanye abantu bangase bangabi nazo izimpawu .
• Lokhu akusiwo umdlavuza, futhi akusiwo ufuzo.
• Nakuba kungekho ikhambi eliphelele, kunezindlela zokwelapha zokulawula izimpawu nokunciphisa umthelela empilweni.
• Uma unezinhlungu emathanjeni noma ezinye izimpawu ezisolisayo, qiniseka ukuthi ufuna iseluleko sezokwelapha.

Ngiyethemba ukuthi lolu lwazi luzokusiza. Uma uneminye imibuzo mayelana nalokhu, ungangabazi ukubuza udokotela wakho. Hlala uphilile!

I- Fibrous dysplasia, isifo samathambo, ukuphuka kwamathambo, ubuhlungu bamathambo, i-GNAS1 gene, impilo yamathambo, izifo ezingavamile